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The Crystal and Molecular Structure of N1-Cyclohexyl-N2-(o-Chlorobenzal) Imino Thiourea
Chung Hoe Koo,Hojing Kim,Hoon Sup Kim,Chong Whan Chang 대한약학회 1977 약학회지 Vol.21 No.3
N1-Cyclohexyl-N2-(o-chlorobenzal) imino thiourea, C14H18 N3SCl, crystallizes in C2/c, with a=19.68, b=7.74, c=20.42angstrom, beta=92.8o and eight formula units in the unit cell. The structure was solved by the study of Patterson sections, calculated from three-dimensional film data, and was refined by block-diagonal least-squares methods to R=0.16 based on 1288 independent intensity data. The rest atoms of N1-Cyclohexyl-N2-(o-chlorobenzal) imino thiourea molecule excluding cyclohexan ring and chlorine atoms approximately lie on a plane. A pair of molecules related by the symmetry centers are connected directly with the N-H...... S hydrogen bonds. Apart from the hydrogen bonding system the structure is held together by the van der Waals forces.
Chung, Jae-Seung,Son, Nak Hoon,Lee, Sang Eun,Hong, Sung Kyu,Jeong, Chang Wook,Kwak, Cheol,Kim, Hyeon Hoe,Hong, Sung Hoo,Kim, Yong June,Kang, Seok Ho,Chung, Jinsoo,Kwon, Tae Gyun,Hwang, Eu Chang,Byun, The Korean Academy of Medical Sciences 2018 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.33 No.43
<P><B>Background</B></P><P>To examine survival rates and renal function after partial nephrectomy (PN) and radical nephrectomy (RN) in patients with chronic kidney disease (CKD).</P><P><B>Methods</B></P><P>We studied 4,332 patients who underwent PN or RN for pathological T1a-T2N0M0 renal cell carcinoma from 1988 to 2014. Patients were divided into two subgroups of CKD stage I–II and stage III. Kidney function, and survival outcomes were compared between groups.</P><P><B>Results</B></P><P>We included 1,756 patients with CKD I–II and 276 patients with CKD III in the final pair-matched analysis. Kidney function was significantly better preserved in the PN than in the RN group among all patients. However, the beneficial effect of PN on kidney function gradually disappeared over time in CKD III patients. The 5-year overall survival (OS) rates after PN and RN differed in patients with CKD I–II disease (99.4% vs. 96.5%, respectively, <I>P</I> = 0.015). The 5-year OS rates after surgery were not affected by mode of nephrectomy in CKD III patients (97.8% vs. 93.5%, <I>P</I> = 0.103). The 5-year cancer-specific survival rates did not differ between treatment groups in all CKD stage. Cox hazard analysis showed that the operative method was a significant factor for OS in CKD I–II patients (hazard ratio [HR], 0.320; confidence interval [CI], 0.122–0.840; <I>P</I> = 0.021). However, PN was not beneficial in terms of OS in CKD III patients (HR, 0.395; CI, 0.086–1.172; <I>P</I> = 0.117).</P><P><B>Conclusion</B></P><P>PN is associated with a higher OS rate and better kidney function in patients with preoperative CKD stage I and II, but not in those with CKD stage III.</P>
임지훈(Jee-Hoon Lim),김창수(Chang-Su Kim),정회경(Soo-Young Oh),오수영(Moon-Young Chung),정문영(Hoe-Kyung Jung) 한국정보과학회 2002 한국정보과학회 학술발표논문집 Vol.29 No.1A
인터넷/웹 비즈니스의 확산과 더불어, 기업간(B2B) 거래 처리에도 혁명적인 변화가 일어나고 있다. 그러나, 이러한 변화의 이면에는 해결해야 할 많은 기술적인 제약이 내포되어 있다. 무엇보다도, 전자적인 기업간 거래 처리를 위해서는 컴퓨터 시스템간에 구조화된 정보를 교환할 수 있도록 공동의 언어가 제공되어야 한다. 이런 공동의 언어에 대한 문제를 해결하기 위해서 UN/CEFACT와 OASIS에서는 XML(eXtensible Markup Language)을 기반으로 한 ebXML(electronic business XML)을 차세대 e-비즈니스의 표준으로 제정하고 공동 개발하기로 함에 따라 전서계 단일 전자상거래시장 구축이 XML 기반으로 이루어 질 수 있게 되었다. 이에 본 논문에서는 ebXML 도큐먼트 편집을 위해 XML을 기반으로 한 e-business 문서 생성을 위한 XML 편집기, XML DTD 생성기, XML Schema를 작성하기 위한 Schema 편집기 등의 통합 ebXML 문서 편집 시스템을 설계 및 구현 하였다.