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Association between genetic variants in pre-microRNAs and survival of early-stage NSCLC.
Hong, Mi Jeong,Choi, Yi Young,Jang, Ji-Ae,Jung, Hye-Jin,Lee, Shin Yup,Lee, Won Kee,Yoo, Seung Soo,Lee, Jaehee,Cha, Seung Ick,Kim, Chang Ho,Lee, Eungbae,Jeon, Hyo-Sung,Son, Ji Woong,Park, Jae Yong Lippincott Williams Wilkins 2013 Journal of thoracic oncology Vol.8 No.6
<P>MicroRNAs (miRNAs) are an abundant class of small non-protein-coding RNAs that function as negative gene regulators. Recent evidence indicates that altered miRNA expression plays an important role in the initiation and progression of lung cancer. Single nucleotide polymorphisms (SNPs) in pre-miRNAs could alter miRNAs processing, or expression, and hence, could influence the prognosis of lung cancer. To test this hypothesis, we evaluated the effects of four SNPs in pre-miRNAs (pre-miR-146a rs2910164, pre-miR-149 rs2292832, pre-miR-196a rs11614913, and pre-miR-499 rs3746444) on the survival outcomes of patients with early-stage non-small-cell lung cancer (NSCLC).</P>
Leaf and Stem Blight on Columbine and Bleeding Heart Caused by Streptobotrys caulophylli
Hong, Sung-Kee,Kim, Wan-Gyu,Cho, Weon-Dae,Kim, Hong-Gi The Korean Society of Plant Pathology 2004 Plant Pathology Journal Vol.20 No.3
A survey on ornamental diseases in 2000 and 2001 showed frequent occurrence of blight symptoms on leaves and stems of columbine and bleeding heart in botanical gardens of Gangwon and Chungnam provinces in Korea. A total of 65 isolates of Streptobotrys sp. were obtained from the infected leaves and stems of the two plants. All isolates were identified as Streptobotrys caulophylli based on their morphological and cultural characteristics. Blight symptoms were induced on leaves of the two plants by artificial inoculation with the isolates. This is the first report that S. caulophylli causes leaf and stem blight on columbine and bleeding heart in the world.
Occurrence of Gray Mold in Freesia and Gladiolus Caused by Botrytis gladiolorum in Korea
Hong, Sung-Kee,Kim, Wan-Gyu,Cho, Weon-Dae,Kim, Hong-Gi The Korean Society of Plant Pathology 2003 Plant Pathology Journal Vol.19 No.2
Gray mold severely occurred up to 50% in freesia and gladiolus grown in the fields and greenhouses in Korea from 1998 to 2000. Symptoms appeared as spot and blight on loaves and flowers of infected plants. A total of 25 isolates was obtained from infected plant parts. All the isolates were identified as Botrytis gladiolorum based on their morphological and cultural characteristics. Gray mold symptoms similar to those observed in the fields and greenhouses were induced on the plants of freesia and gladiolus by artificial inoculation with four isolates of the fungus. This is the first report of gray mold of freesia caused by B. gladiolorum in Korea.
Hong, Soon-Ho,Kim, Yong-Duk,Na, Sang-Jun,Lee, Kee Ook,Park, Yun Kyung,Yoon, Bora The Korean Society of Clinical Neurophysiology 2017 Annals of Clinical Neurophysiology Vol.19 No.2
Trigeminal neuralgia (TN) is generally characterized by lancinating, unilateral, paroxysmal pain occurring in the distribution of the fifth cranial nerve. TN is diagnosed clinically based on the typical patient history, negative findings in a neurologic examination, and the response to medication. Idiopathic TN is the most common type, but TN can result from vascular malformation, compression, trauma, neoplasm, multiple sclerosis, or inflammation. We report a TN case diagnosed as recurrent trigeminal neuritis of the maxillary branch confirmed by magnetic resonance imaging.
Occurrence of Tulip Fire Caused by Botrytis tulipae in Korea
Hong, Sung-Kee,Kim, Wan-Gyu,Cho, Weon-Dae,Kim, Hong-Gi The Korean Society of Plant Pathology 2002 Plant Pathology Journal Vol.18 No.2
Severe spotted lesions were observed on tulip plants grown in Asan, Yongin, and Icheon areas in Korea during a disease survey in 2000 and 2001. Diseased plants with severe symptoms were blighted and rotted at the late stage of disease development. A total of 15 isolates was obtained from the infected plant parts of tulip. All the isolates were identified as Botrytis tulipae based on their morphological and cultural characteristics. Three isolates of B. tulipae were tested for their pathogenicity to tulip by artificial inoculation. Spotted lesions similar to those observed in the fields were induced on tulip leaves. This is the first report of tulip fore disease caused by B. tulipae in Korea.
Giant Adrenal Myelolipoma : Report of a Case with Review of the Literature
Hong, Ran,Suh, Chae-Hong,Jeon, Ho-Jong,Kee, Keun-Hong,Lim, Sung-Chul,Lee, Mi-Ja 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1
Adrenal myelolipoma is an unusual, nonfunctiomng benign tumor composed of mature fat and hematopoietic tissue. Most cases of adrenal myelolipomas are clinically silent and found incidentally at autopsy or radiological examinations done for other purposes. Their size is usually less than 5 ㎝ and they are managed non-operatively. We report a case of a surgically treated, giant adrenal myelolipoma in a 60-year-old man who presented with abdominal discomfort and we present a review of the literature.
( Sang Hyung Lee ),( Woo Jin Lee ),( Hong Il Cho ),( Kwang Hee Won ),( Sung Eun Chang ),( Mi Woo Lee ),( Jee Ho Choi ),( Kee Chan Moon ),( Chong Hyun Won ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.2
Background: Presenting study estimate the degradation of hyarulonic acid (HA) filler in vivo using rat model to evaluate the longevity of HA fillers depending on injection depth. Objectives: This quantitative analysis demonstrated that HA filler has a longer longevity when injected in deep layer of tissue. Methods: Each 3 Sprague-Dawley rats were assigned to groups based on the sampling timepoints. Four intradermal injections on the one side of back plus four subcutaneous injections on the other side of back of rats was made. Histologic specimens from injected site were obtained at 2 weeks, 5 weeks, 9 weeks, 13 weeks, 20 weeks and 33 weeks after initial implantation. Volumetric analysis using histologic specimen was performed. Results: Volumetric analysis with histologic specimen demonstrated the difference in degradation rate depending on injection depth. Although volume ratio decreased over time in subdermal injection site, subdermal injected site maintained a greater volume ratio than it of intradermal injection site for the duration of the experiment. Time to half of original implant volume was 13 weeks (intradermal site) and 20 weeks (subdermal site) after initial injection, respectively. Conclusion: Presenting study is the first to demonstrate histological change of implanted HA filler materials over time and compare the duration of materials depending on injection depth.