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Reznikov Alexander,Sachynska Olga,Lymareva Anna,Faliush Oksana 한국독성학회 2021 Toxicological Research Vol.37 No.2
Environmental chemical pollutants that interfere with hormonal homeostasis or hormone signaling are the relevant agents inducing congenital or postnatally developed reproductive abnormalities in human beings, wild and domestic animals. In this study, we are examining reproductive effects of prenatal exposure of male rats to a low dose di-n-butylphthalate (DBP). Wistar female rats were given intragastrically DBP at a daily dose of 100 mg/kg b.w. during 15th–21st days of pregnancy. Anogenital distance (AGD) in male offspring decreased on postnatal day (PND) 2 followed by its normalization on PND 7 and 10. There were no other visible teratogenic lesions in the newborns. The testicle descent into scrotum of control males occurred on PND 38.5 ± 0.1, while in DBP group it accelerated by 5.3 days on the average. At the age of 6 months, DBP-exposed animals exhibited double increase of blood plasma testosterone level as compared to controls, and hyperactive male sexual behavior in the presence of receptive female. The duration of latent periods of the first mount and the first intromission, as well as post-ejaculatory refractory period, have been shortened; the number of mounts with intromission and the number of ejaculations increased significantly. Histological examination of the testes indicated activation of Leydig cells. The female-type sexual behavior as evaluated by appearance of lordosis of orchidectomized and primed with estradiol and progesterone 10-month-old males in response to mount or approach of sexually active normal male was enhanced in DBP-group. Both 10-month-old and aging males (18 months), castrated and hormone-primed, displayed homosexual type of behavior. Prenatal low dose DBP caused in 18-month-old males premature atrophy of the testes and accessory sexual glands, increased number of Leydig cell adenomas, a twice decrease of plasma testosterone level and exhausting of sexual potency. We concluded that prenatal exposition of male rats to low dose DBP determines epigenetic alterations of programming of sex brain differentiation and regulation of testicular steroidogenesis that leads to reproductive disorders and accelerated aging of reproductive system.
Alex Ruderman,Boris Reznikov,Steven Thielemans 전력전자학회 2011 ICPE(ISPE)논문집 Vol.2011 No.5
Natural voltage balancing dynamics analysis for flying capacitor converter may be carried out in time domain using switched systems analysis technique based on stitching analytical solutions for consecutive switching subintervals. In conjunction with the small parameter assumption, it allows obtaining closed-form approximate analytical solutions. PWM induced eddy current iron core loss mechanism that is accounted for in equivalent scheme by a large parallel resistance speeds up natural voltage balancing dynamics. Presented simple analytical solutions for 3- and 4-level single-leg flying capacitor converter reveal the dependences on load parameters, carrier frequency, and normalized DC voltage command (AC modulation index).
Mechanism of Formation of Three Dimensional Structures of Particles in a Liquid Crystal
West, John L.,Zhang, Ke,Liao, Guangxun,Reznikov, Yuri,Andrienko, Denis,Glushchenko, Anatoliy V. The Korean Infomation Display Society 2002 Journal of information display Vol.3 No.3
In this work we report methods of formation of three-dimensional structures of particles in a liquid crystal host. We found that, under the appropriate conditions, the particles are captured and dragged by the moving isotropic/nematic front during the phase transition process. This movement of the particles can be enhanced significantly or suppressed drastically with the influence of an electric field and/or with changing the conditions of the phase transition, such as the rate of cooling. As a result, a wide variety of particle structures can be obtained ranging from a fine-grained cellular structure to stripes of varying periods to a course-grained "root" structures. Changing the properties of the materials, such as the size and density of the particles and the surface anchoring of the liquid crystal at the particle surface, can also be used to control the morphology of the three-dimensional particle network and adjust the physical properties of the resulting dispersions. These particle structures may be used to affect the performance of LCD's much as polymers have been used in the past.
Preparation of ferroelectric nanoparticles for their use in liquid crystalline colloids
Atkuri, H,Cook, G,Evans, D R,Cheon, C-I,Glushchenko, A,Reshetnyak, V,Reznikov, Yu,West, J,Zhang, K Institute of Physics Publishing in association wit 2009 Journal of optics A, Pure and applied optics Vol.11 No.2
<P>In this paper we summarize our many years of experience in the preparation and optimization of stable colloids of ferroelectric nanoparticles dispersed in an isotropic carrier and in a liquid crystal host. The colloids are of interest for use in electro-optic devices, photorefractive hybrids and nonlinear optical elements. We also outline some of the most interesting features the nanoparticles bring to liquid crystals, along with the potential of these relatively new colloids.</P>
감광성 도판트를 이용한 풀컬러 구현 가능 반사형 콜레스테릭 액정
박서규,김정수,조희석,권순범,유리레즈니코프,Park, Seo-Kyu,Kim, Jeong-Soo,Cho, Hee-Suck,Kwon, Soon-Bum,Reznikov, Yuri 한국전기전자재료학회 2008 전기전자재료학회논문지 Vol.21 No.5
In order to make full color cholesteric displays, color filter-less R, G, B sub-pixel structured cholesteric LC cells have been studied. To make R, G, B colors, UV induced pitch variant chiral dopant was added to cholesteric LC mixtures. The concentration of the photo-sensitive chiral dopant was adjusted so that the initial state showed blue color and the color was changed from blue to green and red with increase of UV irradiation to the cholesteric cells. To prevent the mixing of R, G, B reflective sub-pixel liquid crystals, separation walls were formed using negative photo resister in boundary area between sub-pixels, Through the optimization of the material concentrations and UV irradiation condition, vivid R, G, B colors were achieved.