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RISS 인기검색어
- 검색키워드
- 저자 : 이종원(Jong Won Lee) (검색결과 1,155 건)
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이종원,이미경,이형옥,이성계,도재호,김만욱 ( Jong Won Lee,Mi Kyung Lee,Hyung Ok Lee,Seong Kye Lee,Jae Ho Do Man Wook Kim ) 한국응용생명화학회 1997 Applied Biological Chemistry (Appl Biol Chem) Vol.40 No.5
The purpose of this study was to investigate the differences in proximate composition, free sugars, amino acids, fatty acids and Hunter color values between fresh and odorless garlic. The contents of crude fiber, crude fat and ash in odorless garlic were similar to those in fresh garlic. Sugars and crude protein decreased during manufacture of odorless garlic. Among the free sugars, sucrose, maltose and fructose decreased in odorless garlic, while the content of glucose increased. Total amino acid content decreased by about 30% in odorless garlic. Among the amino acids decreased arginine, isoleucine etc. The contents of linoleic acid, palmitic acid and oleic acid were higher than those of other fatty acids in fresh garlic and odorless garlic, but laruric acid was in little quantity. There were no significant differences in the Hunter L and b value between the fresh and odorless garlic, but value for greeness(-a) was lower in odorless garlic.
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이종원,김현영,최승은,정성은,이성철,박귀원,김우기,Lee, Jong-Won,Kim, Hyun-Young,Choi, Seung-Eun,Jung, Seung-Eun,Lee, Seong-Cheol,Park, Kwi-Won,Kim, Woo-Ki 대한소아외과학회 2002 소아외과 Vol.8 No.2
The aim of this study was to evaluate the posterior sagittal anorectoplasty (PSARP) as a re-do operation in patients who failed initial repair of anorectal malformation. Nine patients (4 boys and 5 girls) who had previous failed surgery for anorectal malformation underwent secondary operations through posterior sagittal approach. The main reasons of surgery were constipation (n=3) and persistent anatomical derangement in spite of previous correction surgery (n=6). In addition to constipation, the former group (n=3) had various anatomical defects, and the latter group (n=6), of course, had constipation in some degrees. Patients ranged in age from 2 to 19 years (median 3 years) with only one over the age of 6 years. The primary procedures included PSARP (n=8) and anoplasty (n=1). The rectum was mobilized from surrounding structures through posterior sagittal approach and anatomical defects were corrected. The rectum underwent reconstruction, which involved relocation of the rectum and anus within the limits of the intact muscle complex. Patients underwent follow-up for periods ranging from 6 to 77 months (mean 37 months) after surgery. Anatomical corrections of all the defects were successfully fulfilled in 9 patients. All the patients were satisfied with the functional results after redo-PSARP compared with the preoperative defecatory function. This study suggests that (1) some of the patients with troublesome constipation may have anatomical defects, prominent or hidden, (2) surgeons should suspect the possibility of anatomical defect as the cause of incontinence and (3) preoperative thorough investigation to reveal the anatomical defects should be included in estimating patients with severe incontinence after previous surgery and planning the correction for failed previous surgery as well.
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교모세포종 U-251MG, U-373MG세포주의 Cytokines처리에 의한 세포내 ICAM-1 발현
이종원,권정택,민병국,박승원,김영백,황성남,석종식,최덕영,Lee, Jong-Won,Kwon, Jung-Taek,Min, Byung-Kook,Park, Seung-Won,Kim, Young-Baeg,Hwang, Sung-Nam,Suk, Jong-Sik,Choi, Duck-Young 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.4
Objective : Despite advances in the understanding of tumor biology and the tumor immunology, there has been no effective treatment. The Intercellular adhesion molecule-1(ICAM-1) has been shown to be important in interaction involving cells of the immune system and to be upregulated in a number of cell culture systems by cytokines, including immune interferon($IFN-{\gamma}$) and tumor necrosis $factor-{\alpha}$($TNF-{\alpha}$). ICAM-1 has been identified as one of the ligands for lymphocyte function-associated antigen-1(LFA-1). The effectiveness of various cytokines to ICAM-1 induction on cultured human glioblastoma cell lines and potential efficacy of immunotherapy were studied. Method : Human glioblastoma cell lines, U-251 MG, U-373 MG were trypsinized and suspended at $1{\times}10^5cells/ml$ and grown on 8 well chamber slide, the cells were incubated in 0.3ml medium alone or medium containing $IFN-{\gamma}$(1000U/ml) or $TNF-{\alpha}$(250U/ml) or $IFN-{\gamma}$ plus $TNF-{\alpha}$ for 6, 12, 24, 48 and 72 hours. The coverslip were then removed and stained with a 1/30 dilution of anti-ICAM-1 antibody. Result : Surface antigen expression of ICAM-1 was increased by incubating glioblastoma cell lines with $IFN-{\gamma}$ and $TNF-{\alpha}$. Combined effect of $IFN-{\gamma}$ and $TNF-{\alpha}$ has induced more ICAM-1 expression on glioblastoma cell lines. Upregulation of ICAM-1 expression in an established glioblastoma cell line was of greater magnitude and more rapid following incubation with $IFN-{\gamma}$ plus $TNF-{\alpha}$. Surface antigen expression of ICAM-1 was increased for up to 48 hours after cytokine treatment on both cell lines(p<0.05). There was no difference on both cell lines(p>0.05). Conclusion : The results of the present study indicate that ICAM-1 expression in glioblastoma cell lines, U-251 MG and U-373 MG, are induced and enhanced after treatment with $IFN-{\gamma}$ and $TNF-{\alpha}$. Combined effect of $IFN-{\alpha}$ and $TNF-{\gamma}$ is stronger and more rapid than $IFN-{\gamma}$ or $TNF-{\alpha}$ alone.
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이종원(Lee, Jong-Won) 대한검도학회 2018 대한검도학회지 Vol.29 No.1
우리나라에서 검도본을 수련할 때 ‘선선의 선’이라는 생소하고도 어려운 개념에 봉착하게 된다. 일본에서는 “검도본 1, 2, 3, 5본은 후도가 ‘선선의 선’으로 선도를 이긴다”라고 규정하고 있지만, 우리나라에서는 모든 본은 ‘후의 선’이라고 하는 명확한 규정은 없지만 대부분의 검도 인들이 그렇게 인식하고 있다. 이 두 경우는 외형상으로는 별 차이가 없어 보이지만, 이론상으로는 분명히 다르다. 이 연구에서는 이러한 한일 간 검도본의 ‘선’에 관한 인식차이를 규명하고자 한다. 이를 위하여 한국과 일본에서 제기된 네 가지의 대표적인 주장(즉, 미야모토 무사시, 이종림, 타카노 사사부로, 전일본검도연맹)을 중심으로 분석하였다. 앞 두 주장은 현상 또는 동작 기준으로 제기된 것이고, 뒤 두 주장은 동작과 정신을 한 이중기준으로 하고 있다. 스포츠적 측면에서 보면 동작중심의 앞 두 주장이 타당하며, ‘선선의 선’ 개념이 없는 이 둘은 사실상 같은 것이다. 이 두 주장이 스포츠과학적으로 옳다고 하더라도, 문제는 ‘선선의 선’ 개념을 내포한 일본검도형을 설명할 수는 없다는 것이다. 따라서 일본검도형과 스포츠검도가 공존할 수 있는 유일한 방법은 ‘선선의 선’을 인정하는 것이다. 그러나 우리나라에서는 일본 각 유파의 전통을 계승한 검도본 즉 일본검도형의 정신을 받아들이기 어려운 실정이다. 따라서 필자는 향후 이에 대한 실증적인 연구가 수행되어 세계검도인이 객관적으로 또한 과학적으로 받아들일 수 있는 합리적인 연구를 기대하면서 과도기적인 기간에 우리나라에서는 일본의 ‘선선의 선’을 보다 광의의 개념인 한국의 ‘선의 선’ 개념에 포함시킬 것을 제안한다. 그리고 1, 2, 3, 4, 5본은 후의 선으로 종전과 같이 두더라도 후도의 기세에 눌려(또는 압박을 받아) 선도가 할 수 없이 치고 들어오는 6, 7본은 후도가 ‘선선의 선(또는 선의 선)’으로 승리하는 것이 아닐까 생각한다. 이에 대한 논의 또한 제안한다. When practicing Kendo Kata in Korea, we are confronted with the strangely difficult concept of "sensen no sen". In Japan, "Kendo Kata 1, 2, 3, and 5 say that the shidachi wins uchidachi (the person who initiates the move in order to teach the principles of the techniques) by "sensen-no-sen". In Korea, however, the most Kendoists recognize that all Kendo Kata are ‘go-nosen’ even though there are no clear regulations. These two cases do not seem to be largely different in appearances, but they are clearly different in theory. In this paper, the author tries to clarify the differences of perception on "Kendo Kata’s sen" between "Korea" and "Japan". For this purpose, four main arguments are advocated in Korea and Japan (i.e., Miyamoto Musashi, Rhee Jong-rim, Takano Saaburo, and All Japan Kendo Federation) were analyzed in this paper. The former two arguments are based on the criteria of appearance and/or movement; on the other hand, the latter two arguments are based on the two criteria, the movement and the spirit. In terms of sports perspectives, the two arguments, which are focused on the motion, are valid, and the two without the concept of "sensen no sen" are virtually the same. Even if these two arguments are right in sports science, the problem is that we can not explain Nippon Kendo Kata that contains the concept of "sensen no sen’. Therefore, the only way for Nippon Kendo Kata and sports Kendo to coexist is to admit the concept of ‘sensen no sen’. In Korea, however, it is very difficult to accept the spirit of Nippon Kendo Kata, which succeeded the traditions of each Kendo style in Japan. Therefore, the author expects that the world"s Kendo people will be able to objectively and scientifically accept the rational research that has been carried out through empirical researches in the future. However, during the transitional period the author proposes to incorporate the concept of "sensen no sen’ in Japan into the concept of ‘sen no sen’ in Korea which is a broader concept. Furthermore the author argues that Kendo Kata 1, 2, 3, 4, 5 would be classified into the concept of ‘go no sen’, but the shidachi (the person in the position of learning the techniques) of Kendo Kata 6, 7 might win by ‘sensen no sen’ because the uchidachi is compelled to attack under the pressure of the shidachi. The author also suggests a discussion on this.
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