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      • Comparison of cortical bone thickness and root proximity at maxillary and mandibular interradicular sites for orthodontic mini-implant placement

        Lim, JE,Lee, SJ,Kim, YJ,Lim, WH,Chun, YS Blackwell Publishing Ltd 2009 Orthodontics & craniofacial research Vol.12 No.4

        <P>Structured Abstract</P><P>Authors – </P><P>Lim JE, Lee SJ, Kim YJ, Lim WH, Chun YS</P><P>Objectives – </P><P>To compare maxillary and mandibular cortical bone thickness and rootic proximity for optimal mini-implant placement.</P><P>Setting and Sample Population – </P><P>CT images from 14 men and 14 women were used to evaluate buccal interradicular cortical bone thickness and root proximity from mesial of the central incisor to the 2nd molar. Cortical bone thickness was measured at 0°, 15°, 30°, and 45° angles relative to the root surface using three-dimensional images.</P><P>Results – </P><P>For the cortical bone thickness, there was no statistically significant difference between the maxilla and the mandible in the anterior area; however, there was a significant difference in the posterior area. Cortical bone in the maxilla, mesial and distal to canine interradicular sites, was thickest while thickness in the mandible exhibited a gradual anterior to posterior increase. Cortical bone thickness in the maxilla increased as both level and angle increased, while the cortical bone thickness in the mandible was greatest at 4 mm from the alveolar crest. Root proximity mesial and distal to 2nd premolar interradicular sites was greatest.</P><P>Conclusion – </P><P>Based on our results, cortical bone thickness depends on the interradicular site rather than sex or individual differences.</P>

      • KCI등재

        급성 양수과다증을 동반한 이분 척추 무뇌 기형아 1예

        이영순(YS Lee),홍자선(JS Hong),정영숙(YS Chung),박동흥(DH Park) 대한산부인과학회 1968 Obstetrics & Gynecology Science Vol.11 No.5

        A case of anencephalus with spina bifida associated with severe acute hydramnios is presented and it`s literature is reviewed briefly.

      • KCI등재

        경관임신

        김영수(YS Kim),김재욱(JU Kim),최영실(YS Chey) 대한산부인과학회 1972 Obstetrics & Gynecology Science Vol.15 No.5

        병리조직학적으로 확진된 자궁경임신 5례를 치험하였기에 문헌적인 고찰과 아울러 보고하는 바이다. 본증의 경우 5례가 모두 인공임신중절수술을 받은 기왕력을 가지고 있으므로 경관임신의 성인과 관련있을 것으로 사료된다. 임신초기에 수술시 혹은 그 전후에 의심스러운 출혈이 있을시 본증을 고려해 봄이 의의가 있다고 본다. Five cases of pregnancy during a year, 1971 are presented with a brief review of literatures and have been analysed for gravity, abortion, parity, treatment, duration of gestation, and proved completely to be cervical pregnancy. Previous history of artificial termination of pregnancy may be one of the etiological factors since all the cases presented have had artificial termination at least two or more. Itis important to consider cervical pregnancy whenever there is any uneventful bleeding in early pregnancy and or during and after curettage.

      • KCI등재

        자궁내막간질육종의 1례

        박영세(YS Park),김동진(DJ Kim),신순철(SC Shin),장윤석(YS Chang) 대한산부인과학회 1978 Obstetrics & Gynecology Science Vol.21 No.1

        A case of endometrial stromal sarcoma was described with its clinical and pathological findings. A brief review on the literatures was made in comment.

      • KCI등재

        성숙 및 미성숙 인간난자의 체외수정 및 난할율에 관한 연구

        장윤석(YS Chang),이진용(JY Lee),문신용(SY Moon),김정구(JK Kim),손영수(YS Son),이상훈(SH Lee),김정훈(JH Kim),오선경(SK Oh) 대한산부인과학회 1986 Obstetrics & Gynecology Science Vol.29 No.10

        난관의 원인으로 불임증이 확인된 정사월경주기를 가진 71명의 환자를 대상으로 25명을 human menopausal gonadotropin으로, 46명은 follicle stimulating hormone/human menopausal gonadotropin로 과배란을 유도하였다 과배란유도 후 각군별로 혈중 estradiol치와 난포직경을 측정하고, 복강경으로 난자를 흡인한 후 난자의 성숙도를 판정하고, 체외수정 시켜서 난할율 및 임신율을 조사하여 다음과 같은 결론을 얻었다 1 혈중 E2의 농도는 hCG주사 당일 hMG를 사용한 제일군(n=25)은 986 7±503 9pg/ml, FSH/hMG를 사용한 제이군(n=46)은 1,208 7±663 4pg/ml로 유의하게 제일군이 제이군보다 낮은 수치를 보여 주었다 2 hCG주사당일 최대 난포의 직경은 제일군은 14 8±2 7㎜이었고, 제이군은 16 0±2 2㎜이었으며, 양군간에는 유의한 차이점을 발견할 수 없었다 3 hCG주사당일 난포의 직경이 10㎜이상에 도달한 난포수는 제일군이 4 8(120/25)개, 제이군이 5 0(232/46)개 이었다 양군사이에서 난포의 크기별 분포 및 난포수에 있어서 유의한 차이를 관찰할 수 없었다 4 환자당 흡인된 난포 수는 제일군은 5 6(128/23)개, 제이군 5 9(265/45)개 이었고, 나자수는 제일군은 3 5(80/23)개, 제이군은 4 0(181/45)개이었다 양군 사이에서 흡인된 난포수 및 난자수에 있어서 유의한 차이를 관찰할 수 없었다 5 난포액 흡인후 관찰한 나자중 성숙된 난자의 성숙된 난자의 획득율은 제일군은 80개의 난자중 62개로 77 5%, 제이군은 181개의 난자중 156개로 86 2%이었다 미성숙 난자의 획득율은 제일군은 17개로 21 2%, 제이군은 20개로 11 0%이었다 6 수정후 44시간후의 성숙된 난자의 난할율은 제일군은 43개의 나자중 27개가 난할되어 62 8%, 제이군은 120개의 난자중 72개가 난할되어 60%의 난할율을 확인하여 평균 60 7%(99/163)의 난할율을 나타내었다 7 수정후 60시간 후의 성숙된 난자의 난할율은 제일군은 19개의 관찰한 난자중 13개가 난할이 관찰되어 68 4%, 제이군은 36개의 난자중 21개에서 난할되어 58 3%의 난할율을 확인하였으며 평균 61 8%(34/55)의 난할율을 확인하였다 8 흡인된 미성숙 난자를 체외에서 24시간 이상 성숙시킨다음 수정후 40시간 후의 난할율은 제일군에서는 8개의 미성숙 난자중 3개가 난할되어 37 5%, 제이군은 13개의 미성숙 난자중 6개가 난할되어 46 2% 난할율을 획득 하였으며 평균 42 9%의 난할율을 확인하였다 9 제일군에서 Seventy one patients were stimulated by hMG (n=25) and FSH/hMG (n=46) for the purpose of in vitro fertilization and embryo transfer To compare the clevage rate of preovulatory oocytes and immature oocytes, maturity of aspirated oocytes were determined by virtue of morphologic characteristics of oocyte-cumulus-complex Pre-ovulatory oocytes were routinely incubated for 6 hours prior to insemination, while immature oocyte were inseminated for 16 hours in a Ham`s F-10 based insemination medium with 7 5% fetal cord serum After insemination both oocytes were transferred to growth medium with 15% fetal cord serum Of the aspirated oocytes, 218 (83 5%) were considered preovulatory, 37 (0 14%) were immature, 2 (0 8%) were postmature and 4 (1 5%) were degenerative Clevage rate of preovulatory oocytes were 60 7% (99/163) at 44 hours and 61 8% (34/55) at 60 hours post insemination period There were no significant difference of clevage rate between 44 hours period and 60 hours period in case of preovulatory oocytes 42 9% (9/21) clevage rate of immature oocytes were confirmed of 40 hours post insemination period There were significant difference of clevage rate of pre-ovulatory oocytes and immature oocytes There pregnancies were established from 50 transferred patients But no pregnancy were resulted from the transfer of only developed immature oocytes It was concluded that IVF program immature oocytes would be recovered along with the pre-ovulatory oocytes and successful in vitro maturation of these oocytes ensures a wider range of fertilizable oocytes and should therefore increase the opportunity for securing a pregnancy

      • KCI등재

        선천성 질결여증의 1례

        박영상(YS Park),목영소(YS Mok),길운향(WH Ghil),최금숙(KS Choi),박진배(JB Park) 대한산부인과학회 1982 Obstetrics & Gynecology Science Vol.25 No.3

        We present a case of congenital absence of the vagina associated with a variable abnormality of kidney and lumbar spine, with a review of literature. Our experience, particulaly with the Simple vulvovaginoplasty technique, is given. Postoperative support and encouragement are needed to have a successful outcome.

      • Role of NAD(P)H oxidase in the tamoxifen-induced generation of reactive oxygen species and apoptosis in HepG2 human hepatoblastoma cells

        Lee, YS,Kang, YS,Lee, SH,Kim, JA 영남대학교 약품개발연구소 2001 영남대학교 약품개발연구소 연구업적집 Vol.11 No.-

        Previously, tamoxiten (TAM) has been shown to induce apoptosis through elevation of intracellular Ca^(2+) in HepG2 human hepatoblastoma cells. In this study we investigated the role of reactive oxygen species (ROS) in the TAM-induced apoptosis, and interrelationship between intracellular Ca^(2+) and ROS. TAM induced a slow and sustained increase in intracellular ROS level. An antioxidant, N-acetlycysteine signlficantly inhibited both ROS production and apoptosis induced by TAM, suggesting that ROS may play an essential role in the TAM-lnduced apoptosis. In a time frame ROS generation followed lntracellular Ca^(2+) increase, and the extracellular and intracellular Ca^(2+) chelation with EGTA and BAPTA/AM, respectively, completely inhibited the TAM-induced ROS production, lndicating that intracellular Ca^(2+) may mediate the ROS generation. Inhibitors of NAD(P)H oxidase, diphenylene iodonium, phenylarsine oxide and neopterine, signlficantly blocked the TAM-induced ROS generation and apoptosis, implying that this oxidase may act as a source enzyme for the production of ROS. These results suggest that non-phagocytic NAD(P)H oxidase may paly a novelroleas a mediator of the apoptosis associated with intracellular Ca^(2+) in HepG2 cells. Cell Death and Differentiation (2000)7,925-932.

      • KCI등재

        다발성 원발성 부인암 8 예

        김진,신연승,남상륜,서영석,박선국,박윤석 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.7

        저자들은 지난 10 년간 충남대학교 산부인과에서 치료한 총 993 예의 여성 생식기 암 중 동시성 다발성 원발성 부인암 8 예를 경험하였기에 간단한 문헌 고찰과 함께 보고하는 바이다. Multiple primary cancer means that more than 2 cancers are independently deveoped in one individual. The incidence of multiple primary cancer is increasing gradually due to accurate cancer registry, earlier diagnosis and treatment and increased exposure to carcinogen. We report 8 cases of multiple primary gynecologic cancer involving cervix, ovary, endometrium and vulva. Three cases are synchronous multiple primary cancer of cervix. Two cases are synchronous multiple primary cancer of endometrium and ovary. One case is synchronous multiple primary cancer of ovary and vulva. One case is metachronous multiple primary cancer of cervix and vulva. One case is synchronous multiple primary cancer of cervix and ovary.

      • KCI등재

        복막에 발생한 미만성 악성 중피종 1 예

        김진,신연승,남상륜,서광선,서영석,박윤석 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.8

        저자 등은 발생 예가 드문, 복막에 발생한 미만성 악성 중피세포종 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Primary malignant mesothelioma of the peritoneum is a rare condition(annual incidence: 1∼2 cases per million in the general population). A case of diffuse malignant mesothelioma of the peritoneum of a 54-year-old woman is reported. After laparotomy the patient was treated with intraperitoneal chemotherapy with cisplatin (100 mg), postoperative chemotherapy (6 cycles) with carboplatine (350 mg/m2), and cyclophosphamide (750 mg/m2). In the second-look operation, malignant mesothelioma was as minute nodules at the site of adhesion. So she had further treated with combination chemotherapy using cyclophamide (500 mg/m2) and pinorubicin (40mg/m2), and continude follow up of the CA 125 levels. The patient it still alive and the serum CA 125 level showed a close relation with the reponse to treatment (Surgery and chemotherapy). On the basis of the data from literature, we briefly review the epidemiology, diagnosis, and treatment of malignant peritoneal mesothelioma.

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