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Influence of Chinese Cultural Values on Service Quality Dimensions
Miss Ying Ying Liao,Dr. Ebrahim Soltani,Dr. Dan Alex Petrovici 세계문화관광학회 2010 Conference Proceedings Vol.11 No.0
The aim of this study is to explore the influence of Chinese cultural values on service expectations and service determinants from customer perspective. The study utilised an extensive survey-based quantitative methodology and collected 524 questionnaires from two different types of customer across three regions of northern, middle, and southern Taiwan: the five star chain hotel restaurants and the local chain restaurants. The findings are categorised into two structural models. Overall, the findings suggest that academics and practicing managers need to move beyond the Hofstede paradigm if today‘s borderless and wireless cross-cultural management has a chance to be understood and theorized.
Ying-ying Xu,Hai-ru Yu,Jia-yi Sun,Zhao Zhao,Shuang Li,Xin-feng Zhang,Zhi-xuan Liao,Ming-ke Cui,Juan Li,Chan Li,Qiang Zhang 대한암학회 2019 Cancer Research and Treatment Vol.51 No.2
Purpose Although the interferon (IFN) signaling and the paired-like homeodomain transcription factor 2 (PITX2) have both been implicated in the progression of breast cancer (BCa), it remains obscure whether these two pathways act in a coordinated manner. We therefore aimed to elucidate the expression and function of PITX2 during the pathogenesis of endocrine resistance in BCa. Materials and Methods PITX2 expression was assessed in BCa tissues using quantitative reverse transcription polymerase chain reaction (RT-qPCR) and immunohistochemistry and in experimentally induced letrozole-resistant BCa cells using RT-qPCR and immunoblotting. Effects of PITX2 deregulation on BCa progression was determined by assessing MTT, apoptosis and xenograft model. Finally, using multiple assays, the transcriptional regulation of interferon-inducible transmembrane protein 1 (IFITM1) by PITX2 was studied at both molecular and functional levels. Results PITX2 expression was induced in letrozole-resistant BCa tissues and cells, and PITX2 induction by IFN signaling powerfully protected BCa cells against letrozole insult and potentiated letrozole-resistance. Mechanistically, PITX2 enhanced IFN-induced AKT activation by transactivating the transcription of IFITM1, thus rendering BCa cells unresponsive to letrozoleelicited cell death. Additionally, ablation of IFITM1 expression using siRNA substantially abolished IFN-elicited AKT phosphorylation, even in the presence of PITX2 overexpression, thus sensitizing BCa cells to letrozole treatment. Conclusion These results demonstrate that constitutive upregulation of PITX2/IFITM1 cascade is an intrinsic adaptive mechanism during the pathogenesis of letrozole-resistance, and modulation of PITX2/IFITM1 level using different genetic and pharmacological means would thus have a novel therapeutic potential against letrozole resistance in BCa.
SULT1A1 Arg213His Polymorphism and Lung Cancer Risk: a Meta-analysis
Liao, Shao-Guang,Liu, Lu,Zhang, Ying-Yi,Wang, Ying,Wang, Ya-Jie Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.2
Background: The SULT1A1 Arg213His polymorphism is reported to be associated with lung cancer risk. However, this relationship remains controversial. For better understanding a meta-analysis was therefore performed. Methods: An extensive search was performed to identify all case-control studies investigating association between SULT1A1 Arg213His polymorphism and lung cancer risk. The strength was assessed by odds ratio (OR) with the corresponding 95% confidence interval (95%CI). Results: A total of five publications covering 1,669 cases and 1,890 controls were included in this meta-analysis. No significant association between SULT1A1 Arg213His polymorphism and lung cancer risk was observed in overall comparisons in all genetic models (dominant model: OR=1.33, 95%CI=1.00-1.76, P=0.05; additive model: OR=1.30, 95%CI=0.93-1.81, P=0.12; recessive model: OR=1.21, 95%CI=0.89-1.66, P=0.23). However, on subgroup analysis, an elevated risk in mixed populations with variant His allele was revealed in the dominant model (OR=1.66, 95% CI=1.06-2.62, P=0.03). Furthermore, the SULT1A1 Arg213His polymorphism was associated with an increased risk of lung cancer in both females and males in the dominant model (females: OR=1.72, 95%CI=1.29-2.27, P=0.00; males: OR=1.46, 95%CI=1.19-1.78, P=0.00). No significant association between this polymorphism and different smoking status (smokers and non-smokers) and the other ethnicities (Asians and Caucasians) was shown. Conclusions: The results of this meta-analysis indicate that the SULT1A1 Arg213His polymorphism is not associated with lung cancer risk in Asians and Caucasians, but possible elevation for genotype (GA/AA) in mixed populations and males and females needs further investigation.
Liao, Hong-Ying,Wang, Gui-Ping,Gu, Li-Jia,Huang, Shao-Hong,Chen, Xiu-Ling,Li, Yun,Cai, Song-Wang Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.2
Introduction: The esophagus squamous cell carcinoma (ESCC) is one of the most deadly malignances, and a current challenge is the development of effective therapeutic agents. Our present work addressed the effect of HIF-$1{\alpha}$ siRNA alone or in combination with cisplatin on the growth of ESCC in nude mice. Materials and Methods: Xenografts were established by inoculating ESCC TE-1 cells in nude mice, and transplanted tumors were treated with HIF-$1{\alpha}$ siRNA, cisplatin alone or together. Growth was assessed by measuring tumor volume. HIF-$1{\alpha}$ mRNA and protein expression were detected using RT-PCR and immunohistochemistry, respectively. Apoptosis of ESCC TE-1 cells was analyzed by flow cytometry. Results: In our nude mice model, HIF-$1{\alpha}$ siRNA effectively inhibited the growth of transplanted ESCC, downregulating HIF-$1{\alpha}$ mRNA and protein expression, and inducing ESCC TE-1 cell apoptosis. Notably when combinated with cisplatin, HIF-$1{\alpha}$ siRNA showed synergistic interaction in suppressing tumor growth. Furthermore, the proportion of apoptotic cells in HIF-$1{\alpha}$ siRNA plus cisplatin group was significantly higher than that in cisplatin or HIF-$1{\alpha}$ siRNA-treated groups (P<0.05). Conclusions: Down-regulated HIF-$1{\alpha}$ expression induced by siRNA could effectively suppress the growth of transplanted ESCC $in$ $vivo$. HIF-$1{\alpha}$ siRNA could enhance the cytotoxicity of cisplatin, which suggests that a combination of these two agents may have potential for therapy of advanced ESCC.
廖瑩芝(Liao ying zhi) 한국외국어대학교 대만연구센터 2018 대만연구 Vol.- No.12
Thanatos, Drunk by the director Chang Tso Chi is one of the most awarded film in Taiwan of 2015. This film demonstrates the film auteur’s usual focus on the marginalized in Taiwanese contemporary society while applying his signature style of “imaginary ending” to transform the fact of death to a devise revealing the inner aspiration and complex of the protagonists. It is not simply the more defined techniques, nor the LGBT issues the current society eagers to deal with that makes this film stand out among others. Its implication of class issues through family tragedies deepens the characters’ struggles, and the innovative cinematic techniques of blurring the boundaries between realities and the memories visualize the protagonist’s visceral devastation. While death is still the most unbearable for the protagonist, this film further indicates the only path toward redemption is through confronting the cruelest past and the most desperate self. This essay scrutinizes how the family tragedies reflect class issues and the protagonist’s struggles, and further analyzes how the innovative cinematic language visualizes the protagonist’s deepest desperation and leads to his final redemption via the imagined memory of the death.
Integration of Manufacture and Commerce for a Product Learning System in the Service Industry
Shih-Chung Liao,Ying-Ju Angela Pan 한국유통과학회 2014 The Journal of Industrial Distribution & Business( Vol.5 No.2
Purpose - The purpose of this thesis is to assess the product design digital learning status of universities that are currently involved in learning environment projects in manufacture and commerce integration (MCI). Thus, enterprises must keep learning and creating new inventions with revolutionary progress. Research design, data, and methodology - This study not only emphasizes the analysis of technical ability, course concepts, conducting models, and learning environments of every aspect, but also systematically probes the planning of learning, system framework, web learning, environmental activities, data statistics, and digitalized learning, among other aspects. Results - The results of this study help in finally understanding each school’s manufacture and commerce integration situation, in order to evaluate product design learning. Consequently, it is essential to evaluate computer learning at schools, thereby affecting communication and the requirements of business education training. Conclusions - It is essential to focus on MCI to promote web teaching to preserve and enhance knowledge disseminating technologies, and immediately share knowledge with learners, while improving work efficiency and cultivating the talent needed by industry.
Development of a 120 Hz 110 ultra-high-definition a-Si liquid crystal display panel
Yanping Liao,Xibin Shao,Yufan Du,송용지,Weihao Hu,Zhenyu Zhang,Yuqiong Chen,Ying Wang,Qing Ma,윤대근,Dan Wang,Jianfeng Yuan,Hongjiang Wu,Zongjie Guo,Zhaohui Hao,Ji Zhang,Jing Lv 한국정보디스플레이학회 2014 Journal of information display Vol.15 No.2
A prototype 120 Hz 110-inch ultra-high-definition a-Si liquid crystal display (LCD) panel was successfully developed using the BOE exclusive advanced superdimensional switching technology. This LCD has a panel consisting of 3840 × 2160 pixels, four times the number of pixels in the conventional full-high-definition LCD. For the brightness and contrast ratio, 1000 nits and 1200:1 have been achieved, respectively. Additionally, the liquid crystal charging time has been extended through quad area driving and 2G2D line structures. Furthermore, the local dimming and mirror-scanning techniques are applied to realize excellent image display. Finally, the system utilizes 3D shutter glasses, allowing the viewer to achieve the highest sense of realness and immersion.