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Li, Qian,Wang, Shuyu,Lee, Dong‐,Kyou,Tang, Jianping,Niu, Xiaorui,Hui, Pinhong,Gutowski Jr., William J.,Dairaku, Koji,McGregor, John L.,Katzfey, Jack,Gao, Xuejie,Wu, Jia,Hong, Song‐,You,Wan Wiley 2016 International journal of climatology Vol.36 No.13
<P><B>ABSTRACT</B></P><P>Under the framework of an project ‘Building Asian Climate Change Scenarios by Multi‐Regional Climate Models Ensemble’, the ability of eight regional climate models and two fine‐resolution global climate models to reproduce late 20th century (1981–2000) precipitation climatology is assessed. Future precipitation change (2041–2060) under the A1B scenario is also quantified by applying four different ensemble methods: equal weighting, weighted mean (WM), reliability ensemble averaging (REA) and performance‐based ensemble averaging, after applying fourfold cross‐validation using observation and multi‐model‐simulated precipitation. The results indicate that the ensemble of simulated precipitation outperforms any single RCM in many aspects. Among the four ensemble approaches, the WM and REA methods show better skill in improving the simulation results, and are used for ensemble prediction of regional climate in Asia. Under the A1B scenario, the WM method estimates future precipitation change of approximately 0.2 mm day<SUP>−1</SUP> with less precipitation in northern and western China and northern India, and more precipitation in most other areas in Asia. The future annual precipitation will decrease by 0.1‐0.5 mm day<SUP>−1</SUP> in northern India, Pakistan and the central area of southern China. No significant change is found over eastern Kazakhstan, Mongolia, north‐central and western China.</P>
Yundong Wu,Kanggen Zhou,Shuyu Dong,Wei Yu,Chunsheng Liang 대한환경공학회 2015 Environmental Engineering Research Vol.20 No.4
The industrial-scale biological treatment of Chinese nutgall processing wastewater was conducted with a 200 ㎥ expanded granular sludge bed reactor and a 900 ㎥ bio-contact oxidation reactor. The temperature of the two reactors was controlled under mesophilic conditions (32-40℃), through changing the proportion of the dilution water, which was composed of steam condensation water and residual circulating water. The effluent COD, gallic acid, chroma, total nitrogen, total phosphorus levels and pH of both the expanded granular sludge bed and bio-contact oxidation reactors were monitored. In addition, the redox potential in the expanded granular sludge bed was recorded. The total COD removal efficiency was 87.257% when the influent COD concentration was 14 251±3 148 mg/L-1, and the ratio of wastewater: dilution water was 1:5. The removal efficiencies of gallic acid, chroma, total nitrogen, and total phosphorus were 72.221%, 43.940%, 64.151% and 39.316%, respectively. The effluent pH increased in either the expanded granular sludge bed reactor or the bio-contact oxidation reactor during the operation. The redox potential in the expanded granular sludge bed varied between -367 mV and -435 mV. The results indicate that the combined process was suitable for treating Chinese nutgall processing wastewater.
Xu Ouwen,Wan Shuyu,Yang Jing,Song Hanyang,Xia Ji,Dong Luzheng,Zhu Xiashi 한국탄소학회 2023 Carbon Letters Vol.33 No.2
Novel ionic liquid-functionalized carbon quantum dots (IL-CDs) were prepared by hydrothermal method, and characterized with FT-IR, TEM and XPS. The IL-CDs exhibited narrower particle size distribution with more uniform dispersion and the surface potential changes from negative to positive due to the function of IL. IL-CDs could be quenched (“turned off”) after adding ascorbic acid (AA), and as an “on–off”, fluorescent probe could be established for direct analysis AA. The linear range of AA was 0.34–30.00 μg/mL and the LOD was 0.11 μg/mL. The method was successfully applied to the determination of AA in real samples with satisfactory results.
Choi, Su-jeong,Piao, Shuyu,Nagar, Harsha,Jung, Saet-byel,Kim, Seonhee,Lee, Ikjun,Kim, Sung-min,Song, Hee-Jung,Shin, Nara,Kim, Dong Woon,Irani, Kaikobad,Jeon, Byeong Hwa,Park, Jeen-Woo,Kim, Cuk-Seong Elsevier 2018 Biochemical and biophysical research communication Vol.503 No.3
<P><B>Abstract</B></P> <P>Isocitrate dehydrogenase 2 (IDH2) is an essential enzyme in the mitochondrial antioxidant system, which produces nicotinamide adenine dinucleotide phosphate, and thereby defends against oxidative stress. We have shown that IDH2 downregulation results in mitochondrial dysfunction and reactive oxygen species (ROS) generation in mouse endothelial cells. The redox enzyme p66shc is a key factor in regulating the level of ROS in endothelial cells. In this study, we hypothesized that IDH2 knockdown-induced mitochondrial dysfunction stimulates endothelial inflammation, which might be regulated by p66shc-mediated oxidative stress. Our results showed that IDH2 downregulation led to mitochondrial dysfunction by decreasing the expression of mitochondrial oxidative phosphorylation complexes I, II, and IV, reducing oxygen consumption, and depolarizing mitochondrial membrane potential in human umbilical vein endothelial cells (HUVECs). The dysfunction not only increased mitochondrial ROS levels but also activated p66shc expression in HUVECs and IDH2 knockout mice. IDH2 deficiency increased intercellular adhesion molecule (ICAM)-1 expression and mRNA levels of pro-inflammatory cytokines (tumor necrosis factor [TNF]-α, and interleukin [IL]-1β) in HUVECs. The mRNA expression of ICAM-1 in endothelial cells and plasma levels of TNF-α and IL-1β were also markedly elevated in IDH2 knockout mice. However, p66shc knockdown rescued IDH2 deficiency-induced mitochondrial ROS levels, monocyte adhesion, ICAM-1, TNF-α, and IL-1β expression in HUVECs. These findings suggest that IDH2 deficiency induced endothelial inflammation via p66shc-mediated mitochondrial oxidative stress.</P> <P><B>Highlights</B></P> <P> <UL> <LI> IDH2 deficiency triggers severe mitochondrial dysfunction in HUVECs. </LI> <LI> IDH2 deficiency induces endothelial inflammation by the increased mitochondrial ROS and p66shc expression. </LI> <LI> p66shc mediated IDH2 deficiency-induced inflammatory molecule expression in HUVECs. </LI> </UL> </P>
Yundong Wu,Xihe Xia,Shuyu Dong,Kanggen Zhou 대한환경공학회 2017 Environmental Engineering Research Vol.22 No.3
In this study, we report the industrial application of an efficient technology for the recovery of gallic acid from Chinese nutgall processing wastewater. The recovery of gallic acid by industrial scale extraction and stripping devices was performed, with tributyl phosphate as the extractant and kerosene as the diluent. The results showed that the theoretical extraction stage was four, while the theoretical stripping stage was two. A closed-cycle system was studied for the continuous countercurrent extraction and stripping, with a five-stage extraction device and a three-stage reflux stripping device. The results showed that the multistage extraction-stripping system could steadily run for a long period, the average gallic acid level in the raffinate was 0.85 g·L<SUP>-1</SUP>, and the gallic acid content recovered in the strip liquor was higher than 120 g·L<SUP>-1</SUP>. The average extraction yield of gallic acid was 94.14%. When the strip liquor was used as raw material for production, the average production yield increased by 8.64%. In addition, after extraction, the CODCr in the wastewater decreased by 38.19%, and the biodegradability of wastewater improved by 1.6 times. This study provided a new impetus for the sustainable development of the Chinese nutgall processing industry.
Zhang Yu,Peng Shuyu,Dong Shuang,Wang Jihua,Cao Yu,Ma Yongxi,Wang Chunlin 아세아·태평양축산학회 2024 Animal Bioscience Vol.37 No.5
Objective: This study aimed to investigate the effects of dietary supplementation of a fatty acid-balanced oil, instead of soybean oil, on reproductive performance, nutrient digestibility, blood indexes, milk composition in lactating sows, and fecal microbial composition in piglets. Methods: Twenty-four sows (Landrace×Yorkshire, mean parity 4.96) were randomly allotted to two treatments with twelve pens per treatment and one sow per pen based on their backfat thickness and parity. The experiment began on day 107 of gestation and continued until weaning on day 21 of lactation, lasting for 28 days. The control group (CG) was fed a basal diet supplemented with 2% soybean oil and the experimental group (EG) was fed the basal diet supplemented with 2% fatty acid-balanced oil. Results: The fatty acid-balanced oil supplementation increased (p<0.05) the apparent total tract digestibility of dry matter, crude protein, and gross energy in sows. The lower (p<0.05) serum high-density lipoprotein cholesterol and albumin levels of sows were observed in the EG on day 21 of lactation. Dietary supplementation with the fatty acid-balanced oil decreased the fat content, increased the immunoglobulin G level, and changed (p<0.05) some fatty acid content in milk. Moreover, the fatty acid-balanced oil supplementation changed (p<0.05) the fecal microbial composition of piglets, where the average relative abundance of Spirochaetota was decreased (p<0.05) by 0.55% at the phylum level, and the average relative abundance of some potentially pathogenic fecal microorganism was decreased (p<0.05) at the species level. Conclusion: The fatty acid-balanced oil improved nutrient digestibility, changed the serum biochemical indices and milk composition of sows, and ameliorated the fecal microbial composition of piglets.
Tang, Jianping,Li, Qian,Wang, Shuyu,Lee, Dong‐,Kyou,Hui, Pinhong,Niu, Xiaorui,Gutowski Jr., William J.,Dairaku, Koji,McGregor, John,Katzfey, Jack,Gao, Xuejie,Wu, Jia,Hong, Song‐,You,Wang, Wiley 2016 International journal of climatology Vol.36 No.13
<P><B>ABSTRACT</B></P><P>Under the Asia‐Pacific Network for Global Change (APN) project ‘Building Asian Climate Change Scenarios by Multi‐Regional Climate Models Ensemble’ (RMIP III, Regional Model Intercomparision Project), the simulation results of eight regional climate models (RCMs) and two fine‐resolution global climate models are validated for reproducibility of the current surface air temperature climatology (1981–2000), and are used to generate surface air future temperature projections (2041–2060) over the CORDEX‐EA (A Coordinated Regional climate Downscaling Experiment‐East Asia) domain. Four ensemble methods, namely, the equal weighting, the weighted mean, the reliability ensemble averaging, and the performance‐based ensemble averaging, are employed to generate the multi‐model projection of regional climate change over the region. The results show that the regional temperature ensembles of the present climate obtained from all four methods can outperform a single RCM result in aspects of the spatial distribution as well as the seasonal variation over East Asia. The four ensemble methods are then used to project the regional temperature climatology under the IPCC emission scenario of A1B for 2041–2060. Compared with the control climate of 1981–2000, the annual mean temperature of the future climate (2041–2060) increases 1–2 °C in low latitude areas and 2–3 °C in middle–high latitude areas over Asia.</P>
Nagar, Harsha,Jung, Saet-byel,Ryu, Min Jeong,Choi, Su-Jung,Piao, Shuyu,Song, Hee-Jung,Kang, Shin Kwang,Shin, Nara,Kim, Dong Woon,Jin, Seon-Ah,Jeong, Jin-Ok,Irani, Kaikobad,Jeon, Byeong Hwa,Shong, Minh Mary Ann Liebert, Inc. Publishers 2017 Antioxidants & Redox Signaling Vol. No.
<P>Conclusion: These findings indicate that CRIF1 plays an important role in maintaining mitochondrial and endothelial function through its effects on the SIRT1-eNOS pathway.</P>