Converting Weak Neutralizing Antibody against SARS-CoV-2 into Potent Antiviral Using Fc-binding Nanodiscs

Soyun CHOI,Jaehyeon Hwang HWANG,Wonbeom PARK,Soomin KIM,SeungJoo KIM,Suhyun KIM,Nayoon CHOI,Eunkhang PARK,Hwanju KIM,Mina KIM,Hyunjoo CHOO,MinKyeom KIM,YeonJin CHO,Dae-Hyuk KWEON 한국생물공학회 2023 한국생물공학회 학술대회 Vol.2023 No.10

Analysis of psychological effects expected from educational pet insect rearing

( Soyun Kim ),( Haechul Park ),( Ingyun Park ),( Kwanho Park ),( Namjung Kim ),( Seonghyun Kim ) 한국잠사학회 2015 International Journal of Industrial Entomology Vol.31 No.1

In an effort to obtain foundational data required to evaluate the therapeutic effect of educational insect rearing, this study surveyed current educational pet insect rearing practices in Korea and examined the expected psychological effects from participating in the activity. Data were collected from those who visited the special insect exhibition in May 2013 using a self-reporting survey. The results indicated that 48.3% of the responders had experienced insect rearing, and that rhino and stag beetles were the most commonly reared insects. Most of the respondents (83.1%) reported they were not currently rearing any insects, which suggested that insect rearing tends to be a one-time experience. Expected psychological effects could be divided into emotional (56.3%) and cognitive (41.8%) effects, and these varied by age and gender. The differences in expected psychological effects were particularly clear between adults and adolescents, the latter of whom were the main participants in the activity. It is therefore necessary to develop standardized manuals and care programs for more diverse insect species with which to help keep up consumer interest in educational insect rearing. These efforts will help champion the psychotherapeutic effects of educational pet insect rearing and enhance its role as a learning aid.

수요자와 공급자 대상 요구조사를 통한 장애인 치과주치의제도의 제안

김소연(SoYun Kim),백혜란(Hye-Ran Paik),진보형(Bo-Hyoung Jin),이재영(Jae-Young Lee),김지현(Jihyun Kim),김영재(Young-Jae Kim) Asia association of Disability and Oral health 2018 International Journal of Disability and Oral Healt Vol.14 No.2

This study proposed a registered dentist model for the disabled based on consumer in-depth interview and supplier survey. This study proposed that dental clinics in the community take role as registered dentists for the disabled. Qualification screening and facility prerequisites are required to be selected as the registered dentists for the disabled and patients of the registered dentists were restricted to the disabled who can cooperate to dental treatment services with or without the aid of physical bondage. In order to encourage the participation in the program, subsidies for the registered dentists were necessary. Also, this study proposed financial supports for the medical expenses for patients at the same level as the current dental care center for the disabled. The registered dentist program for the disabled meets the needs of disabled consumers, such as accessibility of medical institutions, expertise of medical staff, and ongoing treatments with familiar medical staff. The registered dentist program for the disabled is expected to provide prevention and ongoing management for oral health promotion of disabled people and it also contribute to lower economic burden of oral health care of the disabled.

Neurogenic rosacea in Korea

( Hyeone Kim ),( Seokyoung Kang ),( Koeun Kim ),( Soyun Cho ),( Kwangho Kim ),( Il-hwan Kim ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1

Background: Rosacea with severe neurologic symptoms such as burning and stinging is often not effectively treated with conventional therapies. Objectives: The aim of this study was to investigate the clinical characteristics of Korean rosacea patients with prominent neurological symptoms. Methods: In the present study, the demographic features, medical history, clinical manifestations, and treatment modalities of 17 neurogenic rosacea patients that had prominent neurologic symptoms and 106 erythematotelangiectatic rosacea (ETR) patients are investigated as a control group. Results: All seventeen neurogenic rosacea patients had severe persistent erythema with burning/stinging sensation limited to both cheeks. Among these patients, 94.1% were female (16/17), 23.6 % had dyslipidemia (4/17), 17.7 % had hypertension (3/17), and 17.7% had psychiatric diseases. Heat stimuli (58.8 %, [10/17]), and stress (52.9 %, [9/17]) were major aggravating factors. Cold stimuli alleviated the symptoms in half of the patients (41.2 %, [7/17]). Fourteen of seventeen patients (82.3 %) improved after receiving anticonvulsants and antidepressants. Conclusion: Rosacea patients with severe neurologic symptoms show distinct clinical manifestations and should be classified separately, and a different therapeutic approach is necessary for them

Converting a Host Receptor into Sustained Intranasal Virucides against SARS-CoV-2 Using Nanodiscs

Jaehyeon HWANG,Wonbeom PARK,Soomin KIM,SeungJoo KIM,Suhyun KIM,Nayoon CHOI,Eunkhang PARK,Hwanju KIM,Mina KIM,Hyunjoo CHOO,Soyun CHOI,MinKyeom KIM,YeonJin CHO,Dae-Hyuk KWEON 한국생물공학회 2023 한국생물공학회 학술대회 Vol.2023 No.10

The Influence of Self-regulated Learning Strategy on Critical Thinking in the D igital N etw ork Learning Environment

Soyun Kim 한국아세아태평양교육문화융복합학회 2021 Asia Pacific Journal of Teaching and Learning Vol.1 No.2

Purpose: This study considered that the success or failure of online learning depends on the learner's self-regulation ability, and analyzed the effect of self-regulated learning instructional strategies on learners' critical thinking skills in social studies education in a digital network learning environment. Method: The components of self-regulated learning based on the study of Yu & Pintrich(1998), Kauffman (2004) and Boeun Kim(2019), the sub-elements of each strategy are 'rehearsal', 'elaboration', 'organization' for cognitive strategies, 'planning', 'monitoring', 'regulating' for meta-cognitive strategies, and 'mastery goal', 'self-efficacy', and 'task value' for motivational strategies. Critical thinking skills components were presented by reducing them to 4 areas in consideration of overlapping learning topics and components among them presented by Kyung-Chul Huh et al.(1990). Results: The results of the analysis through the pre- and post-test were first, in the case of self-regulated learning ability, the experimental classes showed significant improvement in the overall average of selfregulated learning ability and all sub-factors. Looking at the difference with the comparison classes, there were significant differences in 'rehearsal', 'elaboration', 'organization' for cognitive factors, 'planning', 'regulating' for meta-cognitive factors, and 'self-efficacy' for motivational factors. Second, in the case of critical thinking skills, the average of all and sub-factors, 'claiming opinions with valid and sufficient grounds', 'viewing the problem from various perspectives' showed a significant improvement in the experimental group compared with the non-group. Third, looking at the relationship between selfregulated learning ability and critical thinking skills, among self-regulated learning abilities, metacognitive 'regulating' factors, are related to the entire critical thinking skills and 'claiming opinions with valid and sufficient grounds', 'viewing the problem from various perspectives' and 'choosing reliable information'. Conclusion: meta-cognitive 'regulating' factors Meta-cognitive 'regulating' factors share and compare different learning strategies, and change one's own strategies according to the teacher's feedback. As a result of this study, this meta-cognitive 'regulating' factors has a high correlation with critical thinking function. In particular, meta-cognitive 'regulating' factors had the greatest effect on the 'viewing the problem from various perspectives' factor. This refers to a strategy that attempts to find the most rational solution by correctly understanding the nature and nature of a problem by looking at a problem from various perspectives.

Development of Molecular Markers for Predicting Radish (Raphanus sativus) Flesh Color Based on Polymorphisms in the RsTT8 Gene

Soyun Kim,Man-Ho Oh,Keunho Yun,Ju Young Ahn,Ju Yeon Yang,Hayoung Song,Yoonkang Hur 한국원예학회 2021 한국원예학회 학술발표요지 Vol.2021 No.10

Red radish (Raphanus sativus L.) cultivars are a rich source of health-promoting anthocyanins and are considered a potential source of natural colorants used in the cosmetic industry. However, the development of red radish cultivars via conventional breeding is very difficult, given the unusual inheritance of the anthocyanin accumulation trait in radishes. Therefore, molecular markers linked with radish color are needed to facilitate radish breeding. Here, we characterized the RsTT8 gene isolated from four radish genotypes with different skin and flesh colors. Sequence analysis of RsTT8 revealed a large number of polymorphisms, including insertion/deletions (InDels), single nucleotide polymorphisms (SNPs), and simple sequence repeats (SSRs), between the red-fleshed and white-fleshed radish cultivars. To develop molecular markers on the basis of these polymorphisms for discriminating between radish genotypes with different colored flesh tissues, we designed four primer sets specific to the RsTT8 promoter, InDel, SSR, and WD40/acidic domain (WD/AD), and tested these primers on a diverse collection of radish lines. Except for the SSR-specific primer set, all primer sets successfully discriminated between red-fleshed and white-fleshed radish lines. Thus, we developed three molecular markers that can be efficiently used for breeding red-fleshed radish cultivars.

결절성 황색종과 동반된 제 Ⅲ 형 과지질단백혈증 1예

김지현,김연진,김현주,조소연,황규광,함정희 梨花女子大學校 醫科大學 醫科學硏究所 2000 EMJ (Ewha medical journal) Vol.23 No.1

We report a case of type Ⅲ hyperlipoproteinemia associated with tuberous xanthoma, which is improved by treatment with lovastatin and bezafibrate. A 34-year-old female patient visited our clinic for evaluation of multiple yellowish-brown papulonodules on the kness, elbows and palms. Serum lipid examination showed an abnormal elevation of serum cholesterol and triglyceride. Lipoprotein electrophoresis showed a single peak at pre-β and β portion without separation. The biopsh specimen from a nodule on the knee and a papule on the palm revealed characteristic findings of xanthoma. We diagnosed the case as type Ⅲ hyperlipoprotei-nemia. After 3 months of treatment with diet restriction, lovastatin and bezafibrate, the serum levels of cholesterol and triglyceride were reduced to normal level. The skin lesion of the palm showed complete regression and ones on both knees and elbows were moderate improvement.

Invited Paper Session 3 (IPS 3) : A survey on the knowledge and consumer behavior regarding cosmetics in Koreans visiting dermatology clinic

( Soyun Cho ),( Sohee Oh ),( Nack In Kim ),( Dong Kun Kim ),( Joung Soo Kim ),( Young Suck Ro ),( Young Min Park ),( Chun Wook Park ),( Dong Won Lee ),( Sang Jun Lee ),( Weon Ju Lee ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2

Background: Cosmetics can affect the skin condition profoundly, and yet no survey has been performed in Koreans visiting dermatology clinics. Objectives: To assess knowledge and consumer behavior regarding cosmetics in Koreans visiting dermatology clinics. Methods: A questionnaire consisting of 43 questions concerning demographics, use/knowledge/ selection/ purchase of cosmetics was given to patients and accompanying persons who visited dermatologic clinics in university and private clinic settings. Results: In total 1,015 subjects (73.2% female, mean age 32.5 years) completed the survey. Education level was college or higher in 72.8%. Thirty-one percent had been diagnosed with a skin disorder, atopic dermatitis and seborrheic dermatitis being the most frequent diagnoses (33.7% and 16.8%, respectively). The frequency of makeup/sunscreen/functional cosmetics use, amount of sunscreen use, recognition of functional cosmetics, and knowledge of shelf life were significantly correlated with level of education. Among functional cosmetics, whitening products were used most frequently (29.2%). Regardless of education level, 79.2% purchased cosmetics without checking ingredients, and 85.7% were unaware of the all-ingredient-labeling regulations, and yet subjects considered ingredient the most important factor when purchasing a product. Conclusion: The demographic, knowledge and behavioral data obtained through this survey could serve as a basis for providing better quality care to our outpatients.

Knowledge and Behavior Regarding Cosmetics in Koreans Visiting Dermatology Clinics

( Soyun Cho ),( Sohee Oh ),( Nack In Kim ),( Young Suck Ro ),( Joung Soo Kim ),( Young Min Park ),( Chun Wook Park ),( Weon Ju Lee ),( Dong Kun Kim ),( Dong Won Lee ),( Sang Jun Lee ) 대한피부과학회 2017 Annals of Dermatology Vol.29 No.2

Background: Cosmetics can affect the skin condition pro-foundly, and yet no survey has been performed in Koreans visiting dermatology clinics. Objective: To assess knowl-edge and consumer behavior regarding cosmetics in Koreans visiting dermatology clinics. Methods: A questionnaire con-sisting of 43 questions concerning demographics and use/knowledge/selection/purchase of cosmetics was given to patients and accompanying persons who visited dermato-logic clinics in university and private clinic settings. Results: In total 1,015 subjects (73.2% females, mean age 32.5 years) completed the survey. Education level was college or higher in 72.8%. Thirty-one percent had been diagnosed with a skin disorder, atopic dermatitis and seborrheic dermatitis being the most frequent diagnoses (33.7% and 16.8%, respect-tively). The frequency of makeup/sunscreen/functional cos-metics use, amount of sunscreen use, recognition of func-tional cosmetics, and knowledge of shelf life were sig-nificantly correlated with level of education. Among “functional cosmetics,” whitening products were used most frequently (29.2%). Regardless of education level, 79.2% purchased cosmetics without checking ingredients, and 85.7% were unaware of the all-ingredient-labelling regu-lations, and yet subjects considered ingredient the most im-portant factor when purchasing a product. Conclusion: Outpatient subjects in their twenties and thirties are the most knowledgeable about cosmetics in Korea. (Ann Dermatol 29(2) 180∼186, 2017)