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Taewook Kang,Bangho Gwon 대한공간정보학회 2016 Spatial Information Research Vol.24 No.6
This study aims to analyze the productivity of automatic 3D reverse engineering for architectural mechanical, electrical and plumbing (MEP) pipe objects modeling. Recently, 3D image scan-based reverse engineering is emerging technology in facility management, operation domain. However, because a large amount of scanned point cloud data is so complex and difficult, it requires manual task additionally. Manual-based reverse engineering occurs low-productivity, data loss and error. We suggest the process of automatic 3D reverse engineering work for modeling pipeline which occupies the largest part of MEP phase. Furthermore, this study analyzes the productivity effect related to the proposed method. The results show that the productivity is improved from 118 to 162% (average work effectiveness: 141%).
Kang Taewook,Park Si Young,Lee Soon Hyuck,Park Jong Hoon,Suh Seung Woo 대한의학회 2022 Journal of Korean medical science Vol.37 No.13
Background: Denosumab (DEN) and zoledronic acid (ZOL) currently represent the most potent antiresorptive agents for the treatment of osteoporosis. Despite similar effects on bone resorption, these agents have distinct mechanisms of action. The objective of this study was to compare the effect of DEN and ZOL after two-year administration on bone mineral density (BMD), trabecular bone score (TBS), bone turnover markers, and persistence. Methods: A total of 585 postmenopausal women with osteoporosis who did not use osteoporosis medications were retrospectively reviewed. 290 patients were administered 60 mg DEN subcutaneously every 6 months from 2017 to 2018, and 295 patients were treated with 5 mg ZOL intravenously yearly from 2015 to 2017. BMD, TBS, and C-terminal crosslinking telopeptide of type 1 collagen (CTX) measurements were obtained at baseline and two-year after DEN injection or ZOL infusion. Results: After two-year follow-up, 188 patients in the DEN group and 183 patients in the ZOL group were compared. BMD change from baseline at two years was significantly greater in the DEN group compared with the ZOL group (P < 0.001). The changes of TBS in the DEN group were statistically significant compared with baseline (P < 0.001) and the ZOL group (P < 0.001). The DEN group led to significantly greater reduction of CTX compared with ZOL group (P = 0.041). Conclusion: In postmenopausal women with osteoporosis, DEN was associated with greater BMD increase at all measured skeletal sites, greater increase of TBS, and greater inhibition of bone remodeling compared with ZOL.
An Energy Combiner for a Multi-Input Energy-Harvesting System
Taewook Kang,Sungeun Kim,Changhee Hyoung,Sungweon Kang,Kyunghwan Park IEEE 2015 IEEE Transactions on Circuits and Systems II: Expr Vol. No.
<P>An energy combiner for delivering electrical energy harvested simultaneously from individual energy harvesters (EHs) to a single energy storage device such as a battery is presented. It is designed as a modular architecture to be handled as a subsystem and supports an arbitrary number of EHs, which can be connected to the energy combiner in a hot-pluggable form. With the adaptive connection flows of a novel control algorithm, the energy harvested from each EH can be transmitted to an energy storage device without interfering with each other. An evaluation system is implemented, including the energy combiner circuit fabricated in a 0.13-μm CMOS process. The experimental results show that the energy combiner, with a low power consumption of 1.55 μW, achieves a maximum energy-combining efficiency of up to 95% for three input sources.</P>
Kang, Taewook,Oh, Seogil,Hong, Surin,Moon, Jungwoo,Yi, Jongheop Royal Society of Chemistry 2006 Chemical communications Vol.2006 No.28
<P>A new simpler concept about the signal amplification of surface plasmon resonance (SPR) that is based on the utilization of mesoporous silica thin films is demonstrated. As compared to monolayer based coatings, mesoporous silica thin films of ∼200 nm extend the interaction arena away from the metal, thus permitting the integration of the change in optical contrast at different distances from the sensor surface.</P> <P>Graphic Abstract</P><P>A new simpler concept about the signal amplification of surface plasmon resonance (SPR) that is based on the utilization of mesoporous silica thin films is demonstrated. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b600140h'> </P>
Kang, Taewook,Hong, Surin,Moon, Jungwoo,Oh, Seogil,Yi, Jongheop Royal Society of Chemistry 2005 Chemical communications Vol.2005 No.29
<P>The proposed procedure for recycling the sensor surface consists of (1) the self-assembly of 2-aminoethanethiol hydrochloride (AET) on the Au substrate, (2) the neutralization of zwitterion-like species, –NH<SUB>3</SUB><SUP>+</SUP>Cl<SUP>−</SUP> to –NH<SUB>2</SUB> by treatment with a NaOH solution (pH 11), (3) the detection of Cu<SUP>2+</SUP> on the NaOH-treated AET–Au substrate, and finally (4) regeneration of the sensor surface from [–NH<SUB>2</SUB> → Cu<SUP>2+</SUP>] to [–NH<SUB>3</SUB><SUP>+</SUP>Cl<SUP>−</SUP>] by treatment with 1 M HCl.</P> <P>Graphic Abstract</P><P>The proposed procedure for recycling the sensor surface consists of (1) the self-assembly of 2-aminoethanethiol hydrochloride, (2) the neutralization of zwitterion-like species, –NH<SUB>3</SUB><SUP>+</SUP>Cl<SUP>−</SUP> to –NH<SUB>2</SUB>, (3) the detection of Cu<SUP>2+</SUP>, and finally (4) regeneration of the sensor surface. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b504064g'> </P>
Kang, Taewook,Kim, Jae Ho,Hong, Ingie,Park, Nam Hyun,Park, Nanhyun,Heinsen, Helmut,Lee, Joo-Yong,Ravid, Rivka,Ferrer, Isidro,Yoo, Jong Shin,Kwon, Kyung-Hoon,Park, Young Mok Springer-Verlag 2014 Analytical and Bioanalytical Chemistry Vol.406 No.22
<P>Posttranslational modifications modulate protein function in cells. Global analysis of multiple posttranslational modifications can provide insight into physiology and disease, but presents formidable challenges. In the present study, we used a technique that does not require target enrichment to analyze alterations in the phosphorylation and ubiquitination of proteins from patients with Alzheimer's disease (AD). Guided by our previous findings, we applied three strategies to further our understanding of the dysregulation of posttranslationally modified proteins. We first identified phosphorylation sites by determining peptide pI shifts using OFFGEL. Second, using tandem mass spectrometry, we determined the ubiquitination status of the proteins using an assay for a trypsin digestion remnant of ubiquitination (Gly-Gly). Third, for large-scale discovery, we quantified the global differences in protein expression. Of the proteins expressed in AD tissue at levels of 2.0 or greater compared with controls, 60 were phosphorylated and 56 were ubiquitinated. Of the proteins expressed at levels of 0.5 or lower compared with controls, 81 were phosphorylated and 56 were ubiquitinated. Approximately 98?% of the phosphopeptides exhibited a pI shift. We identified 112 new phosphorylation sites (51.38?%), and 92 new ubiquitination sites (96.84?%). Taken together, our findings suggest that analysis of the alterations in posttranslationally modified proteins may contribute to understanding the pathogenesis of AD and other diseases.</P>
Consequence analysis for nuclear reactors, Yongbyon
Kang, Taewook,Jae, Moosung Atomic Energy Society of Japan 2017 Journal of nuclear science and technology Vol.54 No.2
<P>Since the Fukushima nuclear power plant accidents in 2011, there have been an increased public anxiety about the safety of nuclear power plants in Korea. The lack of safeguards and facility aging issues at the Yongbyon nuclear facilities have increased doubts. In this study, the consequence analysis for the 5-MWe graphite-moderated reactor in North Korea was performed. Various accident scenarios including accidents at the interim spent fuel pool in the 5-MWe reactor have been developed and evaluated quantitatively. Since data on the design and safety system of nuclear facilities are currently insufficient, the release fractions were set by applying the alternative source terms made for utilization in the analysis of a severe accident by integrating the results of studies of severe accidents occurred before. The calculation results show the early fatality zero deaths and latent cancer fatality about only 13 deaths in Seoul. Thus, actual impacts of a radiological release will be psychological in terms of downwind perceptions and anxiety on the part of potentially exposed populations. Even considering the simultaneous accident occurrence in both 5-MWe graphite-moderated reactor and 100-MWt light water reactor, the consequence analysis using the MACCS2 code shows no significant damage to people in South Korea.</P>
요추 척추관 협착증 환자의 양방향 경피적 내시경을 이용한 척추 수술
강태욱(Taewook Kang),이순혁(Soon Hyuck Lee),박시영(Si Young Park) 대한정형외과학회 2019 대한정형외과학회지 Vol.54 No.3
요추 척추관 협착증에서 다양한 방법으로 감압술을 시행하고 있으며, 최근 들어 고식적인 척추관 감압술의 여러 합병증을 최소화하기 위하여 최소 침습적 척추 수술이 시행되고 있다. 단방향 내시경을 이용한 감압술은 구조적으로 한계가 있어 그 사용이 제한적이기 때문에 양방향 내시경을 이용한 감압술을 시행하고 있다. 요추 척추관 협착증에서 양방향 내시경을 이용한 감압술은 안전하게 충분한 감압술을 시행할 수 있는 만족스러운 수술법이다. Lumbar decompressive surgery is a standard surgery for lumbar spinal stenosis. Many surgical techniques have been introduced, ranging from open surgery to percutaneous procedures. Minimally invasive techniques are preferred because of the less postoperative pain and shorter hospital stay. Uniportal percutaneous endoscopic decompression has technical difficulties due to the narrow field. Biportal percutaneous endoscopic decompression is a satisfactory technique that can compensate for the shortcomings and provide sufficient decompression.