회원작품 - 이도재(履道齋)

김상진,Kim, Sang-Jin 대한건축사협회 2009 建築士 Vol.2009 No.11

면역약침을 병행한 만성 전립선염/만성 골반통 증후군 환자 치험 1례

김상진,김보겸,강순성,정희재,정승기,이범준,Kim, Sang-jin,Kim, Bo-kyum,Kang, Soon-sung,Jung, Hee-jae,Jung, Sumg-ki,Lee, Beom-joon 대한한방내과학회 2015 大韓韓方內科學會誌 Vol.36 No.3

Objectives The purpose of this study is to report the clinical effects of immuno pharmacopuncture and herbal medicine Simmidojeok-san on chronic non-bacterial prostatitis. Methods The patient was treated with Simmidojeok-san ; 0.2 cc of V pharmacopuncture injection was given into Jeonyang and 0.6 cc of V pharmacopuncture injection was administered into Hoeeum (CV1). National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) and Numerous Rating Scale (NRS) were used to assess treatment effect. Results NIH-CPSI and NRS decreased after treatment. Conclusions The herbal medicine Simmidojeok-san and V pharmacopuncture therapy are effective in treating chronic non-bacterial prostatitis.

Olefin Separation Membranes Based on PEO/PDMS-g-POEM Blends Containing AgBF₄/Al(NO₃)₃ Mixed Salts

김상진,정정표,박철훈,김종학,Kim, Sang Jin,Jung, Jung Pyu,Park, Cheol Hun,Kim, Jong Hak The Membrane Society of Korea 2015 멤브레인 Vol.25 No.6

촉진수송은 기존의 고분자 막에서는 힘든, 투과도와 선택도를 동시에 향상시킬 수 있는 기술 중 한 가지이다. 촉진수송 분리막을 이용한 올레핀/파라핀 분리는 기존의 증류공정을 대체할 수 있는 기술로써 많은 관심을 받아왔다. 본 연구에서는 테트라플루오로붕산은/질산알루미늄의 혼합염이 포함된 고분자 블렌드 기반의 촉진수송 올레핀 분리막을 제조하였다. 자유 라디칼중합법을 이용하여 폴리다이메틸실록세인-g-폴리옥시에틸렌 메타크릴레이트 가지형 공중합체를 합성하였다. 또한, 폴리다이메틸실록세인-g-폴리옥시에틸렌 메타크릴레이트 매질에 폴리에틸렌옥사이드를 다양한 비율로 혼합하였다. 폴리에틸렌옥사이드를 폴리다이메틸실록세인-g-폴리옥시에틸렌 메타크릴레이트 가지형 공중합체 질량 대비 70%를 혼합하였을 때, 혼합기체 선택도 및 투과도는 5.6 및 10.05 GPU에 도달하였다. 이와 같은 복합막의 올레핀 분리 성능이 향상된 이유는, 분리막에 첨가된 은이온이 올레핀 기체분자의 선택적인 촉진 수송을 하였고, 또한 고투과성의 고분자 블렌드가 사용되었기 때문이다. 또한 은이온의 은나노입자로의 환원을 억제시키는 질산알루미늄의 첨가로 인해 복합막의 장시간 안정도를 향상시킬 수 있었다. Facilitated transport is one of the possible solutions to simultaneously improve permeability and selectivity, which is challenging in conventional polymer-based membranes. Olefin/paraffin separation using facilitated transport membrane has received much attention as an alternative solution to the conventional distillation process. Herein, we report olefin separation composite membranes based on the polymer blends containing $AgBF_4/Al(NO_3)_3$ mixed salts. Free radical polymerization process was used to synthesize an amphiphilic graft copolymer of poly(dimethyl siloxane)-graft- poly(ethylene glycol) methyl ether methacrylate (PDMS-g-POEM). In addition, poly(ethylene oxide) (PEO) was introduced to the PDMS-g-POEM graft copolymer to form polymer blends with various ratios. The propylene/propane mixed-gas selectivity and permeance reached up to 5.6 and 10.05 GPU, respectively, when the PEO loading was 70 wt% in polymer blend. The improvement of olefin separation performance was attributed to the olefin facilitating silver ions as well as the highly permeable blend matrix. The stabilization of silver ions in the composite membrane was achieved through the introduction of $Al(NO_3)_3$ which suppressed the reduction of silver ions to silver particles.

유류에 오염된 아비류 (Loons)의 체내 조직 중 필수원소 농도

김상진,이종남,이두표,Kim Sang-Jin,Lee Jong-Nam,Lee Doo-Pyo 환경독성보건학회 2006 환경독성보건학회지 Vol.21 No.3

Concentrations of four essential metals (Fe, Cu, Mn and Zn) were determined in apparently oil-polluted dead or near-dead three loon species collected in the Busan coast, Korea. Fe, Cu, Mn and Zn concentrations were generally high in liver, and also, Mn and Zn were high in bone. There were significant differences in some tissue concentrations of Fe, Cu, Mn and Zn among three species, but did not show any consistent evidence of species-specific accumulation. Mean concentration of Fe was 11,635$\pm$4010 $\mu$g/g, Cu 64.3$\pm$30.7 $\mu$g/g, Mn 13.1$\pm$2.32 $\mu$g/g, and Zn 121$\pm$24.8 $\mu$g/g in liver of all three species examined. Mn and Zn levels in this study were similar to those of normal loons and other seabirds reported from different countries. However, Fe and Cu liver levels were extraordinarily higher than those of reported. This result suggests that unusual accumulations of essential metals such as Fe and Cu may partially arise from long-term starvation due to oil pollution.

Exponential Nozzle을 사용한 Water Jet 발생에 관한 연구

김상진,윤의수,최태민,Kim, Sang-Jin,Yun, Ui-Su,Choe, Tae-Min 한국기계연구원 1990 기계연구원소보 Vol.20 No.-

Most water cannon machines use compressed gas to accelerate a piston which extrudes water through a cumulation nozzle. Very high jet stagnation-pressures can be achieved by using a specially-shaped nozzle which is initially filled with air or vacuum. The objective of this study was to establish the basic technology of water cannon using exponential type nozzle. An experimental water cannon including high pressure components such as exponential nozzle and 300atm air resrvior were designed and tested. Parameters that influence the performance of the system and jet characteristics were examined.

흉부 방사선 영상의 정점영역 매칭을 통한 허파영역 자동검출에 관한 연구

김상진,김용만,이명호,Kim, Sang-jin,Kim, Yong-Man,Lee, Myoung-Ho 대한의용생체공학회 1990 의공학회지 Vol.11 No.2

This paper presents a new algorithm that extracted lung region in X-ray and enhanced the region. With a lung region that was extracted by histogram threshold value, it was diffi cult to detect perfect lung boundary. Therefore we presented perfect lung boundary detection method using apex detection and apex region restoration. Also, by applying modified equalization algorithm and presented function to inside of lung region, we want to give help to automatic diagnosis In X-ray chest image. Presented main line trace algorithm gave good result in detection of lung boundary And, as apex detection method using lung row and column gray level average value found more correct place of lung than the rpethod of prior algorithm, we succeeded perfect lung region detection, Also, presented function that had lung region's gray level distribution characteristic was very effective to image enhancement.

미국.일본의 심해생명공학 연구동향

김상진,Kim, Sang-Jin 한국미생물학회 2003 微生物과 産業 Vol.29 No.2

Room Temperature Phosphorescence from Inclusion Complex of ${\beta}$-Cyclodextrin and 1-Bromonaphthalene in the Presence of Phenol and 1-Butanol

김상진,Kim, Sang Jin 대한화학회 2001 Bulletin of the Korean Chemical Society Vol.22 No.12

3${\beta}$-Hydroxy-12-oleanen-28-oic Acid 유도체들의 PTP-1B저해활성에 대한 CoMSIA분석

김상진,정영호,김세곤,성낙도,Kim, Sang-Jin,Chung, Young-Ho,Kim, Se-Gon,Sung, Nack-Do 한국응용생명화학회 2008 Applied Biological Chemistry (Appl Biol Chem) Vol.51 No.3

기질 화합물로써 3${\beta}$-Hydroxy-12-oleanen-28-oic acid 유도체(1-30)들과 그들의 protein tyrosine phosphatase(PTP)-1B 저해활성에 관한 비교분자 유사성 지수분석(CoMSIA)보델을 유도하였다. QSAR 모델의 통계 값은 CoMFA>CoMSIA${\geq}$HQSAR>2D-QSAR 모델의 순서로 양호하였다. 최적화된 CoMSIA F1 모델은 grid 3.0${\AA}$과 field fit 정렬조건에서 가장 족은 예측성과 상관성($r^2_{cf}$=0.754 및 $r^2_{ncv}$=0.976)을 나타내었다. 저해 활성에 관한 CoMSIA상의 기여비율(%)은 수소결합 받게장(48.9%), 입체장(25.8%) 및 소수성장(25.4%)의 순서이었다. 그러므로 기질 화합물의 PTP-1B에 대한 저해활성은 $R_4$-치환기의 수소결합 받게 장(A)에 의존적이었다. 등고도 분석 결과로부터 $R_1$-치환기는 수소결합 받게장이 작고 $R_3$-치환기는 입체장이 작으며 그리고 $R_4$-치환기는 수소결합 받게장, 소수성 및 입체장이 큰 치환기가 저해활성을 증가시킬 것으로 예측되었다. The comparative molecular similarity indices analysis (CoMSIA) models between 3${\beta}$-Hydroxy-12-oleanen-28-oic acid (1-30) analogues as substrate molecule and their inhibitory activities ($pI_{50}$) against protein tyrosine phosphatase (PTP)-1B were derived and discussed quantitatively. Listing in order, the CoMFA>CoMSIA${\geq}$HQSAR>2D-QSAR model, these QSAR models had the better statistical values. The optimized CoMSIA F1 model at grid 3.0${\AA}$ had the best predictability and fitness ($q^2$=0.754 and $r^2$=0.976) by field fit alignment. The order of contribution ratio (%) of CoMSIA fields concerning the inhibitory activities was a H-bond acceptor (48.9%), steric field (25.8%) and hydrophobic field (25.4%), respectively. Therefore, the inhibitory activities of substrate molecules against PTP-1B were dependent upon H-bond acceptor field (A) of $R_4$-group. From the analytical results of CoMSIA contour maps, oleanolic acid derivatives will have better inhibition activities if $R_1$ group has H-bond acceptor disfavor, $R_3$group has steric disfavor and $R_4$ group has steric, hydrophobic, H-bond favor.

대테러활동에 있어서 민간군사보안업(PMSCs) 제도의 도입과 활용방안

김상진,김종걸,Kim, Sang-Jin,Kim, Jong-Kul 한국융합보안학회 2011 융합보안 논문지 Vol.11 No.5

한국의 대테러 활동은 군과 경찰력만으로 모든 환경을 통제하기에는 현실적으로 불가능하다. 그러나 군과 경찰은 자신들의 영역만을 고수한 채 여전히 보수적이고 폐쇄적인 운영을 강조하고 있다. 또한, 한국의 대테러 활동은 사전예방 활동이라기 보다는 사후대응활동에 중심을 두고 있어서 사실상 무방비 상태이다. 이러한 문제점을 해결하기 위해서는 대 테러 전문가로 구성된 민간차원의 협력체를 구성해야 한다. 그 대안으로 이 연구에서는 PMSCs(Private Military Companies: 민간군사보안업체)제도를 도입하여 활용하는 방안을 모색하였다. 그 결과, 첫째, 법적 근거에 대한 당위성을 마련하는 것이 우선적으로 요구되어지는데, 이를 위해서는 무엇보다도 공 사간의 파트너십을 위한 의식전환이 요구된다. 둘째, 전문성을 갖춘 PMSCs를 활용하기 위해서는 군이나 경찰기관에서 대테러 실무 경험이 있는 전문가 집단을 중심으로 퇴역 후 PMSCs에 재취업을 할 수 있도록 사전에 공 사간 인프라가 구축되어야 한다. 셋째, 향후 PMSCs제도가 활용되고 질적인 전문성을 구축하기 위해서는 정기적인 대테러 교육을 시킬 수 있는 교육 기관을 설치해야 한다. 넷째, 위험지역 출국자에 대해서는 대테러 교육을 제도적으로 의무화시키도록 해야 한다. 다섯째, 대테러 활동을 적합하게 수행해 낼 수 있는 PMSCs를 선정하기 위해서는 엄격한 선발과정을 마련할 수 있는 제도를 모색해야 한다. The counter-terrorism in Korea should be approached practically divided both internally and externally. However, in reality it is impossible for the military and the police to control all the counter-terrorism. So there is a need of precaution using the partnership with private companies. But the military and the police have stressed the conservative and closed operation. Furthermore, the focus of counter-terrorism in Korea is more on expose facto treatment than prevention, so they are almost the defenseless. In order to solve this problem, we should form the private subcontractors of the counter-terrorism experts. That is the introduction and the application of PMSCs system. First, the military and the police need to change its mind set for the partnership with private companies to prepare appropriateness. Second, it should be built up infrastructure to let the hands-up workers on counter-terrorism out place. Third, it should be set up the institutions of learning to train regularly to applicate PMSCs system and to specialize. Fourth, the training of counter-terrorism should be made it mandatory about exit passengers to danger zone. Fifth, the selection of PMSCs suitable for counter-terrorism should be strict.