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      • Semantic Tolerance Relation-based Image Representation and Classification

        Ying Dai 보안공학연구지원센터 2008 International Journal of Software Engineering and Vol.2 No.1

        The nature of the concepts regarding images in many domains are imprecise, and the interpretation of finding similar images is also ambiguous and subjective on the level of human perception. To solve these problems, in this paper, images’ semantic categories and the tolerance degree between them are defined systematically, and the approach of modeling tolerance relations between the semantic classes is proposed. Furthermore, for removing the induced false tolerance in the produce of using semantic tolerance relation model, the method of un-tolerating is introduced in image representation. We apply the proposed approach to the representations of images regarding the nature vs. man-made domain, human vs. nonhuman domain, and temporal domain, and compare the categorization results of them with the results not using semantic tolerance relation model. The results show the effectiveness of proposed method.

      • KCI등재

        Chinese patent herbal medicine (Shufeng Jiedu capsule) for acute upper respiratory tract infections: A systematic review and meta-analysis

        Ying-ying Zhang,Ru-yu Xia,Shi-bing Liang,Xiao-yang Hu,Meng-yuan Dai,Yi-lin Li,Le-yi Zhao,Michael Moore,Yu-tong Fei,Jian-ping Liu 한국한의학연구원 2021 Integrative Medicine Research Vol.10 No.3

        Background: Shufeng Jiedu capsule has been widely used in China for acute upper respiratory tract infections (AURTIs). The aim of this study was to evaluate its effectiveness and safety for AURTIs. Methods: Randomized controlled trials comparing SFJD with conventional drug for patients with AURTIs were included. Eight databases were searched from their inceptions to February 2021. Data was synthesized using risk ration (RR) or mean difference (MD) with their 95% confidence interval (CI). The primary outcome was resolution time of typical symptoms. Results: Twenty-five RCTs involving 3410 patients were included. SFJD in combination with conventional drug was associated with; in common cold shortening the duration of fever (MD −1.54 days, 95% CI [−2.15,−0.92], I2 = 80%, n = 385, 3 trials) and cough (MD −1.22 days, 95% CI [−1.52, −0.93]); in herpangina, shortening the duration of fever (MD -0.68 days, 95% CI [−1.15, −0.21], I2 = 68%, n = 140, 2 trials) and blistering (MD −0.99 days, 95% CI [−1.23, −0.76], n = 386, 3 trials); in acute tonsillitis and acute pharyngitis shortening the duration of fever (MD −1.13 days, 95% CI [−1.36, −0.90], I2 = 33%, n = 688, 7 trials) and sore throat (MD −1.13 days, 95% CI [−1.40, −0.86], I2 = 84.1%, n = 1194, 10 trials). SFJD also improving their cure rate with a range (1–5 days). No serious adverse events were reported. Conclusion: Low certainty evidence suggests that SFJD appears to shorten the duration of symptoms in AURTIs, improve cure rate and seems safe for application. However, high quality placebo controlled trials are warranted to confirm its benefit.

      • KCI등재
      • KCI등재

        Autophagy plays a protective role against apoptosis induced by toxicarioside N via the Akt/mTOR pathway in human gastric cancer SGC-7901 cells

        Huan-ge Zhao,Song-lin Zhou,Ying-ying Lin,Hua Wang,Hao Fu Dai,Feng-Ying Huang 대한약학회 2018 Archives of Pharmacal Research Vol.41 No.10

        Toxicarioside N (Tox N), a natural product extract from Antiaris toxicaria, has been reported to induce apoptosis in human gastric cancer cells. However, the mechanism and actual role of autophagy in Tox N-induced apoptosis of human gastric cancer cells remains poorly understood. In the current study, we demonstrated that Tox N could induce autophagy by inhibiting the Akt/mTOR signaling pathway in SGC-7901 cells. Moreover, we found that the inhibition of autophagy by 3-methyladenine, an autophagy inhibitor, enhanced Tox N-induced apoptotic cell death. However, the stimulation of autophagy by rapamycin, an autophagy activator, remarkably suppressed Tox N-induced apoptosis, suggesting that autophagy plays a protective role in Tox N-induced apoptosis. Thus, the results from this study suggested that Tox N combination with an autophagy inhibitor might be a promising strategy to enhance the anticancer activity of Tox N for the treatment of human gastric cancer.

      • KCI등재

        Toxicarioside N induces apoptosis in human gastric cancer SGC- 7901 cell by activating the p38MAPK pathway

        Huan-ge Zhao,Song-lin Zhou,Ying-ying Lin,Hao Fu Dai,Feng-Ying Huang 대한약학회 2018 Archives of Pharmacal Research Vol.41 No.1

        Natural plant compounds with potent proliferationinhibition and apoptosis induction properties havebeen screened as novel anticancer drugs. Toxicarioside N(Tox N) was isolated from the seeds of the tropical plantAntiaris toxicaria in Hainan province, China. To ourknowledge, the effects that Tox N has on the apoptosis ofSGC-7901 cells and its potential mechanism have neverbeen investigated. In this study, we detected the anticanceractivities of Tox N and explored the potential mechanismin the human gastrointestinal cancer cell line SGC-7901. Here, we found that Tox N inhibited SGC-7901 cell growthin a dose- and time-dependent manner and induced apoptosisin cells based on cell morphology and flow cytometryanalyses. Additionally, the SGC-7901 cell treated with ToxN up-regulated the expression level of cleaved caspase-3/9and PARP, increased the Bax/Bcl-2 ratio, and led to therelease of cytochrome c into the cytoplasm. In addition,Tox N treatment led to the phosphorylation of p38MAPK. SB203580, a p38MAPK inhibitor, partially attenuated ToxN induced apoptosis by preventing the activation of caspase-3/9 and PARP. Our results indicated for the first timethat Tox N can induce SGC-7901 cells apoptosis by activatingthe p38MAPK pathway.

      • Discussing On RFID Tag Conflict Problem

        Dai Yin-fei,Li Nian-feng,Zong Ying-yong 보안공학연구지원센터 2015 International Journal of Multimedia and Ubiquitous Vol.10 No.3

        This paper introduces the basic concept, development process, key technology of RFID and related theory. And in view of the key technology of RFID, anti collision algorithm is analyzed. Tag collision algorithm is to solve the reading and writing implement effective communications within the scope of multiple tags at the same time, speaking, reading and writing for communication problems. Under the condition of keep a certain complexity and cost, minimize the search time, improve the efficiency of recognition, is the direction and trend of algorithms. Through the comparison of several kinds of algorithm for collision, clear the necessity of the collision algorithm is improved. The author select dynamic frame ALOHA algorithm, introduces in detail the improved algorithm, and apply it to the system, to improve the recognition efficiency.

      • KCI등재

        A kind of core cross-linked ‘‘semi-amphiphilic” polymer assemblies for controlled release of corrosion inhibitors and autonomous corrosion alarm

        Ying Cao,Aoqi Zhu,Jianmin He,Jianhua Wu,Mingjin Xue,Yiting Xu,Birong Zeng,Guorong Chen,Lizong Dai 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.115 No.-

        A novel kind of core cross-linked assemblies formed from a ‘‘semi-amphiphilic” block copolymer, poly(syringaldehyde methacrylate)-block-poly (dopamine methacrylate-co-methyl methacrylate-costyrene)(PSMA-b-P(DMA-co-MMA-co-St)), was designed and served as the carrier for anti-corrosiveand corrosion detective molecules. Different from the core cross-linked micelles formed by the amphiphilicpolymers in water, the core cross-linked assemblies in this research were formed from the ‘‘semiamphiphilic”block copolymer, which took advantage of the different compatibility between epoxy andthe blocks in the polymer, leading to the self-assembly behavior happening in the organic resin, whilethey shared the advantages of traditional core cross-linked micelles with the properties of being stable,stimuli-responsive and multifunctional. The pH-responsive properties of the assemblies and their complexationwith Fe3+ caused by the corrosion of the steel were confirmed by UV spectrophotometry andXPS analysis of the corrosive products. The controlled release of corrosion inhibitors was fully reflectedby the expansion of the capacitor ring and the increase of the coating resistance (Rc) with the extensionof the immersion time, which was got via fitting the electrochemical impedance spectroscopy (EIS) datawith the equivalent electric circuits. Ultimately, the anti-corrosive mechanism of smart coating with thefunctional core cross-linked assemblies were also illustrated.

      • KCI등재

        The Role of Intestinal Microbiota and Mast Cell in a Rat Model of Visceral Hypersensitivity

        ( Ying-jie Li ),( Jing Li ),( Cong Dai ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2020 Journal of Neurogastroenterology and Motility (JNM Vol.26 No.4

        Background/Aims To explore the role of intestinal flora and mast cells in visceral hypersensitivity (VH). Methods The experimental animals were divided into 4 groups: control group, VH group, VH + VSL#3 group, and VH + ketotifen group. Stool samples were collected from each group (n = 3) for a further analysis using 16S ribosomal DNA gene sequence. Visceral sensitivity was evaluated by abdominal withdrawal reflex (AWR) score. Colon tissues of rats were obtained from each group. Mast cells were detected by toluidine blue staining. The degranulation of mast cells was assessed by transmission electron microscopy. Results VH rat model could successfully be induced by acetic acid enema combined with partial limb restraint method. Compared with rats in the control group, AWR score, number of mast cells, and degranulation of mast cells were increased in the VH rats, which could be reduced by administration of ketotifen or probiotic VSL#3. Clostridium sensu stricto 1 abundance was higher in the VH group compared to the control group, which could be restored by application of probiotic VSL#3. Conclusions Probiotic VSL#3 decreases visceral sensitivity in VH rats. The mechanism may be related to mast cell and intestinal flora. Change of Clostridium sensu stricto 1 abundance may be a basis for VH observed in irritable bowel syndrome and may be prevented by specific probiotic administration. (J Neurogastroenterol Motil 2020;26:529-538)

      • KCI등재

        NVST Data Archiving System Based On FastBit NoSQL Database

        Ying Bo Liu,Feng Wang,Kai-fan Ji,Hui Deng,Wei Dai,Bo Liang 한국천문학회 2014 Journal of The Korean Astronomical Society Vol.47 No.3

        The New Vacuum Solar Telescope (NVST) is a 1-meter vacuum solar telescope that aims to observe the fine structures of active regions on the Sun. The main tasks of the NVST are high resolution imaging and spectral observations, including the measurements of the solar magnetic field. The NVST has been collecting more than 20 million FITS files since it began routine observations in 2012 and produces a maximum observational records of 120 thousand files in a day. Given the large amount of files, the effective archiving and retrieval of files becomes a critical and urgent problem. In this study, we implement a new data archiving system for the NVST based on the Fastbit Not Only Structured Query Language (NoSQL) database. Comparing to the relational database (i.e., MySQL; My Structured Query Language), the Fastbit database manifests distinctive advantages on indexing and querying performance. In a large scale database of 40 million records, the multi-field combined query response time of Fastbit database is about 15 times faster and fully meets the requirements of the NVST. Our study brings a new idea for massive astronomical data archiving and would contribute to the design of data management systems for other astronomical telescopes.

      • KCI등재

        Profile of disposition, tissue distribution and excretion of the novel anti-human immunodeficiency virus (HIV) agent W-1 in rats

        Ying-Yuan Lu,Xiao-Wei Wang,Xin Wang,Wen-Bing Dai,Qiang Zhang,Pu Li,Ya-Qing Lou,Chuang Lu,Jun-Yi Liu,Guo-Liang Zhang 대한약학회 2016 Archives of Pharmacal Research Vol.39 No.7

        The purpose of this study was to characterize the disposition, distribution, excretion and plasma protein binding of 6-benzyl-1-benzyloxymethyl-5-iodouracil (W- 1) in rats. Concentrations of W-1 within biological samples were determined using a validated high performance liquid chromatography method. The plasma protein binding of W-1 was examined by equilibrium dialysis method. After oral administration of W-1 (50, 100 and 200 mg/kg, respectively) in self-microemulsifying drug delivery system formulation, the pharmacokinetic parameters of W-1 were as follows: the peak plasma concentrations (Cmax) were 0.42, 1.50 and 2.55 μg/mL, the area under the curve (AUC0-t) were 0.89, 2.27 and 3.96 lg/h mL and the plasma half-life (t1/2) were 5.15, 3.77 and 3.77 h, respectively. Moreover, the prototype of W-1 was rapidly and extensively distributed into fifteen tissues, especially higher concentrations were detected in intestine, stomach and liver, respectively. The plasma protein binding of W-1 in rat, beagle dog and human were in the range of 97.96–99.13 %. This study suggested that W-1 has an appropriate pharmacokinetics in rats, such as rapid absorption, moderate clearance, and rapid distribution to multiple tissues. Those properties provide important information for further development W-1 as an anti-HIV-1 drug candidate.

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