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      • Automatic Fish Species Identification using Convolutional Neural Networks

        ( Yi-chin Lu ),( Ching-lu Hsieh ),( Yan-fu Kuo ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

        Fish is a worldwide major food source. In recent years, overfishing has become a serious problem. Overfishing exhausts fish resources, endangers some fish species, and also threatens the entire marine food chain. Hence, organizations put regulations to prevent overfishing. Typically, the species of the fish caught are recorded and reported by ocean observers. However, the manual reporting method is laborious and time-consuming. This study proposed to recognize fish species from images automatically using deep convolutional neural networks (CNN). A first deep CNN was used to identify fish types (e.g., tuna, marlin, shark, and other). A second deep CNN was used to distinguish species of tuna fish, including Thunnus alalunga (Albacore), Thunnus obesus (Bigeye tuna), Thunnus albacares (Yellowfin tuna). A third deep CNN was used to determine the species of marlin fish, including Makaira nigricans (Atlantic blue marlin), Istiophorus platypterus (Indo-Pacific sailfish), Xiphias gladius (Swordfish). Each deep CNN was a fine-tuned VGG-16 model. The experimental results showed that the proposed method reached an average accuracy of 97.9%.

      • KCI등재

        Eccentric strength and design of RC columns strengthened with SCC filled steel tubes

        Yi-Yan Lu,Hong-Jun Liang,Shan Li,Na Li 국제구조공학회 2015 Steel and Composite Structures, An International J Vol.18 No.4

        Self-compacting Concrete Filled steel Tubes (SCFT), which combines the advantages of steel and concrete materials, can be applied to strengthen the RC columns. In order to investigate the eccentric loading behavior of the strengthened columns, this paper presents an experimental and numerical investigation on them. The experimental results showed that the use of SCFT is interesting since the ductility and the bearing capacity of the RC columns are greatly improved. And the performance of strengthened columns is significantly affected by four parameters: column section type (circular and square), wall thickness of the steel tube, designed strength grade of strengthening concrete and initial eccentricity. In the numerical program, a generic fiber element model which takes in account the effect of confinement is developed to predict the behavior of the strengthened columns subjected to eccentric loading. After the fiber element analysis was verified against experimental results, a simple design formula based on the model is proposed to calculate the ultimate eccentric strength. Calibration of the calculated results against the test results shows that the design formula closely estimates the ultimate capacities of the eccentrically compressed strengthened columns by 5%.

      • RTN4 3'-UTR Insertion/Deletion Polymorphism and Susceptibility to Non-Small Cell Lung Cancer in Chinese Han Population

        Lu, De-Yi,Mao, Xu-Hua,Zhou, Ying-Hui,Yan, Xiao-Long,Wang, Wei-Ping,Zheng, Ya-Biao,Xiao, Juan-Juan,Zhang, Ping,Wang, Jian-Guo,Ashwani, Neetika,Ding, Wei-Liang,Jiang, Hua,Shang, Yan,Wang, Ming-Hua Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.13

        Nogo protein, encoded by gene reticulon-4 (RTN4), includes three major isoforms by different splicing, named Nogo-A Nogo-B and Nogo-C. Nogo proteins play an important role in the apoptosis of cells, especially in tumor cells. RTN4 single nucleotide polymorphisms (SNPs) can influence the efficiency of transcription and translation thus being related with an individual's predisposition to cancer. The CAA insertion/deletion polymorphism (rs34917480) within RTN4 3'-UTR has been reported to be associated with many cancer types. In order to investigate the relationship between this polymorphism and susceptibility to non-small cell lung cancer (NSCLC) in the Chinese population, we conducted the present case-control study including 411 NSCLC patients and 471 unrelated healthy controls. The genotype distributions were significantly different between cases and controls (p=0.014). We found that the del allele could significantly increase NSCLC risk (ins/ins vs ins/del: p=0.007, OR 1.46, 95%CI=1.11-1.93; dominant model: p=0.004, OR 1.47, 95%CI=1.13-1.92 and allele model: p=0.008, OR 1.35, 95%CI=1.08-1.67). This association was stronger in participants over 60 years old, males and smokers. We therefore conclude that the CAA insertion/deletion polymorphism (rs34917480) contributes to non-small cell lung cancer risk in Chinese population. Age, sex and environmental exposure are also related to carcinogenic effects of rs34917480.

      • KCI등재

        Effect of the Outer Diameter on the Behavior of Square RC Columns Strengthened with Self-Compacting Concrete Filled Circular Steel Tube

        Yi-Yan Lu,Zhenzhen Liu,Shan Li,Xiaobo Zhao 한국강구조학회 2019 International Journal of Steel Structures Vol.19 No.3

        This paper aimed to investigate the optimum outer diameter of square RC columns strengthened with self-compacting concrete fi lled circular steel tube. An experiment of twelve strengthened RC columns (SRC) and two referential RC columns subjected to axial load was presented. The variables considered in the test were the confi nement index and the diameter of the strengthened section. The experimental results showed that, with the same confi nement index, the material strength utilization of SRC columns dropped with the increasing of strengthened section diameter. There existed an optimum outer diameter to take full use of material strength. With the outer diameter below the optimum value, the material strength utilization increased with increasing confi nement index. As the outer diameter beyond the optimum one, the material strength utilization decreased with improving confi nement index.

      • KCI등재

        Axial behavior of RC columns strengthened with SCC filled square steel tubes

        Yi-Yan Lu,Hong-Jun Liang,Shan Li,Na Li 국제구조공학회 2015 Steel and Composite Structures, An International J Vol.18 No.3

        Self-compacting Concrete (SCC) Filled Square steel Tubes (SCFST) was used to strengthen square RC columns. To establish the efficiency of this strengthening method, 17 columns were tested under axial compression loading including 3 RC columns without any strengthening (WRC), 1 RC column strengthened with concrete jacket (CRC), 13 RC columns strengthened with self-compacting concrete filled square steel tubes (SRC). The experimental results showed that the use of SCFST is interesting since the ductility and the bearing capacity of the RC columns are greatly improved. The improvement ratio is significantly affected by the nominal wall thickness of steel tubes (<i>t</i>), the strength grade of strengthening concrete (C), and the length-to-width ratio (L /B) of the specimens. In order to quantitatively analyze the effect of these test parameters on axial loading behavior of the SRC columns, three performance indices, enhancement ratio (ER), ductility index (DI), and confinement ratio (CR), were used. The strength of the SRC columns obtained from the experiments was then employed to verify the proposed mode referring to the relevant codes. It was found that codes DBJ13-51 could relatively predict the strength of the SRC columns accurately, and codes AIJ and BS5400 were relatively conservative.

      • KCI등재

        Slender RC columns strengthened with combined CFRP and steel jacket under axial load

        Yi-Yan Lu,Shan Li,Na Li,Tian-yan Ou 국제구조공학회 2015 Steel and Composite Structures, An International J Vol.19 No.5

        This paper presents an experimental study on the effectiveness of simultaneous application of carbon fiber-reinforced polymer (CFRP) and steel jacket in strengthening slender reinforced concrete (RC) column. The columns were 200 mm square cross section with lengths ranging from 1600 to 3000 mm. Ten columns were tested under axial load. The effects of the strengthening technique, slenderness ratio, cross-section area of steel angle and CFRP layer number were examined in terms of axial load-axial strain curve, CFRP strain, steel strip strain and steel angle strain. The experiments indicate that strengthening RC columns with combined CFRP and steel jacket is effective in enhancing the load capacity, ductility and energy dissipation capacity of RC column. Based on the existing models for RC columns strengthened with CFRP and with steel jacket, a design formula considering a slenderness reduction factor is proposed to predict the load capacity of the RC columns strengthened with combined CFRP and steel jacket. The predictions agree well with the experimental results.

      • Clinical Study on Safety and Efficacy of Qinin<sup>®</sup> (Cantharidin Sodium) Injection Combined with Chemotherapy in Treating Patients with Gastric Cancer

        Zhan, Yi-Ping,Huang, Xin-En,Cao, Jie,Lu, Yan-Yan,Wu, Xue-Yan,Liu, Jin,Xu, Xia,Xu, Lin,Xiang, Jin,Ye, Li-Hong Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9

        Objectives: To assess the efficacy, side effects, and the impact on quality of life with $Qinin^{(R)}$ (Cantharidin sodium) injection combined with chemotherapy for gastric cancer patients. Method: A consecutive cohort of 70 patients were divided into two groups: experimental group with cantharidin sodium injection combined with chemotherapy, while the control group received chemotherapy alone. After more than two courses of treatment, efficacy, quality of life and side effects were evaluated. Results: The response rate of experimental group was not significantly different from that of the control group (P>0.05), but differences were significant in clinical benefit response and KPS score. In addition, gastrointestinal reactions and the incidence of leukopenia were lower than in the control group (P<0.05). Conclusions: $Qinin^{(R)}$ (Cantharidin sodium) injection combined with chemotherapy enhances clinical benefit response, improving quality of life of gastric cancer patients and reducing side effects of chemotherapy. Thus $Qinin^{(R)}$ (Cantharidin sodium) injection deserves to be further investigated in randomized control clinical trails.

      • Clinical Safety and Efficacy of Kanglaite<sup>®</sup> (Coix Seed Oil) Injection Combined with Chemotherapy in Treating Patients with Gastric Cancer

        Zhan, Yi-Ping,Huang, Xin-En,Cao, Jie,Lu, Yan-Yan,Wu, Xue-Yan,Liu, Jin,Xu, Xia,Xiang, Jin,Ye, Li-Hong Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10

        Objective: To observe efficacy and side effects, as well as the impact on quality of life, of Kanglaite$^{(R)}$ (Coix Seed Oil) injections combined with chemotherapy in the treatment of advanced gastric cancer patients. Method: A consecutive cohort of 60 patients were divided into two groups: the experimental group receiving Kanglaite$^{(R)}$ Injection combined with chemotherapy and the control group with chemotherapy alone. After more than two courses of treatment, efficacy, quality of life and side effects were evaluated. Results: The response rate and KPS score of experimental group were significantly improved as compared with those of the control group (P<0.05). In addition, gastrointestinal reactions and bone marrow suppression were significantly lower than in the control group (P<0.05). Conclusions: Kanglaite$^{(R)}$ Injection enhanced efficacy and reduced the side effects of chemotherapy, improving quality of life of gastric cancer patients; use of Kanglaite$^{(R)}$ injections deserves to be further investigated in randomized control clinical trails.

      • KCI등재

        Improvement of Fumigaclavine C Production in a Two-stage Culture of Aspergillus fumigatus with Molasses as a Cost-effective Ingredient

        Yi-Xiang Zhu,WEIWEI HUAN,Ling-yun Yao,Wan-Guo Yu,Ruihua Jiao,Yan-Hua Lu,Renxiang Tan 한국생물공학회 2015 Biotechnology and Bioprocess Engineering Vol.20 No.6

        Fumigaclavine C (FC), which is produced by Aspergillus fumigatus, is a conidiation-associated ergot alkaloid with significant medical benefits. However, its application is restricted by low yields from submerged cultures. In this study, the technical feasibility of using molasses as a cost-effective ingredient for FC production in a two-stage culture of A. fumigatus was evaluated. The results indicated that molasses supplementation significantly enhanced FC accumulation by promoting conidiation and up-regulating hydroxymethylglutaryl-CoA reductase activity. Via the optimization of the two-stage process in the presence of molasses, FC production in shake flasks reached 226.9 mg/L, which was approximately three times that in the original medium (75.9 mg/L). The use of molasses as a cost-effective ingredient for FC fermentation was also successfully reproduced in a lab-scale bioreactor system in which the maximum FC production reached 215.0 mg/L. The FC production obtained in this study is the highest ever reported. This increased efficiency will enable large-scale production of FC and extend the application of molasses as a low-cost substrate for producing other conidiation-related secondary metabolites.

      • KCI등재

        Improved Control Strategy Based on Space Vectors for Suppressing Grid-Side Current Harmonics in Three-Phase Current Source Rectifiers with a Hybrid Switch

        Yan Xu,Guang-xiang Lu,Li-jie Jiang,Gui-Ping Yi 전력전자학회 2015 JOURNAL OF POWER ELECTRONICS Vol.15 No.2

        This paper analyses the harmonic pollution to power grids caused by several high-power rectifiers, summarizes the requirements for rectifiers in suppressing grid-side current harmonics and optimizes a new-type of current source PWM rectifier with a hybrid switch. The rectifier with a hybrid switch boasts significant current characteristics and cost advantages in the high-power area. To further enhance the working frequency of the current source rectifier with a hybrid switch for suppressing grid-side harmonics and reducing the inductance size, this paper proposes an optimal control strategy based on space vector. It also verifies that the optimal control strategy based on space vector can reduce the total harmonic distortion of the grid-side current of the rectifier with a hybrid switch via circuit simulation and experimental results.

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