교애사물탕이 랫드의 모체와 태자에 미치는 영향에 대한 연구

김창석,박해모,신헌태,이장우,김경태,김판기,이선동,한상백,한용주,Kim, Chang-Seok,Park, Hae-Mo,Shin, Hun-Tae,Lee, Jang-Woo,Kim, Kyung-Tae,Kim, Pan-Gyi,Lee, Sun-Dong,Han, Sang-Baek,Hahn, Yong-Joo 대한예방한의학회 2006 대한예방한의학회지 Vol.10 No.2

This study was undertaken to investigate the effects of Gyoaesamultang in pregnant rats and their fetuses. Female Sprague-Dawley rats were orally administered with the Gyoaesamultang at dose of 5mg/kg/day for 20 days. Pregnant rats were sacrificed at 20th day of gestation, and observed internal and reproductive organs. Approximately, live fetuses in the 20th day of gestation were randomly selected and fixed in 95% ethanol. To observe skeletal malformations, fetuses were stained with alcian blue and alizarin red S. Maternal body weight of Gyoaesamultang treated group has a tendency to increase compared to that of control group. There were no significant difference in internal and reproductive organs. There were no significant changes between two groups in blood chemistry and hematological values. There were no significant changes in number of corpus luteum, implantation, live fetuses and implantation rate, delivery rate, late resorption rate and sex ratio. But Gyoaesamultang administered group showed lower early resorption rate than the control group. Neonatal body weight and number of fetus of Gyoaesamultang group were increased to that of control group. The fetuses of dams treated with Gyoaesamultang didn't showed external malformation. Vertebral and sternal variations were observed in Gyoaesamultang group but, compared to the control, those variations were insignificant. The number of ribs, cervical, thoracic, and lumber were normal. The number of sacral and caudal vertebrae were increased. Fetuses treated with Gyoaesamultang showed significant difference in the number of caudal vertebra(P<0.01). From these results, it can be concluded that Gyoaesamultang showed no toxicity effects on maternal body weight, early resorption rate, and number of live fetuses. There were no significant changes in organ weight, hematological data, reproductive organs. Although skeletal variations were showed in vertebrate and sternum, Gyoaesamultang were shown insignificant changes in bone malformation.

고혈압의 한약 치료에 대한 연구동향 분석

김창석,김영은,김철,김진현,예상준,송미영,Kim, Chang-Seok,Kim, Young-Eun,Kim, Chul,Kim, Jin-Hyun,Yea, Sang-Jun,Song, Mi-Young 대한예방한의학회 2011 대한예방한의학회지 Vol.15 No.3

Objectives : This study aims to provide the fundamental information for future researches on combined medications of the oriental-western medicines or development of new Oriental medicine for hypertension. Methods : Every article related to hypertension was initially searched at journal web site, 'OASIS' and we finally analyzed 118 papers according to study types, kinds of herbal medicine, frequencies of herbal medicine, and results of researches. Results : Most studies were experiment researches which were composed of in vivo or in vitro. The formulas divided into 41 single and 99 complex prescriptions and total 218 medicinal materials were used in complex ones. The major effects of single prescriptions were decrease of the control of ACE activity and ANP concentration, while the effects of complex ones were various such as decrease of aldosteron concentration, decrease of epinephrine concentration, decrease of the heart rate, and decrease of dopamine concentration. Conclusions : More clinical studies based on scientific evidences should be done and the outcomes of this pilot study will contribute to development of Oriental medicines as substitute or combination for the western-hypertension remedies.

논에서 잡초발생패턴 조사

김창석,이정란,김경훈,김미선,박찬애,이인용,Kim, Chang-Seok,Lee, Jeong-Ran,Kim, Kyung-Hoon,Kim, Mi-Seon,Park, Chan-Ea,Lee, In-Yong 한국잡초학회한국잔디학회 2012 Weed&Turfgrass Science Vol.32 No.1

파장훑음 레이저의 개발

김창석,이휘돈,Kim, Chang-Seok,Lee, Hwi-Don 한국광학회 2017 광학과 기술 Vol.21 No.1

N-Cyanoethylazacrown의 합성과 그의 전이 금속 착물 형성 상수

김창석,김동원,정용순,최기영,홍춘표,Kim, Chang Suk,Kim, Dong Won,Chung, Yong Soon,Choi, Ki Young,Hong, Choon Pyo 대한화학회 2000 대한화학회지 Vol.44 No.3

관계형 데이터 모델 기반 군사용 데이터베이스의 XML 데이터베이스로의 변환

김창석,김응수,Kim, Chang-Seok,Kim, Eong-Su 대전대학교 군사연구원 2003 군사학연구 Vol.1 No.-

AS Extensible Markup Language(XML) is emerging as the data format of the Internet era, there are increasing needs to efficiently transform between database and XML documents. In this paper, we propose a schema transformation method from relational database to XML database. To transform the schema, we represent input schema as Entity-Relationship diagram. Entity-Relationship model translator scans the input Entity-Relationship diagram using BFS (breadth First Search) and translates the diagram into hierarchical structure model. The XML Schema generator produces XML Scema code using the transformed hierarchical structure model. The proposed method has a merit that having reusability facility of XML Schema property in comparison with existing researches.

ER2XML :개체-관계 모델을 기반으로한 XML Schema 생성기의 구현

김창석,손동철,Kim Chang Suk,Son Dong-Cheul 한국정보처리학회 2005 정보처리학회논문지D Vol.12 No.1

XML이 웹 상에서 문서 교환의 표준으로 자리잡고 있으며 피 수요가 나날이 증가하고 있다. 그에 따라 in 데이터나 문서 구조를 모델링하는 XML Schema(W3C XML Schema Spec) 또한 수요가 증가하고 있다. 그러나 XML Schema는 다양한 자료형과 풍부한 표현력을 제공하지만 그 복잡성으로 인해 모델링하기가 어려운 단점이 있다. 본 논문에서는 관계형 데이터베이스 설계의 기본적인 도구인 개체-관계 모델을 이용하여 XML Schema를 간단하게 생성하는 방법을 제시한다. 개체-관계 모델과 변환될 XML Schema의 구조는 서로 일대일로 매핑되지 않아 직접 변환할 수는 없다. 그래서 몇 가지 알고리즘을 이용하여 개체-관계 모델을 계층적 구조모델로 변환을 한다. 이렇게 변환된 계층적 구조 모델을 이용하여 최종적으로 XML Schema를 생성한다. 기존의 XML Schema 생성 방법은 개체 간의 속성이 상위 혹은 하위로 이동하면서 최초 설계시의 개체가 사라지므로 XML Schema의 중요한 특성인 재사용성을 이용할 수 없다는 단점을 가진다. 석기서 제시한 알고리즘은 XML Schema의 중요한 특성들인 재사용성, 전역 및 지역 기능 등을 가진 문서를 생성한다는 것이다. The XML is emerging as standard language for data exchange on the Web. Therefore a demand of XML Schema(W3C MLL Schema Spec.) that verifies XML document becomes increasing. However, XML Schema has a weak point for design because of its complication despiteof various data and abundant expressiveness. This paper shows a simple way of design for XML Schema using a fundamental means for database design, the Entity-Relationship model. The conversion from the Entity-Relationship model to XML Schema can not be directly on account of discordance between the two models. So we present some algorithms to generate XML Schema from the Entity-Relationship model. The algorithms produce XML Schema codes using a hierarchical view representation. An important objective of this automatic generation is to preserve XML Schema's characteristics such as reusability, global and local ability, ability of expansion and various type changes.

집합주거단지의 근린주구계획

김창석,Kim, Chang-Seok 대한건축사협회 1991 建築士 Vol.1991 No.11

ZnO/rutile-$TiO_2$, ZnO, rutile-$TiO_2$, CdS를 이용한 Congo red의 광 촉매 분해반응

김창석,류해일,Kim, Chang Suk,Ryu, Hae-Ill 한국분석과학회 2001 분석과학 Vol.14 No.3

ZnO, CdS, rutile-$TiO_2$ 및 혼합 rutile-$TiO_2$/ZnO와 같은 여러 반도체를 이용하여 Congo Red를 광 촉매 분해시켰다. 연구 결과 ZnO, CdS, rutile-$TiO_2$ 중에서는 CdS의 광 촉매 효과가 제일 컸는데 이것은 CdS가 제일 작은 band gap 에너지를 가지고 있기 때문이었다. 또한 혼합 촉매에서는 ZnO의 함량이 rutile-$TiO_2$에 비하여 상대적으로 높을수록 분해 반응을 촉진하였다. 이것은 $Zn^{2+}$ 가수분해 생성물이 구조적으로 안정한 화합물인 rutile-$TiO_2$의 표면을 덮음으로서 자외선 흡수를 차단하기 때문에 라디칼 생성을 저해하기 때문이었다. Photocatalytic degradation of Congo red was performed using various semiconductors as ZnO, CdS, rutile-$TiO_2$ or mixed rutile-$TiO_2$/ZnO. The change of degradation of the dye was investigated by UV-visible spectrophotometric method. The photocatalytic action of CdS was greater than ZnO and rutile-$TiO_2$ in account of low band gap energy of CdS. The rate of photocatalytic degradation reaction increased drastically in according to increasing ratio of ZnO on mixed rutile-$TiO_2$/ZnO. These photocatalytic effect of rutile-$TiO_2$ was suppressed by more stable rutile-$TiO_2$, doping the hydrolysis product with $Zn^{2+}$ prior to calcination onto the rutile-$TiO_2$ surface.

서울시 동별 상류계층(파워엘리트) 주거 분포와 흡연과의 관련성에 대한 다수준분석

김창석,윤성철,김혜련,강영호,Kim, Chang-Seok,Yun, Sung-Cheol,Kim, Hye-Ryun,Khang, Young-Ho 대한예방의학회 2006 예방의학회지 Vol.39 No.1

Objectives: We examined whether the neighborhood socioeconomic position predicts the smoking rates after adjusting for individual socioeconomic position indicators. Methods: Data were obtained from the 2001 Seoul Health Indicators Survey. The neighborhood socioeconomic position was the residential distribution of the high class (power elites), as measured by the location quotients (LQ) for each administrative dong (district). A high LQ denotes a high neighborhood socioeconomic status. The individual socioeconomic position included education, occupation and income. Age-adjusted smoking rates according to the LQ level were computed with the direct method. The total number of subjects in this study (26,022 men and 28,007 women) was the reference. A multilevel logistic regression analysis was conducted with the individuals at the first level and the neighborhoods at the second level to estimate the odds ratios of smoking with 95% confidence intervals. Results: For men, the age-adjusted smoking rates increased with a decrease in the LQ. For women, the relationship between the age-adjusted smoking rate and the LQ was not clear. The odds of smoking for both genders were greater among those subjects with lower incomes and lower education. The manual occupational class had greater odds of smoking than the non-manual class for the males, while the odds ratio of smoking among females with a manual occupation tended to be lower than those females with a non-manual occupation. For the males, the LQ levels independently predicted smoking after adjustment for individual income. However, this relation between the LQ and smoking in males was explained by full adjustment for the individual socioeconomic position indicators (education, occupation and income). Conclusions: A low level of neighborhood socioeconomic position was associated with higher smoking rates among the men residing in Seoul. This association between the neighborhood socioeconomic position and smoking in men was explained by the individual socioeconomic position. Anti-smoking efforts to reduce geographical inequality in smoking should be directed at reducing the smoking rates between the individuals with different socioeconomic backgrounds in the metropolitan city of Seoul, South Korea.