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A Case of Hypopyon after Repeated Transplantation of Human Amniotic Membrane on the Cornea
Lee, Joong Won,Lee, Yong Kil,Seo, Eok Su 東國大學校醫學硏究所 2007 東國醫學 Vol.14 No.1
We report a case of amniotic membrane transplantation rejection that occurred after the amniotic membrane from the same donor during the treatment of an infectious corneal ulcer. The patient was hospitalized due to continuous foreign body sensation and ocular pain still remaining after the foreign body was removed. After the corneal ulcer was diagnosed, topical antibiotics were applied for ten days. Due to the continued existence of an epithelial defect, the patient was given an amniotic membrane transplant. However, the treatment failed, we performed amniotic membrane retransplantion. After the retransplantation of amniotic membrane, hypopyon was discovered and responded to topical and systemic steroids. We experienced a case of rejection of amniotic membrane transplantation for infected corneal ulcer, which occurs when transplanting amnion that was obtained from the same donor. It is considered necessary to recognize that rejection may occur during amniotic membrane retransplantation if the amnion is from the same donor. 감염성 각막 궤양의 치료로 시행한 양막 이식의 실패로, 같은 공여자의 것으로 시행한 반복된 양막 이식 후 발생한 양막 이식 거부 반응 1예를 경험하여 보고하고자 한다. 46세 남자 환자가 3일전 우안 각막 이물 제거 후 지속된 이물감과 안통을 주소로 내원하였다. 각막 궤양 진단 하에 10일 간 점안 항생제를 사용하였으나 지속된 상피 결손으로 양막 이식을 시행하였고, 그 후 점안 항생제 사용을 자가 정지하여 상피 결손이 지속되어서 첫 번째 양막 이식을 시행하였으나 실패하여, 양막 이식을 재시행하였다. 양막 이식 재시행 후 전방 축농이 관찰 되었고 이를 양막 이식 거부 반응에 의한 것이라 생각하여 전신적, 국소적 스테로이드 치료를 하였고 그에 반응하는 것을 확인하여 양막 이식 거부 반응을 진단하였다. 동일인에게 공여 받은 양막의 재이식 시 일어나는 양막 이식 거부 반응 1예를 경험하였으며 양막 재이식 시 거부 반응이 있을 수 있으며 거부 반응 시 전신적, 국소적 스테로이드 치료가 필요함을 알아야 하겠다.
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배현아 영남대학교 법학연구소 2010 영남법학 Vol.0 No.30
Each country has its own unique culture, governmental system, social mores and economic systems. Korea is beginning on the path of developing donation and transplant systems or cornea and eye bank. We should focus the efforts and resources on achieving a system that can fit into and work successfully within our capacity. The first step should be governmental support of a national system for each area such as organ, tissue and eye as each require singular and specific attention as well as development. National Governmental recognition of a Eye Bank System with a Korean Network for Organ Sharing working with many regional sites would provide the strong foundation needed on which to build a long lasting sersite to the korean people. This type of system is completely transparent, allows for full governmental oversigyp and regulation, promg es partitipation of transplanting surgeons as they take an active role in its operations, promotes full compliance of hospitals in their participation of reporting deaths and provides a secure and trusted system for the people of Korea to support and benefit from its services. I recommend such legislative changes to be considered in Korea where corneal tissue shortage is delaying the availability of corneal transplnat surgery.
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김종민,김종열,김황민,장세웅,정인성,최석화 한국임상수의학회 2015 한국임상수의학회지 Vol.32 No.4
When severely large corneal perforation occurs, penetrating keratoplasty is a treatment of choice alternative to enucleation. A twelve-year-old male Shih Tzu was referred with perforated corneal ulcer secondary to keratoconjunctivitis sicca (KCS). Perforated cornea was directly sutured using 10-0 non-absorbable suture material, and rotational conjunctival flap was performed. However, re-perforation of cornea by wound dehiscence was observed at 1 month after operation. The yellowish lens escaped outside the orbit during corneal re-perforation, the diagnosis was re-perforated corneal ulcer, moderate corneal edema, moderate KCS (STT; 6 mm) and endophthalmitis caused by escaped lens outside orbit. Accordingly, penetrating keratoplasty (PK) and evisceration through corneal recipient site and intrascleral silicone ball prosthesis were carried out as the planned treatment, and resulted in good cosmetic improvement compared to enucliation. However, exposure of silicone ball occurred at the 9 months after the surgery due to the irritation of implant, thus enucleation was performed. In perforated large corneal ulcer with severe intraocular damage, evisceration with silicone ball insertion with PK would be alternative treatment choice to improve the cosmetic appearance.
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박세진 ( Se Jin Park ),변정림 ( Jung Lim Byun ),이상택 ( Sang Taek Lee ),신기철 ( Ki Cheol Shin ),김민희 ( Min Hee Kim ) 대한주산의학회 2007 Perinatology Vol.18 No.3
Peters` anomaly is a rare form of anterior segment dysgenesis in which abnormal cleavage of the anterior chamber occurs. It is defined as a congenital central corneal opacity with corresponding defects in the posterior corneal stroma, Descemet`s membrane, and endothelium. Peters` anomaly may be associated with other ocular or systemic abnormalities like microphthalmos, colobomata, retinal and optic nerve dysplasia, developmental delay, central nervous system defects, craniofacial abnormalities, seizure disorders, genitourinary malformations, and cardiopulmonary defects. Peters` anomaly may also have an inherited pattern, mostly autosomal recessive and dominant inheritance. Mutations involve the PAX6 gene, RIEGI gene, and other genes. Management of infants with congenital corneal opacity is quite difficult, but penetrating keratoplasty is known as the effective treatment for visual outcome if it is performed within the first 3 months of life. We recently experienced a case of Peters` anomaly in association with atrial septal defect & chromosomal abnormality, therefore herein present it with a brief review of relevant literature.
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