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Recent advances in immobilization methods of antibodies on solid supports
Jung, Yongwon,Jeong, Jin Young,Chung, Bong Hyun Royal Society of Chemistry 2008 The Analyst Vol.133 No.6
<P>Antibody immobilization on a solid support is an essential process for the development of most immune-based assay systems. The choice of the immobilization method greatly affects antibody–antigen interactions on the assay surface. For the past several years, numerous strategies have been reported to control antibody immobilization, mainly by directing the orientation, stability, and density of bound antibodies on different assay platforms. Here we discuss recent developments in antibody immobilization methods with a particular focus on the strengths and limitations of reported approaches, and thereby provide a useful guideline for the selection of suitable antibody coupling procedures.</P> <P>Graphic Abstract</P><P>The choice of antibody immobilization method greatly affects antibody–antigen interactions on the assay surface. The process has been optimized, mainly by directing the orientation, stability, and density of bound antibodies. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b800014j'> </P>
Kruppel-like factor 4 attenuates osteoblast formation, function, and cross talk with osteoclasts
Kim, Jung Ha,Kim, Kabsun,Youn, Bang Ung,Lee, Jongwon,Kim, Inyoung,Shin, Hong-In,Akiyama, Haruhiko,Choi, Yongwon,Kim, Nacksung The Rockefeller University Press 2014 The Journal of cell biology Vol.204 No.6
<P>KLF4 controls bone homeostasis by negatively regulating both osteoclast and osteoblast differentiation.</P>
Synthesis of colloidal VO<sub>2</sub> nanoparticles for thermochromic applications
Choi, Yongwon,Sim, Dong Min,Hur, Yoon Hyung,Han, Hyeuk Jin,Jung, Yeon Sik Elsevier 2018 Solar energy materials and solar cells Vol.176 No.-
<P><B>Abstract</B></P> <P>Vanadium dioxide (VO<SUB>2</SUB>) thin films are key materials for thermochromic smart windows and commonly have a typical phase transition (insulator to metal phase) at a transition temperature of 68°C. This research, however, found that highly crystallized VO<SUB>2</SUB> nanoparticles can be successfully coated on a glass substrate with added functionalities, such as higher luminous transmittance and transition efficiency. The transition temperature revealed that the VO<SUB>2</SUB> nanoparticles with post thermal treatment at 600°C also clearly exhibited a reduced transition temperature of 69°C in the heating curve, 59°C in the cooling curve, and a transition width of 10°C. By nanopatterning the thin films, we were able to prepare VO<SUB>2</SUB> thin films with higher luminous transmittance than that attained with non-patterned VO<SUB>2</SUB> thin films. The enhanced transition property was demonstrated using highly crystallized VO<SUB>2</SUB> nanoparticles induced by post thermal treatment, and the luminous transmittance was improved by the nanopatterns on the surface of the VO<SUB>2</SUB> thin films.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Vanadium dioxide nanoparticles are synthesized by thermolysis. </LI> <LI> The crystallinity and microstructure were improved by post thermal annealing. </LI> <LI> Transition temperatures were 69°C and 59°C in the heating and cooling curves. </LI> <LI> Nanopatterned VO<SUB>2</SUB> thin films enhanced the luminous transmittance. </LI> </UL> </P>
치료적 중재 사이 낮잠이 뇌졸중 환자의 운동학습에 미치는 효과
이나정 ( Na Jung Lee ),최용원 ( Yongwon Choi ),최민경 ( Min Kyung Choi ),감경윤 ( Kyung Yoon Kim ) 대한통합의학회 2014 대한통합의학회지 Vol.2 No.3
Purpose : The purpose of this research was to determine the effects of nap between therapeutic interventions on motor learning in patients with stroke. Method : Thirty stroke patients with hemiplegia were participated in this study. After the screening by questionnaire about nap time, the patients were assigned to nap or non-nap group. Therapeutic interventions for 30 min were provided two times per day for 5 days per week and the serial reaction time tasks were conducted 2 times before and after a nap per day for 3 days per week. Between the therapeutic interventions, a nap for 60~120 minutes was allowed to the nap group while non-nap group was not. Intervention programs were carried out during the total 15-day. Result : Compared with the non-nap group, the reaction-precision level of nap group was increased (p<.05) for the non-affected upper extremity in the serial reaction time tasks. Conclusion : This study demonstrated that nap between therapeutic interventions has positive effects on motor learning in patients with stroke.