http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Shaking Table Test on Seismic Responses of a Monolithic Precast Concrete Shear Wall Structure
Chao-gang Qin,Guoliang Bai,Ya-zhou Xu,Ning Fen Su,Tao Wu,Zhong Liang Li,Yu Zhe Sun 대한토목학회 2018 KSCE Journal of Civil Engineering Vol.22 No.10
To examine the seismic performance of Monolithic Precast Concrete Shear Wall (MPCSW) structure, a 1/5-scaled twelve-story model is designed and investigated by shaking table test, and connections between the precast elements and their impact on seismic performance of the overall model are comprehensively inspected and analyzed. Based on the testing results, the structural responses are divided into elastic stage and plastic stage, and the variations of dynamic characteristics, cracking and failure pattern, seismic responses of the model are accordingly presented. The experimental results indicate that most of critical cracks of the MPCSW model locate on the coupling beams and horizontal connections of precast concrete shear walls, and the fundamental frequency exhibits a successively decreasing trend during the entire testing process. Furthermore, The MPCSW model is designed in accordance with Chinese codes meets the requirement for the seismic fortification intensity of eight, and shows an adequate safety margin to resist collapse in the case of 0.90 g.
Two new tirucallane triterpenoids from the leaves of Aquilaria sinensis
Jin Tang Cheng,Ya Qiong Han,Juan He,Xing De Wu,Liao Bin Dong,Li Yan Peng,Yan Li,Qin Shi Zhao 대한약학회 2013 Archives of Pharmacal Research Vol.36 No.9
Two new tirucallane triterpenoids, aquilacallanesA–B (1–2), together with 15 known compounds(3–17) were isolated from the leaves of Aquilaria sinensis. The structures of these new compounds were elucidated onthe basis of extensive spectroscopic analyses. All compoundswere evaluated for their cytotoxic activity againstfive human cancer cell lines. The known compounds,ursolic acid (7) and 5,7,40-trimethoxyflavone (14), exhibitedweak cytotoxic activity against some cells.
Wang Shen,Lin Li-mei,Wu Yong-ning,Fang Min,Yu Ya-qin,Zhou Jia,Gong Zhi-yong 한국식품과학회 2014 Food Science and Biotechnology Vol.23 No.5
In vitro and in vivo antihypertensive effects ofgrass carp peptides (GCP) were investigated. The aminoacid composition and the angiotensinconverting enzymeinhibitory activity were evaluated using HPLC. GCP wasadministrated to spontaneously hypertensive rats (SHRs)and Wistar Kyoto rats (WKY) by single and long-termadministration before blood pressure measurements. Plasma levels of angiotensin II (Ang II), rennin (RA), nitricoxide (NO), and plasma angiotensin I converting enzyme(ACE) activity were measured. The GCP molecular weightwas between 725 and 1,228 Da with high levels of Leu,Asp, Phe, Gly, and Pro. The in vitro IC50 value was 0.23mg/mL. GCP lowered SHR blood pressure dose and timedependently. Little change occurred in WKY. The plasmalevel of Ang II and the ACE activity decreased. SHR RAand NO concentrations in plasma increased. Theantihypertensive effect of GCP was associated with NOregulation and the rennin-angiotensin system.
Chen, Hai-Fei,Li, Zheng-Yang,Tang, Jie-Qing,Shen, Hong-Shi,Cui, Qing-Ya,Ren, Yong-Ya,Qin, Long-Mei,Jin, Ling-Juan,Zhu, Jing-Jing,Wang, Jing,Ding, Jie,Wang, Ke-Yuan,Yu, Zi-Qiang,Wang, Zhao-Yue,Wu, Tian Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9
Objective: To investigate the relationship between the efficacy and safety of different doses of thalidomide (Thal) plus dexamethasone (Dex) as the initial therapy in elderly patients with newly diagnosed multiple myeloma (MM). Methods: Clinical data of 28 elderly patients with newly diagnosed MM who underwent the TD regimen as the initial therapy were analyzed retrospectively. The patients were divided into two groups according to the maximal sustained dose of Thal: lower dose (group A) and higher dose (group B). The overall response rate (ORR), progression free survival (PFS), overall survival (OS), and adverse events (AES) were compared between the two groups. Results: A total of 28 patients were followed up with a median of 18 months. The ORR was 60.1%. The median response time and PFS were 2.0 and 17.0 months, respectively. The mean sustained dose of Thal in group B was significantly higher than group A (292.9 mg v 180.4 mg, P=0.01). There was no significantly difference in ORR (57.1% v 64.3%, P=1.00) and PFS (9.63months v 17.66 months, P=0.73) between groups A and B. During the follow up, only five patients died (<40%) and, therefore, median OS values were not available. It is estimated, however, that the mean survival time in the two groups was 35.6 and 33.4 months (P>0.05), respectively. All of the patients tolerated the treatment well. The incidence of AES in patients with a grading above 3 in group B was significantly higher than in group A (P=0.033). Conclusions: The TD regimen results in a high response rate and manageable AES as the initial therapy in elderly patients with MM. TD should be considered as the front line regimen for the treatment of elderly patients with MM in areas with financial constraints. The clinical response can be achieved at a low dose Thal with minimal toxicity.