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      • KCI등재

        HAPS와 NGSO 시스템의 Service Link상의 간섭영향

        양의장,김규환,함형일,강영흥 한국항행학회 2003 韓國航行學會論文誌 Vol.7 No.1

        본 논문에서는 성층권 통신 시스템 (HAPS : High Altitude Platform System)과 NGSO (Non-Geostationary Orbit) 시스템간 간섭 영향을 두 가지의 경우로 나누어서 분석한다. 한가지는 HAPS 시스템이NGSO 시스템에 미치는 간섭이며, 다른 한가지는 NGSO위성이 HAPS시스템에 미치는 간섭 영향이다. 그 결과NGSO 이동국이 받는 간섭은 NGSO위성 위치가 95?일 때 가장 높게 나타났으며, 이때 HAPS와 NGSO모두에 의한 간섭은 사용자 수가 20명 이상부터 간섭 기준을 초과함을 알 수 있었다. 그리고 HAPS 이동국이 받는 간섭의 경우에는 NGSO 위성 양각이 87?일 때 가장 높은 간섭이 나타났으며, 이 때 NGSO와 HAPS 모두에 의한 간섭은 사용자 수가 10명 이상부터 간섭 기준을 초과함을 알 수 있었다. 또한 64?일 때 가장 낮은 간섭이 나타났으며, 이때 NGSO와 HAPS 의 사용자 수가 같을 경우에는 190명에서부터 간섭을 초과함을 알 수 있었다. In this paper, we analyze the interference effects between NGSO(Non-Geostationary Orbit) and HAPS(High Altitude Platform System) by dividing into two cases. The one is interference effects of HAPS into NGSO, the another is the interference effectes of NGSO into HAPS. At the result, we can know the interference effect into NGSO mobile station is the highest when position of NGSO is 95%. In this case, we can also know the interference effects from both HAPS and NGSO exceed interference criteria when the number of users are more than 20. And, in the case of the interference effect into HAPS mobile station, we can know it is the highest when elevation angle of NGSO is 87°, and the interference effects from both NGSO and HAPS exceed interference criteria when the number of users is more then 10. Moreover, the interference effect is the minimum, when elevation angle of NGSO is 64°, at this time, in case that the number of users of NGSO equal to the number of user of HAPS, the interference effects exceed interference criteria when the number of users is 190.

      • KCI등재

        데페록사민 전처치가 토끼 심근경색 크기의 감소에 미치는 효과

        양관모,오동렬,박승현,박규남,이원재,김형국,황두영,최승필,채장성 대한응급의학회 1998 대한응급의학회지 Vol.9 No.4

        Background: Reperfusion of ischemic myocardium has been postulated to result in a specific oxygen radical mediated tissue injury. Iron may liberate during ischemia and we hypothesized that administration of the iron chelator, deferoxamine during ischemia would result in improved recovery after postischemic reperfusion. Purpose: To test whether iron-catalyzed processes contribute to myocardial necrosis during ischemia and reperfusion, deferoxamine was administered to block iron catalyzed hydroxyl radical formation in rabbits. Methods: Eleven rabbits were divided into two groups : control group (n=5) and deferoxamine pretreatment group (n=6). The left circumflex coronay artery was ligated for 30 minutes and reperfused for 180 minutes. Area at risk (AR) was measured by non-stained area with methylene blue injection into left atrium after left circumflex coronary artery ligation. Infarct size was measured by weighing after triphenyltetrazolium chloride staining. Heart rate was measured using electrocardiographic recording and systemic blood pressure was monitored by pressure transducer connected to the catheter in the left ventricle. Results: 1. There was no significant difference of heart rate and blood pressure in deferoxamine pretreatment group compared with control group. 2. There was significant decrease of serum iron concentration after continuous infusion of deferoxamine compared with serum iron concentration before ligation of coronary artery(P<0.05). 3. There was no significant difference of area at risk between control and deferoxamine pretreatment group. 4. Area at necrosis to area at risk was significantly reduced in deferoxamine pretreatment group compared with control group(P<0.05). The results suggest that deferoxamine infusion prior to coronary artery occlusion has a significant benefit in reducing infarct size in this model.

      • KCI등재

        치태 형성과 휘발성 유황화합물 생성을 억제하는 Lactobacillus salivarius의 분리 및 동정

        김미형,양규호,최남기,김선미,오종석 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.2

        우리 인체에는 의학적으로 유용한 기능을 가진 세금들이 정상적으로 존재하며 구강내에도 독특한 기능을 나타내는 세균들이 상재한다. 본 연구에서는 치아우식증이 없는 소아의 타액에서 분리한 유산균 2주가 Streptococcus mutans에 의한 인공치태 형성과 혐기성 세균에 의한 휘발성 유황화합물 생성을 억제하는 것을 화인하고, API 50 CHL medium kit를 이용한 생화학적 검사와 165 rDNA sequencing으로 동정하여 다음과 같은 결과를 얻었다 1. 분리균주는 2주 모두 그람양성 간균으로 과산화수소를 생성하였다. 2. 인공치태의 무게는 Streptococcus 단독 배양시 124.4土30.4mg이었으나, 분리균주와 병합 배양시에는 각각 5.2±2.0mg, 10.6±6.6mg으로 현저하게 감소하였다(p<0.05). 3. Steptococcus mutans의 생균수는 단독 배양시 ml단 3.4×10^(9)이었으나, 분리균주와 병합 배양시에는 각각 ml당 4.6x1과 2.4×10^(8)으로 감소하였다. 4. Fusobacterium nucleatum을 30분간 진탕한 후 측정한 상청액의 흡광도는 1.286이었으나, Fusobacterium nucleatum과 분리균주를 병합으로 30분간 진탕한 후 측정한 상청액의 흡광 도는 각각 0.628과 0.497로 감소하였으며, 상호결합 정도는 29.4%와 57.8%이었다 5. Fusobacterium nucleatum 단독 배양시 cysteine과 FeSO₄를 첨가한 배지를 가한 후 측정한 침전물의 배지 흡광도는 1.794이었으나, 분리균주와 병합 배양시 측정한 침전물의 배지 흡광도는 각각 1.144와 0.915로 감소하였으며, Porphyromonas gingivalis단독 배양시 침전물의 배지 흡광도는 1.932이었으나 분리균주와 병합 배양시에는 침전물의 배지 흡광도가 각각 1 170과 1.266으로 감소하였다. 6. 분리균주를 API 50 CHL medium kit로 탄수화물 발효검사를 시행한 결과, 분리균주 1주는 Lactobacillus salivarius로, 다른 분리균주는 Lactobacillus delbruekii subsp. salicinius로 동정되었다. 7. 분리균주를 165 rDNA partial sequencing으로 동정 한 결과, 2주 모두 Lactobacillus salivarius subsp. sailcinius와 유전자 유사치가 99.60% 99.73%를 보여 Lactobacillus salivarius subsp. salicinius로 동정되었다. 이상의 결과를 종합하면 치아우식증이 없는 소아의 타액에서 분리된 유산균 중 과산화수소를 분비하여 인공치태 형성과 휘발성 유황화합물 생성을 억제하는 분리균주는 Lactobacillus salivarius subsp. Salicinius로 동정되었다. There are normal inhabitants doing medically useful functions in the body. There are many kinds of bacteria performing specific functions in the oral cavity. Two strains of lactic acid bacteria were isolated from inhabitants of caries-free children's oral cavity, which inhibited the formation of artificial plaque by Streptococcus mutans and the production of volatile sulfur compounds by anaerobic bacteria. The isolates were identified by the test using API 50 CHL medium kit and 16S rDNA partial sequencing. 1. Two isolates were Gram-positive bacilli and produced hydrogen peroxide. 2. When Streptococcus mutans was cultured in the media, the mean weight of formed artificial plaque on the orthodontic wires was 124.4±30.4 mg. whereas being reduced to 5.2±2.0mg and 10.6±6.6mg in the media cultured with Streptococcus mutans and each isolate, respectively (pW.05). 3. The number of viable cells of Streptococcus mutans was 3.4 x 10^(9) per ml in the cultured solution, whereas those of Streptococcus mutans in the combined culture with each of isolates were 4.6x 10^(8) and 2.4x 10^(8) per ml. 4. The optical density was 1.286 in the supernatant of Fusobacteriumn nucleatum after vortexing fol 30minutes, whereas in the supernatant of combined Fusobacterium nucleatum and each isolate, they were reduced to 0.628 and 0.497, which the percentages of coaggregation between them were 29.4% and 57.8%, respectively. 5. The optical density of Fusobacterium nucleatum precipitate was 1.794 in the culture media containing cysteine and FeSO4, being reduced to 1.144 and 0.915 in the coaggregated precipitates of Fusobacterium nucleatum and each isolate. The optical density of Porphyromonas gingivalis precipitate was 1,932 in the culture media, being reduced to 1.170 and 1.266 in the coaggregated precipitates of Porphyromonas gingivalis and each isolate, 6. When two isolates were tested with API 50 CHL medium kit, those were identified as Lactobaciallius salivarius and Lactobacillus delbrueckii subsp. lactis. 7. The similarity values of 16S rDNA sequence between each of isolates and Lactobacillus salivarius subsp. salicinius were 99.60% and 99.73%, respectively, meaning that isolates were Lactobacillus salivarius sub-sp. salicinius. These results indicated that two strains isolated from caries-free children's saliva, which inhibited the formation of artificial plaque and the production of volatile sulfur compounds, were identified as Lactobacillus salivarius subsp. salicinius.

      • KCI등재

        복합 치아종에 관한 증례보고

        최형준,최병재,손흥규,양호정 大韓小兒齒科學會 1995 大韓小兒齒科學會誌 Vol.22 No.2

        The odontoma is relatively a common odontogenic tumor. It has come to mean as a growth in which both the epithelial and the mesenchymal cell exhibit complete differentiation, with the result that functional ameloblast and odontoblast form enamel and dentin. The etiology of it is unknown, but it has been suggested that local trauma or infection may lead to the production of such a lesion. Odontma is divided into 2 types. One is compound odontoma that is at least superficial anatomic simiarity to normal teeth, and the other is complex odontoma, that calcified dental tissues are simply an irregular mass bearing no morphologic similarity even to rudimentary teeth. Somtimes this malformation is not easily identified because its lacking of calcification. So, if permanant tooth is delayed to erupt, one should take a careful look the radiographic film to find that whether the cause of it is odontoma or not. In this case report, 3 patients with odontoma who visited Dept. of Pediatric Dentistry in Yonsei Dental College, were treated by means of surgical removal. The obtained results were as follows: 1. The odontoma is usually related to impacted tooth, and it is occurred neighboring to the crown of impacted tooth that have normally developed. So, in the case of missing tooth and delayed eruption, its presence should be investigated. 2. The odontoma can be seen vaguely radiographically, so, it is difficulty to make diagnosis. 3. The treatment of odontoma is a surgical removal. And, if it is completely removed, its occurrence is rare. 4. In the case of impacted tooth being associated with compound odontoma, continuous management is necessary for the eruption of impacted tooth after the surgical extraction of odontoma. 5. It resembles the ameloblastic odontoma radigraphically, and if it is the case, the treatment may vary, so the confirmation through histologic examination after removal of mass is necessary.

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