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- 검색키워드
- 저자 : Ming-xing Chu (검색결과 3 건)
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Construction of antibacterial layer on polyvinylchloride three-channel hollow fiber membranes
Mei-Sheng Li,Ming-Xing Wang,Fei-Yue Wu,Xiao-Zhong Chu 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.39 No.-
The inner surfaces of polyvinylchloride (PVC) three-channel hollow fiber membranes were successfullymodified with poly(methacryloxylethyl benzyl dimethyl ammonium chloride) (PDMAE-BC) in a modulescale via remote plasma-induced surface graft polymerization method. After grafting a PDMAE-BC layer,the PVC surface hydrophilicity was improved greatly due to the introduction of large amounts of oxygenand nitrogen containing polar groups onto polymer backbone. This hydrophilicity improvement directlyleaded to a high pure water flux and a good antifouling property for the obtained PVC-PDMAE-BCmembrane module. Meanwhile, the inner surface morphologies of modified PVC membranes changedslightly and the surface structures were maintained well. The tensile strength, though deceased slightlyat the remote plasma-treated stage, showed no significant change during overall grafting process. Theobtained PVC-PDMAE-BC membrane module exhibited highly effective and stable antibacterialactivities against Escherichia coli. The antibacterial efficacy of PVC-PDMAE-BC membrane module withonly 6 fibers can achieve about 96.3% and could be further enhanced by increasing the packing density. The antibacterial membrane module may have great potential applications in actual wastewatertreatment and membrane bioreactor (MBR).
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Jin, Mei,Zhang, Jun-yan,Chu, Ming-xing,Piao, Jun,Piao, Jing-ai,Zhao, Feng-qin Asian Australasian Association of Animal Productio 2018 Animal Bioscience Vol.31 No.5
Objective: The study investigated the biological functions and mechanisms for controlling cashmere growth of Liaoning cashmere goat by ovarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) and decorin (DCN) genes. Methods: cDNA library of Liaoning cashmere goat was constructed in early stages. OCIAD2 and DCN genes related to cashmere growth were identified by homology analysis comparison. The expression location of OCIAD2 and DCN genes in primary and secondary hair follicles (SF) was performed using in situ hybridization. The expression of OCIAD2 and DCN genes in primary and SF was performed using real-time polymerase chain reaction (PCR). Results: In situ hybridization revealed that OCIAD2 and DCN were expressed in the inner root sheath of Liaoning cashmere goat hair follicles. Real-time quantitative PCR showed that these genes were highly expressed in SF during anagen, while these genes were highly expressed in primary hair follicle in catagen phase. Melatonin (MT) inhibited the expression of OCIAD2 and promoted the expression of DCN. Insulin-like growth factors-1 (IGF-1) inhibited the expression of OCIAD2 and DCN, while fibroblast growth factors 5 (FGF5) promoted the expression of these genes. MT and IGF-1 promoted OCIAD2 synergistically, while MT and FGF5 inhibited the genes simultaneously. MT+IGF-1/MT+FGF5 inhibited DCN gene. RNAi technology showed that OCIAD2 expression was promoted, while that of DCN was inhibited. Conclusion: Activation of bone morphogenetic protein (BMP) signaling pathway up-regulated OCIAD2 expression and stimulated SF to control cell proliferation. DCN gene affected hair follicle morphogenesis and periodic changes by promoting transforming growth $factor-{\beta}$ ($TGF-{\beta}$) and BMP signaling pathways. OCIAD2 and DCN genes have opposite effects on $TGF-{\beta}$ signaling pathway and inhibit each other to affect the hair growth.
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Luzhong mutton sheep: inbreeding and selection signatures
Lin Tao,Xiaoyun He,Fengyan Wang,Yingjie Zhong,Linxiang Pan,Xiangyu Wang,Shangquan Gan,Ran Di,Ming-xing Chu 한국축산학회 2020 한국축산학회지 Vol.62 No.6
Intense artificial selection has been imposed to Luzhong mutton sheep population in the past years. Improvements on growth and reproductive performance are two breeding goals in the present herd. Although some progresses were phenotypically observed possibly due to inbreeding induced by strong selection in terms of these traits, the genomic evaluation was poorly understood. Therefore, a high-density SNP array was used to characterize the pattern of runs of homozygosity (ROH), estimate inbreeding and inbreeding depressions on early growth performance and litter size based upon ROH, and scan positive selection signatures of recent population. Consequently, a low inbreeding level was observed which had negative effects on litter size, but not on early growth performance. And 160 genes were under selection, of which some were reported to be linked to several traits of sheep including body weight, litter size, carcass and meat quality, milk yield and composition, fiber quality and health, and the top genes were associated with growth (growth hormone [GH]- growth hormone receptor [GHR]- Insulin-like growth factor 1 [IGF1] axis) and litter size (bone morphogenic proteins [BMPs]-associated). The effectiveness of previous breeding measures was highlighted, but purging selection was proposed to alleviate the inbreeding depression on litter size, providing some genomic insights to breeding management of Luzhong mutton sheep.
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