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Placement of Parameter Server in Wide Area Network Topology for Geo-Distributed Machine Learning
li, yongyao,Fan, Chenyu,Zhang, Xiaoning,Chen, Yufeng 한국통신학회 2023 Journal of communications and networks Vol.25 No.3
Machine learning (ML) is extensively used in a widerange of real-world applications that require data all aroundworld to pursue high accuracy of a global model. Unfortunately,it is impossible to transmit all gathered raw data to a centraldata center for training due to data privacy, data sovereigntyand high communication cost. This brings the idea of geo-distributed machine learning (Geo-DML), which completes thetraining of the global ML model across multiple data centerswith the bottleneck of high communication cost over the limitedwide area networks (WAN) bandwidth. In this paper, we studyon the problem of parameter server (PS) placement in PSarchitecture for communication efficiency of Geo-DML. Ouroptimization aims to select an appropriate data center as thePS for global training algorithm based on the communicationcost. We prove the PS placement problem is NP-hard. Further,we develop an approximation algorithm to solve the problemusing the randomized rounding method. In order to validate theperformance of our proposed algorithm, we conduct large-scalesimulations, and the simulation results on two typical carriernetwork topologies show that our proposed algorithm can reducethe communication cost up to 61.78% over B4 topology and21.78% over Internet2 network topology.
Advanced On-chip SOL Calibration Method for Unknown Fixture De-embedding
Changwook Yoon,Bichen Chen,Xiaoning Ye,Jun Fan 대한전자공학회 2017 Journal of semiconductor technology and science Vol.17 No.4
SOL (Short, Open and Load) calibration based on iterative error sensitivity is proposed in this paper. With advanced SOL calibration, unknown parasitic parameters at on-chip terminations are accurately estimated up to 20 GHz. Artificial terminations are designed on printed circuit board (PCB) to experiment the proposed method. On-chip SHORT, OPEN and LOAD fabricated inside silicon shows the accuracy of proposed calibration method through the comparison with known fixture Sparameter after de-embedding.
Advanced On-chip SOL Calibration Method for Unknown Fixture De-embedding
Yoon, Changwook,Chen, Bichen,Ye, Xiaoning,Fan, Jun The Institute of Electronics and Information Engin 2017 Journal of semiconductor technology and science Vol.17 No.4
SOL (Short, Open and Load) calibration based on iterative error sensitivity is proposed in this paper. With advanced SOL calibration, unknown parasitic parameters at on-chip terminations are accurately estimated up to 20 GHz. Artificial terminations are designed on printed circuit board (PCB) to experiment the proposed method. On-chip SHORT, OPEN and LOAD fabricated inside silicon shows the accuracy of proposed calibration method through the comparison with known fixture S-parameter after de-embedding.
Preparation and Antioxidant Activities of High Fischer’s Ratio Oligopeptides from Goat Whey
Yusi Qin,Ming Cheng,Xiaoxue Fan,Xiaoqing Shao,Cunfang Wang,Hua Jiang,Xiaoning Zhang 한국축산식품학회 2022 한국축산식품학회지 Vol.42 No.5
This study aimed to obtain high Fischer’s ratio oligopeptides from goat whey (HFO) and investigate antioxidant property of it. Hydrolysis of goat whey was done with the approach of sequential digestion of pepsin and flavourzyme. With the adsorption of aromatic amino acids by activated carbon, HFO with a Fischer’s ratio of 27.070 and a molecular weight of 200–1,000 Da were obtained, and the branched-chain amino acids accounted for 22.87%. Then the antioxidant activity of HFO was evaluated. At the concentrations of 2.0 mg/mL and 0.50 mg/mL, HFO scavenged 77.27% and 99.63% of 1,1- diphenyl-2-picrylhydrazyl and 3-ethylbenzthiazoline-6-sulphonate free radicals respectively. The scavenging rate of HFO against hydroxyl radicals reached 92.31% at the concentration of 0.25 mg/mL. Animal experiments demonstrated that HFO could moderate the changes of malondialdehyde, superoxide dismutase and glutathione peroxidase caused by CCl4- induced oxidative stress in vivo. This study indicated that HFO from goat whey was capable of oxidation resistance both in vivo and in vitro, which provided a scientific basis for the high-value processing and application of goat milk whey.
Expression profiling identified IL-8 as a regulator of homotypic cell-in-cell formation
( Banzhan Ruan ),( Chenxi Wang ),( Ang Chen ),( Jianqing Liang ),( Zubiao Niu ),( You Zheng ),( Jie Fan ),( Lihua Gao ),( Hongyan Huang ),( Xiaoning Wang ),( Qiang Sun ) 생화학분자생물학회(구 한국생화학분자생물학회) 2018 BMB Reports Vol.51 No.8
Homotypic cell-in-cell (CIC) structures forming between cancer cells were proposed to promote tumor evolution via entosis, a nonapoptotic cell death process. However, the mechanisms underlying their formation remained poorly understood. We performed a microarray analysis to identify genes associated with homotypic CIC formation. Cancer cells differing in their ability to form homotypic CIC structures were selected for the study. Association analysis identified 73 probe sets for 62 candidate genes potentially involved in CIC formation. Among them, twenty-one genes were downregulated while 41 genes were upregulated. Pathway analysis identified a gene interaction network centered on IL-8, which was upregulated in high CIC cells. Remarkably, CIC formation was significantly inhibited by IL-8 knockdown and enhanced upon recombinant IL-8 treatment, which correlated with altered cell-cell adhesion and expression of adhesive molecules such as P-cadherin and γ-catenin. Together, our work identified IL-8 as a positive regulator of homotypic CIC formation via enhancing intercellular adhesion. [BMB Reports 2018; 51(8): 412-417]