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Koebner 현상에 의해 선상태선의 임상 양상을 보인 광택태선
송영찬 ( Young Chan Song ),고종현 ( Jong Hyun Ko ),오병호 ( Byung Ho Oh ),이양원 ( Yang Won Lee ),최용범 ( Yong Beom Choe ),안규중 ( Kyu Joong Ahn ),송계용 ( Kye Yong Song ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.11
Lichen nitidus is an uncommon, asymptomatic cutaneous shiny papular eruption and it can rarely show Koebner`s phenomenon, which may clinically resemble lichen striatus. It is known that for such cases, the clinicopathological correlation is the most important factor for making the diagnosis and immunohistochemical staining for CD4, CD8 and CD68 can be helpful to differentiate these two diseases. We experienced a case of Koebner phenomenon, which clinically mimicked lichen striatus, in a patient suffering with lichen nitidus. (Korean J Dermatol 2008; 46(11): 1517∼1520)
송영찬 ( Young Chan Song ),오병호 ( Byung Ho Oh ),이양원 ( Yang Won Lee ),최용범 ( Yong Beom Choe ),안규중 ( Kyu Joong Ahn ),송계용 ( Kye Yong Song ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.1
Cutaneous leiomyoma is a rare benign tumor that originates from the smooth muscles derived from arrector pili muscles, the media of dermal blood vessels and the dartos muscle of the scrotum, vulva or nipples. Piloleiomyomas usually occur in the second to third decades of life with an equal incidence in men and women. They can be solitary, but multiple lesions are seen in 80% of these patients. Although multiple leiomyomas are often grouped, unilateral zosteriform pilar leiomyoma is rare. We report here on a rare case of grouped piloleiomyomas that presented as a zosteriform pattern on the right trunk of a 59-year-old woman. (Korean J Dermatol 2009;47(1):59~62)
Doxorubicin유발 심장독성에 미치는 L-Carnitine의 효과
김형춘,송계용,전구석,허인회,Kim, Hyoung-Chun,Song, Ke-Yong,Jeon, Ku-Seok,Huh, In-Hoi 대한약학회 1988 약학회지 Vol.32 No.4
This study was undertaken to elucidate the role of L-carnitine on cardiotoxicity induced by doxorubicin in mice. We designed to investigate both lipoperoxidation and histopathology in experimental group. The results obtained from prior with concurrent treatment of L-carnitine showed as follows; 1) Combination of L-carnitine showed significant inhibition of lipoperoxide in liver than heart. 2) By means of electron microscopy, we obtained histological evidence that doxorubicin-induced cardiomyopathy, is prevented by L-carnitine.
조광현,송계용,조미경,이유신,함의근 ( Kwang Hyun cho,Kye Yong Song,Mi Kyung Cho,Yoo Shin Lee,Eui Keun Ham ) 대한피부과학회 1988 大韓皮膚科學會誌 Vol.26 No.3
A histopathological study of erythema nodosum-like lesions in Behcet's disease was performed on 55 patients with incomplete and suspect types of Behcet's disease. Relatively common characteristics in histopathology of erythema nodosum-like lesions could be found in the patients with incomplete type of Behcet's disease. The histopathologic findings of erythema nodosum-like lesions in 21 patients with incomplete type of Behcet's disease were as follows : l. A moderate lymphocytic infiltration was found around the blood vessels and the sweat glands in the dermis. In the subcutaneous tissue, besides lymphohistiocytic infiltration, neutrophils were present in significant number in 9 cases (42.9%) 2. Vasculitis of small vessels was found within the periphery of fat lobules in 7 cases (81.0%), Five cases (23.8%) also showed thrombophlebitis. Seven cases (33.3%) showed histiocytic granuloma formation within the fat lobules. Microabscess formation in the subcutaneous tissue was seen in 5 cases (23.8 %), but it was not certain whether this was the charateristic feature.
피부질환에 상피세포내 Transglutaminase E 변동에 관한 면역조직화학적 관찰
조윤화,송계용,노병인,박상철 ( Yoon Whoa Cho,Kye Yong Song,Byung In Ro,Sang Chul Park ) 대한피부과학회 1991 大韓皮膚科學會誌 Vol.29 No.6
N/A The εN-(?-L-glutamyl)-L-lysine cross-links in cornified envelope of the stratum corneum are formed by specific enzymes termed transglutaminase(TG). TG are calcium dependent enzymes that catalyse an acyl transfer reaction. Among them transglutaminase E(TGE) type is distributed in the granular layer and is also known as termiral differentiation marker of keratinocyte. This study was done to observe the distrubution pattern of TGE in the epidermis of various skin diseases by immunohistochemical PAP method using antihuman TGE antibody. Results were as follows : 1. Staining reaction for the TGE is strongest in the granular layer of the normal epidermis-TGE positive keratinocytes numbers are increased in the thickened granular and upper stratum spinosum in the dermatoses accompanying acanthosis with orthohyperkeratosis wherease decreased of absent in the dermatoses accompanying ?canthosis with parakeratosis. Atrophic epidermis shows decreased TGE staining reaction. 2. Staining reaction for the TGE is negative or weakly positive in dysplastic or atypical keratinocytes. Nonkeratinizing squamous cell carcinoma cells are negatively stained whereas keratinizing cells are positively stained according to the degree of keratinizing. Basal cells, whether in benign or malignant conditions were very weakly or negatively stained. Therefore, immunohistochemical staining for the TGE reveals the most abundant distribution in the granular layer and upper spinous layer in normal conditions and shows variation in its distribution with processes related to acanthosis, cornification and its terminal differentiation of keratinocytes.
임형빈,김경남,송계용,이성복,Hyung Bin Lim,Kyoung Nam Kim,Gae Young Song,Sung Bok Lee 대한안과학회 2014 대한안과학회지 Vol.55 No.3
Purpose: To report a case involving an eyelid mass that was diagnosed as apocrine carcinoma. Case summary: A 52-year-old man visited our hospital with a recurrent mass on his right upper eyelid, which had developed 4 years prior. Initially, he received laser therapy at a dermatologic clinic to remove the mass. Two years later, the mass recurred and was excised at another clinic. At the time the patient visited our institution, the lesion had developed into multiple erythematous nodules at the margin of the right upper eyelid. The results of excisional biopsy performed under local anesthesia revealed hidradenoma papilliferum. One month after excision, recurred multiple elevated nodules were found at the margin of the excision, and thus total excision of the mass and reconstruction of the upper eyelid was performed. Biopsy confirmed that the mass was apocrine adenocarcinoma. Five months have passed since the excision and no evidence of recurrence has been observed. Conclusions: Apocrine adenocarcinoma is a malignant tumor of the sweat gland and is rarely found on the eyelid. Apocrine adenocarcinoma should be considered in the differential diagnosis of recurrent eyelid mass at the eyelid margin. J Korean Ophthalmol Soc 2014;55(3):432-436
전태진,김명남,송계용,노병인 ( Tae Jin Chun,Myeung Nam Kim,Kye Yong Song,Byung In Ro ) 대한피부과학회 1991 대한피부과학회지 Vol.29 No.5
Verrucous hemangioma is a variant of a capillary, carvernous, or mixed hemangioma which undergoes a reactive proliferative epidermal change. We report two cases which showed clinical and histopathologic findings of verrucous hemangioma. In both cases, reddish hemangiomatous lesions were present since birth and were verrucous crusty lesions of the right lower extremity. Skin biopsy revealed hyperkeratosis, acanthosis, and papilomatosis of the epidermis and proliferation and dilatation of capillaries in the upper dermis in addition to the capillary hemangioma in the deep dermis and subcutis.