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통상적인 투석처방을 받는 혈액투석 환자에서 실제 투석량에 영향을 미치는 인자의 분석
김연선 ( Yeun Sun Kim ),이현희 ( Hyun Hee Lee ),이종호 ( Jong Ho Lee ),김은수 ( Eun Soo Kim ),진경순 ( Kyoung Soon Jin ),김정곤 ( Jung Gon Kim ),유승민 ( Seung Min Yoo ),이준승 ( Joon Seung Lee ),정우경 ( Woo Kyung Chung ),주권욱 대한내과학회 2005 대한내과학회지 Vol.69 No.5
목적 : 적절한 혈액투석의 평가에 요소역동학을 이용한 Kt/V지표가 사용되나 일부 환자에서는 적절한 Kt/V값을 유지하지 못하여 이로 인한 임상적 문제가 발생할 수 있다. 저자들은 통상적인 주 3회, 회당 4시간의 혈액투석을 처방받는 환자에서 처방된 투석량과 전달된 투석량을 조사하고, 부적절한 투석량 전달에 미치는 요인을 분석하고자 하였다. 방법 : 안정된 상태로 투석 중인 97명의 만성신부전 환자를 대상으로 처방된 투석량은 Kt/V공식에서 K값으로 in vitro 요소청소율을 V값으로 Watson 식을 이용한 요소분포용적을 구하여 계산하였고, 전달된 투석량은 Daugirdas의 single pool, variable volume공식을 사용하여 계산하였다. 또, 전달된 투석량에 영향을 줄 수 있는 기술적, 임상적 인자들별로 전달된 투석량의 차이를 분석하였다. 결과 : 처방된 투석량의 평균은 1.37±0.21, 전달된 투석량의 평균은 1.23±0.27로 양의 상관관계는 있었으나 유의한 차이를 보였다(p<0.03). 전달된 투석량이 1.2 미만인 군은 45%였고, 이 군은 체중이 높았으며, 투석 처방량이 낮았다. ΔKt/V값은 헤파린을 사용한 군에서 사용하지 않은 군에 비해 유의하게 낮았으며(0.11±0.16 vs. 0.28±0.20, p<0.002), 저혈압, 투석 중 증상, 투석시간의 단축, 재순환율 등의 인자에 따른 차이는 보이지 않았다. 결론 : 통상적인 투석 처방으로 혈액투석 중인 환자에서 체중, 투석 처방량, 헤파린 사용 여부 등의 인자들이 투석의 적절도에 영향을 줄 수 있으므로 환자에 따른 개별적 처방이 필요함을 알 수 있었다. Background : Although adequate removal of small solutes are essential for effective hemodialysis, many patients are suffering from inadequate delivery of hemodialysis, especially with the conventional fixed regimen of dialysis for 4 hours three times per week. We tried to evaluate actual delivered dose of hemodialysis in patients receiving 4 hours of low-flux hemodialysis, and to analyze factors affecting inadequate delivery of hemodialysis. Methods : 97 stable maintenance hemodialysis patients who were undergoing 4 hours of hemodialysis thrice weekly were included for analysis. Prescribed dose of dialysis was calculated by Kt/V where K was in vitro urea clearance of dialyzer membrane and V was estimated according to the Watson`s formula. Delivered dose of dialysis was calculated according to the Daugirdas equation. To find factors that may impair adequate delivery of hemodialysis, various clinical and technical parameters were analyzed. Results : Prescribed dose of hemodialysis was 1.37±0.21, while delivered dose was 1.23±0.27, and thus, there was a significant difference (p<0.03). In 45% of the patients, delivered dose was less than 1.2. They were heavier and prescribed dose was low. ΔKt/V (Prescribed dose-Delivered dose) was significantly greater in patients who did not use heparin therapy compared to patients who used heparin. Other parameters such as hypotension, missed treatment, sex, type of vascular access and degree of recirculation were not associated with impaired delivery of hemodialysis. Conclusions : Delivered dose of hemodialysis can be affected by patient`s body weight, prescribed dose and heparin use in conventional low-flux hemodilaysis regimen. Therefore, each patient should be prescribed individually for adequate delivery of hemodialysis, and delivered dose should be measured regularly.(Korean J Med 69:510-517, 2005)
박태선(Tae-Seon Park),박홍규(Hong-Kyu Park),홍승우(Seong-Woo Hong),김정곤(Jeong-Gon Kim),정남진(Nam-Jin Chung),조현숙(Hyun-Suk Cho),성기영(Ki-Yeong Seong),양운호(Woon-Ho Yang),서명철(Myung-Chul Seo),강항원(Hang-Won Kang) 韓國雜草學會 2012 Weed&Turfgrass Science Vol.32 No.3
본 시험은 몇몇 사료용 피들의 생육특성과 논에서 잡초화 방지를 위하여 국내 논에서 사용량이 많은 제초제들에 대한 반응을 조사하기 위하여 실시되었다. 겨울철 유리 온실 내의 대형 콘크리트 폿트에서 사료 가능성이 높은 피 8계통들의 생육을 조사한 결과 IT170609, IT196421 그리고 EV2012 계통들이 건물중 생산성이 상대적으로 높았다. 출수기에 따른 품종적 특성은 IT170609 계통은 중만생종, IT196421 및 EV2012 계통들은 만생종으로 나타났다. 선발된 사료용 피 3계통에 대한 발아율은 재래종인 강피 보다 높았고, 20 및 25℃에서 뚜렷하였다. 논에서 사료용 피들의 잡초화 방지를 위한 제초제 시험에서 토양처리제인 imazosulfuron+benzobicyclone+penoxsulam 액상수화제는 사료용 피 3계통에 대하여 90% 이상의 효과를 보였다. 경엽처리 제초제들인 cyhalofop-butyl 유제, penoxsulam 액상수화제, metamifop 유제는 사료용 피 6~7엽기까지 매우 높은 효과를 보였다. This experiment was conducted to determine the agronomic characteristics for selection of the excellent barnyard millet and the herbicidal response for their weediness prevention in paddy rice. IT170609, IT195422 and EV2012 have produced more dry matter compared to other barnyard millets tested. In varietal characteristics by heading date, IT170609 showed medium maturing type and IT195422 and EV201 had late maturing type. The germination rate of IT170609, IT195422 and EV2012 on temperature was higher than Echnochloa oryzicola of native species, and it was definitely distinctive at 20 and 25℃. In the herbicidal response for their weediness prevention in paddy rice, imazosulfuron+benzobicyclone+penoxsulam SC showed control effect the extend of over 90% to IT170609, IT195422 and EV2012. Cyhalofop-butyl EC, penoxsulam SC and metamifop EC were very effective by 6~7 leaf stage of barnyard millets tested.
생약제제 중 이산화황 잔류실태 시중 유통 생약제제 중 이산화황의 잔류실태 조사
이춘영(Chun-Yeong Lee),이정숙(Jeong-Sook Lee),이현경(Hyun-Kyung Lee),박원희(Won-Hee Park),김정곤(Jeong-Gon Kim),정애희(Ae-Hee Chung) 대한약학회 2012 약학회지 Vol.56 No.1
This study was carried out to investigate the content of sulfur dioxide residues in the medicine prepared from crue drugs. Total 29 pills that contains salvia miltiorrhiza root, anemarrhena rhizome, fritillaria bulb, glehnia root, asparagus tuber, lycium fruit, moutan root bark, cimicifuga rhizome, pinellia tuber, dipsaci radix, codonopsis pilosula root, liriope tuber, achyranthes root, prepared aconite, aurantii fructus immaturus, corydalis tuber, dioscorea rhizome were examined by the modified Monier_Willams method. Sulfur dioxide were detectd in all the tested samples, and were found over MRLs (30 mg/kg to medicinal herbs) in 8 samples (27.6%). Especilly, "i2" pills contains 132.46 mg/kg sulfur dioxide that is 4 times over than MRLs.
全泰玉,朴興植,鄭明眞,金晶坤 동아대학교 공과대학 부설 한국자원개발연구소 1988 硏究報告 Vol.12 No.2
This paper has been carried out ot clarify the behavior of the BUE experimented Aluminium with using tungsten caribide tools. The results obtained are as follow : There was the block that varied suddenly at the initial cutting force. From the point of cutting distance 150㎜ Happened the BUE and the cutting force was the normal state. As share angle is increased, compression coefficient of the chip are increased. Relation between the friction coefficient of chip side and tool rake side can make the modelization studying the BUE size. As cutting speed is increased, chip thickness is decreased.