The Burden of Stroke in Kurdistan Province, Iran From 2011 to 2017

Moradi, Shahram,Moradi, Ghobad,Piroozi, Bakhtiar The Korean Society for Preventive Medicine 2021 예방의학회지 Vol.54 No.2

Objectives: The aim of this study was to calculate the burden of stroke in Kurdistan Province, Iran between 2011 and 2017. Methods: Incidence data extracted from the hospital information system of Kurdistan Province and death data extracted from the system of registration and classification of causes of death were used in a cross-sectional study. The World Health Organization method was used to calculate disability-adjusted life years (DALYs). Results: The burden of stroke increased from 2453.44 DALYs in 2011 to 5269.68 in 2017, the years of life lost increased from 2381.57 in 2011 to 5109.68 in 2017, and the years of healthy life lost due to disability increased from 71.87 in 2011 to 159.99 in 2017. The DALYs of ischaemic stroke exceeded those of haemorrhagic stroke. The burden of disease, new cases, and deaths doubled during the study period. The age-standardised incidence rate of ischaemic stroke and haemorrhagic stroke in 2017 was 21.72 and 20.72 per 100 000 population, respectively. Conclusions: The burden of stroke is increasing in Kurdistan Province. Since health services in Iran are based on treatment, steps are needed to revise the current treatment services for stroke and to improve the quality of services. Policy-makers and managers of the health system need to plan to reduce the known risk factors for stroke in the community. In addition to preventive interventions, efficient and up-to-date interventions are recommended for the rapid diagnosis and treatment of stroke patients in hospitals. Along with therapeutic interventions, preventive interventions can help reduce the stroke burden.

Enhancement of Soft Soil Behaviour by using Floating Bottom Ash Columns

Razieh Moradi,Aminaton Marto,Ahmad Safuan A Rashid,Mohammad Moeen Moradi,Abideen Adekunle Ganiyu,Mohamad Hafeezi Abdullah,Suksun Horpibulsuk 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.6

The current disposition worldwide is for sustainable construction, and the application of by-products is one of the ways to achieve it. In this research, bottom ash was used as a substitute material in a granular column to decrease settlement and enhance the bearing capacity of soft soil. Bottom ash is a derivate of the coal burning process, it has similar engineering properties to sand and fine gravel. A set of reduced scale physical modelling tests were performed on floating bottom ash columns to assess the improvement in the bearing capacity of the composite ground. The results clearly showed that the bearing capacity of the model soil was greatly improved with the installation of bottom ash column sand. There was an obvious enhancement of the load capacity of the granular columns when they were encased. The usage of bottom ash instead of aggregate or sand for granular columns will reduce the project cost and it aligns with the goal of sustainable construction development.

Geomechanical study of well stability in high-pressure, high-temperature conditions

Moradi, Seyyed Shahab Tabatabaee,Nikolaev, Nikolay I.,Chudinova, Inna V.,Martel, Aleksander S. Techno-Press 2018 Geomechanics & engineering Vol.16 No.3

Worldwide growth in hydrocarbon and energy demand is driving the oil and gas companies to drill more wells in complex situations such as areas with high-pressure, high-temperature conditions. As a result, in recent years the number of wells in these conditions have been increased significantly. Wellbore instability is one of the main issues during the drilling operation especially for directional and horizontal wells. Many researchers have studied the wellbore stability in complex situations and developed mathematical models to mitigate the instability problems before drilling operation. In this work, a fully coupled thermoporoelastic model is developed to study the well stability in high-pressure, high-temperature conditions. The results show that the performance of the model is highly dependent on the truly evaluated rock mechanical properties. It is noted that the rock mechanical properties should be evaluated at elevated pressures and temperatures. However, in many works, this is skipped and the mechanical properties, which are evaluated at room conditions, are entered into the model. Therefore, an accurate stability analysis of high-pressure, high-temperature wells is achieved by measuring the rock mechanical properties at elevated pressures and temperatures, as the difference between the model outputs is significant.

Effects of p53 Codon 72 and MDM2 SNP309 Polymorphisms on Gastric Cancer Risk among the Iranian Population

Moradi, Mohammad-Taher,Salehi, Zivar,Aminian, Keyvan,Yazdanbod, Abbas Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.17

Background: Development of gastric cancer (GC) is a multistep process that requires alterations in the expression of oncogenes and tumor suppressor genes, occurring over several decades. The p53 tumor suppressor protein is involved in cell-cycle control, apoptosis and DNA repair. One of the most important regulators of p53 is MDM2, which acts as a negative regulator in the p53 pathway. Based on the key role of p53 and MDM2 in tumor suppression, polymorphisms that cause change in their function might affect cancer risk. We therefore elevated associations of the polymorphisms of p53 (R72P) and MDM2 (SNP309) with GC in Iran. Materials and Methods: A total of 104 patients with gastric cancer and 100 controls were recruited. Genomic DNA was extracted from fresh gastric samples. Genotyping of the p53 and MDM2 genes was performed using allele specific PCR (AS-PCR). Results: There was no significant difference between the p53 codon 72 polymorphism distribution in control and patient groups (p=0.54), but the G allele of MDM2 was found to be over-represented in patients (p=0. 01, Odds Ratio=2. 08, 95% Confidence Interval= 1.37-4.34). Conclusions: The p53 R72P seems not to be a potential risk factor for development of GC among Iranian patients, but our data suggest that MDM2 SNP309 might modify the risk related to GC.

Prevalence of underweight and wasting in Iranian children aged below 5 years: a systematic review and meta-analysis

Moradi, Yousef,Shadmani, Fatemeh Khosravi,Mansori, Kamyar,Hanis, Shiva Mansouri,Khateri, Rozhin,Mirzaei, Hossein The Korean Pediatric Society 2018 Clinical and Experimental Pediatrics (CEP) Vol.61 No.8

Purpose: Wasting and underweight are the 2 main indicators of children's undernutrition. We aimed to estimate the prevalence of undernutrition at the national level in Iran. Methods: We performed a search for original articles published in international and Iranian databases including MEDLINE, Web of Science, Google Scholar, Scopus, CINHAL (Cumulative Index to Nursing and Allied Health Literature), Scientific Information Database, Irandoc, Iranmedex, and Magiran during January 1989-August 2017. Seven keywords, in English and Persian, including malnutrition, protein energy malnutrition, growth disorders, underweight wasting, weight loss, children below 5 years old, and children, were used to search the databases. Results: Finally, 17 articles were included in the meta-analysis, based on which the prevalence of underweight and wasting in Iranian children were estimated to be 11% and 5%, respectively. The prevalence rates of underweight among children in the central, western, southern, and northern parts of Iran and at the national level were 24%, 5%, 20%, 17%, and 6%, respectively. The prevalence rates of wasting in the central, western, southern, and northern parts of Iran and at the national level were 9%, 4%, 11%, 5%, and 4%, respectively. Conclusion: Although the prevalence of underweight and wasting in Iran was low, some parts of the country showed high prevalence. The main reason behind this difference in the prevalence of malnutrition may be due to the level of development in different regions.

Experimental and numerical investigation of arching effect in sand using modified Mohr Coulomb

Moradi, Golam,Abbasnejad, Alireza Techno-Press 2015 Geomechanics & engineering Vol.8 No.6

In the current paper the results of a numerical simulation that were verified by a well instrumented experimental procedure for studying the arching effect over a trapdoor in sand is presented. To simulate this phenomenon with continuum mechanics, the experimental procedure is modeled in ABAQUS code using stress dependent hardening in elastic state and plastic strain dependent frictional hardening-softening with Mohr Coulomb failure criterion applying user sub-routine. The apparatus comprises rectangular trapdoors with different width that can yield downward while stresses and deformations are recorded simultaneously. As the trapdoor starts to yield, the whole soil mass deforms elastically. However, after an immediate specified displacement, depending on the width of the trapdoor, the soil mass behaves plastically. This behavior of sand occurs due to the flow phenomenon and continues until the stress on trapdoor is minimized. Then the failure process develops in sand and the measured stress on the trapdoor shows an ascending trend. This indicates gradual separation of the yielding mass from the whole soil body. Finally, the flow process leads to establish a stable vault of sand called arching mechanism or progressive collapse of the soil body.

A laboratory and numerical study on the effect of geogrid-box method on bearing capacity of rock-soil slopes

Moradi, Gholam,Abdolmaleki, Arvin,Soltani, Parham,Ahmadvand, Masoud Techno-Press 2018 Geomechanics & engineering Vol.14 No.4

Currently, layered geogrid method (LGM) is the commonly practiced technique for reinforcement of slopes. In this paper the geogrid-box method (GBM) is introduced as a new approach for reinforcement of rock-soil slopes. To achieve the objectives of this study, a laboratory setup was designed and the slopes without reinforcements and reinforced with LGM and GBM were tested under the loading of a circular footing. The effect of vertical spacing between geogrid layers and box thickness on normalized bearing capacity and failure mechanism of slopes was investigated. A series of 3D finite element analysis were also performed using ABAQUS software to supplement the results of the model tests. The results indicated that the load-settlement behavior and the ultimate bearing capacity of footing can be significantly improved by the inclusion of reinforcing geogrid in the soil. It was found that for the slopes reinforced with GBM, the displacement contours are widely distributed in the rock-soil mass underneath the footing in greater width and depth than that in the reinforced slope with LGM, which in turn results in higher bearing capacity. It was also established that by reducing the thickness of geogrid-boxes, the distribution and depth of displacement contours increases and a longer failure surface is developed, which suggests the enhanced bearing capacity of the slope. Based on the studied designs, the ultimate bearing capacity of the GBM-reinforced slope was found to be 11.16% higher than that of the slope reinforced with LGM. The results also indicated that, reinforcement of rock-soil slopes using GBM causes an improvement in the ultimate bearing capacity as high as 24.8 times more than that of the unreinforced slope.

Effect of Castor Oil on Cervical Ripening and Labor Induction: a systematic review and meta-analysis

Moradi, Maryam,Niazi, Azin,Mazloumi, Ehsan,Lopez, Violeta KOREAN PHARMACOPUNCTURE INSTITUTE 2022 Journal of pharmacopuncture Vol.25 No.2

Objectives: Post-term pregnancy is a condition associated with increased maternal and fetal complications. Administration of castor oil causes cervical stimulation by increasing the production of prostaglandins. We examined the effects of castor oil on cervical ripening and labor induction through a systematic review and meta-analysis. Methods: The search process was performed to obtain relevant articles from databases including Pubmed, Cochrane library, Scopus, Science direct, SID, Iran Medex, and Google Scholar using the English keywords of cervical ripening, post-term, castor oil, labor induction, Bishop score, and pregnancy considering all possible combinations without time constraints and their Persian equivalents from national databases. Results: A total of eight related articles from the 19 primary studies were extracted and systematically reviewed. According to a cumulative chart, the difference in the post-intervention Bishop score was statistically significant (standard mean difference [SMD]: 1.64, 95% confidence interval [CI]: 1.67-2.11, p = 0.001), indicating an effect of castor oil on increasing the Bishop score. In addition, the difference in labor induction was statistically significant after the intervention (odds ratio: 11.67, 95% CI: 3.34-40.81, p = 0.001), indicating an effect of castor oil on increasing the odds ratio of labor induction (experience of vaginal delivery). Conclusion: This meta-analysis showed that oral administration of castor oil is effective for cervical ripening and labor induction. Midwives should closely monitor pregnant women with prolonged labor and collaborate with obstetricians to employ castor oil as a safe intervention to induce cervical ripening and labor to prevent undue caesarean surgery.

Socioeconomic Inequalities in the Oral Health of People Aged 15-40 Years in Kurdistan, Iran in 2015: A Cross-sectional Study

Moradi, Ghobad,Moinafshar, Ardavan,Adabi, Hemen,Sharafi, Mona,Mostafavi, Farideh,Bolbanabad, Amjad Mohamadi The Korean Society for Preventive Medicine 2017 Journal of Preventive Medicine and Public Health Vol.50 No.5

Objectives: The aim of this study was to evaluate socioeconomic inequalities in the prevalence of dental caries among an urban population. Methods: This study was conducted among 2000 people 15-40 years of age living in Kurdistan, Iran in 2015. Using a questionnaire, data were collected by 4 trained dental students. The dependent variable was the decayed, missing, and filled teeth (DMF) index. Using principal component analysis, the socioeconomic status (SES) of families was determined based on their household assets. Inequality was measured using the concentration index; in addition, the Oaxaca analytical method was used to determine the contribution of various determinants to the observed inequality. Results: The concentration index for poor scores on the DMF index was -0.32 (95% confidence interval [CI], -0.40 to -0.36); thus, poor DMF indices had a greater concentration in groups with a low SES (p<0.001). Decomposition analysis showed that the mean prevalence of a poor DMF index was 43.7% (95% CI, 40.4 to 46.9%) in the least privileged group and 14.4% (95% CI, 9.5 to 9.2%) in the most privileged group. It was found that 85.8% of the gap observed between these groups was due to differences in sex, parents' education, and the district of residence. A poor DMF index was less prevalent among people with higher SES than among those with lower SES (odds ratio, 0.31; 95% CI, 0.19 to 0.52). Conclusions: An alarming degree of SES inequality in oral health status was found in the studied community. Hence, it is suggested that inequalities in oral health status be reduced via adopting appropriate policies such as the delivery of oral health services to poorer groups and covering such services in insurance programs.

Predictive Factors for Outcomes of Overcorrection Nighttime Bracing in Adolescent Idiopathic Scoliosis: A Systematic Review

Moradi Vahideh,Babaee Taher,Shariat Ardalan,Khosravi Mobina,Saeedi Marjan,Parent-Nichols Jennifer,Cleland Joshua Alan 대한척추외과학회 2022 Asian Spine Journal Vol.16 No.4

Predictive clinical and radiological factors can potentially identify adolescent idiopathic scoliosis (AIS) most likely to benefit from overcorrection nighttime bracing. These factors can provide helpful information in clinical decision making. However, the relationship between these factors and outcomes of overcorrection nighttime bracing is unclear. This systematic review determined the predictive factors for identifying outcomes of overcorrection nighttime bracing in AIS. A systematic search was conducted on PubMed, MEDLINE, Scopus, and Embase from January 1986 to January 2021. Studies on AIS patients, aged 10–18 years, with a Risser sign of 0–2 and an initial Cobb angle of 20°–45°, who were treated with overcorrection nighttime bracing and for whom at least one predictive factor of treatment outcome (failure and/or success) was assessed were included. Two blinded reviewers independently evaluated the studies using a quality assessment tool. To determine predictive factors, the level of evidence was rated through best-evidence synthesis. A total of nine studies met the inclusion criteria. A Providence brace was used in six of the included studies, while a Charleston bending brace was used in three. Findings from two high-quality studies provided strong evidence of the association between curve flexibility and brace treatment success. In terms of the Risser sign, this evidence was obtained from three high-quality studies. Moderate evidence indicated a positive association between premenarchal status and nighttime bracing failure. Inconclusive evidence indicated that poor brace compliance is associated with treatment failure. Conflicting evidence of treatment failure was indicated for initial curve magnitude, curve type, in-brace correction, age, Risser sign, curve apex, and sex. These findings show that greater curve flexibility and a higher Risser sign are associated with overcorrection nighttime bracing success.