急·慢性腎炎의 鑑別要領

朴?炫 藥業新聞社 1984 (月刊) 醫藥情報 Vol.1984 No.3

복수 재발한 급성림프구성 백혈병 1예에서중추신경계 질환 치료 방법

지종현,홍유라,박성인,박재선 고신대학교(의대) 고신대학교 의과대학 학술지 2003 고신대학교 의과대학 학술지 Vol.18 No.1

Methotrexate (MTX) is one of the most widely used drugs for the treatment of childhood acute lymphoblastic leukemia (ALL) and is commonly given in high doses. Systemic chemotherapy, triple intrathecal (TIT) treatment and craniospinal radiation was given to a child with meningeal involvement at presentation. But meningeal leukemia was recurred 3 months later, which was remissioned secondly by TIT chemotherapy. One year later from first diagnosis, second meningeal relapse was presented with immature cell count of 12/mm3 in CSF and a large intracerebral mass on brain CT. A high-dose methotrexate (HDMTX) had been challenged in dose of 2.8-5.0 g/m2 with TIT chemotherapy. In HDMTX schedule, leucovorin (LCV) was administered orally (12 times, 15 mg/m2 every 6 hours), 24 hours later from the start. Intracerebral mass disappeared two weeks later (with 2 weekly administration of HDMTX) and the third remission was lasted for 80 months. Third isolated meningeal relapse, which occurred on July 28, 2000, remissioned again with HDMTX plus TIT chemotherapy, but he died of fungal sepsis and interstitial pneumonia. Although the patient died of treatment related disease, systemic intravenous HDMTX and TIT therapy appears to provide another option in the treatment of relapsed meningeal leukemia after craniospinal irradiation.

수열에너지 입지 선정을 위한 계층화분석법의 적용

안주현,박수완,오창현 대한상하수도학회 2024 상하수도학회지 Vol.38 No.2

In this study, an evaluation system that can be used to evaluate the feasibility of developing and supplying hydrothermal energy for the operation of large-scale complex facilities was developed. To this end, this study derived factors to be considered when selecting a location for the use of hydrothermal energy using raw water from multi-purpose dams and regional water supply systems through literature survey and expert interviews. The evaluation indicators derived from this study are divided into four sectors: hydrothermal energy utilization factors, location factors, planning factors, and disaster safety factors, and are composed of 10 mid-level indicators and 34 detailed planning indicators. The relative importance of all factors was derived using the Analytic Hierarchy Process (AHP) technique, and the developed evaluation indicators and relative importance were applied to four multi-purpose dam regions in the country. As a result, it was found that in the development and use of hydrothermal energy utilizing regional raw water supply line the urban planning conditions of the supply site can have a greater impact on the location selection results than the hydrothermal energy development itself. Due to the characteristics of the evaluation indicators developed in this study and their nature as comprehensive indicators, it is believed that the results should be applied to determine the overall adequacy of site selection in the early stages of hydrothermal energy development. In the future, it is believed that it will be necessary to analyze the problems in supplying and operating hydrothermal energy using raw water from multi-purpose dams and regional water resources. Based on the analysis the evaluation system developed in this study is expected to be improved and supplemented.

한라산 천연보호구역 내 5.16 도로 인근 산림토양의 분류

박원표(Won-Pyo Park),장진현(Jin-Hyeon Jang),고석형(Suk-Hyung Ko),현해남(Hae-Nam Hyun),송관철(Kwan-Cheol Song) 한국토양비료학회 2022 한국토양비료학회 학술발표회 초록집 Vol.2022 No.10

Bubble Tank를 이용한 포름알데히드 흡수반응특성 연구

박영성,경대현 한국냄새환경학회 2009 실내환경 및 냄새 학회지 Vol.8 No.4

Absorption characteristics of formaldehyde (one of odors) were investigated using a bubble tank. The capacity of reaction tank made of acrylic is I liter and the experiment was carried out as semi-batch mode (for given absorbent packing, formaldehyde was fed continuously with flow rate of 2 liter/min). As operating variables of experiment, concentration of formaldehyde (400~800 ppm), absorption temperature (25~45℃), and packing volume of absorbent (100~300 mL) were used. The experimental results showed that the removal efficiency of formaldehyde decreased from 5 to 10% as the concentration of formaldehyde and the absorption temperature increased from 400 to 800 ppm, and from 5 to 10%, respectively, while it increased with the increase of the packing volume of absorbent.

요양보호사 양성교육에 대한 만족도 조사 : 교육기관 유형별 요양보호사의 만족도 차이 분석을 중심으로

박정임,주재현 명지대학교 사회과학연구소 2009 사회과학논총 Vol.29 No.-

2008년 7월부터 시행된 노인장기요양보험제도의 성패를 좌우하는 주요 요인 중 하나는 유능한 요양보호사의 양성이라 할 것이다. 이러한 요양보호사의 양성을 위한 교육내용 점검의 일환으로 본 연구는 요양보호사를 대상으로 양성기관의 교육내용에 대한 만족도 조사를 실시하며, 현 양성과정의 문제점을 분석하고 그에 따른 대안을 모색하고자 하였다. 양천구에서 실시한 설문조사 결과 교육내용 특히 현장실습과 실기에 대한 만족도가 상대적으로 낮았으며 이는 개인이 설립운영중인 교육기관에서 두드러졌다. 따라서 기관 운영주체별 펀차를 감소시키기 위해서는 교육기관의 설립과 운영에 대한 정부의 제도적 지침을 더욱 강화하여야 할 것이다. 또한 현재 교육수료 여부에 따라 부여되는 자격증을, 검정을 거쳐 부여해야 할 것이며, 교육시간 증대와 더불어 교육과정에 있어 현장중심형의 전문가 양성체계를 확립해야 할 것이다.

딥러닝 기반 보행자 위험 지역 침입 단계별 인식 방법

박성실,조익현,박민성,임상일,박영기 한국ITS학회 2019 한국ITS학회 학술대회 Vol.2019 No.11

국소 진행성 유방암 환자에서 선행 항암화학요법의 치료결과

배선현,박원,허승재,최두호,남희림,양정현,남석진,이정언,임영혁,안진석,박연희 대한방사선종양학회 2010 Radiation Oncology Journal Vol.28 No.2

Purpose: To evaluate the result of neoadjuvant chemotherapy, surgery, and radiation therapy in locally advanced breast cancer as well as analyze the prognostic factors affecting survival. Materials and Methods: One hundred fifty-nine patients with breast cancer were treated by neoadjuvant chemotherapy between April 1995 and November 2006 at the Samsung Medical Center. Among these patients, we retrospectively reviewed 105 patients treated with neoadjuvant chemotherapy followed by surgery and radiation therapy for a cure with an initial tumor size >5 cm or clinically positive lymph nodes. All patients received anthracycline based chemotherapy except for 2 patients. According to clinical tumor stage, 3 patients (3%) were cT1, 26 (25%) were cT2, 39 (37%) were T3 and 37 (35%) were T4. Initially, 98 patients (93%) showed axillary lymph node metastasis. The follow-up periods ranged from 7∼142 months (median, 41 months) after the beginning of neoadjuvant chemotherapy. Results: Locoregional failure free survival rate and distant metastasis free survival rate at 5 years were 82.1% and 69.9%, respectively. Disease free survival rate and overall survival rate at 5 years were 66.1% and 77.1%, respectively. The results of a univariate analysis indicate that clinical tumor stage, pathologic tumor stage, pathologic nodal stage and pathologic TNM stage were statistically significant factors for disease free survival rate and overall survival rate. Whereas, a multivariate analysis indicated that only hormone therapy was a statistically significant factor for survival. Conclusion: The current study results were comparable to other published studies for neoadjuvant chemotherapy for breast cancer. Hormone therapy was a statistically significant prognostic factor. The patients with early clinical or pathologic stage had a tendency to improve their survival rate. 목 적: 국소 진행성 유방암으로 선행 항암화학요법 후 수술과 방사선치료를 시행한 환자를 대상으로 치료 결과와 예후에 영향을 미치는 인자를 알아보고자 하였다. 대상 및 방법: 1995년 4월부터 2006년 11월까지 삼성서울병원에서 유방암으로 선행 항암화학요법을 받은 환자는 총 159명이었다. 이중에서 진단 당시 종양의 크기가 5.0 cm를 초과하거나 액와림프절 전이가 의심된 유방암 환자로 항암화학요법 후 근치적 수술을 시행하고 방사선치료가 시행된 105명을 대상으로 하였다. 선행 항암화학요법은 2명을 제외한 모든 환자에서 anthracycline을 기반으로 하는 복합항암요법을 사용하였다. 치료 전 임상적 병기는 T1 3명(3%), T2 26명(25%), T3 39명(37%), T4 37명(35%)이었고 액와림프절 전이가 의심되는 사람이 98명(93%)이었다. 선행 항암화학요법을 시작한 날을 기준으로 추적 조사하였고 중앙추적조사기간은 41개월(7∼142개월)이었다. 결 과: 전체 환자의 5년 국소제어율은 82.1%, 원격전이제어율은 69.9%, 무병생존율은 66.1%, 전체생존율은 77.1%이었다. 무병생존율과 전체생존율에 영향을 미치는 인자를 알아보기 위해 단변량분석을 시행하였을 때 임상적 원발병소 병기, 병리학적 원발병소 병기, 병리학적 림프절 병기 그리고 병리학적 TNM 병기가 공통적으로 통계적으로 유의한 인자들이었다. 다변량 분석을 시행하였을 때 호르몬치료 유무만 생존율과 연관된 의미 있는 인자였다. 결 론: 본 연구를 통하여 삼성서울병원에서 국소 진행성 유방암으로 선행 항암화학요법이 시행된 환자의 치료 성적이 지금까지 보고된 다른 선행 항암화학요법 치료 결과와 비교할 때 비슷하거나 나은 결과를 보여주었다. 또한, 호르몬치료를 시행한 경우에만 생존율이 의미 있게 좋았고 임상적 병기나 병리학적 병기가 낮은 경우 생존율이 좋은 경향을 보였다.

복수 재발한 급성림프구성 백혈병 1예에서 중추신경계 질환 치료 방법

지종현,홍유라,박성인,박재선 고신대학교 의학부 2003 高神大學校 醫學部 論文集 Vol.18 No.1

Methotrexate (MTX) is one of the most widely used drugs for the treatment of childhood acute lymphoblastic leukemia (ALL) and is commonly given in high doses. Systemic chemotherapy, triple intrathecal (TIT) treatment and craniospinal radiation was given to a child with meningeal involvement at presentation. But meningeal leukemia was recurred 3 months later, which was remissioned secondly by TIT chemotherapy. One year later from first diagnosis, second meningeal relapse was presented with immature cell count of 12/㎣ in CSF and a large intracerebral mass on brain CT. A high-does methotrexate (HDMTX) had been challenged in dose of 2.8-5.0 g/㎡ with TIT chemotherapy. In HDMTX schedule, leucovorin (LCV) was administered orally (12 times, 15 ㎎/㎡ every 6 hours), 24 hours later from the start. Intracerebral mass disappeared two weeks later (with 2 weekly administration of HDMTX) and the third remission was lasted for 80 months. Third isolated meningeal relapse, which occurred on July 28, 2000, remissioned again with HDMTX plus TIT chemotherapy, but he died of fungal sepsis and interstitial pneumonia. Although the patient died of treatment related disease, systemic intravenous HDMTX and TIT therapy appears to provide another option in the treatment of relapsed meningeal leukemia after craniospinal irradiation.

황토-사전적 해석을 넘어서는 마당굿으로…

박영웅,박재화,박찬중,양준호,오진현,이청화,장재훈 문예운동사 1980 문예운동 Vol.- No.28