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Jin-Rui Wei,Kun Liu,Faquan Lin,Chunping He,Xuan Luo,Jiajia Zou,Wei He,Wenqian Nong,Cui-Wu Lin 한국응용생명화학회 2016 Applied Biological Chemistry (Appl Biol Chem) Vol.59 No.2
Four hydroxybenzamide derivatives were synthesized from protocatechuic acid. The antioxidant activities of these derivatives were evaluated in vitro using DPPH radical scavenging and reducing power assays. In addition, these compounds were subjected to a chromogenic thrombin-inhibitory assay using Chromozym-TH as the substrate. The anticancer effects of these derivatives were also investigated using the MTT assay in three human cancer cell lines. Four derivatives exhibited excellent DPPH radical scavenging activity and redox potential. Their highly inhibitory effect against thrombin may allow them to be utilized as novel micromolecule thrombin inhibitors. Furthermore, four derivatives demonstrated different inhibitory activities in three human cancer cell lines but showed minimal harmful effects on normal HUVEC cells. Therefore, hydroxybenzamide derivatives indicate the superior antioxidant, thrombin-inhibitory, and anticancer activities along with the excellent biocompatibility, which have the potential application in therapeutic interventions and disease prevention of cancer, thrombotic diseases, and aging.
The Investigation on Thermal Aging Characteristics of Oil-Paper Insulation in Bushing
Rui-jin Liao,En-de Hu,Li-jun Yang,Zuo-ming Xu 대한전기학회 2015 Journal of Electrical Engineering & Technology Vol.10 No.3
Bushing is the key link to connect outer and inner insulating systems and also the essential electric accessory in electric power system, especially in the high voltage engineering (AC 1000kV, DC 800kV). This paper presented the experimental research of thermal aging characteristic of oilpaper insulation used in bushing. A thermally accelerated aging experiment at 90℃ was performed. The bushing models containing five layers of paper were sealed into the aging vessels and further aged for 250 days. Then several important parameters associated with the aging were observed and evaluated. The results showed that the degree of polymerization (DP) of papers gradually decreased. The DP values of outermost layer and middle layer fit well into the second-order kinematic model and first-order kinematic model, respectively. Less deterioration speed of the inter-layer paper than outer layer was confirmed by the variation of DP. Hydrolysis was considered as the main cause to this phenomenon. In addition, the logarithm of the furfural concentrations in insulation oil was found to have good linear relationship with DP of papers. Interestingly, when the aging time is about 250 days and DP is 419, the aging process reaches an inflection point at which the DP approaches the leveling off degree of polymerization (LODP) value. Both tanδ and acid number of oils increased, while surface and volume resistivity of papers decreased. The obtained results demonstrated that thermal aging and moisture absorbed in papers brought great influence to the degradation of insulating paper, leading to rapid decrease of DP and increase of the tanδ . Thus, the bushing should be avoided from damp and real-time monitoring to the variation of tanδ and DP values of paper is an effective way to evaluate the insulation status of bushing.
Antioxidant Activity of Water Extract from the Cultured Mycelia of Phellinus Baumii
Jin Won Hyun,Jinny Park,Kyoung Ah Kang,Rui Zhang,Mei Jing Piao,Soyoon Park,Jin Seo Park,Young Kook Kim,Mun Chaul Rho,Hyun Sun Lee 대한암예방학회 2006 Journal of cancer prevention Vol.11 No.4
The antioxidant property of cultured mycelia of Phellinus baumii was investigated. The water-soluble extract isolated from these mycelia showed intracellular reactive oxygen species, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and lipid peroxidation inhibitory activities. This radical scavenging activity of extract protected cell viability of Chinese hamster lung fibroblast (V79-4) cells exposed to H2O2. Furthermore, water extract reduced the apoptotic cells induced by H2O2, as demonstrated by the decreased number of sub G1 hypo-diploid cells and apoptotic body formation and it increased the activities of cellular antioxidant enzymes, superoxide dismutase and catalase. Taken together, these findings suggest that mycelia of P. baumii exhibit antioxidant property. (Cancer Prev Res 11, 329-335, 2006)
Morphology Control of Tungsten Oxide Thin Films in an Aerosol Flame Deposition System
Ding, Jin-Rui,Yoon, Sang-Hyeok,Kim, Kyo-Seon American Scientific Publishers 2017 Journal of Nanoscience and Nanotechnology Vol.17 No.4
<P>Tungsten oxide thin film has been found great potential use in various applications such as smart window, gas sensor and photoelectrochemical cell due to their unique electrochromic, gas-chromic and electrochemical properties. The thin film morphology has been considered as an efficient limiting aspect for its performance. In this work, we successfully prepared tungsten oxide thin films with distinctive nanostructures on conductive glass in a flame vapor deposition process. The morphology of tungsten oxide thin films could be controlled by adjusting various process variables, including methane-oxygen ratio, deposition height and support substrate temperature. 1-D nanowires and nanotubes could be obtained in fuel rich flame at high substrate support temperature and 3-D nanocolumns could be easily formed in fuel lean flame. This work offers a rapid, economic approach for the growth of tungsten oxide thin film with controlled morphology.</P>
The Investigation on Thermal Aging Characteristics of Oil-Paper Insulation in Bushing
Liao, Rui-jin,Hu, En-de,Yang, Li-jun,Xu, Zuo-ming The Korean Institute of Electrical Engineers 2015 Journal of Electrical Engineering & Technology Vol.10 No.3
Bushing is the key link to connect outer and inner insulating systems and also the essential electric accessory in electric power system, especially in the high voltage engineering (AC 1000kV, DC 800kV). This paper presented the experimental research of thermal aging characteristic of oil-paper insulation used in bushing. A thermally accelerated aging experiment at 90℃ was performed. The bushing models containing five layers of paper were sealed into the aging vessels and further aged for 250 days. Then several important parameters associated with the aging were observed and evaluated. The results showed that the degree of polymerization (DP) of papers gradually decreased. The DP values of outermost layer and middle layer fit well into the second-order kinematic model and first-order kinematic model, respectively. Less deterioration speed of the inter-layer paper than outer layer was confirmed by the variation of DP. Hydrolysis was considered as the main cause to this phenomenon. In addition, the logarithm of the furfural concentrations in insulation oil was found to have good linear relationship with DP of papers. Interestingly, when the aging time is about 250 days and DP is 419, the aging process reaches an inflection point at which the DP approaches the leveling off degree of polymerization (LODP) value. Both tanδ and acid number of oils increased, while surface and volume resistivity of papers decreased. The obtained results demonstrated that thermal aging and moisture absorbed in papers brought great influence to the degradation of insulating paper, leading to rapid decrease of DP and increase of the tanδ. Thus, the bushing should be avoided from damp and real-time monitoring to the variation of tanδ and DP values of paper is an effective way to evaluate the insulation status of bushing.
Antioxidant and Cytotoxicity Effects of Luteolin
Park Jin-Ny,Kang Kyoung-Ah,Zhang Rui,Piao Mei Jing,Park So-Yoon,Kim Ju-Sun,Kang Sam-Sik,Hyun Jin-Won Korean Society of ToxicologyKorea Environmental Mu 2006 Toxicological Research Vol.22 No.4
Flavonoids are polyphenolic compounds that are ubiquitous in plants. They have been shown to possess a variety of biological activities, such as antioxidant and anticancer. Reactive oxygen species (ROS) lead to damages of cellular molecules and it is the one of various factors to induce cancer. The one of flavonoids, Luteolin, was found to scavenge 1,1-diphenyl-2-piculhydrazyl (DPPH) radical and intracellular reactive oxygen species (ROS). Moreover luteolin showed protection on hamster lung fibroblast cells (V79-4 cell) damage induced by $H_2O_2$. And then it was investigated whether it may show cytotoxicity effect against various cancer cells by MTT, Luteolin at $10{\mu}g/ml$ showed the cell viability of 63.2%, 34.7%, 18.4% and 71.4% against NCl-H460, HeLa, U937 and MCF-7, respectively. As a result, luteolin shows more sensitive to U937 cells among the tested cancer cell lines. In summary, luteolin has antioxidant and cytotoxicity effect or various cancer cell lines.