Minimally Invasive Laser-Assisted Biopsy of the Oral Lesions for Oral Graft-Versus-Host Disease after Hematopoietic Stem-Cell Transplantation

김윤미,윤희정,김현실,김기덕,정복영,방난심,박원서,Kim, Yun-Mi,Yun, Hee-Jung,Kim, Hyun-Sil,Kim, Kee-Deog,Jung, Bock-Young,Pang, Nan-Sim,Park, Won-Se The Korean Academy of Orofacial Pain and Oral Medi 2012 Journal of Oral Medicine and Pain Vol.37 No.3

조혈줄기세포이식은 면역 결핍 질환, 자가 면역 질환, 악성 조혈 종양의 주된 치료법이다. 이종 조혈줄기세포이식의 주요한 합병증은 이식편대 숙주질환이다. 구강 점막 생검은 이식편대 숙주 질환의 확진과 치료계획 수립을 위해 필요하나 영양 결핍과 화학 요법으로 인해 전신상태가 불량한 환자에게 출혈과 균혈증을 일으킨다. 본 논문에서는 레이저를 이용한 최소 침습적 조직생검의 효능을 평가하였다. 모두 3개의 증례가 소개되었고 모든 환자의 의료 기록, 임상 사진, 조직병리학적 결과가 레이저를 이용한 조직생검의 효능을 평가하기 위해 검토되었다. 모든 환자는 생검 후 불편감이 없었고 심각한 합병증이 발생하지 않았다. 생검 조직의 질이 이식편대 숙주 질환을 확진하는 데에 적당했다. 구강 점막의 레이저를 이용한 최소 침습적 생검은 통상의 조직병리학적 생검에 비해 출혈을 일으키지 않아 감염과 균혈증, 술 후 흉터 생성을 줄이므로 이식편대 숙주 질환의 확진에 이로울 것이다. Hematopoietic stem-cell transplantation (HSCT) is a treatment for immune deficiency, autoimmune diseases, and hematopoietic malignancies. The main complication of allogenic HSCT is graft-versus-host disease (GVHD). Oral mucosal biopsy is needed for a definitive diagnosis and treatment planning of GVHD, but this procedure causes bleeding and bacteremia in a poor general condition. We evaluated the efficacy of laser-assisted biopsy as a minimally invasive treatment. Three cases were described in this article. All patients' medical records, clinical photographs, and histopathologic findings were reviewed. All patients felt comfortable and no severe complications occurred. The quality of the obtained biopsy material was adequate for a definitive diagnosis of GVHD. Laser-assisted, minimally invasive biopsy of the oral mucosa does not cause bleeding, and it reduces the chances of infection, bacteremia, and postoperative scarring compared to the usual histopathologic biopsy procedure. It would thus be advantageous to use this procedure to biopsy GVHD patients.

치료용 테이핑이 정상 성인의 배곧은근 근력에 미치는 영향

김윤미,박희정,송지욱,이문환,이현민,김용권,Kim, Yun-Mi,Park, Hee-Jung,Song, Ji-Uk,Lee, Moon-Hwan,Lee, Hyun-Min,Kim, Young-Kwon 대한물리치료과학회 2010 대한물리치료과학회지 Vol.17 No.1

Background: In recent days, Taping has introduced developing to improve our muscle power and sustaining power more than a fixed idea that taping only functions for muscles and protection of the articulation. Method: This study were conducting in two weeks - 2009 September 1 to September 14 - investigating at random 24 normal adults in H university located at Jinju Korea and the result of experimentation how the application of kinesio taping and Bang-gue taping(B-GT) to rectus abdominal muscle has an effect on the improvement of abdominal muscle strength. Results: the following conclusion was drawn up: 1. As a result of each experience man and woman with abdominal muscle strength, each experience all man and woman with abdominal muscle strength(p=0.01) came out to have interrelation difference. 2. As a result of comparing B-GT with age-abdominal muscle strength, B-GT(p=0.02) came out to have interrelation difference. 3. As a result of comparing after before kinesio taping and after before B-GT with abdominal muscle strength, after before kinesio taping and after before B-GT(p=0.00) came out to have interrelation difference. Also, as a result of comparing after kinesio B-GT, after kinesio B-GT(p=0.03) came out to have interrelation difference. Conclusion: As mentioned above, this study showed how the application of kinesio taping and B-GT to affected the improvement of abdominal muscle strength.

임부의 성생활에 관한 조사연구

김윤미,박영숙,Kim, Yun-Mi,Park, Young-Sook 한국여성건강간호학회 1997 여성건강간호학회지 Vol.3 No.1

A Pregnancy is the women's normal physiological and developmental process, in which many psychological changes including sexual problems always occur. But there have been few guidelines on sexual life during pregnancy. So this study was performed to evaluate the sexual life of pregnant women, and to analyze the factors affecting satisfaction of sexual life during pregnancy. Questionnaires were given to pregnant women who visited two general hospitals for antenatal care as well as to attendants at a prenatal Lamaze class. The results were as followings : 1) The average age of the 194 pregnant women was 28.5 years ; 98.4% of them had educated more than 12 years. ; the average monthly income was about 15,000,000 won ; primigravida women were 81.4% of the total cases. 2) As the pregnancy progressed, the frequency of the sexual intercourses was decreased in 48.5% because of the anxiety on the fetal damages. The was no significant differences between frequency of sexual intercourses and the degrees of physical discomfort and spouse intimacy. Man superior position was taken in 88.1% ; the incidence of orgasms before and during pregnancy were 71.1% and 41.1%, respectively ; the incidence of painful sexual intercourse in primigravida women was decreased by pregnancy in 4.6%, and in the case of multigravida women it was increased in 2.1%. 3) The average point of sexual knowledge was 11.5 in total points of 20 ; that of sexual attitude was 29.1 in total points of 40 ; that of sexual satisfaction was 28.5 in perfects points of 40. 4) The factors which significantly related to the satisfaction of sexual life were spouse intimacy, sexual attitude, change of sexual body position during pregnancy, and the orgasms before and during pregnancy. Considering above results, nursing care and nursing intervention including sexual education and counselling programs are needed during pregnancy as well as before pregnancy.

Synthesis and Characterization of Poly[9,10-diphenylanthracene-4$^\prime$, 4$^\prime^\prime$-ylenevinylene-3,6-(N-2-ethylhexyl)carbazole]

김윤미,박기민,권순기,Kim, Yun Mi,Park, Gi Min,Gwon, Sun Gi Korean Chemical Society 2001 Bulletin of the Korean Chemical Society Vol.22 No.9

A novel poly[9,10-diphenylanthracene-4',4"-ylenevinylene-3,6-(N-2-ethyl hexyl)carbazole] containing alternate diphenylanthracene and carbazole unit was synthesized by the Wittig reaction. The obtained polymer was soluble in common organic solvents and thermally stable up to 380 $^{\circ}C.$ The polymer gives rise to bright blue fluorescence both in solution and in thin solid films. The light emitted from the device (ITO/polymer/Al) was greenish-blue in color and clearly visible in daylight.

자연친화적 교육활동 프로그램이 유아의 행복감 및 자아개념에 미치는 영향

김윤미(Kim Yun-Mi),정영희(Jung Young-Hee) 한국열린유아교육학회 2011 열린유아교육연구 Vol.16 No.2

본 연구는 자연친화적 교육활동 프로그램을 적용하였을 때 유아의 행복감과 자아개념이 어떠한 변화하는 지를 알아보기 위한 목적으로 이루어졌다. 만 4세 유아 50명을 대상으로 연구를 실시하였다. 실험집단 유아에게는 9주 간 16회의 자연친화적 교육활동을 적용하였고, 비교집단 유아에게는 일상적인 교육과정 운영계획에 따른 교육활동을 실시하였다. 연구에 사용된 측정도구는 유아용 행복척도와 자아개념 검사도구이다. 연구결과 자연친화적 교육활동 프로그램을 적용한 실험집단 유아에게는 행복감과 자아개념 증진에 긍정적 효과가 있었다. 또한 유아의 행복감과 자아개념 점수 간에는 유의미한 정적 상관관계가 있는 것으로 나타났다. This study intended to promote children's happiness and improve their self-concept when they enjoy and explore nature through nature friendly education activities. They would feel psychologically stable, explore and approach the environment around them more actively, enhance confidence in everything, form a positive self-concept of themselves and others, and feel happy. The research questions were as follows: 1. Are nature friendly education activities effective in increasing children's happiness? 2. Are nature friendly education activities effective in enhancing children's self-concept? Twenty-five children, all of whom were 4 years old, at a kindergarten in C province composed the experimental group, and another 25 children at the same age at a different kindergarten in the same region constituted the control group, which resulted in 50 subjects. The children in the experimental group participated in 16 nature friendly education activities in total, twice a week, for 9 weeks. The results of the study were as follows: 1. The Nature friendly education activities were effective at increasing children's happiness. 2. The Nature friendly education activities were positively effective in enhancing children's self-concept. These results prove that the nature friendly education activities increase children's happiness and they positively affect self-concept development. Also, the nature friendly education activities can be a good means for children to begin living a happy life by constantly improving abilities related to selfconcept, such as skills to satisfy their needs, feeling of joy, social relationship and so on, when this interrelatedness between happiness and self-concept is fully considered.

현대문학 : 발터 벤야민과 로버트 발저의 자전적 글쓰기

김윤미 ( Yun Mi Kim ) 한국브레히트학회 2013 브레히트와 현대연극 Vol.0 No.29

Walter Benjamin (1892-1940) und Robert Walser (1878-1956) waren sich im Leben weder begegnet noch haben sie in irgendeiner Form miteinander kommuniziert. Walser kannte Benjamin kaum. Benjamin las hingegen einige von Walsers Dramoletten und Prosawerken und verfasste zumindest einen kurzen aber fur die Walserforschung bedeutenden Essay uber sie. Wenngleich weder Freundschaft noch Bekanntschaft beide Autoren verband, weisen ihre Arbeiten interessanterweise vielfache Parallelen auf. In besonderem Maße lasst sich dies an ihren autobiographischen Schriften belegen. Auch wenn Benjamin seine Berliner Kindheit um 1900 nicht der Autobiographie zugeordnet wissen und Walser hingegen praktisch ‘alles’ aus eigener Feder als Teile der Autobiographie ansehen wollte, haben sie eines gemeinsam: ihre ‘autobiographischen’ Schriften unterminieren das herkommliche Gattungsverstandnis von der Autobiographie. So sind die Charakteristiken ihres autobiographischen Schreibens: Eine große Lust des Ichs am Verstecktbleiben und Nichterkanntwerden; Die unwillkurliche Erinnerung als Feder fuhrender Faktor; Nicht stark prasentes ordnendes Subjekt; Metapher des Labyrinths; Schließlich verwenden die beiden Worter wie zerschlagen, zerschnitten und zertrennt, um ihre autobiographischen Schriften mit ihren nicht nach Vollendung strebenden und ewig fragmentarisch-provisorischen Zugen zu charakterisieren. Diesen Grundzugen ihres autobiographischen Schreibens geht dieser Beitrag nach. Dabei werden besonders Texte aus Berliner Chronik, Berliner Kindheit um 1900 von Benjamin und Mikrogrammen von Walser herangezogen.

VMD기법을 적용한 전통술 기업복합문화공간 실내공간 계획 연구

김윤미(Kim, Yun-Mi),김이홍(Kim, lee-hong) 한국실내디자인학회 2022 한국실내디자인학회 학술대회논문집 Vol.24 No.1

산후 우울의 고찰: 정신신경면역계 상호작용을 중심으로

김윤미 ( Yun Mi Kim ),안숙희 ( Suk Hee Ahn ) 여성건강간호학회 2015 여성건강간호학회지 Vol.21 No.2

Purpose: The purpose of this review was to describe a psychoneuroimmunology (PNI) framework for postpartum depression (PPD) and discuss its implications for nursing research and practice for postpartum women. Methods: This study explored the role of hypothalamic-pituitary-adrenal (HPA) axis and inflammation as possible mediators of risk factors for PPD through literature review. Results: From this PNI view, human bodies are designed to respond with the reciprocal interactions among the neuro-endocrine and immune system when they are faced with physical or psychological stressors. Chronic stress induces alterations in the function of HPA axis, and a chronic low-grade inflammatory response is associated with depression. The dysfunctions of cytokines and HPA axis have been observed during the postpartum period. Stress promotes glucocorticoid receptor resistance, which can promote inflammatory responses. This, in turn, can contribute to the pathophysiology of depression. This can especially affect populations at vulnerable time-points, such as women in the postpartum. Conclusion: From a PNI perspective, well-designed prospective research evaluating the role of stress and inflammation as an etiology of PPD and the effect of stress reduction is warranted to prevent PPD.

‘조선군 임시병참사령부’의 부산 숙영 시행과 지역 변화

김윤미(Kim, Yun-Mi) 부산경남사학회 2018 역사와 경계 Vol.109 No.-

부산은 일본 군사수송의 중계지였다. 1937년 7월 중일전쟁을 일으킨 일본은 2개월간 3차례에 걸쳐 병력 20.9만명, 말 4.5만필, 후방부대, 물자 등을 긴급수송 했다. 부산에서 수송을 총괄한 것은 조선군 임시병참사령부 부산지부였다. 부산병참지부는 부산 내 각 단체들과 숙영 전반의 지원을 협의했고, 부산부의 전 일본인 가옥을 대상으로 군인들을 숙영시켰다. 급히 마계장도 설치하여 군마 숙영도 시행했다. 이 글은 군의 숙영지가 없는 지역에 어떻게 군인과 군마가 숙영하고, 군사수송은 지역에 어떠한 영향을 끼쳤는지 살펴보고자 했다. 부산병참지부의 보고서를 토대로 군사수송과 지역의 관계에 대해 몇 가지 사안을 주목했다. 첫째는 대규모의 부대가 부산에 숙영하면서 이들을 통제할 장치가 갖추어지지 않았고, 이것은 지역의 사회적 문제로 내재되어 있었다. 둘째는 소비가 확대되면서 물가가 급등했고, 부산병참지부는 부산부청과 함께 물가를 통제하기 위해 여러 가지 조치를 취했다. 셋째는 부산병참지부의 대규모 예산이 부산부민과 부산 지역에 직접 지출되면서 지역 경제의 순환으로 이어졌다. 넷째는 군사수송을 우선하여 보통열차의 운행 횟수 감소, 철도 화물취급 제한, 선박의 부두 사용 통제 등의 일련의 제제는 상업 도시인 부산의 경제에 악영향을 끼쳤다. 다섯째는 부산병참지부에서 향후 숙영지 확보가 반드시 필요하다고 보았고, 이것은 1937년 부산시가지계획 시행과 1940년대 부산에 들어선 군사시설과 무관하지 않다. 여섯째는 민가숙영지 설정시 제외된 조선인들에게는 지역의 경제 활성화의 영향이 제한적이었을 것으로 추정된다. The modern history of Korea was a period of war. The war did not take place directly on the Korean Peninsula, but it played a role in the rear for the Japanese war. How did this affect the Korean Peninsula? The answers under the subjects of Japanese army and logistics, military and region, war and transportation will be discovered. This thesis determined the area of Busan in the perspective of war and army. Japan opened Gyeongbu Line and Gyeongui Line in 1905, and used the railroad of Joseon as a means of military transportation. Despite the difference in scale and means, the military transportation continued until 1945. Busan also served as military camps. Camp is a place where the troop takes a rest or gathers in the rear to prepare for future movement. Japan started the dispatch of Siberian troops in 1918, Manchurian Incident in 1931, Sino-Japanese War in 1937, and Asia-Pacific War in 1941, and implemented a massive emergency transportation. All the soldiers of considerable size passed through Busan. As it was unable to find any data from the 1940s, the military transportation immediately after the Sino-Japanese war in 1937 was considered the research period and subject. This is because transportation reports are still remaining that recorded the Japanese army"s military quarters, food service, hygiene, military horse, and support of local people in September 1937. As a result, many influences to the region by the army were identified, including the social economy of Busan, lifestyles of residents and urban planning.

20세기 초 독일 소설의 바그너 수용 - 토마스 만의 『벨중의 혈통』, 아르투어 슈니츨러의 『야외로 가는 길』, 프란츠 베르펠의 『베르디』를 중심으로

김윤미 ( Kim Yun-mi ) 한국독일언어문학회 2016 독일언어문학 Vol.0 No.74

Um 1900 beobachtet sich ein Phanomen um Richard Wagner, das einem Kult vergleichbar ist. Die Wirkung von Richard Wagner und seinem Werk blieb dabei nicht nur auf die Musikwelt beschrankt. Auch in der Literatur wird sie stark reflektiert. Zahlreiche und namhafte Autoren haben sich mit dem Thema `Wagner und seine Musik` beschaftigt. Im vorliegenden Beitrag wird anhand einiger Erzahltexte das europaweite Wagner-Phanomen um 1900 ins Auge gefasst. Vorab zu erwahnen ist, dass es bei der Wagnerrezeption nicht immer eine klare Trennlinie zwischen der Person Wagner und der seiner Werke zu ziehen ist. Zur naheren Betrachtung werden Thomas Manns Walsungenblut, Arthur Schnitzlers Der Weg ins Freie und Franz Werfels Verdi herangezogen. Ziel ist es dabei, einen Protagonistentypus, den jungen dekadenten Wagnerschwarmer, zu charakterisieren und diesen im Zusammenhang der Wagnerschen Musik zu sehen. Techniken wie Halbtone, Dissonanzen und unendliche Melodien, die vor allem Wagners Spatwerke pragen, werden im Erzahlgefuge effektiv eingesetzt. Sie helfen dabei, die Denk- und Handlungsweise der Protagonisten zu ergrunden. Bei Musik mit diesen Techniken werden Eindrucke und Gefuhle wie dauernde Verschiebung und endloses Warten auf den entscheidenden Moment hervorgerufen. Außerdem ´opfern sich´ die Frauengestalten wie in Wagneropern, um die mannlichen Protagonisten als narzisstische und dilettantische Kunstlerfigur zu ´befreien´. Auch das literarische Erscheinungsbild von der Person Wagner selbst bleibt nicht unbeleuchtet. Wagner wirkt uber die Gaben als großer Komponist hinaus oft als ein monologisierender Selbstdarsteller, als `Schauspieler`. Er wird zudem in seiner Wirkung als ein geheimnisvoll verfuhrerischer, erotisierender Mensch gezeichnet.