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김주형,윤여안,이충만,유경화,Kim, Joo Hyoung,Youn, Yeoan,Lee, Choongman,Yoo, Kyung-Hwa 한국진공학회 2015 진공 이야기 Vol.2 No.1
A nanopore is a very small hole that can be used as single-molecule detector. The detection principle is based on monitoring the ionic current reduced by passage of a molecule through the nanopore as a voltage is applied across the nanopore. Here, we introduce biological nanopores and solid-state nanopores. Then, research and current trend about nanopore-based DNA biosensor and protein analysis are reviewed.
김주형 ( Joo Hyoung Kim ),전용철 ( Yong Cheol Jeon ),김태엽 ( Tae Yeob Kim ),은창수 ( Chang Soo Eun ),손주현 ( Joo Hyun Sohn ),한동수 ( Dong Soo Han ),장재정 ( Jae Jung Jang ),박용욱 ( Yong Wook Park ) 대한소화기학회 2008 대한소화기학회지 Vol.52 No.5
Intestinal tuberculosis is a common disease of extrapulmonary tuberculosis and should be differentiated from the inflammatory bowel diseases and malignancy such as Crohn`s disease, ulcerative colitis, amebic colitis, and colon cancer. Most frequently involved sites (75% of cases) are the terminal ileum and cecum. Other sites of involvement, in order of frequency, are ascending colon, jejunum, appendix, duodenum, stomach, esophagus, sigmoid colon, and rectum. Intestinal tuberculosis simultaneously involving the stomach and colon has been very rarely reported. Recently, we experienced a case of synchronous gastric and colonic ulcers with granulomatous inflammation. Although we did not find acid fast bacilli and the culture test was negative, empirical anti-tuberculosis therapy resulted in dramatic clinical and endoscopic improvement. We report a rare case of multifocal gastrointestinal tuberculosis with a review of literature. (Korean J Gastroenterol 2008;52:320-324)
효율적인 공간 질의 처리를 위한 Quadtree 클러스터링 알고리즘
김주형(Kim Joo-Hyoung),홍봉희(Hong Bong-Hee) 한국정보과학회 1998 정보과학회논문지(B) Vol.25 No.1
대용량의 데이타를 다루는 GIS에서 효과적인 질의 처리를 위해 공간 색인기법 및 클러스터링 방법이 연구되어 왔다. 특히 디스크 검색시간을 줄이기 위해서는 인접성, 연결성 등의 2차원 공간 데이타의 특성을 고려하여 1차원의 디스크에 저장하는 클러스터링 기법이 필요하다. 이 논문에서는 공간객체를 분할하지 않고 저장하는 확장된 Quad-tree에서의 클러스터링 기법을 제시한다. 인접한 공간 객체에 대한 구체적인 클러스터링 방법으로서 공간 객체의 무게중심과 참조점, 겹치는 영역을 토대로 한 클러스터링 방법을 제안한다. 또 이런 클러스터를 이용하여 질의 처리에 사용하는 방법을 제시하고, 이렇게 제시된 방법들을 실험을 통해 평가하여 각 방법들의 성능을 분석한다. There have been many works for developing spatial indexing and clustering methods for efficiently accessing a large volume of GIS data. To reduce I/O access time, It is necessary to support a clustering of logically related 2-dimensional data on the 1-dimensional disk. This paper presents a new clustering method on the extended Quad-tree which does not fragment any spatial object A number of clustering algorithms based on the gravity of geometry, the reference point of geometry, the overlap area are devised and evaluated. The result of performance evaluation of this methods is shown.
김주형(Joo Hyoung Kim) 한국언어치료학회 2016 言語治療硏究 Vol.25 No.4
Purpose: The core of reading comprehension is to determine the main idea of the text by integrating meanings of individual sentences. To find out the main ideas, we should concentrate on important information, not peripheral information which disturbs the integration process. The purpose of the present study was to examine the inference and inhibition skills of children with ADHD during reading. Methods: 16 children with ADHD and 16 typically developing children, all in grade 4 to 6, participated in the study. All participants were developmentally within a normal range of intelligence, vocabulary, word decoding, reading fluency, and reading comprehension. Thirty-six questions were provided to them. Each question consisted of two sentences and a target word. Participants read the two sentences and judged whether the target word was the main idea of the sentences. The questions were categorized into three conditions by the target words: main idea, peripheral word presented in the sentences, and unrelated word. Results: The ADHD children were not different from the typically developing children in the accuracy and reaction time when the target words were main ideas. However, the ADHD children’s accuracy was lowered and reading time was significantly slower than the typically developing children when the target words were peripheral ones. Conclusions: Participants with ADHD could discover the main idea when reading the text. They had difficulties in inhibiting peripheral informations. The ADHD children allocated resources not only to important information but also to peripheral information. The influence of inhibition deficit of ADHD on language processing was discussed.
간절제술전 간기능 예비력 검사로서의 Insulinogenic Index의 의의
김주형(Joo Hyoung Kim),김홍진(Hong Jin Kim),김상운(Sang Woon Kim),심민철(Min Chul Shim),권굉보(Koing Bo Kwun) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.2
N/A Major hepatic resection in cirrhotic or icteric patient has been known to frequently associate with postoperative hepatic insufficiency followed by systemic derangernent of metabolism and multiple organ failure. Hepatic insufficiency in cirrhotic liver is mainly caused by lower ATP generating potential of cirrhotic hepatocyte mitochondria. Portal blood containing insulin has the potential to enhance the ATP generating system in the hepatic rnitochondria. The number of in- sulin receptors and the affinity of these receptors in the cirrhotic liver are normally decreased. The important action of insulin on carbohydrate metabolisrn in the liver is considered to be the inhibition of gluconeogenesis and the enhancement of glycogenolysis, followed by the decrease in glucose output from the hepatic cells. Thus, the blood glucose and insulin response after oral glu- cose loading could be utilized as a guide for hepatic functional reserve. Surgical outcorne were studied retrospectively in 59 patients who underwent hepatic resections from July 1991 to August 1993. The insulinogenic index was calculated by a modifi- cation of Seltzer method for oral glucore tolerance test in the 59 patients. 18 of 59 patients in the hepatic resection group showed postoperative complications(30.5%) and insulinogenic index of these group was 0.40+0.03, 3 of whom experienced hepatic failure resulting in hospi- tal death(5.1%) and insulinogenic index of these group was 0.28+ 0.06. Mean insulinogenic index of the cirrhotic group was 0.65+0.07 in 27 patients. 12 of 27 patients who has liver cir- rhosis showed postoperative complication(44.4%) and insulinogenic index of these group was 0. 38+0.03, 2 patients showed hospital death(7.4%) and insulinogenic index of these group was 0. 35. In conclusion, from the viewpoint of hepatic mitochodrial energy metabolism, insulinogenic index in useful and reliable parameter of hepatic fuctional reserve, And further- more intraportal insulin administration has a beneficial effect on the post operative manage- ment and facilitates care of lower insulinogenic index patients, who are very high-risk candi- dates for major hepatic resection.(Korean J Gastroenterol 1994; 26: 265 272)
경북지역 환돈 유래 Salmonella Typhimurium의 약제내성 유전자 분석
김주형 ( Joo Hyung Kim ),김성국 ( Seong Guk Kim ),김선수 ( Seon Soo Kim ),김정화 ( Jeong Hwa Kim ),박세희 ( Sye Hee Park ),남기후 ( Ki Hu Nam ),김형배 ( Hyoung Bae Kim ) 한국동물위생학회 2013 韓國家畜衛生學會誌 Vol.36 No.2
This study was conducted to investigate antibiotic resistance among Salmonella Typhimurium isolates from diseased pigs in Gyeongbuk province during the period 1998∼2011. One hundred forty one isolates were tested for antibiotic resistance using the standard disk diffusion method and were examined for presence of resistance gene by PCR method. S. Typhimurium showed high drug resistance rates to tetracycline (95.7%), streptomycin (93.6%), ampicillin (86.5%), cephalothin (80.1%), gentamicin (79.4%), and trimethoprim/sulfamethoxazole (72.3%). Resistance gene, blaTEM, blaPSE1, tetA, tetB, tetG, sul1, sul2, aadA, strA, grm, and temA were detected among the antibiotic resistance isolates and temB, tetC, aadB gene were not detected. One hundred twenty one (89.6%) tetA, two (1.5%) tetB and one (0.7%) tetG gene were detected in the 135 tetracycline resistant isolates. Two (1.6%) temA gene were detected in one hundred twenty two ampicillin resistance isolates and temB was not detected.