Operating Range Scheduled Robust Dahlin Algorithm to Typical Industrial Process with Input Constraint

Xiaoying Tian,Hui Peng,Xuguang Luo,Shiyuan Nie,Feng Zhou,Xiaoyan Peng 제어·로봇·시스템학회 2020 International Journal of Control, Automation, and Vol.18 No.4

There is a class of typical nonlinear industrial process, which can be characterized by a first-order inertia plus pure delay model in an operating range, but the model parameters are different in different operating ranges. Usually, a set of Proportion Integration Differentiation (PID) controllers may be used to control the process, and the controllers have different parameters in different operating areas. However, the adjustment process of the PID controllers’ parameters is not an easy job in practice, and the control performance may also be not perfect. The Dahlin algorithm may provide very good control performance for the process, but its control performance may become very poor if the model parameters are not accurate and/or the input is constrained. Faced with this issue, this paper proposes an Operating-Range Scheduled Robust Dahlin Algorithm (ORSRDA) for the process control with input constraint, which is designed on the basis of a nominal first-order inertia plus pure delay model and the given parameters uncertainty. The process operating ranges are divided into pre-designed several zones accordingto the difference between output setting value and current output when a new setting appears. For each operating range, the parameters of ORSRDA are obtained by solving a min-max problem offline to guarantee the closedloop system’s robust stability and acquire the best step-response control performance. To eliminate the steady state error, the integration control action is added into the ORSRDA when the system output is close to its setting value. The proposed method is applied to temperature control of an experimental electric furnace to demonstrate its effectiveness and implement procedure.

Semantic Role Labeling Based Event Argument Identification

Wen Zhou,Yajun Zhang,Xiaoying Su,Yao Li,Zongtian Liu 보안공학연구지원센터 2016 International Journal of Database Theory and Appli Vol.9 No.6

Event extraction is one of the most challenging tasks of information extraction from text. This paper studies one of the stages of Chinese event extraction, namely, event argument identification. A new method we call Semantic Role Labeling Based Event Argument Identification, based on the state-of-the-art methods of event extraction and event argument identification, is proposed. First, the 5W1H (who, what, whom, when, where, how) information is extracted from the text using semantic role labeling; thereafter, the 5W1H information is mapped to each argument of the event by heuristic rules. The method is used to identify the event arguments on two test sets of acquisition and transfer data, and contrasted with the methods of SRL and SRL combining heuristic rules. We find the best F1 measures for each to be 76.04% and 79.19% respectively.

Heterologous Expression of a Gibberellin 2-Oxidase Gene from Arabidopsis thaliana Enhanced the Photosynthesis Capacity in Brassica napus L.

Bo Zhou,Dan Peng,Jianzhong Lin,Xingqun Huang,Wusheng Peng,Reqing He,Ming Guo,Dongying Tang,Xiaoying Zhao,Xuanming Liu 한국식물학회 2011 Journal of Plant Biology Vol.54 No.1

Gibberellins (GAs) are endogenous hormones that play an important role in regulating plant stature by increasing cell division and promoting seed germination. The GA2-oxidase gene from Arabidopsis thaliana (AtGA2ox8) was introduced into Brassica napus L. by Agrobacterium-mediated floral-dip transformation with the aim of decreasing the amount of bioactive GA and hence reduced the plant height. As anticipated, the transgenic plant exhibited dwarf phenotype. Importantly, compared with the wild type, the transgenic plants had delayed the seed germination, increased the chlorophyll content (28.7–36.3%) and photosynthesis capacity (14.3–18.7%) in a single leaf. At the same time, the photosynthesis capacity of the whole plants was significantly enhanced (35.7–48.6%) due to the extra leaves and branches.

Can in situ liquid SIMS provide enough signals for biology and energy research?

Yufan ZHOU,Yuanzhao DING,Jiachao YU,Xin HUA,James EVANS,Xiaofei YU,David LAO,Xiaoying YU,Zihua ZHU 한국진공학회 2016 한국진공학회 학술발표회초록집 Vol.2016 No.8

The mutation of Scenedesmus obliquus grown in municipal wastewater by laser combined with ultraviolet

Xu Zhou,Wenbiao Jin,Song-fang Han,Xiaoye Li,Shu-Hong Gao,Chuan Chen,Guo-jun Xie,Renjie Tu,Qing Wang,Qilin Wang 한국화학공학회 2019 Korean Journal of Chemical Engineering Vol.36 No.6

Mutagenetic breeding is an efficient technique for the enhancement of lipid productivity from microalgae. In this study, oil-rich microalga Scenedesmus obliquus were treated by Laser-UV composite mutagenesis. Among the 35 mutant strains, X5 was primely screened. Afterwards, a twice UV mutagenizing was operated on X5, and the optimal mutant strain X5-H13 was obtained. The growth rate, dry weight, lipid yield and lipid content of X5-H13 were 0.698× 107 cells/mL·d, 0.99 g/L, 0.49 g/L and 48.8% while cultivated in municipal wastewater, respectively, which were increased by 45%, 58%, 109% and 32% than the original strain. The results of the subculture of repeated mutant showed that the biomass and lipid content of strain X5-H13 were up to 0.99 g/L and 48.8%. The growth of each generation was stable. Furthermore, the random amplified polymorphic DNA analysis indicated that the mutant strain X5-H13 was different from the starting strain, with their genetic similarity coefficient value of 0.815.

A Novel Method for Estimating State-of-Charge in Power Batteries for Electric Vehicles

Nan Zhang,Yunshan Zhou,Qiang Tian,Xiaoying Liao,Feitie Zhang 한국정밀공학회 2019 International Journal of Precision Engineering and Vol.20 No.5

Estimation of the state-of- charge (SOC) of power batteries has always been the focus of electric vehicle users’ criticism. Accurate SOC is beneficial for extending the mileage of electric vehicles and the life of the battery pack. The key to improving SOC accuracy is to establish its accurate model and combine it with an appropriate estimation algorithm. Based on characterization experiments related to SOC, this paper describes a second-order charge–discharge resistor–capacitor model that can accurately simulate external characteristics of the battery and identify them online. An improved adaptive unscented Kalman filter algorithm based on Sage–Husa is introduced to estimate SOC. The reliability of the algorithm is verified by building a MATLAB/Simulink simulation model. The results show that the improved algorithm displays increased robustness and can quickly converge to the true value; the steady-state error is also within a small range.

Role of soy lecithin combined with soy isoflavone on cerebral blood flow in rats of cognitive impairment and the primary screening of its optimum combination

Li Hongrui,Wang Xianyun,Li Xiaoying,Zhou Xueyang,Wang Xuan,Li Tiantian,Xiao Rong,Xi Yuandi 한국영양학회 2023 Nutrition Research and Practice Vol.17 No.2

BACKGROUND/OBJECTIVES: Soy isoflavone (SIF) and soy lecithin (SL) have beneficial effects on many chronic diseases, including neurodegenerative diseases. Regretfully, there is little evidence to show the combined effects of these soy extractives on the impairment of cognition and abnormal cerebral blood flow (CBF). This study examined the optimal combination dose of SIF + SL to provide evidence for improving CBF and protecting cerebrovascular endothelial cells. MATERIALS/METHODS: In vivo study, SIF50 + SL40, SIF50 + SL80 and SIF50 + SL160 groups were obtained. Morris water maze, laser speckle contrast imaging (LSCI), and hematoxylineosin staining were used to detect learning and memory impairment, CBF, and damage to the cerebrovascular tissue in rat. The 8-hydroxy-2′-deoxyguanosine (8-OHdG) and the oxidized glutathione (GSSG) were detected. The anti-oxidative damage index of superoxide dismutase (SOD) and glutathione (GSH) in the serum of an animal model was also tested. In vitro study, an immortalized mouse brain endothelial cell line (bEND.3 cells) was used to confirm the cerebrovascular endothelial cell protection of SIF + SL. In this study, 50 μM of Gen were used, while the 25, 50, or 100 μM of SL for different incubation times were selected first. The intracellular levels of 8-OHdG, SOD, GSH, and GSSG were also detected in the cells. RESULTS: In vivo study, SIF + SL could increase the target crossing times significantly and shorten the total swimming distance of rats. The CBF in the rats of the SIF50 + SL40 group and SIF50 + SL160 group was enhanced. Pathological changes, such as attenuation of the endothelium in cerebral vessels were much less in the SIF50 + SL40 group and SIF50 + SL160 group. The 8-OHdG was reduced in the SIF50 + SL40 group. The GSSG showed a significant decrease in all SIF + SL pretreatment groups, but the GSH showed an opposite result. SOD was upregulated by SIF + SL pretreatment. Different combinations of Genistein (Gen)+SL, the secondary proof of health benefits found in vivo study, showed they have effective antioxidation and less side reaction on protecting cerebrovascular endothelial cell. SIF50 + SL40 in rats experiment and Gen50 + SL25 in cell test were the optimum joint doses on alleviating cognitive impairment and regulating CBF through protecting cerebrovascular tissue by its antioxidant activity. CONCLUSIONS: SIF+SL could significantly prevent cognitive defect induced by β-Amyloid through regulating CBF. This kind of effect might be attributed to its antioxidant activity on protecting cerebral vessels.

Modelling and Prediction of Stress Relaxation for Thermal Bonded Nonwoven Geotextiles

Shiyuan Sun,Xiaoping Gao,Chunhong Fu,Yudong Zhou,Xiaoying Wei,Jiaxin Li,Yiping Qiu 한국섬유공학회 2020 Fibers and polymers Vol.21 No.7

Stress relaxation experiments were performed on three types of thermal bonded nonwoven geotextiles in this studyto model and predict their stress relaxation behaviors. Four mechanical models, including the standard linear solid mechanicsmodel, Eyring’s model, the modified two-Maxwell-unit model and the modified three-Maxwell-unit model were used topredict stress values for 600 h based on 3 and 90 h experimental relaxation data. Results indicated that Eyring’s model and themodified three-Maxwell-unit model fitted the experimental results better than the other two. Estimation using modified three-Maxwell-unit model seemed to construct an upper bound while that using Eyring’s model form a lower bound for thecorresponding experimental data. In addition, predicted curves were much closer to the experimental curve when equationsof the two models were built with the 90 h experimental data than those data of 3 h. Thus, the prediction capability of the twomodels can be substantially improved by employing the data with longer time. In summary, the combination of the modifiedthree-Maxwell-unit model and Eyring’s model can well forcast the range of actual stress during stress relaxation experimentswith the longer term experimental data.

Ginsenosides Rc, as a novel SIRT6 activator, protects mice against high fat diet induced NAFLD

Zehong Yang,Yuanyuan Yu,Nannan Sun,Limian Zhou,Dong Zhang,HaiXin Chen,Wei Miao,Weihang Gao,Canyang Zhang,Changhui Liu,Xiaoying Yang,Xiaojie Wu,Yong Gao The Korean Society of Ginseng 2023 Journal of Ginseng Research Vol.47 No.3

Background: Hepatic lipid disorder impaired mitochondrial homeostasis and intracellular redox balance, triggering development of non-alcohol fatty liver disease (NAFLD), while effective therapeutic approach remains inadequate. Ginsenosides Rc has been reported to maintain glucose balance in adipose tissue, while its role in regulating lipid metabolism remain vacant. Thus, we investigated the function and mechanism of ginsenosides Rc in defending high fat diet (HFD)-induced NAFLD. Methods: Mice primary hepatocytes (MPHs) challenged with oleic acid & palmitic acid were used to test the effects of ginsenosides Rc on intracellular lipid metabolism. RNAseq and molecular docking study were performed to explore potential targets of ginsenosides Rc in defending lipid deposition. Wild type and liver specific sirtuin 6 (SIRT6, 50721) deficient mice on HFD for 12 weeks were subjected to different dose of ginsenosides Rc to determine the function and detailed mechanism in vivo. Results: We identified ginsenosides Rc as a novel SIRT6 activator via increasing its expression and deacetylase activity. Ginsenosides Rc defends OA&PA-induced lipid deposition in MPHs and protects mice against HFD-induced metabolic disorder in dosage dependent manner. Ginsenosides Rc (20mg/kg) injection improved glucose intolerance, insulin resistance, oxidative stress and inflammation response in HFD mice. Ginsenosides Rc treatment accelerates peroxisome proliferator activated receptor alpha (PPAR-α, 19013)-mediated fatty acid oxidation in vivo and in vitro. Hepatic specific SIRT6 deletion abolished ginsenoside Rc-derived protective effects against HFD-induced NAFLD. Conclusion: Ginsenosides Rc protects mice against HFD-induced hepatosteatosis by improving PPAR-α-mediated fatty acid oxidation and antioxidant capacity in a SIRT6 dependent manner, and providing a promising strategy for NAFLD.

Inactivation of epithelial sodium ion channel molecules serves as effective diagnostic biomarkers in clear cell renal cell carcinoma

Zheng Qian,Wang Yifang,Zhao Ran,Han Peipei,Zhao Jun,Li Limei,Zhou Xiaohui,Li Ping,Mo Yingxi,Pan Xinli,Luo Wenqi,Zhou Xiaoying 한국유전학회 2023 Genes & Genomics Vol.45 No.7

Background Non-voltage-gated sodium channel, also known as the epithelial sodium channel (ENaC), formed by heteromeric complexes consisting of SCNN1A, SCNN1B, and SCNN1G, is responsible for maintaining sodium ion and body fluid homeostasis in epithelial cells. However, no systematic study of SCNN1 family members has been conducted in renal clear cell carcinoma (ccRCC) to date. Objective To investigate the abnormal expression of SCNN1 family in ccRCC and its potential correlation with clinical parameters. Methods The transcription and protein expression levels of SCNN1 family members in ccRCC were analyzed based on the TCGA database, and were confirmed by quantitative RT-PCR and immunohistochemical staining assays, respectively. The area under curve (AUC) was used to evaluate the diagnostic value of SCNN1 family members for ccRCC patients. Results The mRNA and protein expression of SCNN1 family members was significantly downregulated in ccRCC compared with normal kidney tissues, which might be due to DNA hypermethylation in the promoter region. It is worth noting that the AUC of SCNN1A, SCNN1B, and SCNN1G were 0.965, 0.979, and 0.988 based on the TCGA database (p < 0.0001), respectively. The diagnostic value was even higher when combing these three members together (AUC = 0.997, p < 0.0001). Intriguingly, the mRNA level of SCNN1A was significantly lower in females compared with males, while SCNN1B and SCNN1G were increased with the progression of ccRCC and remarkably associated with a worse outcome for patients. Conclusion The aberrantly decrease of SCNN1 family members might serve as valuable biomarkers for the diagnosis of ccRCC.