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Quan Hai Nguyen,Phung Dinh Le,Channy Chim,Ngoan Duc Le,Veerle Fievez 아세아·태평양축산학회 2019 Animal Bioscience Vol.32 No.4
Objective: Research was conducted to test the effect of including fiber-rich feedstuffs in practical pig diets on nutrient digestibility, nitrogen balance and ammonia emissions from slurry. Methods: Three Vietnamese fiber sources were screened, namely cassava leaf meal (CL), cassava root residue (CR), and tofu by-product (TF). Accordingly, a control diet (Con) with 10% of dietary non-starch polysaccharides (NSP) and three test diets including one of the three fiber-rich feedstuffs to reach 15% of NSP were formulated. All formulated diets had the same level of crude protein (CP), in vitro ileal protein digestible and metabolisable energy, whereas the in vitro hindgut volatile fatty acid (VFA) production of the test diets was 12% to 20% higher than the control diet. Forty growing barrows with initial body weight at 28.6±1.93 kg (mean±standard deviation) were allocated to the four treatments. When pigs reached about 50 kg of body weight, four pigs from each treatment were used for a nitrogen balance trial and ammonia emission assessment, the remaining six pigs continued the second period of the feeding trial. Results: The TF treatment increased fecal VFA by 33% as compared with the control treatment (p = 0.07), suggesting stimulation of the hindgut fermentation. However, urinary N was not significantly reduced or shifted to fecal N, nor was slurry pH decreased. Accordingly, ammonia emissions were not mitigated. CR and CL treatments failed to enhance in vivo hindgut fermentation, as assessed by fecal VFA and purine bases. On the contrary, the reduction of CP digestibility in the CL treatment enhanced ammonia emissions from slurry. Conclusion: Dietary inclusion of cassava and tofu byproducts through an increase of dietary NSP from 10% to 15% might stimulate fecal VFA excretion but this does not guarantee a reduction in ammonia emissions from slurry, while its interaction with protein digestibility even might enhance enhanced ammonia emission.
( Le Quan Qiu ),( Wei Jian Wang ),( Wei Hong Zhong ),( Li Zhong ),( Jian Jun Fang ),( Xuan Zhen Li ),( Shi Jin Wu ),( Jian Meng Chen ) 한국미생물 · 생명공학회 2011 Journal of microbiology and biotechnology Vol.21 No.5
Coenzyme Q10 (CoQ10) is a widely used supplement in heart diseases treatment or antioxidative dietary. The microbial production of CoQ10 was enhanced by addition of solanesol and novel precursors recovered from waste tobacco. The novel precursors were separated by silica gel and identified as α-linolenic acid (LNA) and butylated hydroxytoluene (BHT) based on the effect on CoQ10 production and GC-MS. The effects of novel precursors on CoQ10 production by Sphingomonas sp. ZUTE03 were further evaluated in a two-phase conversion system. The precursor`s combination of solanesol (70mg/l) with BHT (30mg/l) showed the best effect on the improvement of CoQ10 yield. A maximal CoQ10 productivity (9.5 mg l-1 h-1) was achieved after 8h conversion, with a molar conversion rate of 92.6% and 92.4% on BHT and solanesol, respectively. The novel precursors, BHT and LNA in crude extracts from waste tobacco leaves, might become potential candidates for application in the industrial production of CoQ10 by microbes.
Decentralization with regional balanced policies in Vietnam after the “Doi Moi”
Le Quan 한국지역개발학회 2019 한국지역개발학회 학술대회 Vol.2019 No.10
‘Doi moi’ or Renovation in Vietnam after 1986 marked a mile stone in a process of changes towards market economy that has brought Vietnam from a low-income and less developed country into a middle-income developing country. This Renovation has the impacts on the policies for regional development in Vietnam, especially on the issue of giving more power to the local government, creating the foundation for the decentralization process. Besides the achievements, the decentralization process in Vietnam also need adjustment to have the balanced policy for different regions of Vietnam.
Competency Gap in the Labor Market: Evidence from Vietnam
LE, Quan Thai Thuong,DOAN, Tam Ho Dan,NGUYEN, Quyen Le Hoang Thuy To,NGUYEN, Doang Thi Phuc Korea Distribution Science Association 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.9
The relationship between education and work is of the greatest concern to individuals and society because they are the key drivers of growth and development. In the context of Industry 4.0, labor and educators are facing the challenges of big changes in the workplace. How to prepare undergraduate students for the world of employment has become the most important mission of higher education providers. This paper explored the competency gap in the labor market in Vietnam from the perspective of employees who have been dissatisfied with the current status. First, a qualitative method with the Delphi technique was applied to confirm this consensus in an employees' competency model. Then, the satisfaction level for each competency criterion was explored by applying the advance quantitative method, namely, best non-fuzzy performance approach. Lifelong learning was ranked first, followed by creativity and innovation, foreign languages, expertise and digitalization, adaptability, and finally, organizing and managing ability. Critical thinking and problem-solving were perceived to have the biggest gap. The order of competency satisfaction is useful in explaining the mismatch between education quality and labor market demand. The findings provide valuable guidelines for education managers who seek to bridge the competency gap and improve education quality.
Quan Dao-Van(권다어반),Le Tat-Thang(레덧탕),Sung Hae-Jin(성해진),Park Min-Won(박민원),Yu In-Keun(유인근) 한국산업정보학회 2018 한국산업정보학회논문지 Vol.23 No.1
이 논문에서는 대 전류, 고온 초전도 직류 리액터를 위한 전도 냉각 시스템의 구조 설계에 대해 논의하고자 한다. 초전도 자석, 보 빈, 전류 리드, 고정용 구조물 그리고 열 교환기가 포함된 전도 냉각 시스템 부품의 크기를 3D CAD 프로그램을 사용하여 계산하였다. 또한, 최적의 설계 변수를 결정하고 열적-기계적 특성을 분석하기 위해서 유한 요소법 모델을 제작하였다. 리액터 자석의 운전 전류와 인덕턴스는 각각 1,500 A 400 mH이며, 이에 따른 극저온 냉동기의 냉각 용량을 결정하기 위해 초전도 직류 리액터에서 발생하는 열 부하를 계산하였다. 또한, 대 전류가 흐르는 1 단부전도 냉각 시스템의 작동 테스트를 수행하였다. 구리 바는 40 K까지 냉각되었고 초전도 리드는 안정적으로 작동했다. 실험 결과로써, 1 단부 영역의 총 열 부하는 190 W였다. 본 연구 결과는 상용 초전도 직류 리액터의 설계 및 제조에 있어 효과적으로 활용 될 것이다. This paper discusses a structure design and thermal analysis of cryogenic conduction cooling system for a high current HTS DC reactor. Dimensions of the conduction cooling system parts including HTS magnets, bobbin structures, current leads, support bars, and thermal exchangers were calculated and drawn using a 3D CAD program. A finite element method model was built for determining the optimal design parameters and analyzing the thermo-mechanical characteristics. The operating current and inductance of the reactor magnet were 1,500 A, 400 mH, respectively. The thermal load of the HTS DC reactor was analyzed for determining the cooling capacity of the cryo-cooler. Hence, we carried out the operating test of conduction cooling system of the 1st stage area with high current flow. The cooper bars was cooled down to 40 K and HTS leads operated stably. As a experiment result, the total heat load of the 1st stage area is 190 W. The study results can be effectively utilized for the design and fabrication of a commercial HTS DC reactor.
Bioconversion of Ginsenoside Rd into Compound K by Lactobacillus pentosus DC101 Isolated from Kimchi
Quan, Lin-Hu,Cheng, Le-Qin,Kim, Ho-Bin,Kim, Ju-Han,Son, Na-Ri,Kim, Se-Young,Jin, Hyun-O,Yang, Deok-Chun The Korean Society of Ginseng 2010 Journal of Ginseng Research Vol.34 No.4
Ginsenosides are the principal components responsible for the pharmacological and biological activities of ginseng. Ginsenoside Rd was transformed into compound K using cell-free extracts of food microorganisms, with Lactobacillus pentosus DC101 isolated from kimchi (traditional Korean fermented food) used for this conversion. The optimum time for the conversion was about 72 h at a constant pH of 7.0 and an optimum temperature of about $30^{\circ}C$. The transformation products were identified by thin-layer chromatography and high-performance liquid chromatography, and their structures were assigned using nuclear magnetic resonance analysis. Generally, ginsenoside Rd was converted into ginsenoside F2 by 36 h post-reaction. Consequently, over 97% of ginsenoside Rd was decomposed and converted into compound K by 72 h post-reaction. The bioconversion pathway to produce compound K is as follows: ginsenoside Rd$\rightarrow$ginsenoside F2$\rightarrow$compound K.
Le, Vu Ngoc Han,Zhao, Yan,Cho, Chong Woon,Na, MinKyun,Quan, Khong Trong,Kim, Jang Hoon,Hwang, Sung Yeoun,Kim, Sang Wook,Kim, Kyung Tae,Kang, Jong Seong Elsevier 2018 Journal of chromatography. B, Analytical technolog Vol.1102 No.-
<P><B>Abstract</B></P> <P>Nardostachyos Radix et Rhizoma (NR) is a valuable medicinal herb widely used in Korea, India, and China for the treatment of many diseases. Desoxo-narchinol A (DA) and nardosinonediol (ND) are the two main bioactive compounds belonging to the sesquiterpene group. Desoxo-narchinol A possesses anti-inflammatory activity while ND exhibits anti-depressant and cardioprotective activities. A pharmacokinetic study is important to decide whether the isolated compounds or the NR extract have better pharmacological activity. Hence, we developed an analytical method for studying the pharmacokinetics of DA and ND after oral administration of the pure compounds and herbal extract. An optimized liquid chromatography-mass spectrometry method (LC-MS/MS) with solid-phase extraction (SPE) for sample preparation was developed. A ZORBAX Extend C18 column (2.1 × 50 mm, 3.5 μm) was used under gradient elution with acetonitrile and 0.1% formic acid in water as the mobile phase. Validation experiments assessing accuracy, precision, and stability were satisfactory; the lower limit of quantification was 5 ng/mL. For the pharmacokinetic study, three groups of rats were administrated pure DA, pure ND, or NR extract orally. Concentrations of DA and ND in their plasma were determined by the developed method. Pharmacokinetic parameters, including the time to achieve maximum plasma concentration (<I>T</I> <SUB> <I>max</I> </SUB>) and the area under the plasma concentration curve from time zero to infinity (<I>AUC</I> <SUB>0–∞</SUB>), were compared for the herbal extract and pure compounds. The <I>T</I> <SUB> <I>max</I> </SUB> of the pure compound and the NR extract for DA was 7.50 and 8.33 min, respectively, compared to 5.00 and 5.83 min for the pure compound and the NR extract for ND, respectively. The <I>AUC</I> <SUB>0–∞</SUB> of the pure compound and the NR extract for DA was 156.34 and 133.90 μg min/mL, respectively, and that for the NR extract for ND was 6.42 and 4.15 μg min/mL, respectively. LC-MS/MS was used to determine DA and ND in rat plasma. The pharmacokinetic profile of each pure compound and those in the extract were characterized and compared.</P>