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RISS 인기검색어
- 검색키워드
- 저자 : Niu-Jing Ma (검색결과 5 건)
- 무료
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Effects of Impact Loads on Local Dynamic Behavior of Orthotropic Steel Bridge Decks
Niu-Jing Ma,Ronghui Wang 한국강구조학회 2021 International Journal of Steel Structures Vol.21 No.1
To investigate the local dynamic behavior of orthotropic steel bridge decks under impact loads, this paper proposed a type of combined plate-beam element for analysis of trapezoidal stiff ened plate and a type of 8-nodes solid-plate element for analysis of pavement. Besides, vehicle wheel loads are supposed to be triangular loads for convenience. Then, a model experiment was conducted to verify the accuracy of the proposed approach. Finally, River-sea-through channel of Hong Kong–Zhuhai– Macao Bridge is taken as an engineering case for computation analysis. The results are compared with those from FE software ANSYS. It shows that: fi rst, the proposed approach is both accurate and effi cient; second, bridge deck pavement has the eff ect of both self-weight and rigidity, which requires the bridge deck pavement be considered when analyzing the mechanical properties of bridge deck structure.
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Niu-Jing Ma,Li-Xiong Gu,Chang-Li Peng 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.5
To make sure the tension adjustment in the cables of concrete cable-stayed bridges is conducted successfully, a new adjustment technique for the tension adjustment is presented, with the cable-girder temperature difference taken into account. The tensions are measured via frequency method. Prior to the tension adjustment, tensions and temperatures of all cables and girders are measured when the ambient temperature is stable, and this set of tensions is taken as reference tensions. During the tension adjustment, the relative variable quantities of the tensions are regarded as the control values, while the vertical displacement in the mid-span section of the main span is regarded as the verification value. After each pair of cables is adjusted, it is required to measure the temperatures of cables and girders as well as the vertical displacement variation in the mid-span section of the main span. To guarantee the structural behavior of entire bridge is controlled, at one-third cable points, two-third cable points and the farthest cable points, the frequencies of each pair of cables as well as the temperatures of each pair of cables and girders should be measured so as to recalculate the cable tensions. After that, these cable tensions are compared with the theoretical ones to ensure the structural behavior of entire bridge in control. Finally, Furong bridge, a concrete cable-stayed bridge with double inclined pylons, is taken as a sample application of this proposed technique. The results of cable tensions in this bridge illustrate the new adjustment technique is both accurate and efficient.
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Technique for Intrusion Detection based on Cutting-based Real-valued Negative Selection
Niu Ling,Feng Gao Feng,Ma Jing 보안공학연구지원센터 2015 International Journal of Security and Its Applicat Vol.9 No.9
A novel technique for intrusion detection based on cutting-based real-valued negative selection scheme is proposed in this paper. Different from the current typical techniques, the proposed one sets a much more strict and reasonable mechanism to generate and optimize the set of mutual detector. Concretely, firstly, the new generating detector must be necessary and it should not be detected by the current existing mutual ones. Besides, those detectors coinciding with the self-set will be cut and optimized into several qualified ones which have better detecting abilities. Experimental results demonstrate that the proposed technique has much higher detecting rates.
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FNC inhibits non-small cell lung cancer by activating the mitochondrial apoptosis pathway
Jing Xiang,Niu Shuai,Liang Yi,Chen Huiping,Wang Ning,Peng Youmei,Ma Fang,Yue Wanying,Wang Qingduan,Chang Junbiao,Zhang Yi,Zhang Yan 한국유전학회 2022 Genes & Genomics Vol.44 No.1
Background: Previously, we published that 4'-azid-2'-deoxy-2'-fluorarabinoside (FNC), a novel cytosine nucleoside analog, has good anti-viral and anti-tumor activity. Objective: This study aimed to further explore the role and molecular mechanism of FNC in non-small cell lung cancer (NSCLC). Methods: FNC was tested in the NSCLC H460 cell line, the Lewis mouse model, and the H460 cell xenograft model. The effects of FNC were assessed by cell viability, transwell migration, and wound scratch analyses of cell migration and invasion. Apoptosis was assessed by flow cytometry. Proteins expression was assessed by western blot and immunohistochemistry staining (IHC). Results: FNC inhibits the proliferation and metastasis of H460 cells in a time- and dose-dependent manner. FNC treatment showed efficacy and low toxicity in the Lewis mouse lung cancer model as well as in the H460 cell xenograft model. Further, FNC induced H460 cell apoptosis through the activation of the mitochondrial pathway. Notably, FNC inhibited invasion by increasing E-cadherin protein and reducing the protein expression of VEGF, MMP-2, MMP-9, and CD31. Conclusion: FNC inhibits NSCLC by activating the mitochondrial apoptosis pathway and regulating the expressions of multiple proteins related to cell adhesion and invasion, highlighting its potential as an NSCLC therapeutic.
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Nonlinear Vibration of a Stiffened Plate Considering the Existence of Initial Stresses
Tian-Qi Wang,Ronghui Wang,Niu-Jing Ma 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.5
This paper presents a study on the nonlinear dynamic behavior of a stiffened plate with the existence of initial stresses. A stiffened plate is assumed to be composed of a plate and some stiffeners, which are treated separately. The plate is analyzed based on Thin Plate Theory, while the stiffeners are considered as geometrically nonlinear Euler-Bernoulli beams. The equations of both kinetic energies and strain energies of the plate and stiffeners are established. After that, the dynamic equilibrium equations for the stiffened plate are derived according to Lagrange equation. The nonlinear frequency for single-mode result is obtained through Elliptic function, and the accuracy of the analytical solution is verified through comparison with Ansys finite element method. In addition, homotopy analysis method is used to solve 3:1 internal resonance of the stiffened plate. With parametric analysis being conducted, the investigation on how initial stresses influence the nonlinear dynamic properties is carried out. Some useful nonlinear dynamic properties and conclusions are obtained, and thees can provide references for engineering application.
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