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윤이중(E-Joong Yoon),박경철(Kyoung-Chul Park),서창호(Chang-Ho Seo),류재철(Jae-Cheol Ryou) 한국정보과학회 2001 정보과학회 컴퓨팅의 실제 논문지 Vol.7 No.6
본 논문은 무선 인터넷 기반 시스템을 지원하기 위한 전자 메일 시스템으로 기존의 일반 전자메일의 기능적, 시스템 구성적인 한계점을 극복하기 위한 방안을 제시하고 있다. 이를 위해 기존 메일 시스템의 확장성을 보장하기 위하여 계층적인 구조를 제시하였으며, 실질적으로 무선 단말기와 연동하여 실험해 봄으로써 그 가능성을 제시한다. This paper is a proposal of the world-wide messaging system for supporting wireless internet messaging against the existing system which has many limits on functionality and structure. To this work, this paper proposes the hierarchical structure to ensure an extensibility of an existing messaging system, and show the possibility via implementing and operating together wireless units.
논문 : 생쥐와 HEK 293 신장세포주에서 C.albicans-유도 TNF-α 생산에 관한 Chitosanoligosaccharide의 효과
윤현중 ( Hyun Joong Yoon ),문명이 ( Myoung E Moon ),박행순 ( Haeng Soon Park ),임선영 ( Sun Young Im ),이황희 ( Hwang Hee Blaise Lee ),이준행 ( Jun Haeng Lee ),김종세 ( Jong Se Kim ),노영복 ( Young Bok Noh ),김영호 ( Young Ho K 전남대학교 약품개발연구소 2006 약품개발연구지 Vol.15 No.-
생쥐와 HEK 293 신장세포주에서 C.albicans-유도 TNF-α 생산에 관한 Chitosanoligosaccharide의 효과
윤현중 ( Hyun Joong Yoon ),문명이 ( Myoung E Moon ),박행순 ( Haeng Soon Park ),임선영 ( Sun Young Im ),이황희 ( Hwang Hee Blaise Lee ),이준행 ( Jun Haeng Lee ),김종세 ( Jong Se Kim ),노영복 ( Young Bok Noh ),김영호 ( Young Ho K 한국키틴키토산학회 2006 한국키틴키토산학회지 Vol.11 No.2
( Soo Young Jeong ),( Ji Yoon Ryu ),( Meong-sun Kim ),( Ji Hye Kim ),( E Sun Paik ),( Chel Hun Choi ),( Tae-joong Kim ),( Byoung-gie Kim ),( Duk-soo Bae ),( Jeong-won Lee ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-
Objective: Olaparib, one of the first PARP inhibitors, has been used for maintenance therapy in BRCA-mutant patients with platinum-sensitive, recurrent, high-grade serous ovarian cancer. In acute myeloid leukemia(AML) and breast cancer cells, DNA-demethylating agents, inhibitors of DNA methylation and DNA methyltransferases(DNMTs), increase PARP1 tightly bound into chromatin. The purpose of this study is to confirm anti-cancer effect of combination therapy, Olaparib with DNA Demethylating agents(5-Azacytidine), in ovarian cancer cell models. Methods: In vitro experiments, we treated Olaparib only, 5-Azacytidine only, and combination with Olaparib and 5-Azacytidine in ovarian cancer cell lines(A2780, SKOV3ip1, HeyA8) to evaluate the effect on cell proliferation using MTT assay. To check the human Active caspase3, MMP2, and MMP9 level and apoptosis according to each treatment, we performed Western blot, ELISA, and apoptosis assay. With wound-healing assay and migration assay, invasive ability of cancer cell after treatment of each inhibitor was compared. For in vivo experiments, cell line xenografts with A2780 and PDX models with implanting tumor(<2-3mm) into subrenal capsule of kidney were used. We recorded tumor weight and number of tumor. Results: Both Olaparib and 5-Azacytidine inhibited the cell survival and increased the apoptosis in ovarian cancer cells. In this study, combination treatment of cells with Olaparib and 5-Azacytidine significantly inhibited the cell growth and increased the apoptosis compared to the single agent treatment in ovarian cancer cells. In in vivo experiments, combination treatment with Olaparib and 5-Azacytidine significantly decreased weight and nodule numbers of tumor in cell-line xenograft models with A2780 cells and PDX model compared with other groups. Conclusion: We found that combination treatment with Olaparib and 5-Azacytidine has synergetic effect to attack ovarian cancer cells compared with control or single agent treatment through in vitro and in vivo tests.
GO-06 : Laparoscopic surgical management of localized recurrent ovarin cancer
( June Kuk Choi ),( E Sun Paik ),( Tae Hyun Kim ),( Aera Yoon ),( Yoo Young Lee ),( Tae Joong Kim ),( Chel Hun Choi ),( Byoung Gie Kim ),( Duk Soo Bae ),( Jeong Won Lee ) 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-
목적: To assess surgical outcomes of laparoscopic secondary or tertiary cytoreduction in carefully selected patients with localized or isolated recurred epithelial ovarian cancer. 방법: This is a retrospective analysis of 13 patients with recurrent ovarian cancer undergoing secondary or tertiary cytoreduction by laparoscopic surgery between July 2009 and December 2013. We analyzed patients characteristics including age, BMI, initial stage, histology and grade, and investigate surgical outcomes such as operative time, recurred mass size, blood loss, length of hospital stay, complications, and disease free survival time. 결과: Of 13 patients recruited for laparoscopic secondary or tertiary cytoreduction with isolated recurred epithelial ovarian cancer, 3 patients had stage I disease, 2 patients had stage II disease and 8 patients had stage III disease at the time of their initial diagnosis. 8 patients (61.5%) underwent secondary laparoscopic cytoreduction, and 5 patients (38.5%) underwent tertiary laparoscopic cytoruduction. Median mass size was 23.9 ± 9.7 mm. The median operating time was 104.9 ± 38.9 min, and the estimated blood loss (EBL) was 135.4 ± 126.6 ml. The median hospital stay was 5.8 ± 3.1 days. One patient had intraoperative complication, who was inserted right ureteral stent due to right ureteral injury during tumor dissection. No postoperative complications occurred. The median progression-free survival was 21 month. 결론: Our study demonstrates that in carefully selected patients with recurrent epithelial ovarian cancer, laparoscopic approach is feasible and safe, and adjuvant treatment may be performed more quickly due to rapid recovery.
강형우(Kang Hyung Woo),윤이중(Yoon E Joong),이수연(Lee Su Yoon),박창섭(Park Chang Seop),이동훈(Lee Dong Hoon) 한국정보처리학회 1999 정보처리학회논문지 Vol.6 No.8
IMT-2000 system is expected to start its service at the beginning of 2000 on the purpose of providing with the highest qualitative service through one mobile terminal. In this paper, we investigate some of the important issues which need to be addressed in designing an authentication protocol for IMT-2000. Also proposed is an authentication protocol which addresses the above issues, and we design a correct and efficient authentication protocol to establish secure communication channel. Our protocol provides an authentication of the communicating entities, location privacy, and secure messaging as well as global roaming service.