양독백호탕으로 호전된 소양인 사지 말단부위 냉증 환자 1례 보고

오현주,황민우,Oh, Hyun-Joo,Hwang, Min-Woo 사상체질의학회 2017 사상체질의학회지 Vol.29 No.3

Objectives The purpose of this study was to report significant improvement of peripheral coldness in patient, who was diagnosed with 'Soyangin Chest-heat symptomatic pattern' and applied medication based on Sasang Constitutonal medicine. Methods The patient was treated with herbal medications, according to his own symptomatology. The objective outcome was measured by thermography and the subjective sensation was assessed by using Visual Analogue Scale (VAS). Results The symptoms of peripheral coldness improved remarkedly without any side effects. Accessory symptoms and original symptoms also changed for the better. Conclusions This results show that it is available that peripheral coldness is treated with herbal medications according to Sasang Constitutional medicine, especially ingenious in terms of the fact that some patient can be diagnosed with heat-based condition on the basis of original symptoms, although his/her chief complaint is classified as cold pattern.

건칠 추출물이 Streptozotocin으로 당뇨를 유도한 흰쥐에 미치는 영향

오현주,고성규,신용철,Oh, Hyun-Joo,Ko, Seong-Gyu,Shin, Yong-Cheol 대한예방한의학회 2006 대한예방한의학회지 Vol.10 No.1

Rhus verniciflua Stokes(RVS) has been widely used as a food and traditional herbal medicine in Korea. RVS has been reported that the extract from its wood and fruit has strong antioxidant activity and anticancer effect but there is little information on Lacca Sinica Exsiccata(LSE), the resin of RVS, as a medicinal use. The aim of this study was to evaluate the antidiabetic effect of ethanol-eluted extract of LSE on streptozotocin(STZ) - induced diabetic rats. Diabetes was induced in male Sprague-Dawley rats with STZ injection. Oral administration of LSE extract(50mg or 100mg/kg of body weight/day) was given to diabetic group. During 4 weeks of experiment, diabetic rats showed significant weight loss and decreasing feed efficiency ratios(FER) compared with normal rats, while the diabetic group orally fed with LSE extract showed a trend of decreasing weight loss and a significant increase of FER(p<0.05). In 4 weeks after induction of diabetes, diabetic rats showed an increase in weight of liver, kidney and heart, whereas the diabetic rats administered with LSE extract showed a reduction in the weight of heart. Blood glucose level was decreased in diabetic rats treated with LSE extract, but it was not statistically significant. Glutamic oxaloacetic transaminase, Glutamic pyruvate transaminase and total cholesterol levels were lower in the diabetic group treated with LSE extract than in untreated diabetic group, but not significant. These results present that LSE may partly have antidiabetic effect and may protect against the development of diabetic heart complications resulting from impaired glucose metabolism.

한국표준질병사인분류의 개정에 관하여

오현주,OH, Hyun-Ju 한국생명보험의학회 2008 保險醫學會誌 Vol.27 No.1

The 5th revision of Korean Classification of Diseases(KCD) became effective on January 1, 2008. It has reflected the changes made to the tenth revision of International Classification of Diseases (ICD-10) between 1998 and 2005 and the suggestions of academic and related societies in Korea. Two important alterations seem to have a major implication in the insurance industry. One would be the official introduction of a Korean version of International Classification of Diseases for Oncology, third edition(ICD-O-3). The borderline ovarian tumor is classified as a borderline neoplasm, which was classified as a malignant neoplasm in the previous edition of International Classification of Diseases for Oncology. The other would be the appearance of non-C-code malignant neoplasm for the diseases, such as polycythemia vera, newly classified as a malignant neoplasm by the current edition of International Classification of Diseases for Oncology. The National Office of Statistics(NSO) adopted the way of implementation used in the Australian Modification of International Classification of Diseases(ICD-10-AM), instead of assigning them into corresponding C code. Overall, the changes made in this revision doesn't seem to have a serious impact on the insurance industry since it has only reflected updates made to ICD-10.

기능성 소화불량증이 호전된 소양인 비수한표한병 환자 3례 보고

오현주,홍승민,황민우,Oh, Hyun-Joo,Hong, Seung-Min,Hwang, Min-Woo 사상체질의학회 2016 사상체질의학회지 Vol.28 No.3

Objectives The purpose of this study was to report significant improvement of functional dyspepsia in 3 patients, who were diagnosed with 'Soyangin Spleen Cold-based Exterior Cold disease' and applied medication based on Sasang Constitutonal medicine.Methods The patients were treated with herbal medications, according to their own constitution. The objective outcome was measured by body composition analyzer and Gastrointestinal Symptom Rating Scale (GSRS), and the subjective sensation was assessed by using Visual Analogue Scale (VAS).Results The symptoms of functional dyspepsia improved remarkedly in all respects, without any side effects. Original symptoms also changed for the better.Conclusions This results show that it is available that functional dyspepsia is treated with medicines according to Sasang Constitutional medicine.

굴곡-신연기법과 낙차 교정법이 허리 척추사이원반 탈출증 환자의 시각적 상사 척도 및 엉치뼈 각에 미치는 영향

오현주,최석주,이관섭,최지운,Oh, Hyun-Ju,Choi, Seok-Joo,Lee, Kwan-Sub,Choi, Ji-Oun 대한물리치료과학회 2018 대한물리치료과학회지 Vol.25 No.3

Background: In order to find out the effect of therapy methods through Flexion-distraction technique and drop technique on pain, sacral angle of patients with lumbar herniated intervertebral disc targeting patients with lumbar herniated intervertebral disc due to L5-S1. Method: This study was to present the directivity of the therapy method for lumbar herniated intervertebral disc by comparing and analyzing the spinal decompression therapy and provide an effective treatment method to patients with lumbar herniated intervertebral disc by identifying the therapeutic effect of Flexion-distraction technique and drop technique. The research period is March 1, 2018 to June 30, 2018 and subjects are the patients diagnosed as lumbar herniated intervertebral disc due to L5-S1 by their doctor through clinical findings and medical equipment such as X-ray, CT, MRI etc. Among patients who visited and hospitalized in S Orthopaedics located in Daegu and 30 female patients with sacral angle of more than $30^{\circ}$ were randomly classified into 15 people and we carried out treatment three times a week for 8 weeks for 15 people in the experimental group applying Flexion-distraction technique and drop technique and 15 people in the control group applying spinal decompression therapy to compare and analyze the changes in pain, sacral angle of patients with lumbar herniated intervertebral disc. Result: According to the results of this study, changes in the Visual Analogue Scale showed statistically significant differences in both the experimental group and control group(p<.05), while there was statistically significant difference in the comparison between groups before and after measurement of experimental group (p<.05). In the comparison within two groups of sacral angle, both groups showed statistically significant difference(p<.05) but there was no statistically significant difference in the comparison of scores between groups before and after measurement of each group(p>.05). Discussion: All those results the above proved that we need to confirm various benefits of the therapy with the flexion-distraction technique and drop technique, and the findings of the concerned study will possibly become useful information when doctors actually work on a therapy to treat patients with the lumbar herniated intervertebral disc.

Salmonella enteritidis 위장관염에 합병된 급성 비결석성 담낭염 1예

오현주,강현식,강기수,김승형,김봉수,김광식,Oh, Hyun-Ju,Kang, Hyun-Sik,Kang, Ki-Soo,Kim, Seung-Hyung,Kim, Bong-Soo,Kim, Kwang-Sig 대한소아소화기영양학회 2009 Pediatric gastroenterology, hepatology & nutrition Vol.12 No.1

저자들은 평소 건강하던 9세 남아에게서 Salmonella enteritidis 위장관염에 합병된 급성 비결석성 담낭염을 임상증상, 혈액 검사 및 배양 검사, 복부 초음파 검사등을 통하여 진단 할 수 있었다. 또한 항생제 치료와 비수술적 방법인 경피경간 담낭배액술을 통하여 성공적으로 치료 하였기에 이에 보고하는 바이다. We report a rare case of acute acalculous cholecystitis (ACC) caused by Salmonella enteritidis infection in a previously healthy 9-year-old boy. Salmonella enteritidis was isolated from stool and bile culture. The diagnosis of ACC was established upon clinical, laboratory, and ultrasonographic findings. The patient was successfully treated using percutaneous transhepaticcholecystic drainage (PTCCD) in combination with antibiotics therapy.

갑상선 질환자에게 적용한 중재 프로그램에 대한 체계적 문헌고찰 - 국내연구를 중심으로

오현주,조정화,Oh, Hyun-Joo,Cho, Jeong-Hwa 한국융합학회 2021 한국융합학회논문지 Vol.12 No.4

본 연구는 국내 갑상선질환자를 대상으로 한 중재 연구 프로그램의 특성과 결과변수를 분석하기 위한 체계적 문헌고찰 연구이다. 국내 5개의 데이터베이스에서 2019년까지 발표된 문헌을 체계적으로 고찰하였다. 확인한 824편 중 선정기준에 맞는 6편을 추출하였다. 본 연구의 결과 프로그램은 교육, 활동, 상담으로 분류되었다. 교육 및 상담요법은 심리사회적인 변수와 신체생리적인 변수에 유의한 영향을 미치고 있었다. 활동요법은 신체생리적 변수에 유의한 영향을 나타내었다. 본 연구는 국내 갑상선질환자를 위한 다양한 중재 프로그램의 개발과 운영방안에 대한 근거를 제시하였다는 것에 의의가 있으며 향후 갑상선질환자의 신체생리적 기능과 심리사회적 문제를 고려한 융합적 프로그램개발연구에 활용될 수 있을 것이다. This study is a systematic review of literature to analyze the characteristics and outcome variables of intervention research programs for domestic thyroid patients. We systematically reviewed the literature published until 2019 in five domestic databases. Six of the 824 confirmed articles were extracted according to the selection criteria. The results of this study were classified into education, activities, and counseling. Education and counseling therapy had a significant effect on psychosocial and physiological variables. Activity therapy had a significant effect on physiological variables. This study presented the basis for the development and implementation of various intervention programs for domestic thyroid patients and can be used for the study of the convergence program development considering physiological and psychosocial problems of the thyroid patients.

팔당호의 오염퇴적물 분포 조사

오현주,홍종엽,이상득,정문조,Oh, Hyeon-Ju,Hong, Jong-Youb,Lee, Sang-Deuk,Chung, Moon-Jo 대한환경공학회 2000 대한환경공학회지 Vol.22 No.7

수도권의 상수원으로 사용되고 있는 팔당호를 대상으로 34개의 지점에서 깊이별로 퇴적물을 채취하여 퇴적물의 분포 및 오염현황을 조사하였다. 퇴적물의 강열감량과 CODcr, 총인, 총질소 농도를 분석하였고, 호소 수질 환경에 따라 퇴적물에서 재용출 가능성이 있는 인의 함량을 살펴보기 위해 존재형태별로 인을 분석하였다. 퇴적물의 지역별 깊이별 오염도 분석 결과 팔당호의 경우, 퇴적층의 심도에 따른 오염물질 농도 차는 그다지 크지 않았고, 이러한 오염도 분석결과로부터 팔당호 오염 퇴적물 분포도를 작성할 수 있었다. 또한, 호소 심층 환경에서 퇴적물로부터 재용출 가능한 인은 전체의 약 20~30%인 것으로 나타났으며 이러한 결과는 앞으로 관련연구에 기초 자료로 활용될 수 있을 것이다. Status of the contaminated sediments in Lake Paldang was investigated. Sediment samples were taken at 34 points and analyzed in terms of ignition loss, CODer, total P and total N. The contamination level did not show any significant variation with depth of the sediments, which indicated the contaminants were recalcitrant. The type of P in the sediment was analyzed, and the sum of adsorbed P and NAI-P, that can be re-solubilized under the reductive condition, was found to be 20-30% of the total P. From the analysis of the water quality change along with the flowing path, it would be concluded that the effect of the sediments on the water quality is insignificant yet in Lake Paldang. However, long term analysis covering at least four seasons should be continued in order to get a more reliable conclusion. A depth profile map of the sediment in Lake Paldang was provided.

PNF 목 패턴이 전방머리자세를 가진 성인의 목 움직임 및 목 장애 지수에 미치는 영향

오현주,송귀빈,Oh, Hyun-Ju,Song, Gui-Bin 대한고유수용성신경근촉진법학회 2016 PNF and Movement Vol.14 No.3

Purpose: The purpose of this study was to investigate the effects of neck patterns in proprioceptive neuromuscular facilitation (PNF) for neck movement and the neck disability index (NDI) among adults with forward head posture. Methods: Thirty-nine subjects were randomly assigned into two groups. Subjects in the proprioceptive neuromuscular facilitation exercise group (PNFG, n = 20) received 20 minutes of PNF neck pattern (flexion-Rt. lateral flexion-Rt. rotation followed by extension-Lt. lateral flexion-Lt. rotation) 3 times weekly for 4 weeks. Outcomes were measured using absolute rotation angle (ARA), anterior weight bearing (AWB), range of flexion and extension motions (RFEM), and neck disability index (NDI) methods before and after the 4-week intervention period. Results: There were significant effects for the PNFG, pre- and post-intervention, in ARA, AWB, RFEM, and NDI. There were significant differences in ARA, AWB, RFEM, and NDI compared with CG. Conclusion: The results of this study suggest the PNF neck pattern could be beneficial for adults with forward head posture.

Distribution of Disease Severity and Group A Rotavirus Genotypes (VP7 & VP4) in Children with Acute Rotavirus Gastroenteritis

오현주,강현식,강기수,김연우,홍정연,신경수,이진숙,이수현,이근화,조문제,서동인,Oh, Hyun-Ju,Kang, Hyun-Sik,Kang, Ki-Soo,Kim, Youn-Woo,Hong, Jung-Yun,Shin, Kyung-Sue,Lee, Jin-Sook,Lee, Su-Hyun,Lee, Keun-Hwa,Cho, Moon-Je,Suh, Dong-In The Korean Society of Pediatric Gastroenterology 2011 Pediatric gastroenterology, hepatology & nutrition Vol.14 No.2

목적: 저자들은 지역사회에서, 로타바이러스 장염에 걸린 소아들에서 질환의 중증도와 로타바이러스 VP7 유전형과 VP4 유전형의 분포에 대해 알아보고자 하였다. 방법: 2007년 12월부터 2008년 6월까지 로타바이러스 장염으로 병원에 입원한 156명의 소아들에서 대변 샘플을 수집하였다. 모든 환자들에 대한 질환 중증도는 Vesikari 점수를 이용하여 평가하였다. 로타바이러스 ds-RNA를 분리한 후, 역전사 중합효소 연쇄반응과 다중 중합효소 연쇄반응을 이용하여 cDNA를 합성하였다. 마지막으로 유전형을 확인하였다. 결과: 156명의 환자 샘플에서, VP7(G)는 147명(94.2%)에서 확인되었고 VP4(P)는 140명(89.7%)에서 확인되었다. G1 유전형(147명 중 116명; 78.9%)과 P[8] 유전형(140명 중 137명)이 각각 가장 많았다. VP7과 VP4 조합형은 138명에서 확인할 수 있었는데, G1P[8] 조합형이 111명(80.4)으로 가장 많았다. 다른 조합형들은 종류가 다양하였고 분포가 낮았다. 전체 조합형 중 9.4%가 새로운 로타바이러스 백신에 포함되지 않은 것이었다. 로타바이러스 장염의 질환 중중도는 $11.8{\pm}3.3$ ($mean{\pm}2SD$)였다. 전체 환자에서 경증 내지 중등도가 37.8%였고, 중증은 62.2%였다. 결론: 로타바이러스 유전자 조합형 중 가장 흔한 것은 G1P[8]이었다. 새로운 백신에 포함되지 않은 유전자 조합형은 9.4%였다. 로타바이러스 장염으로 입원한 소아들의 질환 중증도분포는 경증과 중등도보다 중증에서 높게 나타났다. Purpose: We aimed to study the distribution of rotavirus genotypes (VP7 and VP4) and disease severity of rotavirus gastroenteritis prevalent in our community. Methods: Stool samples were collected from 156 children who were hospitalized with rotavirus gastroenteritis from December 2007 to June 2008. The disease severity of all patients was scored using the Vesikari scale. After extraction of ds-RNA of the rotavirus, cDNA synthesis using reverse transcription and polymerase chain reaction (RT-PCR) and multiplex PCR was performed. Following this, the final identification of genotypes was performed. Results: Of the 156 samples, VP7(G) and VP4(P) genotypes were identified in 147 (94.2%) and 140 (89.7%) samples, respectively. G1 (116 of 147 samples; 78.9%) and P[8] (137 of 140 samples; 97.9%) were the most prevalent, respectively. Of the 138 samples identified of combination types of VP7 and VP4, G1P[8] (111 samples; 80.4%) was the most prevalent. Other combination types varied with very low distribution rates. 9.4% of genotypes were not included in the new vaccines. The disease severity score was $11.8{\pm}3.3$ ($mean{\pm}2SD$). The distribution of disease severity was mild or moderate in 37.8% and severe in 62.2% of patients. Conclusion: The most prevalent genotype combination of rotavirus was G1P[8] and genotypes not included in the vaccines represented 9.4% in our community. Disease severity distribution of hospitalized children with rotavirus gastroenteritis was higher in the severe than in the mild and moderate categories.