Bowen 씨 병의 1 예

고재경 대한피부과학회 1964 대한피부과학회지 Vol.3 No.1

WDNM1 is associated with differentiation and apoptosis of mammary epithelial cells.

Kho, Yoonjung,Kim, Sungchan,Yoon, Byung Sun,Moon, Jai-Hee,Kwak, Sungwook,Park, Gyuman,Woo, Junghee,Oh, Sejong,Hong, Kichang,Kim, Saehun,Kim, Hyunggee,You, Seungkwon,Choi, Yunjaie Marcel Dekker 2008 Animal biotechnology Vol.19 No.2

<P>In this study, we show that expression of the Westmead DMBA8 nonmetastatic cDNA 1 (WDNM1) gene was increased upon SFM and/or TNFalpha treatment, with a corresponding increase in apoptotic cells, and gradually decreased following re-stimulation with serum in HC11 mammary epithelial cells. TNFalpha induced WDNM1 expression showed the NFkappaB-dependent mechanism since it's expression was abrogated in IkappaBalphaM (super-repressor of NFkappaB)-transfected cells, but not those transfected with control vector. Furthermore, overexpression of WDNM1 suppressed growth and differentiation, and accelerated apoptosis of HC11 cells. Thus, our results demonstrate that WDNM1 gene expression, regulated by the TNFalpha-NFkappaB signal pathway, is associated with HC11 cell apoptosis.</P>

A Contrastive Analysis between English and Korean Vowel Phonemes for Teaching English

Kho, Byung Am 한국현대영어영문학회 1982 현대영어영문학 Vol.22 No.1

Path intersection matrices and applications to networks

Kho, D.Y.,Kook, W.,Lee, J.,Lee, J.,Lee, K.J. North Holland [etc.] 2017 Linear algebra and its applications Vol.524 No.-

<P>For a network G, we introduce a non-singular symmetric matrix, called a path intersection matrix, that will provide a new method for computing the ratio k(G)/k(G/ab) where k(G) is the tree-number of G and G lab is obtained from GUab by contracting the new edge ab between two distinct nodes a and b. The quantities k(G)/k(G/ab) appear as invariants for various networks such as effective conductance for an electrical network and an ingredient for information centrality for a social network. We will review several examples of networks where path intersection matrices can be applied. (C) 2017 Elsevier Inc. All rights reserved.</P>

KITENIN recruits Dishevelled/PKC δ to form a functional complex and controls the migration and invasiveness of colorectal cancer cells

Kho, D.H.,Bae, J.A.,Lee, J.H.,Cho, H.J.,Cho, S.H.,Lee, J.H.,Seo, Y.-W.,Ahn, K.Y.,Chung, I.J.,Kim, K.K. BMJ PUBLISHING GROUP 2009 Gut Vol.58 No.4

A report of three unrecorded Ovulid species (Gastropoda, Heterodonta) from Korea

Kho, Dong-Bum,Lee, Jun-Sang,Min, Duk-Ki The Malacological Society of Korea 2015 The Korean Journal of Malacology Vol.31 No.1

Three Ovulid species collected from Jeju Island were identified as Habuprionovolva aenigma (Azuma & Cate, 1971), Habuprionovolva basilia (Cate, 1978) and Diminovula kosugei (Cate, 1973). This is the first record from the Korean waters, providing a description of the species with illustration for the shell morphology.

Genetic and environmental influences on sodium intake determined by using half-day urine samples: the Healthy Twin Study

Kho, Minjung,Lee, Jung Eun,Song, Yun-Mi,Lee, Kayoung,Kim, Kyunga,Yang, Sarah,Joung, Hyojee,Sung, Joohon American Society for Clinical Nutrition 2013 The American journal of clinical nutrition Vol.98 No.6

<P><B>Background:</B> Salt is essential in our diet, but excess intake is a well-established risk factor for hypertension. The presence and importance of genetic contributions to salt intake, however, are not well understood.</P><P><B>Objective:</B> The aim of this study was to examine whether a genetic predisposition and an environmental influence exist for sodium intake and salt habit.</P><P><B>Design:</B> In a twin-family cohort, half-day urine samples from 1204 individuals (133 pairs of monozygotic twins, 29 pairs of dizygotic twins, and 880 singletons) were collected to assess 24-h sodium intakes. Daily total sodium intake, sodium density per calorie (Na-D), and salt habit questions were analyzed with adjustment for other epidemiologic characteristics. We calculated heritability (h2) and intraclass correlations to examine the genetic and shared environmental contributions to total sodium intake traits.</P><P><B>Results:</B> The average sodium intake was 208.4 ± 107.0 mmol/d. Men had a higher absolute sodium intake (242.6 ± 117.4 mmol/d), but Na-D did not differ by sex. Moderate genetic influences existed (h2 = 0.31–0.34) for sodium intake and Na-D. We also found that sharing current residence rather than being a family member explained 22% of the variance in Na-D.</P><P><B>Conclusion:</B> Our findings suggest that both genetic predisposition and shared environment contribute to sodium intakes and salt habits alike.</P>

Cancelable fingerprint template design with randomized non-negative least squares

Kho, Jun Beom,Kim, Jaihie,Kim, Ig-Jae,Teoh, Andrew B.J. Elsevier 2019 Pattern recognition Vol.91 No.-

<P><B>Abstract</B></P> <P>Although biometrics is considered more competent than password-based or token-based approach in identity management, biometric templates are vulnerable to adversary attacks that may lead to irreversible identity loss. One of the promising remedies for biometric template protection is cancelable biometrics. In this paper, a novel binary cancelable fingerprint template design based on Partial Local Structure (PLS) descriptor and Permutated Randomized Non-Negative Least Square (PR-NNLS) is proposed. The PLS descriptor is an alignment-free minutia descriptor, which is conceived to be coupled with the PR-NNLS to derive a binary protected fingerprint template that satisfies non-invertibility, unlinkability, cancelability and performance criteria. The PR-NNLS formulation is unique in such a way that the noninvertible transformation is applied to the PLS descriptor dictionary instead of applying it to the minutiae descriptor, which often invites performance deterioration. The evaluations have been carried out with five subsets from FVC 2002 and 2004 databases where the proposed method is attested to fulfill the aforementioned four template protection criteria. We also analyze four privacy and security attacks targeted to cancelable biometrics.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A novel alignment-free minutiae descriptor that based on Partial Local Structure (PLS) is proposed, which is beneficial to generate discriminative and compact binary cancelable fingerprint template. </LI> <LI> The non-invertible transformation of the PLS descriptor is formulated as a problem of solving randomized Non-Negative Least Square (R-NNLS) optimization problem, which is unique in a way to get rid of the performance deterioration issue when applying the non-invertible transformation directly to the minutiae descriptor for the fingerprint template protection. </LI> <LI> The revocability and the unlinkability traits of the proposed method are enabled by introducing a permutation mechanism to the R-NNLS. </LI> <LI> The proposed method is rigorously evaluated with five benchmark datasets, and four security and privacy analyses are also carried out. </LI> </UL> </P>

Administration of placenta-derived mesenchymal stem cells counteracts a delayed anergic state following a transient induction of endogenous neurogenesis activity after global cerebral ischemia

Kho, A Ra,Kim, Ok Joon,Jeong, Jeong Hyun,Yu, Ji Min,Kim, Hye Sun,Choi, Bo Young,Suh, Sang Won,Chung, Tae Nyoung Elsevier 2018 Brain Research Vol.1689 No.-

<P><B>Abstract</B></P> <P><B>Background</B></P> <P>Global cerebral ischemia (GCI) is a major obstacle for cardiac arrest survival. Recent studies have suggested the possibility of mesenchymal stem cell (MSC) as a novel therapeutic option for GCI, but these results were limited to the neuroprotective effects of MSCs. Therefore, we aimed to investigate specific characteristics of neurogenesis after transient GCI, and to assess the effect of MSC on these characteristics.</P> <P><B>Methods</B></P> <P>Adult male Sprague–Dawley rats were subjected to 7 min of transient GCI and randomized into 7 groups: baseline, MSC, and control administered groups, to be analyzed at 2, 3, and 4 weeks after GCI, respectively. The same interventions were repeated for sham operated animals. Rats were euthanized at the designated time after GCI.</P> <P><B>Results</B></P> <P>A comparison of GCI and sham groups without MSC treatment, showed that the counts of bromodeoxyuridine (BrdU)- and doublecortin (DCX)-positive cells were significantly increased in the GCI group at 1 week after insult, but the trend was reversed at 3 weeks after insult. The counts of BrdU-, Ki67- and DCX-positive cells and the intensity of zinc translocator 3 (ZnT3) were all significantly higher in the MSC-treated group than those in the control group at 3 weeks after GCI. The count of NeuN-positive cells in the hippocampus was significantly increased in the MSC group at 4 weeks after GCI.</P> <P><B>Conclusions</B></P> <P>GCI induces transient neurogenesis, followed by an anergic state. MSC may counteract this anergy of neurogenesis and result in an increase in intact neurons in later stages.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Neurogenesis increased after global cerebral ischemia but decreased soon. </LI> <LI> MSC administration counteracted the decrease of neurogenesis activity. </LI> <LI> Counteraction of MSC to anergy of neurogenesis resulted in more intact neurons. </LI> <LI> Effect of MSC on neurogenesis activity is consistent with ZnT3 expression. </LI> </UL> </P>

Agora and Its Possibilities in James Joyce’s “Wandering Rocks”

Kho, Younghee 미래영어영문학회 2021 영어영문학 Vol.26 No.1

Reviving and representing the concept of agora, a central space for the politics, economy, and religion of ancient Greek city-states, this paper claims that Joyce in Dubliners and Ulysses evaluates the limitations and possibilities of Ireland as an emerging nation through the citizens’ interactions in agora. Focusing on this public space’s role for communication, the paper pays attention to the kinds and characters of communication especially in “Eveline” and “Wandering Rocks.” In the former story, Eveline is occupied in her uncommunicable concern of whether or not she has to leave Ireland, yet her agoraphobia ultimately ends her communication with others, especially with Frank who she regards as a possible savior from her stifling situation. The citizens in “Wandering Rocks” do not show such physical symptoms of agoraphobia as Eveline; however, their consciousness and communication still expose what obstructs themselves from intellectual development. The pretentious and uncharitable attitude of Dubliners, perhaps except for foreign Bloom and female Molly, marks their communication everywhere and develops a false community in this episode. Molly and Bloom, in contrast, open up possibilities for building an ideal community through the act of charity, which is particularly emphasized in this episode.