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Park Bo Eun,Lee Jang Hoon,Park Hyuk Kyoon,Kim Hong Nyun,Jang Se Yong,Bae Myung Hwan,Yang Dong Heon,Park Hun Sik,Cho Yongkeun,Lee Bong Yul,Nam Chang Wook,Lee Jin Bae,Kim Ung,Chae Shung Chull,Daegu COVI 대한의학회 2021 Journal of Korean medical science Vol.36 No.2
Background: Data regarding the association between preexisting cardiovascular risk factors (CVRFs) and cardiovascular diseases (CVDs) and the outcomes of patients requiring hospitalization for coronavirus disease 2019 (COVID-19) are limited. Therefore, the aim of this study was to investigate the impact of preexisting CVRFs or CVDs on the outcomes of patients with COVID-19 hospitalized in a Korean healthcare system. Methods: Patients with COVID-19 admitted to 10 hospitals in Daegu Metropolitan City, Korea, were examined. All sequentially hospitalized patients between February 15, 2020, and April 24, 2020, were enrolled in this study. All patients were confirmed to have COVID-19 based on the positive results on the polymerase chain reaction testing of nasopharyngeal samples. Clinical outcomes during hospitalization, such as requiring intensive care and invasive mechanical ventilation (MV) and death, were evaluated. Moreover, data on baseline comorbidities such as a history of diabetes, hypertension, dyslipidemia, current smoking, heart failure, coronary artery disease, cerebrovascular accidents, and other chronic cardiac diseases were obtained. Results: Of all the patients enrolled, 954 (42.0%) had preexisting CVRFs or CVDs. Among the CVRFs, the most common were hypertension (28.8%) and diabetes mellitus (17.0%). The prevalence rates of preexisting CVRFs or CVDs increased with age (P < 0.001). The number of patients requiring intensive care (P < 0.001) and invasive MV (P < 0.001) increased with age. The in-hospital death rate increased with age (P < 0.001). Patients requiring intensive care (5.3% vs. 1.6%; P < 0.001) and invasive MV (4.3% vs. 1.7%; P < 0.001) were significantly greater in patients with preexisting CVRFs or CVDs. In-hospital mortality (12.9% vs. 3.1%; P < 0.001) was significantly higher in patients with preexisting CVRFs or CVDs. Among the CVRFs, diabetes mellitus and hypertension were associated with increased requirement of intensive care and invasive MV and in-hospital death. Among the known CVDs, coronary artery disease and congestive heart failure were associated with invasive MV and in-hospital death. In multivariate analysis, preexisting CVRFs or CVDs (odds ratio [OR], 1.79; 95% confidence interval [CI], 1.07–3.01; P = 0.027) were independent predictors of in-hospital death after adjusting for confounding variables. Among individual preexisting CVRF or CVD components, diabetes mellitus (OR, 2.43; 95% CI, 1.51–3.90; P < 0.001) and congestive heart failure (OR, 2.43; 95% CI, 1.06–5.87; P = 0.049) were independent predictors of in-hospital death. Conclusion: Based on the findings of this study, the patients with confirmed COVID-19 with preexisting CVRFs or CVDs had worse clinical outcomes. Caution is required in dealing with these patients at triage.
Park, Nyun-Bae,Park, Sang Yong,Kim, Jong-Jin,Choi, Dong Gu,Yun, Bo Yeong,Hong, Jong Chul Elsevier 2017 ENERGY Vol.121 No.-
<P><B>Abstract</B></P> <P>Energy saving potential and carbon dioxide (CO<SUB>2</SUB>) reduction potential of boiler technologies in the Korean industrial sector up to 2035 were analyzed using The Integrated MARKAL-EFOM System (TIMES) model based on bottom-up optimization. Final energy consumption by industrial indirect heating boilers in 2013 accounts for 7% of Korea's industrial energy consumption and 8% of the manufacturing sector's consumption. Energy consumption of industrial indirect heating boilers is expected to increase about 25% in the baseline scenario between 2013 and 2035. Technical potential against the baseline scenario by deploying only the most efficient technologies in new installation demand is 7.9% for energy saving and 20.7% for CO<SUB>2</SUB> reduction by 2035. The most efficient technologies by boiler technology types were gas-fired super boilers. Economic potential against the baseline scenario through market competition between existing and high efficient technologies is 5.6% for energy saving and 6.1% for CO<SUB>2</SUB> reduction by 2035. CO<SUB>2</SUB> reduction potential is higher than energy-saving potential because fuel substitution toward gas was added to the energy-saving effect due to efficiency improvement. Research and development, information disclosure, regulation, and incentives for high-efficiency boiler technologies are necessary to realize technical potential as well as economic potential in industrial indirect heating.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We analyze technical and economic potential of highly efficient boilers in Korea. </LI> <LI> Energy saving potential is 7.9% technically and 5.6% economically by 2035. </LI> <LI> CO<SUB>2</SUB> reduction potential is 20.7% technically and 6.1% economically by 2035. </LI> <LI> Gas-fired super boiler will be the dominant technology in the mid- to long-term. </LI> </UL> </P>
Park Jong Sung,Lee Jang Hoon,Hong Chae Moon,Park Bo Eun,Park Yoon Jung,Kim Hong Nyun,Kim Namkyun,Jang Se Yong,Bae Myung Hwan,Yang Dong Heon,Park Hun Sik,Cho Yongkeun 대한의학회 2023 Journal of Korean medical science Vol.38 No.46
Background: Positron emission tomography (PET) viability scan is used to determine whether patients with a myocardial scar on single-photon emission computed tomography (SPECT) may need revascularization. However, the clinical utility of revascularization decision-making guided by PET viability imaging has not been proven yet. The purpose of this study was to investigate the impact of PET to determine revascularization on clinical outcomes. Methods: Between September 2012 and May 2021, 53 patients (37 males; mean age = 64 ± 11 years) with a myocardial scar on MIBI SPECT who underwent PET viability test were analyzed in this study. The primary outcome was a temporal change in echocardiographic findings. The secondary outcome was all-cause mortality. Results: Viable myocardium was presented by PET imaging in 29 (54.7%) patients. Revascularization was performed in 26 (49.1%) patients, including 18 (34.0%) with percutaneous coronary intervention (PCI) and 8 (15.1%) with coronary artery bypass grafting. There were significant improvements in echocardiographic findings in the revascularization group and the viable myocardium group. All-cause mortality was significantly lower in the revascularization group than in the medical therapy-alone group (19.2% vs. 44.4%, log-rank P = 0.002) irrespective of viable (21.4% vs. 46.7%, log-rank P = 0.025) or non-viable myocardium (16.7% vs. 41.7%, log-rank P = 0.046). All-cause mortality was significantly lower in the PCI group than in the medical therapy-alone group (11.1% vs. 44.4%, log-rank P < 0.001). Conclusion: Revascularization improved left ventricular systolic function and survival of patients with a myocardial scar on SPECT scans, irrespective of myocardial viability on PET scans.
박년배(Nyun-Bae Park),박상용(Sang Yong Park),최동구(Dong Gu Choi),김현구(Hyun-Goo Kim),강용혁(Yong-Heack Kang) 한국태양에너지학회 2016 한국태양에너지학회 논문집 Vol.36 No.1
Geographic information system (GIS) based renewable energy resource map including potential analysis can play a crucial role not only to develop the national plan for renewable energy deployment but also to make strategic investment decision in the private sector. Korea Institute of Energy Research (KIER) has been developing domestic maps about several resources such as solar, wind, hydro, biomass, and geothermal, as well as conducting research on methodologies for potential analysis. Furthermore, the institute is trying to transfer related technologies and know-how to foreign countries, recently. In this context, the main purpose of this study is to introduce the business model of renewable energy resource map. From the value chain analysis, we focus on the government-side market in foreign countries, such as the development of the national level renewable energy resource map and the support of the national renewable energy plan. For about 180 countries, we segment the customers according to the consideration of economic capacity, renewable energy resource capacity, existence of renewable resource map, current portion of renewable energy facility capacity, and renewable energy policies, and we conclude that the target customers are non-Organization for Economic Co-operation and Development (non-OECD) countries or some OECD countries, their per capita GDP are under the average among OECD countries, that do not have renewable resource map yet. We segment the target customers into four groups, and suggest different strategies for market positioning and financing strategy based on Strengths, Weaknesses, Opportunities, Threats (SWOT) analysis. This study can help to develop the business strategy about the development of renewable energy resource map in foreign countries.