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      • The Typical Application of Building Energy Consumption Monitoring and Energy Management : A Case Study

        Liang Zhao,Ruobing Liang,Jili Zhang 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.1

        Building energy consumption monitoring and management system plays a vital role in the advance of building energy conservation, because it offers abundant online real time data, which are mainly used to further analyze energy saving potential and put forward a feasibility methodology for implementation. In addition to its extreme importance in decreasing energy consumption and saving costs, the platform can also help to find the anomalies of the main equipment. In this paper, we first introduce the structure of the monitoring platform, and then put forward an error analysis principle to improve the precision of heat meters. A case study is given for a building in “hot summer and cold winter” area, including the installation of various measuring meters and data verification. Finally, the energy consumption data of the building from January to December in 2013 were analyzed.

      • 8q24 rs4242382 Polymorphism is a Risk Factor for Prostate Cancer among Multi-Ethnic Populations: Evidence from Clinical Detection in China and a Meta-analysis

        Zhao, Cheng-Xiao,Liu, Ming,Xu, Yong,Yang, Kuo,Wei, Dong,Shi, Xiao-Hong,Yang, Fan,Zhang, Yao-Guang,Wang, Xin,Liang, Si-Ying,Zhao, Fan,Zhang, Yu-Rong,Wang, Na-Na,Chen, Xin,Sun, Liang,Zhu, Xiao-Quan,Yuan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.19

        Background: Evidence supporting an association between the 8q24 rs4242382-A polymorphism and prostate cancer (PCa) risk has been reported in North American and Europe populations, though data from Asian populations remain limited. We therefore investigated this association by clinical detection in China, and meta-analysis in Asian, Caucasian and African-American populations. Materials and Methods: Blood samples and clinical information were collected from ethnically Chinese men from Northern China with histologically-confirmed PCa (n=335) and from age-matched normal controls (n=347). The 8q24 (rs4242382) gene polymorphism was genotyped by polymerase chain reaction-high-resolution melting analysis. We initially analyzed the associations between the risk allele and PCa and clinical covariates. A meta-analysis was then performed using genotyping data from a total of 1,793 PCa cases and 1,864 controls from our study and previously published studies in American and European populations, to determine the association between PCa and risk genotype. Results: The incidence of the risk allele was higher in PCa cases than controls (0.222 vs 0.140, $P=7.3{\times}10^{-5}$), suggesting that the 8q24 rs4242382-A polymorphism was associated with PCa risk in Chinese men. The genotypes in subjects were in accordance with a dominant genetic model (ORadj=2.03, 95%CI: 1.42-2.91, $Padj=1.1{\times}10^{-4}$). Presence of the risk allele rs4242382-A at 8q24 was also associated with clinical covariates including age at diagnosis ${\geq}65$ years, prostate specific antigen >10 ng/ml, Gleason score <8, tumor stage and aggressive PCa, compared with the non-risk genotype ($P=4.6{\times}10^{-5}-3.0{\times}10^{-2}$). Meta-analysis confirmed the association between 8q24 rs4242382-A polymorphism and PCa risk (OR=1.62, 95%CI: 1.39-1.88, $P=1.0{\times}10^{-5}$) across Asian, Caucasian and African American populations. Conclusions: The replicated data suggest that the 8q24 rs4242382-A variation might be associated with increased PCa susceptibility in Asian, Caucasian and African American populations. These results imply that this polymorphism may be a useful risk biomarker for PCa in multi-ethnic populations.

      • SCIESCOPUSKCI등재

        Ram semen preserved at 0℃ with soybean lecithin Tris-based extender substituted for egg yolk

        Zhao, Jian-qing,Xiao, Guo-liang,Zhu, Wen-liang,Fang, Di,Li, Na,Han, Chun-mei,Gao, Qing-hua Asian Australasian Association of Animal Productio 2021 Animal Bioscience Vol.34 No.2

        Objective: The present study evaluated the preservation of ram semen at 0℃ using soybean lecithin with a Tris-fructose extender. Methods: Semen was collected by artificial vagina ejaculation from six rams with proven fertility. High quality ejaculates were diluted by soybean lecithin (0.25%, 0.5%, 0.75%, 1.0%, 1.25%) using Tris-fructose extender and control (Tris-fructose egg yolk extender), respectively. The ejaculates were diluted to a concentration of 5×108 sperm/mL, followed by cooling to 0℃ in 90 min and maintaining the temperature for 12 days. The diluted semen samples were examined and recorded for sperm progressive motility, acrosome integrity at 0, 24, 72, 144, 216, 288 h, respectively. Two hundred and twenty-three ewes were inseminated for 216 h with optimal soybean lecithin concentrated semen or control via trans-cervical insemination. Results: The results showed that there were no differences in sperm progressive motility at 0, 24, 72, and 144 h (p>0.05). After 216 h, the sperm progressive motility in the control group and 0.5% concentration groups was significantly higher when compared to 0.25% concentration (p<0.05). The 0.5% concentration group demonstrated the highest survival rate and had no difference with the control group (p>0.05). At 216 h, the sperm progressive motility of all groups was still above 50%. The acrosome integrity of all groups was decreased with prolongation of storage time, but there was no difference at each time point (p>0.05). There was no significant difference in the lambing rate and pregnancy rate between the 0.5% concentration group and the control group (p>0.05). Conclusion: These results suggest that ram sperm is capable of fertilization after preservation at 0℃ with 0.5% of soybean lecithin in Tris-based extender substituted for egg yolk and produce normal offspring after insemination.

      • SCIESCOPUS

        Experimental and Simulation Study of PEMFC based on Ammonia Decomposition Gas as Fuel

        Zhao, Jian Feng,Liang, Yi Fan,Liang, Qian Chaos,Li, Meng Jie,Hu, Jin Yi The Korean Electrochemical Society 2022 Journal of electrochemical science and technology Vol.13 No.1

        Compared with hydrogen, ammonia has the advantages of high gravimetric hydrogen densities (17.8 wt.%), ease of storage and transportation as a chemical hydrogen storage medium, while its application in small-scale on-site hydrogen production scenarios is limited by the need for complex separation equipment during high purity hydrogen production. Therefore, the study of PEMFC, which can directly utilize ammonia decomposition gas, can greatly expand the application of fuel cells. In this paper, the output characteristics, fuel efficiency and the variation trend of hydrogen concentration and local current density in the anode channel of fuel cell with the output voltage of PEMFC fueled by ammonia decomposition gas were studied by experiment and simulation. The results indicate that the maximum output power of the hybrid fuel decreases by 9.6% compared with that of the pure hydrogen fuel at the same inlet hydrogen equivalent. When the molar concentration of hydrogen in the anode channel is less than 0.12, the output characteristics of PEMFC will be seriously affected. Employing ammonia decomposition gas as fuel, the efficiency corresponding to the maximum output power of PEMFC is approximately 47%, which is 10% lower than the maximum efficiency of pure hydrogen.

      • KCI등재

        Characterization of proteinase A excretion from Saccharomyces cerevisiae in high sugar stress conditions

        Liang Dong,Feng Li,Yongzhe Piao,Dong Sun,Rui Zhao,Cheng Li,Lina Cong,Changxin Zhao 한국응용생명화학회 2015 Applied Biological Chemistry (Appl Biol Chem) Vol.58 No.2

        High sugar concentration culturing was commonly used in modern fermentation industry. However, it leads to the reduction of the foam stability in beer brewing due to the excess secretion of proteinase A. To better understand the characterization of proteinase A excretion from Saccharomyces cerevisiae in high sugar stress conditions, the cultures were grown by using YNB medium with a high concentration of glucose. Pro-PrA isolated from the medium was purified by gel exclusion chromatography, and the PrA activity was detected using fluorescent substrate analysis. The relative molecular weight of the purified PrA and pro-PrA was estimated at 42 and 54 kDa, respectively, by SDS-PAGE. It indicated that the metabolic behavior of PrA in the high glucose culturing was quite different from the normal conditions, and glucose concentration may have a big influence on its secreted process. Further study showed that PrA was released at the logarithmic growth phase of the culturing, and the amount of PrA was 11 times higher compared with the normal culturing. PrA was considered to be activated by itself under acidic conditions. And it was also confirmed in this work that the step-wise pathway for the autoactivation known as a pseudo-PrA has a major contribution to the autoactivation process of PrA zymogen outside the cell.

      • A Summary of Multicast Routing Algorithms in Wireless Mesh Networks

        Liang Zhao,Changqing Gong,Xianwei Li,Guolong Chen 보안공학연구지원센터 2015 International Journal of Multimedia and Ubiquitous Vol.10 No.6

        Wireless Mesh Network (WMN) presents us a key emerging technology which can construct the next generation wireless multi-hop network. It combines the advantages of both mobile ad-hoc network (MANET) and traditional fixed network. The applications of WMNs also attract significant industrial and academic attentions. As a vital function of network communication, multicast is normally applied to transmit data for high-definition video and gaming in WMNs. Therefore, the multicast routing algorithms are very important to the performance of group communication in WMNs. In this paper, we review a list of existing multicast routing algorithms in WMNs. Based on the findings, we also point out the open issues of multicast routing algorithms.

      • SCIESCOPUSKCI등재

        HARNACK INEQUALITY FOR A NONLINEAR PARABOLIC EQUATION UNDER GEOMETRIC FLOW

        Zhao, Liang Korean Mathematical Society 2013 대한수학회보 Vol.50 No.5

        In this paper, we obtain some gradient estimates for positive solutions to the following nonlinear parabolic equation $$\frac{{\partial}u}{{\partial}t}={\triangle}u-b(x,t)u^{\sigma}$$ under general geometric flow on complete noncompact manifolds, where 0 < ${\sigma}$ < 1 is a real constant and $b(x,t)$ is a function which is $C^2$ in the $x$-variable and $C^1$ in the$t$-variable. As an application, we get an interesting Harnack inequality.

      • KCI등재

        The infertile individual analysis based on whole-exome sequencing in chinese multi-ethnic groups

        Zhao Qiongzhen,Li Yanqi,Liang Qi,Zhao Jie,Kang Kai,Hou Meiling,Zhang Xin,Du Renqian,Kong Lingyin,Liang Bo,Huang Weidong 한국유전학회 2023 Genes & Genomics Vol.45 No.4

        Background Infertility is a common and rapidly growing health issue around the world. The genetic analysis based on the infertile population is crucial for intervention and treatment. Objective To find candidate gene locus led to azoospermia in Chinese multi-ethnic groups and provide theoretical guidance for the diagnosis of genetic diseases to progressively aggravated infertility patients and sterile offspring with ART. Methods The study based on whole-exome sequencing (WES) was presented for genetic characteristic analysis of multi-ethnics and identification of variants related to infertility in Xinjiang area of China. Results The frequency of pathogenic variants showed significant ethnic differences among four main ethnics in Xinjiang. The population structure analysis confirmed that the Hui was close to the Han population, the Kazak was close to the Uygur population, and there are three ancestry components in the four ethnics. In addition, ten candidate variants potentially regulated azoospermia were detected, and KNTC1 (rs7968222: G > T) was chosen to validate the association. Through the analysis in the valid group, the frequency of rs7968222 (G > T) has a significant difference in the azoospermia population (11.76%, 8/68) and normospermia population (4.63%, 35/756) (P < 0.001). Interestingly, the proportion of people with abnormal follicle-stimulating hormone (FSH) level in the group carrying rs7968222 (G > T) was significantly higher than non-carriers (P < 0.05). Therefore, rs7968222 may regulate spermatogenesis through affecting hormone level. Conclusion Our study establishes the genetics analysis of Northwest China and finds a candidate gene locus KNTC1 (rs7968222: G > T), which is one of the genetic susceptibility factors for male azoospermia.

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