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젊은 남자에게 발생한 통상성 간질성 폐렴과 동반된 폐암 1예
박종숙,이준혁,박성우,장안수,박춘식,박재성,백상현,고은석,신화균 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2
Usual interstitial pneumonia(UIP) is relatively rare disease of lung parenchyme under the age of 50. Lung cancer is reported to occur as a complication of UIP, but has not been reported in young age patient with UIP in Korea. A 35-year-old man was admitted to the hospital because of dyspnea, cough and mild fever. He had been suffered from dyspnea during 3 years. The dyspnea worsened recent 1 month ago. He had been treated with pneumonia at another hospital during 4 months before this admission. Chest radiographs and High resolution CT showed subpleural and basal dominant reticular opacities in both lung with no change until now. He was smoker and his occupation was car engine-man dealing with benzene. UIP is suspected by history and radiologic findings. Operation for open lung biopsy was performed to obtain lung specimen via video-assisted thoracoscopic surgery. Patient's pathologic examination showed UIP combined with adenocarcinoma in RLL superior segment and posterobasal segment and RLL lobectomy was done. After operation, the patient has been in cancer free condition so far. We report a case of UIP combined with lung cancer in young man with brief review of the literature.
Current Understanding of $Mycobacterium$ $abscessus$ Infection
Choi, Go-Eun,Jo, Young-Suk,Shin, Sung-Jae 대한미생물학회 2012 Journal of Bacteriology and Virology Vol.42 No.1
$Mycobacterium$ $abscessus$ belongs to a group of rapidly growing mycobacteria (RGM) that cause a broad spectrum of infections in humans. In addition, the association of $M.$ $abscessus$ with the cause of community- and hospital-acquired infections has been recently reported. In fact, $M.$ $abscessus$ is known to be the most drug-resistant mycobacterium and naturally resistant to first-line anti-tuberculous drugs, resulting in the limited therapeutic options and a high failure rate of treatment response. Three closely related species; $M.$ $abscessus$ ($sensu$ $stricto$), $M.$ $bolletii$, and $M.$ $massiliense$ are currently identified however, consensus on the naming of $M.$ $abscessus$-related species has not been made to date. We herein discuss the advanced understanding of the virulence potentials and pathophysiological features of $M.$ $abscessus$ to establish novel therapeutic strategies for $M.$ $abscessus$ infection.
Go, Kang Seok,Lim, Suk Hyun,Kim, Yong Ku,Kwon, Eun Hee,Nho, Nam Sun Elsevier 2018 CATALYSIS TODAY - Vol.305 No.-
<P><B>Abstract</B></P> <P>This study investigated the characteristics of slurry-phase hydrocracking of vacuum residue (VR >524°C) at a high conversion (40–95wt.%) with a change of reaction temperatures and concentrations of the dispersed molybdenum (Mo Conc. 100–2000wt.ppm) catalyst. Experiments were carried out with an initial hydrogen pressure of 80bar (at 80°C) at a reaction temperature from 385 to 440°C for four hours in a batch reactor. As results, it was found that the sediment formation is mainly dependent on the VR conversion by the reaction temperature and started over 70wt.% of VR conversion. Up to 70–80wt.% of VR conversion, the higher catalysts showed the higher asphaltene conversion and prevented the sediment formation at the boundary of its formation, but it didn’t show any effect over 80wt.% of VR conversion anymore. Based on the analysis of the structural change and ξ-potential of asphaltene from the liquid and sediment, and SARA compositional change in the liquid, the reason for sediment formation was explained.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Sediment formation started to form at near 70wt.% VR conversion. </LI> <LI> Higher concentration of catalyst delayed sediment formation. </LI> <LI> Change of resin content in the maltene was found to be significant to form sediment. </LI> <LI> ξ-potential showed the colloidal instability of asphaltene during SHC reaction. </LI> </UL> </P>