개의 질병에 사용된 동아시아 전통의학 처방 연구

박상영 ( Sang Young Park ),오준호 ( Jun Ho Oh ) 대전대학교 한의학연구소 2013 혜화의학회지 Vol.22 No.1

Objective: Today, the public concern for ``Companion Animal" as a family member is ever increasing. Accordingly, the cases of traditional veterinary medicine treatment targeting a companion animal has been increasing, but the traditional records in literature about this have hardly ever been introduced to academic circles. Hereupon, this writing is intending to collect the prescriptions, which were once used for treating canine diseases, in order to report them to academic circles first. Method: This writing recorded the information about canine diseases and their treatment from the books related to the orthodox oriental medicine in East Asia, and analyzed their meanings. Result: Intial records about canine diseases are found in East Asian traditional medicine books including 『 Bonchoseubyu』(741), 『Ilwhajajegaboncho』(unidentifiable period), 『Jeungryuboncho』(1082), etc. The disease perceived by humans at that time was "gwa"(a boil) which is a kind of skin ailments. In addition, these medicine books show that people at that time concentrated on the value of use of a dog as meat rather than a pain of a dog``s diseases. 『Hwalsujaju』(1873)which was established during the Qing Dynasty leaves the most abundant data on canine diseases. This book perceived a dog as a precious existence watching over human housing and property, according to which, canine diseases and treatment methods are subdivided. The prescriptions for a dog`s disease in our country are identifiable only in 『Jeungbodanbangshinpyeon』(1913)과 『 Bijeongmanbyeongtongchibeop』(1933). These books include the prescriptions not only for a dog`s disease but also for a disease of a cow, horse, sheep, chicken, and pig, etc. which are familiar to us. Conclusion: The prescriptions used for a dog in East Asia were different from those for people. It was found that they used a medicine noticeably for external application for easy treatment, and in case of the use of an internal medicine, they adopted a method of getting dogs to take a medicine mixed with rice or porridge for dogs. Such a clue will be applied to the traditional- medicine-based treatment of a companion animal for the time to come.

집체(集體)의 가축을 위한 침술의 과학: 마오쩌둥 시기 중수의학의 탄생, 1956-1963

이종식 ( Jongsik Christian Yi ) 한국과학사학회 2021 한국과학사학회지 Vol.43 No.1

This article explores Maoist China’s project of the “Integration of Chinese and Western Veterinary Medicines,” focusing on how folk veterinary knowledge and practices were “scientized” and transformed into a new hybrid science called “Traditional Chinese Veterinary Medicine” in 1956-1963. Engaging with the literature on socialist science and the PRC history, it shows that a group of Western-trained veterinary scientists, veterinary cadres, and folk veterinary masters, or “TCVM pioneers,” rather than the CCP itself, took a proactive role in this project. I also examine similarities and differences between the construction of TCM and that of TCVM, arguing that the demand that TCVM as an empirical, applied science must serve the socialist collective agriculture shaped the latter in a distinctive way. This article emphasizes that TCVM’s therapeutic efficacy was “scientifically” verified through a particular experimental design that embraced both “Chinese” and “Western” elements. These findings urge us to see the history of science in socialist China without normalizing the Eurocentric and “diffusionist” narrative nor propagating the Sinocentric and Han nationalistic counternarrative. In this vein, this case study provides a way of understanding the “scientific,” “Chinese,” “modern,” and “traditional” in the framework of global history of science.

Stem Cell Therapy Status in Veterinary Medicine

양우종,이수정,윤제원,이정익 한국조직공학과 재생의학회 2015 조직공학과 재생의학 Vol.12 No.4

The stem cell therapy in veterinary medicine continues to grow both experimentally and clinically. Application of adipose-derived mesenchymal stem cell (MSC), umbilical cord blood-derived MSC, bone marrow-derived MSC and skeletal muscle-derived MSC for treatment of various diseases are currently in use for several species. However, the differential efficacies of various approaches are still being investigated. In stem cell therapy, common disease animal models include mouse, rat, rabbit, swine, canine, caprine, equine and dolphin are used. Whereas for clinical models, canine, equine are dolphin are used. We need attention and participation from the researchers of tissue engineering and regenerative medicine, and now it is necessary to develop mutual understanding and cooperation between veterinary and human medicine fields. This review is focused on some of the recent status of stem cell therapy in the veterinary medicine.

한국전쟁기 의료지원 연구: 미 제8군 육군이동외과병원의 활동을 중심으로

한봉석 연세대학교 의학사연구소 2021 연세의사학 Vol.24 No.1

During the Korean War, medical support flooded from various countries and agencies, including the United States. However, this form of medical support was often summarized in the overall support of important participating countries, or its impact was assessed only in a few known cases. Thus, in the development of Korean medical history, the history of the 1950s and the implications of war were often not considered. In this paper, we would like to examine the medical support provided by the 8th U.S. Army during the Korean War—the military doctors, the composition and function of medical personnel, and the Mobile Army Surgical Hospital (MASH). First, during the Korean War, the U.S. military did not have enough military doctors to send to Korea. Therefore, the U.S. military recruited more civilian doctors from the US mainland, and by the late 1950s, it was able to secure enough of them. The 8th Army had also continued its research on preventive medicine, veterinary medicine, and dentistry after the war, based mainly on its experience in mainland Japan. It was in the late 1950s, during the Korean War, that medical support by the 8th Army began in earnest. Second, surgical hospitals, evacuation hospitals, and troops supporting evacuation were at the heart of the 8th Army's military operation. However, other fields, such as veterinary medicine, dentistry, preventive medicine, ophthalmology, orthopedics, and psychiatry, were also connected. However, the medical support of the 8th U.S. Army was provided mainly for combatants, and the recipients were differentiated in the order of Americans, North Korean POWs, and Koreans. Third, the existence of MASH had a huge impact on the Korean medical community. Designed during World War II, the Mobile Surgical Hospital, which was put into full swing during the Korean War, was a place to visually witness the advanced medical care of the United States at that time. It was well known throughout the divisions and roles of mobile surgery hospitals that various advanced technologies for neurosurgery, anesthesia, psychiatry, and blood transfusions were utilized. However, this does not reveal the full extent of medical assistance under the U.S. military. International organizations, including United Nations Korean Reconstruction Agency (UNKRA), paid more attention to the "post-traumatic syndrome" of soldiers under treatment and paid more attention to rehabilitation medicine. Therefore, the nature of medical support during the Korean War will be more detailed and divided by subject and context, which can, then, be analyzed. In addition, with the participation of various subjects, including foreign private aid organizations, the contents and effects of medical support during the Korean War can be discussed in more detail.

반려동물의 표적치료제에 대한 고찰

윤소라(Sorah Yoon) 한국동물보건학회 2023 한국동물보건학회지 Vol.2 No.4

Advances in bioinformatics using next-generation sequencing have dramatically identified new molecules involved in the pathogenesis of various diseases. As a result, many molecularly targeted therapeutics have been developed in medicine including veterinary medicine. In the field of veterinary medicine, toceranib, a multikinase inhibitor was approved 2009 following masitinib, which was the first molecularly target drug approved in 2008. Toceranib is originally approved as a treatment for mast cell tumors, but has been shown to be effective in other tumors as well. Therefore, there is a lot of potential for approved anti-cancer drugs to be used to treat other another type of diseases such as neurodegenerative diseases. Immunotherapies and cancer vaccine are also emerging as targeted therapeutics. In this review, we will discuss the approved molecularly targeted drugs and high potential drugs currently in clinical trials.

조선시대 가축전염병 -개념, 발생 양상 및 방역을 중심으로-

천명선 ( Myung Sun Chun ) 한국농업사학회 2014 농업사연구 Vol.13 No.2

The aim of this study was to analyse the concept of Yeok (epidemic disease) and its outbreaks, diagnosis, etiology, treatment and prevention in the traditional veterinary medicine. The term of U Yeok (infectious disease of cattle) implied unusual outbreaks of endemic or epidemic disease of cattle, which did not distinguish the causes of diseases. Inferring from the epizootic statistics of the early 20th century in Korea, rinderpest, anthrax, blackleg and Foot and mouth disease could be taken in consideration under the term U Yeok. In the veterinary classics the Yeok was differentiated with the terms of On Yeok (infectious disease), Chang Yeok (pestilence), Si Yeok (seasonal epidemics) and Chol Yeok (acute epidemics). In Korea, U Yeok was prevalent throughout the 15-18th centuries. Specifically U Yeok in the 17th century was supposed to have been ‘rinderpest’by the evidence of historical documents, such as rapid spread, seasonal characteristics, simulataneous outbreak with cattle epidemics in Japan. Incidence rate and propotional mortality or case fatility were hard to estimate due to the unaccurate or viased date from the historical documents. It was believed that epidemic diseases were caused by broken macroscopic balance due to the evil spirit, irregular weather change, change of Qi, unclean environment, and overcrowding. Historical documents often reported simultaneous outbreaks of human and animal epidemics after unexpected climate change which could influence Qi of the earth ruling agriculture. Controling and preventing epizootic diseases were considered as the virtue of loving living-beings and benevolent government in the Middle Age in Korea. Epizootic policies were focused on preserving draft animal power and sustaing food supply for people. For treatment of illness, recovering the balance and function of the body of an individual was considered to be is more important than establishing a standard treatment for a specific disease. Therefore herbs and minerals were used to alleviate symptomes of fever, nasal discharge, or anorexia to the infected animals.

반려동물애호가 대상 동물의약품 사용 및 동물약국 이용 현황 조사

안화영,김현지,허지선,여승언,김유환,천영주,임성실,Ahn, Hwa Young,Kim, Hyun Ji,Heo, Ji Seon,Yeo, Seung Eun,Kim, Yu Hwan,Cheon, Young Ju,Lim, Sung Cil 한국임상약학회 2022 한국임상약학회지 Vol.32 No.1

Background: In modern society, the number of households raising companion animals increases, and the market for veterinary medicines is expanding even more. This study aims to investigate the perception of companion animal lovers' veterinary medicines, the necessity of specific guidance by pharmacists for veterinary medicines, the role of pharmacists at veterinary pharmacies, and ways to fulfill that role. Methods: This study evaluated veterinary medicines and medication guidance through Google online questionnaire targeting pet-lovers from December 20, 2021, until January 19, 2022. The questions consist of 1) characteristics of petlovers, 2) purchase history and drug recognition of veterinary drugs, 3) use of veterinary vaccines, 4) use of diagnostic kits, and 5) guidance of veterinary medicines by local pharmacists. Results: The respondents' experience purchasing veterinary drugs was as high as 94.4%. The most purchased drug was heartworm-preventing products, and vaccination was performed mainly at veterinary clinics (veterinarians). The respondents primarily purchased veterinary medicines for companion animals at veterinary hospitals and did not know the name of the drugs which they bought. In addition, respondents expected to receive specific information on veterinary medicines from pharmacists. Conclusion: As the number of veterinary pharmacies in the community will increase with the expansion of the companion animal market, pharmacists should play their role as experts in veterinary medicines through systematic and continuous professional education.

National post-market surveillance assessment of veterinary medicines in Korea during 2018-2021

HyunYoung Chae,Cho-Yeon Lee,HaeChul Park,HyeSook Lee,Byoung-Gon Jeong,Ok-Mi Jeong,Moon Her,JeongWoo Kang 한국예방수의학회 2022 예방수의학회지 Vol.46 No.4

Veterinary medicines have been widely used for disease protection, growth promotion, and feed efficacy development of animals. Along with development of livestock and pet industry, veterinary medicine market in Korea has increased up to 1 billion US dollar in 2021. The national post-market surveillance (NMS) assessment is important system to manage quality control of veterinary medicines that have reached the open market in Korea. In this study, post marketed veterinary medicines have been analyzed particularly for the active ingredient contents based on the rule, “Tips on animal pharmaceutical audit” and monitored the noncomplicant compounds for prevention of adverse drug event. 6,620 veterinray medicines were chosen by NVRQS-SE10-V1 software program which we developed annually in Korea during 2018-2021. The programe chooses veterinary medicines which is 70% were selected products with high sales in order, 20% were selected products with low sales randomly and 10% were noncompliant product from last year automatically, as we input year`s sales and noncompliant product data. The Animal and Plant Quarantine Agency (APQA) leads collection of veterinary medicines from manufacturing companies, drug stores, and hospitals. The NMS assay was analyzed particularly for the active ingredient ingredients performed using liquid and gas chromatography, titration, UV/Vis spectrophometer, pH, and bioassay in Korea Animal Health Production Association (KAHPA). A total of 129 cases were deemed noncompliant and the average noncompliance rate for veterinray medicines was 1.9%. Among noncompliant products violating regulations, the leading cause was insufficient quantity of major ingredients. The compounds found to be noncompliant most frequently were tylosin, spiramycin, ampicillin, amoxicillin and colistin, respectively In this study, we analyzed the results of post marketing surveillance assay from 2018 to 2021 particularly violation rate and pattern. The overall trend indicated gradually decreasing noncompliance rate from 2.7% to 1.6%, suggesting that the quality of veterinary medicines has improved according to the steadily NMS assay and settlement of Korea Veterinary Good Manufacturing Practice (KVGMP) system.

Post-market surveillance assay of veterinary medicines in Korea during 2009∼2012

( Kwang Jick Lee ),( Jeong Woo Kang ),( Sung Won Park ),( Jae Jo Kim ),( Seong Joon Joh ),( Heui Jin Kim ),( Meung Ju Chae ),( Soon Ok Jee ),( Seon Jong Yun ),( Byung Jae So ) 한국예방수의학회 2013 예방수의학회지 Vol.37 No.3

As veterinary medicine industry has grown up steadily, the government quality control of veterinary medicine in market has been performed since 1964. The result of post-market surveillance assay from 2009 to 2012 was analyzed in this study. The average violation rate of all veterinary medicines, was 3.2%, 2.8%, 2.8% and 1.4% in 2009, 2010, 2011 and 2012, respectively. The total average violation rate in the category of antibiotics, other drugs except antibiotics, biologics were 1.2%, 4.4% and 0.8%, respectively. The violations due to insufficiency of major active ingredient content occupied 76.7% among the total violations. The most frequent violated in antibiotics were ampicillin and tylosin, followed by sulfonamides, penicillins etc. In case of other drugs except antibiotics, vitamin A and glucocorticoids (dexamethasone and prednisolone) were violated frequently. The overall trend of violation rates gradually decreased from 2009 to 2012, suggesting that quality of veterinary medicines has improved according to Korea Veterinary Good Manufacturing Practice (KVGMP) system settled down in 1988.

Post-market surveillance assay of veterinary medicines in Korea during 2009∼2012

이광직,강정우,박성원,김재조,조성준,김희진,채명주,이순옥,윤선종,소병재 한국예방수의학회 2013 예방수의학회지 Vol.37 No.3

As veterinary medicine industry has grown up steadily, the government quality control of veterinary medicine in market has been performed since 1964. The result of post-market surveillance assay from 2009 to 2012 was analyzed in this study. The average violation rate of all veterinary medicines, was 3.2%, 2.8%, 2.8% and 1.4% in 2009, 2010, 2011 and 2012, respectively. The total average violation rate in the category of antibiotics, other drugs except antibiotics, biologics were 4.4%, 1.2% and 0.7%, respectively. The violations due to insufficiency of major active ingredient content occupied 76.7% among the total violations. The most frequent violated in antibiotics were ampicillin and tylosin, followed by sulfonamides, penicillins etc. In case of other drugs except antibiotics, vitamin A and glucocorticoids (dexamethasone and prednisolone) were violated frequently. The overall trend of violation rates gradually decreased from 2009 to 2012, suggesting that quality of veterinary medicines has improved according to Korea Veterinary Good Manufacturing Practice (KVGMP) system settled down in 1988.