A Case of Atypical Thrombotic Microangiopathy

오지영,박세진,김기환,임범진,정현주,기정혜,김기혁,신재일,Oh, Ji Young,Park, Se Jin,Kim, Ki Hwan,Lim, Beom Jin,Jeong, Hyeon Joo,Ki, Jung Hye,Kim, Kee Hyuck,Shin, Jae Il Korean Society of Pediatric Nephrology 2013 Childhood kidney diseases Vol.17 No.2

We report the case of a 14-year-old girl, diagnosed with atypical thrombotic microangiopathy (TMA). The patient presented with persistent fever, nausea, and newly developed peripheral edema. Her laboratory findings indicated chronic anemia with no evidence of hemolysis, thrombocytopenia, or elevated serum creatinine level. A few days after hospitalization, acute renal failure and fever worsened, and proteinuria developed. On day 40 of hospitalization, she experienced a generalized tonic seizure for 5 min, accompanied by renal hypertension. Brain magnetic resonance imaging revealed posterior reversible leukoencephalopathy syndrome. After steroid pulse therapy, a renal biopsy was performed because of delayed recovery from thrombocytopenia. The biopsy findings showed features of thrombotic microangiopathic hemolysis with fibrinoid change restricted. Current diagnostic criteria for TMA have focused on thrombotic thrombocytopenic purpura and hemolytic uremic syndrome, and diagnosis is based on the clinical presentation and etiology, with the consequence that idiopathic and atypical forms of TMA can be overlooked. Developing effective tools to diagnose TMA, such as studying levels of ADAMTS13 or testing for abnormalities in the complement system, will be the first step to improving patient outcomes. 응고성 미세혈관병증은 빠른 진단이 예후에 중요한 인자이나, 현재의 진단 기준에 따라서는 thrombotic thrombocytopenic purpura, haemolytic uremic syndrome 외의 비전형적인 응고성 미세혈관병증의 진단이 늦어짐에 따라 나쁜 예후를 초래하게 되는 경우가 많다고 보고되어 있다. 본 저자들은 시행한 혈액 검사상 용혈의 증거가 없는 빈혈, 혈소판 감소증 그리고 급성 신부전을 보인 소아 환아에서 신조직 검사를 통해 비특이적 응고성 미세혈관병증을 진단받은 1증례를 보고하고자 한다. 14세 여자 환아는 3주간 지속된 발열, 구역과 전신 부종을 주소로 본원으로 전원되었다. 내원하여 시행한 혈액 검사상 빈혈과 혈소판 감소증을 보였으나, 용혈의 증거는 없었으며, 혈정 크레아티닌이 증가되어 있었다. 내원 이후 급성 신부전과 발열은 지속적으로 진행되었으며, 소변 검사상 단백뇨가 발생하였다. 환아는 내원 40일경 신고혈압과 동반된 전신 경련이 5분간 있어 뇌 자기 공명 영상을 촬영하였으며, 가역성 후백질 뇌병증 증후군의 양상을 보여 항 경련제 투여를 시작하였다. 이후 지속되는 혈소판 감소증 및 발열은 고용량 스테로이드 치료를 진행한 후 호전되었으나, 급성 신부전 및 단백뇨가 지속되어 신장 조직 검사를 진행하였으며, 검사 결과상 혈전성 미세혈관병증의 소견을 보였다. 이와 같이 조직검사상에서는 응고성 미세혈관병증을 보이나 전형적인 응고성 미세혈관병증의 혈액학적인 진단 기준이 충족되지 않는 비특이적 형태의 응고성 혈관병증의 효과적인 진단을 위하여 보체 기전이나 ADAMTS 13와 같은 유전자 범위의 보다 활발한 연구를 통한 효과적인 진단 기준의 마련이 되어야 할 것으로 보인다.

아파트의 친환경적 실내마감재에 대한 인테리어 디자이너와 주부의 인식 및 선호 비교

오지영,김미희,Oh, Ji-Young,Kim, Mi-Hee 한국주거학회 2009 한국주거학회 논문집 Vol.20 No.1

As a response to the recent increase in the Interest in environment friendly interior finishing materials, the purpose of this study is to compare the awareness of environment friendly interior finishing materials between interior designers and housewives, as representatives of two different consumer groups, and to examine how the preferences between them differ. The study participant group for this research consisted of 80 interior designers working in Gwangju, and 166 housewives who were residents of a number of apartments in Gwangju. Self administered questionnaires were provided to the participants and were then collected. Unpaired t-tests and $x^2$ tests were used to compare the prevalence of epidemiological factors and the variables that revealthe awareness and the preference between the two groups. While it was expected that both groups would source information using the internet, the housewives group showed a tendency to also seek advice from others in the selection of environment friendly interior finishing materials. Interior-designers considered the high price and the lack of diverse products as the most serious problems involved in selecting environment friendly interior finishing materials. Interior-designers chose design, color and long-term use, and the method of maintenance as standards by which to choose interior materials in general, while the housewives considered 'environment friendly' as the most important standard. Both groups however favored environment friendly materials. There was no difference between the two groups in terms of their belief in the need to trust a well known brand name and in the importance of a Green-label placed on interior finishing materials such as wallpaper, paint and laminate flooring.

Renal Manifestations and Imaging Studies of Kawasaki Disease

오지영,박세진,김선정,장광천,김유리아,신재일,김기혁,Oh, Ji Young,Park, Se Jin,Kim, Sun Jung,Jang, Gwang-Cheon,Kim, Uria,Shin, Jae Il,Kim, Kee Hyuck Korean Society of Pediatric Nephrology 2013 Childhood kidney diseases Vol.17 No.2

목적: 본 연구는 가와사키 질환의 신장 침범에 대하여 비교적 덜 침습적이며, 특이도와 민감도가 높은 검사인 Technetium-99m dimercaptosuccinic acid scintigraphy (DMSA renal SPECT)을 통하여 밝혀보고자 한다. 방법: 2011년 3월부터 10월까지 국민건강보험 일산병원에서 가와사키로 진단된 15명의 환아들을 대상으로 진행하였다. 15명의 환아 모두 가와사키의 급성기에 DMSA renal SPECT를 시행하였다. 또한 신장 세뇨관 손상 지표인 요중 ${\beta}2$-microglobulin (${\beta}2$-MG)을 측정하여 이를 통한 가와사키 환아에서 신장 손상의 조기 진단 가능 여부를 연구해보았다. 결과: 환아 15명 모두의 신기능 검사는 정상이었다. 소변 검사상 현미경적 혈뇨와 농뇨가 각각 13%, 33%에서 관찰되었다. 요중 ${\beta}2$-MG는 46%에서 증가된 소견을 보였다. 또한 환아들을 요중 ${\beta}2$MG를 기준으로 증가되어 있는 군과 증가되지 않은 군으로 나누어 비교, 분석해 보았으며, 두군간에 임상 증상, 임상 검사, 초음파 검사 및 심초음파 검사에서 유의한 차이를 보이지 않았다. 모든 환아에서 DMSA renal SPECT는 정상 소견을 보였다. 결론: 본 연구에서 가와사키 질환의 신장 침범은 경한 소변 검사 이상 및 일부 환아에서의 요중 ${\beta}2$-MG의 상승 소견을 보였으며, DMSA renal SPECT에서 관찰될 정도의 신장 침범은 보이지 않았다. Purpose: The aim of this study was to verify renal inflammation following Kawasaki disease (KD) using single photon emission computed tomography along with Technetium-99m dimercaptosuccinic acid scintigraphy (DMSA renal SPECT). Methods: From March 2011 to October 2011, 15 patients diagnosed with KD at the National Health Insurance System Ilsan Hospital were enrolled in the study. All patients underwent DMSA renal SPECT to evaluate renal involvement during the acute phase of KD. Urine ${\beta}2$-microglobulin (${\beta}2$-MG), a marker of renal proximal tubular dysfunction, was also measured to assess renal damage. Results: All 15 patients had normal renal function test results. However, microscopic hematuria and pyuria were observed in 13% and 33% of the patients, respectively. Moreover, urine ${\beta}2$-MG was elevated in 46% of the patients. In addition, patients were divided into two groups based on ${\beta}2$-MG level: those with an increased ${\beta}2$-MG level, and those with a normal ${\beta}2$-MG level. No significant differences were found between these two groups in clinical characteristics, laboratory, sonography, and echocardiography findings. All patients' DMSA renal SPECT scans were normal. Conclusion: Our study showed that mild abnormalities in the urinalysis and elevated urine ${\beta}2$-MG were the only findings of renal involvement in KD. However, no aggressive renal manifestations were detected on DMSA renal SPECT.

대학생의 성격 유형에 따른 헤어 스타일과 의복 이미지 선호 연구

오지영 ( Ji Young Oh ),김영철 ( Young Chul Kim ) 服飾文化學會 2006 服飾文化硏究 Vol.14 No.4

신고전주의 뮤지엄의 공간구조분석과 전시영역특성에 관한 연구

오지영(Oh, Ji-Young),박혜경(Park, Hey-Kyung),김석태(Kim, Seok-Tae) 한국실내디자인학회 2011 한국실내디자인학회논문집 Vol.20 No.3

This study analyzed characteristics of space configuration and exhibition contents in the Neo-classism style museum while carrying out space syntax and visibility graph analysis. Therefore, this research has the purpose to survey the status of existing museum analyze their visual perception space structural characteristics and ultimately utilize their characteristics as basic data in planning out and designing space. As for the research scope, the research selected as research subject 4 Neo-classism style museum in Europe and US that composite set of room to room type and having major space. Research method is that the research analyzed the exhibition space of 4 art museums by using depth-map program which can analyze space with visual graph analysis function and analyzed the visibility among unit areas by each art museum integration and exhibition contents composition. In such analysis method, the research was able to quantitatively analyze the visual characteristics of exhibition space that induce and adjusts the motion of audience. Visual perception quantitive analysis as in this research will enhance exhibition design by considering the correlation between audience and exhibited items when planning out art museum space to be established later on. Therefore, wien museum integration degree are high because of same openings direction and major space, Also another museums major space integrations are high level degree, and Exhibition area is set of high integration area. So, visitors can perceive exhibition contents easily.

성격유형이 의복이미지와 헤어스타일에 미치는 영향

오지영(Oh Ji-Young) 한국인체미용예술학회 2005 한국인체미용예술학회지 Vol.6 No.1

  The purpose of this study was to determine if personality types affect hair style and clothing image. Personality types was applied using Myers-Briggs type Indicator(MBTI). Subjects were 101 students at Keimyung university in Daegu, Korea.<BR>  The results of the study were as follows; 1) Results revealed only one significant difference between hair style and personality type. Sensing type and intuition type had significant difference in hair wave. 2) There are several significant differences between clothing image and personality type. Extroversion type was significantly evaluated in avantgarde clothing image more than introversion type. Intuition type was significantly evaluated in exotic and avantgarde clothing image more than sensing type. Feeling type was significantly evaluated in active clothing image more than thinking type. Judging type was significantly evaluated in elegance clothing image more than perceiving type.

3차원 모델을 이용한 한-일 수화 영상통신 시스템의 구현

吳芝英(Ji-Young Oh),金商雲(Sang-Woon Kim),靑木 由直(Yoshinao Aoki) 대한전자공학회 1998 대한전자공학회 학술대회 Vol.1998 No.6

19세기 중국의 반봉건적 여성의식과 시각적 표현

오지영(Oh Ji-young) 한국근현대미술사학회 2015 한국근현대미술사학 Vol.29 No.-

China in the 19th century was predicted to face an enormous transformation due to internal awakening of the traditional order and external shock caused by opening its ports. Amid the flow of these changes, new image of women was explored. The traditional custom that yoked women was harshly criticized, and the society experienced revolutionary changes in discourse and representation of women in early 20th century. But these changes did not suddenly come in one fell swoop. In the meantime, changes in the concept and representation of women had been accumulated. Flowers in the Mirror(鏡花緣), a novel written by Li Ruzhen(李汝珍, 1763-1830) during the first half of 19th century, flatly reflected these changes. It is very significant in that it originated the huge change in the 20th century by resolutely challenging the traditional concept of women and presenting an alternative image of women. Illustrations of Flowers in the Mirror(wood-block printed edition in 1832/ lithography edition in 1888) advocated physical liberation of women who were yoked by traditional footbindings, while suggesting strong image of women who improved their own lot by breaking away weak and passive image. Overcoming the concept of tradition that regarded talentless women as a virtue, they actively praised talents of women. On the other hand, the intention of the text was considerably faded and refracted by the artist due to the historical limitation of Chinese society in the 19th century. While the anti-feudalistic perception of women ruptured firm traditional courtesy and order, it was also denied by the society at the same time.Yet, illustrations of Flowers in the Mirror originally show that manoriented and patriarchal discourse and representation of women were changing at the turn of the 19th century. They symbolically reflect changes in the representation of women had originated from Chinese society itself before Western discourse on women was introduced by opening ports. And we can say that it was an important clue for revolutionary change in women’s representation in the forthcoming 20th century.

김치유래 Pichia속 효모가 생산하는 L-galactono-γ-lactone oxidase의 분리 정제 및 특성

오지영(Ji-Young Oh),한영숙(Young-Sook Han) 한국식품과학회 2003 한국식품과학회지 Vol.35 No.6

역사유물을 통한 지역 색채 아이덴티티 개발 연구

오지영(Ji-Young Oh),박혜경(Hey-Kyung Park) 한국색채학회 2013 한국색채학회 논문집 Vol.27 No.3

김해시는 금관가야의 옛 수도이며 이러한 사실을 입증하듯 많은 유물이 출토되었고 역사적 아이덴티티를 가지는 도시이다. 그동안 김해시의 정책과정 중에 `가야의 색` 이라는 이름하에 다양한 색채가 공공시설물 등에 적용 되어 왔으나 이는 주관적으로 사용되어 왔을 뿐 보다 객관화 된 색채기준을 가지고 적용하는데 있어서 혼란이 야기되어 왔다. 김해시가 가지는 역사적 지역아이덴티티를 확고히 확립하고 가야의 색을 사용하는데 있어서 혼란을 방지하기 위한 목적으로 김해시 색채가이드라인을 개발하는 것이 본 연구의 목적이다. 타 지역의 색채가이드라인을 비교, 분석한 결과 김해시의 색채가이드라인은 보다 정량적이고 객관화 된 데이터를 가져야 한다고 사료되었다. 이를 위하여 김해의 역사적 아이덴티티를 부각시킬 수 있는 가야유물을 분류화 하여 직접 측색하는 방법을 통해 색채가이드라인을 수립하였다. 총 6개의 유물을 측색하여 40개의 측색컬러 데이터를 얻을 수 있었으며 이 중 각 유물을 대표하는 대표색을 정하고, 대표색의 먼셀값을 중심으로 색상, 명도, 채도의 범위를 선정하여 색채가이드라인을 제안하였다. 또한 이 범위 내에서 색채팔레트를 개발하였으며, 공공시설물 이미지에 적용하여 시뮬레이션을 해보았다. 본 연구의 결과로 김해시에서 출토된 가야유물을 직접 측색한 결과 토기의 경우 Y, YR계열의 색채가 나타났고, 직접 측색이 불가하여 웹칼라 분석으로 측색한 청동솥과 판값옷의 경우 다소 다양한 종류의 색상계열이 나타났다. 또한, 각 유물을 대표하는 대표색채를 선정하고 이를 기준으로 색상, 명도, 채도의 범위를 제안하여 보다 유기적이고 통일성을 갖는 색채계획이 이루어질 수 있도록 가이드라인을 개발하였다. Gimhae is the former capital of the Geum-gwan Gaya to go as evidenced by the fact that many of these artifacts have been excavated from this historical identify with the city. Meanwhile, during the course of the policy of Gimhae `color of Gaya` in the name of a different color has been applied to public facilities. However, it came to be used as subjectively objectified as to apply the color with standard has been confusing. Gimhae firmly establish the identity and go with a local in the use of color to avoid confusion with the aim to develop guidelines Gimhae color is the purpose of this study. Compared to other regions, the color of the guidelines the results of analysis to establish guidelines in color with a distinctive way Gimhae were established. And in order to obtain quantitative data, we objectify classification relics and directly to measure through using spectrophotomete. The remains of six 40 colorimetry color data could be obtained. And artifacts that represent each color have chosen as a representative, and suggest the range of the color hue, brightness and saturation centered on the representative color. Within this range, the color palette was develop, and tried to apply to the public facilities as the image. As a result of this study was excavated in Gimhae Gaya earthenware artifacts, the result of direct lateral Y, YR series of color appeared. And this cannot direct colorimetric analysis colorimetric color one cheongdongsot the web and in the case of pangapot series was a little different kind of color.