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        Tissue engineering in plastic and reconstructive surgery: fostering advances in the 21st century via an understanding of the present state of the art and future possibilities

        Manish Anand,Manish Bhagania,Kiranmeet Kaur 대한미용성형외과학회 2023 Archives of Aesthetic Plastic Surgery Vol.29 No.2

        Tissue engineering is a subfield of regenerative medicine that has been hailed as the most cutting-edge medical and surgical achievement to date. Tissue engineering aims to restore or construct whole tissues that have been lost due to congenital disabilities, trauma, or surgery. Tissue engineering is based on the premise of obtaining mesenchymal stem cells that can be used to create an embryologically comparable organ. To regenerate an organ that resembles the intended tissue to be replaced, a complex synergistic interplay between stem cells, signaling molecules, and scaffold, is required. Tissue engineering in plastic surgery is expected to reduce surgical morbidity by integrating cell signals or bio-artificial components taken from the patient’s cells, which may replace damaged bodily tissue without the need for extensive reconstructive surgery. With the advent of 3-dimensional printers for modeling scaffolds and current tissue engineering methods for the regeneration of muscle, bone, and cartilage in the laboratory, the scope of tissue engineering is no longer confined to cells and scaffolds, but also encompasses growth factors and cytokines. Although these methods seem promising, clinical success has been limited to essential tissue regeneration, with considerable difficulties remaining to overcome. This paper aims to introduce readers to tissue engineering’s existing breadth, regeneration processes, limits, and prospects.

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      • KCI등재

        Structural and Optical Properties of Co- and Ti-ZnO Composite Nanofibers Prepared by Using an Electrospinning Method

        김원배,Manish Anand,심희상,김용석,김해진 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.53 No.5

        We report here a simple preparation method that involves a room-temperature sol-gel process to prepare Co- and Ti-composited ZnO nanofibers via electrospinning. By choosing a combination of two solvents for the low-temperature sol-gel process and proper using the process parameters, we could get improved morphology and reduced diameters of the doped and the undoped ZnO nanofibers. The morphology of the undoped, as well as the doped, ZnO nanobers was porous with diameters in the range of 40 to 100 nm. The undoped ZnO nanofibers were found to be crystalline and their crystallinity appeared to be unaffected, even by doping with Ti and Co up to 3 atomic%. The band gap values of pure ZnO and doped ZnO nanofibers with Ti (3 atomic%) and Co (3 atomic%) were estimated by to be 3.29, 3.30 and 3.02 eV, respectively, using UV-vis absorption spectra. We report here a simple preparation method that involves a room-temperature sol-gel process to prepare Co- and Ti-composited ZnO nanofibers via electrospinning. By choosing a combination of two solvents for the low-temperature sol-gel process and proper using the process parameters, we could get improved morphology and reduced diameters of the doped and the undoped ZnO nanofibers. The morphology of the undoped, as well as the doped, ZnO nanobers was porous with diameters in the range of 40 to 100 nm. The undoped ZnO nanofibers were found to be crystalline and their crystallinity appeared to be unaffected, even by doping with Ti and Co up to 3 atomic%. The band gap values of pure ZnO and doped ZnO nanofibers with Ti (3 atomic%) and Co (3 atomic%) were estimated by to be 3.29, 3.30 and 3.02 eV, respectively, using UV-vis absorption spectra.

      • SCISCIESCOPUS

        Polymorphic transformations and optical properties of graphene-based Ag-doped titania nanostructures

        Mathpal, Mohan Chandra,Tripathi, Anand Kumar,Kumar, Promod,R., Balasubramaniyan,Singh, Manish Kumar,Chung, Jin Suk,Hur, Seung Hyun,Agarwal, Arvind The Royal Society of Chemistry 2014 Physical chemistry chemical physics Vol.16 No.43

        <P>TiO<SUB>2</SUB> is the most studied semiconductor material for photovoltaics and photocatalyst applications, but due to a very large electron hole recombination process it is difficult to use it as a photovoltaics material. In this context graphene-decorated Ag-doped TiO<SUB>2</SUB> nanostructures have been synthesized by a simple, cost effective chemical method. In this paper, we have studied the structural transformations and electronic band structure of Ag-doped TiO<SUB>2</SUB> due to the incorporation of graphene oxide. Pure rutile and anatase–rutile mixed phases of TiO<SUB>2</SUB> nanoparticles were obtained by Ag doping and annealing at 400 °C. A large red shift was observed in most of the graphene-decorated, doped TiO<SUB>2</SUB> hybrid nanostructures, which is because of the electron transfer between the conduction bands of the doped TiO<SUB>2</SUB> and the multilayer graphene. The Ag-doped TiO<SUB>2</SUB> nanoparticles appear in the shape of a bunch of bananas (or rice-like) because of the jumbled collection of particles, which remain unaltered even after graphene decoration. The strong electrical coupling of Ag-doped TiO<SUB>2</SUB> with reduced graphene oxide produces an advanced hybrid material useful for superior photovoltaics, photocatalytic activity and other applications.</P> <P>Graphic Abstract</P><P>Electron transfer phenomenon occurs between doped TiO<SUB>2</SUB> and multilayer graphene. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c4cp02982h'> </P>

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