http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab
( Pistone Giuseppe ),( Pardo Nicola ),( Caputo Valentina ),( Castelli Elena ),( Curiale Salvatrice ),( Gurreri Rosario ),( Bongiorno Maria Rita ) 대한피부과학회 2018 Annals of Dermatology Vol.30 No.4
Hidradenitis suppurativa (HS) is a disorder of the apocrine gland causing a chronic, recurrent and painful inflammation. It is a disabilitating condition and, though many therapeutic options are available, the response is often ineffective in most cases and patients can present many recurrences with physical and psychological sequelae. Recent data had shown increased interleukin (IL)-17 serum levels in patients with HS. Psoriasis is a chronic immune-mediated inflammatory disorder and new evidences have shown the role of Th17 cells in its pathogenesis and the therapeutic efficacy of anti-IL-17 antibodies. We present a case of a patient suffering from psoriasis and HS successfully treated with anti-IL-17 antibodies for both conditions. This is the first case report of HS treated with secukinumab. (Ann Dermatol 30(4) 462∼464, 2018)
Infrared Scanning Near-Field Optical Microscopy (IR-SNOM) Below the Diffraction Limit
J,S,Sanghera,I,D,Aggarwal,A,Cricenti,R,Generossi,M,Luce,P,Perfetti,G,Margoritondo,N,Tolk,D,Piston 한국세라믹학회 2007 세라미스트 Vol.10 No.3
Infrared Scanning Near-field Optical Microscopy (IR-SNOM) is an extremely powerful analytical instrument since it combines IR spectroscopy’s high chemical specificity with SNOM’s high spatial resolution. In order to do this in the infrared, specialty chalcogenide glass fibers were fabricated and their ends tapered to generate SNOM probes. The fiber tips were installed in a modified near field microscope and both inorganic and biological samples illuminated with the tunable output from a free-electron laser located at Vanderbilt University. Both topographical and IR spectral images were simultaneously recorded with a resolution of ~50 nm and ~100 nm, respectively. Unique spectroscopic features were identified in all samples, with spectral images exhibiting resolutions of up to μ60, or at least 30 times better than the diffraction limited lens-based microscopes. We believe that IR-SNOM can provide a very powerful insight into some of the most important bio-medical research topics.