http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Lee, Ji Yeong,Seong, Won Kyung,Joe, Minwoong,Lee, Kwang‐,Ryeol,Park, Jong‐,Ku,Moon, Myoung‐,Woon,Yang, Cheol‐,Woong John Wiley Sons, Ltd 2012 Surface and interface analysis Vol.44 No.11
<P>We report a phenomenological study of Cu(In,Ga)Se<SUB>2</SUB> (CIGS) dots and their morphological transition into nano‐ridge shapes induced by application of a focused ion beam (IB) to CIGS film. Real‐time observations of nano‐structure evolution during IB irradiation were obtained by recording sequential images at various ion energies of 1 to 30 keV. We observed that as irradiation time increased, the dots became larger and developed elongated ridge structures under continuous sputtering. This transition process was induced by a combination of the Ostwald ripening processes and cluster diffusion. Compositional analysis revealed that the nano‐dots changed from pristine CIGS to Cu‐rich CIGS. The Ga content of the dots was also found to increase due to sputtered implantation, while levels of In and Se decreased. Copyright © 2012 John Wiley & Sons, Ltd.</P>
Yim, Jong Hyuk,Joe, Sung-yoon,Pang, Christina,Lee, Kyung Moon,Jeong, Huiseong,Park, Ji-Yong,Ahn, Yeong Hwan,de Mello, John C.,Lee, Soonil American Chemical Society 2014 ACS NANO Vol.8 No.3
<P>We report the fabrication of efficient indium–tin–oxide-free organic solar cells based on poly(3-hexylthiophene-2,5-diyl):[6,6]-phenyl-C61-butyric acid methyl ester (P3HT:PCBM). All layers of the devices from the lowermost silver nanowire cathode to the uppermost conducting polymer anode are deposited from solution and processed at plastic-compatible temperatures <200 °C. Owing to the absence of an opaque metal electrode, the devices are semitransparent with potential applications in power-generating windows and tandem-cells. The measured power conversion efficiencies (PCEs) of 2.3 and 2.0% under cathode- and anode-side illumination, respectively, match previously reported PCE values for equivalent semitransparent organic solar cells using indium tin oxide.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2014/ancac3.2014.8.issue-3/nn406672n/production/images/medium/nn-2013-06672n_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn406672n'>ACS Electronic Supporting Info</A></P>
박현승 ( Hyun-sung Park ),유지수 ( Ji-su Yu ),조동기 ( Dong-ki Joe ),김민우 ( Min-woo Kim ),문남미 ( Nammee Moon ) 한국정보처리학회 2014 한국정보처리학회 학술대회논문집 Vol.21 No.2
모바일 헬스케어의 기본 개념은 ‘치료’가 아닌 ‘관리’에 있다. 심박수 측정으로 내가 가진 운동 능력을 얼마나 사용하고 있는지 또는 얼마나 사용할 것인지 조절할 수 있고 자신에게 필요한 운동을 맞춤형식으로 조절이 가능하다. 선행연구에서 다뤘던 심박수 구간별 3대 영양소 연소 비율을 통해 다이어트를 목적으로 운동을 조절할 수도 있고 근력 강화를 위해 전문 트레이닝을 강행 할 수도 있다. 본 연구에서는 건강관리를 위한 생체신호 측정 센서 기반 스마트 기기로 심장수을 믈루투스를 사용하여 측정 하고 이상을 예측·보고할 수 있는 프로토타입을 개발하고, 정성적, 정략정 평가를 실시하였다. 향후, 사용성 평가 결가를 기반으로 도출된 문제점의 수정·보완을 통해 최종 센서기반 스마트 심장박동 관리기를 구성하고자 한다.
PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death
Choi, Hyo-Kyoung,Choi, Youngsok,Kang, HeeBum,Lim, Eun-jin,Park, Soo-Yeon,Lee, Hyun-Seob,Park, Ji-Min,Moon, Jisook,Kim, Yoon-Jung,Choi, Insup,Joe, Eun-Hye,Choi, Kyung-Chul,Yoon, Ho-Geun IRL Press 2015 Human molecular genetics Vol.24 No.4
<P>Deciphering the molecular basis of neuronal cell death is a central issue in the etiology of neurodegenerative diseases, such as Parkinson's and Alzheimer's. Dysregulation of p53 levels has been implicated in neuronal apoptosis. The role of histone deacetylase 3 (HDAC3) in suppressing p53-dependent apoptosis has been recently emphasized; however, the molecular basis of modulation of p53 function by HDAC3 remains unclear. Here we show that PTEN-induced putative kinase 1 (<I>PINK1</I>), which is linked to autosomal recessive early-onset familial Parkinson's disease, phosphorylates HDAC3 at Ser-424 to enhance its HDAC activity in a neural cell-specific manner. PINK1 prevents H<SUB>2</SUB>O<SUB>2</SUB>-induced C-terminal cleavage of HDAC3 via phosphorylation of HDAC3 at Ser-424, which is reversed by protein phosphatase 4c. PINK1-mediated phosphorylation of HDAC3 enhances its direct association with p53 and causes subsequent hypoacetylation of p53. Genetic deletion of PINK1 partly impaired the suppressive role of HDAC3 in regulating p53 acetylation and transcriptional activity. However, depletion of HDAC3 fully abolished the PINK1-mediated p53 inhibitory loop. Finally, ectopic expression of phosphomometic-HDAC3<SUP>S424E</SUP> substantially overcomes the defective action of PINK1 against oxidative stress in dopaminergic neuronal cells. Together, our results uncovered a mechanism by which PINK1–HDAC3 network mediates p53 inhibitory loop in response to oxidative stress-induced damage.</P>