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      • 플라스틱 압출공정의 정밀 제어기 설계

        양승옥,신권,조태신,윤경한,김영철 ( Seung Ok Yang,Kwone Shin,Tae Shin Cho,Kyong Han Yun,Young Chol Kim ) 충북대학교 산업과학기술연구소 1994 산업과학기술연구 논문집 Vol.8 No.2

        Abstract_Roman We present a design of high precision controller for the plastic extruder, in which the product is required to maintain the constant weight per meter. Since such a system is continuous process, it is very difficult to measure the output va

      • 지역사회 50세 이상 여성의 요실금에 대한 역학조사

        양승옥 ( Seung Ok Yang ),박영경 ( Young Kyeung Park ),김정희 ( Jeong Hee Kim ) 전북대학교 의과학연구소 2003 全北醫大論文集 Vol.27 No.2

        저자들은 한국 여성의 요실금의 유병률을 추정하기위해 2003년 5월부터 8월사이 전북 진안군 마령면 50세 이상의 여성 612명을 대상으로 하여 설문조사 및 무료검진을 시행하였다. 이상의 지역사회를 대상으로한 본 요실금 역학조사 결과 우리나라도 상당한 요실금환자가 있다는 것을 알수있었다. 이를 바탕으로 요실금에 대한 보건당국의 계몽, 교육, 홍보 및 치료 등의 적절한 대응조치가 필요하리라 생각된다. Purpose: The goals of this study were to estimate the prevalence and relationship between urinary incontinence quality of life in community-dwelling women over 50 years old. Materials and Methods: The study was conducted in a typical farming village of Ma-lung in the southern region of Korea. The community population had 612 women over 50 years old Ma-lung. The interviews using questionnaires regarding general characteristics, obstetric history, disease-related factors, and urinary symptoms including incontinence were undertaken. In addition, physical examination were performed. Results: Of 612 female residents over 50 years old, 311 women were participated in our study. The response rate was 50.8%. The prevalence of urinary incontinence was 60.5%(188/311) of the responders. The prevalence of urinary incontinence for each decade was 60.0%, 70.2%, 56.3% and 45.3% over 50 and up to 89 years of age, respectively. The prevalence of urinary incontinence was 68.1%(111/163) in low or normal weight female (body mass index <25), and 84.8%(28/33) in overweight or obese group (body mass index >_25). The prevalence of stress incontinence was higher in overweight or obese(68.1%) than low or normal weight group(84.8%)(p<0.05). Though number of delivery did not affect the prevalence of urinary incontinence, a good correlation was found between stress urinary incontinence and number of delivery. Conclusions: The prevalence of female urinary incontinence in this study was relatively higher compared to other studies. Most of incontinent women did not recognize the incontinence as a pathological state and consequently, did not visit doctor. Such behavior suggests that they need more information and education toward urinary incontinence. Also, health care providers should pay more close attention for patient who are suffering from urinary incontinence.

      • SCOPUSKCI등재
      • APR1400용 모델 예측 제어 로직에서의 주요 제어변수 변동에 따른 성능 평가

        양승옥(Seung Ok Yang),최유선(Yu Sun Choi),나만균(Man Gyun Na) 대한전기학회 2008 대한전기학회 학술대회 논문집 Vol.2008 No.10

        본 논문에서는 차세대원자로인 APR1400(Advanced Power Reactor 1400)의 출력제어방법으로 모델예측제어 알고리즘을 적용하고, 일일부하추종 운전을 하였을 때 최적의 제어기 구현을 위해 제어 로직의 주요 변수인 예측구간, 제어구간, 모델 차수의 변화에 따른 제어 성능을 평가하였다. 성능 평가는 원자로 출력제어 성능 검증시 사용하는 방법으로 제어대상인 차세대 원자로(APR1400)를 3차원 노심해석 전산코드인 MASTEH(Multipurpose Analyzer for Static and Transient Effects of Reactor)로 시뮬레이션하여 제어 성능을 평가하였다.

      • SCOPUSKCI등재

        아몬드 첨가에 의한 대두의 이소플라본 특성 변화 연구

        양승옥(Seung Ok Yang),장판식(Pahn-Shick Chang),백봉권(Bong Kwon Baek),홍성대(Sung Dae Hong),이재환(Jae Hwan Lee) 한국식품과학회 2007 한국식품과학회지 Vol.39 No.3

        천연소재인 아몬드 첨가에 의한 대두 이소플라본의 특성 변화를 연구하였다. 대두를 침지처리 및 oven-drying 공정을 통해 β-glucosides 함량을 증가시킨 후 아몬드 2.5%첨가 12시간 반응으로 β-glucosides로부터 비배당체를 전환시켜 비배당체의 함량을 날콩에 비해 17.5배 이상 증가시킬 수 있었다. 아몬드 첨가에 의한 genistin 분해 속도 및 genistein 생성속도는 각각의 daidzin 분해속도 및 daidzein 생성속도보다 높았다. The isoflavone distributions of soy samples treated with soaking, oven-drying, and almond additions were determined by high performance liquid chromatography (HPLC). Oven-drying was performed to increase the amount of β-glucoside isoflavones, and almonds were added to convert the β-glucosides into their corresponding aglycones. Oven-drying at 100℃ for 4 hr significantly increased β-glucoside levels and decreased malonyl-β-glucosides, while almond additions of 2.5% and 5.0%, (w/w) significantly increased aglycone contents (p < 0.05) for samples with 12 hr of drying. The rate of increase for genistein from genistin was faster than that of daidzein from daidzin with almond additions. The β-glucosidase activity in the 5.0% added almond soybean samples was significantly higher than in the samples without added almond (p < 0.05). The aglycone content increased from 1.62% in the raw soybeans to 61.55% in the 2.5% added almond soybean samples for 12 hr of incubation. The information from this study could be used to increase the isoflavone aglycone contents of soybeans by using natural products such as almonds, without organic solvent additions or micro-organism fermentation.

      • 복압성요실금 환자에서 전기자극을 이용한 골반근육운동의 효과

        양승옥 ( Seung Ok Yang ),박영경 ( Young Kyung Park ),김정희 ( Jeong Hee Kim ) 전북대학교 의과학연구소 2004 全北醫大論文集 Vol.28 No.1

        Purpose: We evaluated the results of the pelvic floor muscle training using a electrical stimulation in the treatment of the patients with stress urinary incontinence. Materials and Methods: 38 women (mean age 57.3 years) with stress urinary incontinence were assigned to pelvis floor muscle training program. Nine of them were grade 1, seventeen were grade 2, Electrical stimulation of 2 times/week, for a total of 6 times were assigned. We recommended home exercise which included 3 sets of 8 to 12 slow velocity maximal contractions sustained for 6 to 8 seconds each, performed 3 to 4 times a week and continued for at least 3 months. We interviewed the patients to obtain the results 3 months after treatment. Results: Of the 38 patients with good compliances, the overall success rate for this treatment was 76.3%(29/38); nine(21.1%) were cured and 21(55.3%) improved. Conclusions: Pelvic floor muscle training using a electrical stimulation for 3 months were effective in the treatment of the patients with stress urinay incontinence.

      • 누에-달맞이꽃 종자유 투여가 수컷 마우스의 성기능에 미치는 영향

        양승옥 ( Seung Ok Yang ),박영경 ( Yong Kyeung Park ),신숙정 ( Sook Jeong Shin ),이정호 ( Jeong Ho Lee ) 전북대학교 의과학연구소 2003 全北醫大論文集 Vol.27 No.1

        누에제품(SWP)이 정력증강제로서 시판되고 있으나 이가 과연 성기능 증강기능이 있는가는 아직까지 불명하다. 이에 본 실험은 이를 실험적으로 입증하고자 하였으며, 아울러, PGE가 발기에 관여하며 PGE의 전구물질이 다량 함유되어 있다고 알려진 달맞이꽃 종자유(EPO)가 성기능에 어더한 영향을 미치는가를 밝히기 위하여 계획되었다. 실험대상 동물은 ICR계 수컷마우스를 사용하였으며, 공시한 세포는 HUVE 세포와 마우스로부터 직접 적출한 음경해면조직의 평활근을 사용하였다. 마우스에의 SWP 및 EPO의 투여는 경구삽관에 의하여 1일 1회 14일간 투여하였다. 성기능 증강효과의 평가는 고환의 무게, 교미횟수, 혼숙시킨암 마우스 질외부의 정충양성율, 혈증 활성 testosterone의 농도, 음경 평활근의 PGE농도, 혈증 cGMP의 농도 그리고 혈관내피 세포의 NO생산능 등을 측정하여 실시하였다. 그 결과 다음과 같은 성정을 얻었다. 1. 시료의 투여에 의하여 체중이 대조에 비하여 다소 증가되었다. 2.고환의 무게는 시료 투여군에서 모두 증가되었는데 그 증가의 정도는 EPO 군보다 SWP 투여군에서 더욱 높았다. 3. 교미횟수는 대조에 비하여 SWP군에서는 다소 증가되었으나, EPO군에서는 현저히 증가되었다. 4. 정충 양성율은 시료 투여군 모두에서 대조군보다 약 2배 높았다. 5. 혈중 활성 testosterone의 농도는 EPO군에서는 2.3배 증가되었으나 SWP투여군과 대조군간에는 유의한 차이를 보이지않았다. 6. 음경평활근의 PGE생산능은 SWP에 의해서는 영향을 받지 않았지만 EPO군에 서는 유의하게 증가되었다. 7. 혈중 cGMP 농도는 시료 투여군 모두에서 증가되었다. 8. 혈관내피세포의 NO 생산능은 EPO에 의해서는 유의한 영향을 받지 않았지만 SWP으로 처리하면 유의하게 항진되었다. 이상의 결과는 SWP 및 EPO 모두 수컷마우스의 성기능을 NO, cGMP, PGE, 및활성 testosterone 생산 등 여러 경로를 통하여 증강시킴을 제시한다. Objectives: The present study was undertaken to evaluate the effect of silk worm powder (SWP) and evening primrose oil (EPO) on the male sexual functions such as increment testis weight, number of complete intromissions and mating, testosterone and cGMP levels in serum, prostaglandin levels of penile corpus cavernosum smooth muscle cells and NO-productive activity of endothelial cells. Methods: ICR male mice with same body weight and age were randomly divided into several experimental and control groups. SWP (daily 50 mg/mouse) or EPO (daily 0.5mg/mouse) was orally intubated for 28 consecutive days to experimental groups, and same vol. of vehicle to control group. The weight of body and testis were weighed at the time interval. On day 14, 30 minutes after dose, 2 virgin female mice were placed with 1 male mouse, and the number of complete intromissions of each male mouse in 3 hours was recorded. In an assessment of 1 day of mating, each male mouse was cohabited with 5 estrous female mice overnight, and then the number of sperm-positive females was recorded. Blood was obtained from mice on day 14 of dose, and serum concentrations of free testosterone and cGMP were measured by ELISA. On day 14, the penis was removed from each animals by cutting the crura corpus cavernosum, the corpus cavernosum were then excised and squeezed, and prostaglandin level of each sup was measured by ELISA. The HUVE cells were stimulated with ionomycin, and cultured for 48hrs in the presence of SWP and/or EPO, and then the level of NO in culture sup was measured. Results: The weight of body and testis of SWP and/or EPO treated mice was somewhat increased than that of control. The number of complete intromissions during the 3-hour period was 15.2 2.1, 23.2 2.5, 41.3 3.6, 37.1 2.9 for the control group, SWP group, EPO group, and SWP+EPO combined group, respectively. The number of sperm-positive females increased in experimental groups, as compared with that of control. The serum concentrations of testosterone was somewhat increased in SWP group and SWP+EPO group, however, was significantly elevated in EPO treated group. The releasing amounts of prostaglandin of penile corpus cavernosum was almost same levels in SWP-treated mice, but was markedly increased in EPO group. The serum cGMP level was significantly increased in all experimental groups. The NO production of ionomycin-stimulated HUVE cells was increased only when SWP was added into cultures. Conclusions: Oral administration of SWP and EPO enhanced the sexual function of male mice, as evidenced by an increase in the testis weight, number of complete intromissions and mating, serum testosterone and cGMP levels, productive activity of prostaglandin of penile smooth muscle cells, and NO production of endothelial cells. The present study suggests that both SWP and EPO can be developed as a tonic improving sexual function.

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