Postoperative survival According to the Glasgow Prognostic Score in Patients with Resected Lung Adenocarcinoma

Machida, Yuichiro,Sagawa, Motoyasu,Tanaka, Makoto,Motono, Nozomu,Matsui, Takuma,Usuda, Katsuo,Uramoto, Hidetaka Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.10

Background: The Glasgow Prognostic Score (GPS) is calculated from measured CRP and albumin levels. We here evaluated the significance of the GPS in patients with resected pulmonary adenocarcinoma. Materials and Methods: The present study included 156 patients with lung adenocarcinoma who underwent lobectomy at Kanazawa Medical University between 2002 and 2012. Classification was into three groups: those with normal albumin (>=3.5 g/dl) and C-reactive protein (CRP) (<=1.0 mg/dl) levels were classified as GPS 0 (n =136), those with low albumin (<3.5 g/dl) or elevated CRP (>1.0 mg/dl) levels as GPS 1 (n = 16), and those with low albumin (<3.5 g/dl) and elevated CRP (>1.0 mg/dl) levels as GPS 2 (n = 4). We retrospectively investigated relationships between the patient characteristics including the GPS, and disease-free survival and cancer-specific survival. Results: The pathological stages of the patients were as follows: IA (n=78, 50%), IB (n=31, 19.9%), IIA (n=20.0, 12.8%), IIB (n=9.0, 5.7%), and IIIA (n=18.0, 11.5%). Lobectomy was performed in all cases. The average GPS was 0.15 (0-2) and showed significant relationships with stage and tumor size. The 2-year survival rates in patients with GPS0, 1 and 2 were 81.4%, 38.4%, and 25.0%, respectively. Clear correlations were noted with both cancer-specific survival and disease-free survival. Furthermore, multivariate analysis revealed that GPS was a significant prognostic factor. Conclusions: The GPS could be a prognostic factor for patients with resected pulmonary adenocarcinoma.

Colossal Seebeck Coefficient of Hopping Electrons in_(TMTSF)2_PF6

Machida, Yo,Lin, Xiao,Kang, Woun,Izawa, Koichi,Behnia, Kamran American Physical Society 2016 Physical review letters Vol.116 No.8

CLINICAL EVALUATION OF NEW RENAL IMAGING AGENT Tc-99m DMP

Machida, Toyohei,Higashi, Yoichiro 대한핵의학회 1984 핵의학 분자영상 Vol.18 No.1

Neoadjuvant chemotherapy for epithelial ovarian cancer in Japan: a JSGO-JSOG joint study

Hiroko Machida,Koji Matsuo,Takayuki Enomoto,Mikio Mikami 대한부인종양학회 2019 Journal of Gynecologic Oncology Vol.30 No.6

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海洋都市下関と朝鮮半島-朝鮮通信使を中心として-

町田一仁(Machida Kazuto) 부경대학교 인문사회과학연구소 2019 인문사회과학연구 Vol.20 No.3

下関は日本の本州の最西端に位置する海陸交通の要衝で、日本国内はもとより、朝鮮半島(韓半島)や中国とも有史以来、密接なつながりを持ち、海洋都市として発展した。特に朝鮮半島とは一衣帯水の地であり、人、モノ、情報が海の道を介して活発に行き交って、前近代では朝鮮半島の文化を強く受容し、近代以降は日本の朝鮮半島侵略の拠点となった。 本稿は、海洋都市下関と朝鮮半島の関係について時代別に概観するとともに、当地における朝鮮通信使御馳走および朝鮮漂流民送還の様相について紹介するものである。 朝鮮通信使にとって下関は、使行の安全を確保する重要な地であった。そのため、対馬易地聘礼となった1811年を除く全ての朝鮮通信使が目的地への往復の途次に必ず寄港している。この地での朝鮮通信使御馳走は長州藩毛利氏の役割であり、毛利氏は各使行とも懇切丁寧に応接し、1711年の使行では｢長門下之関御馳走一番｣と評価された。また、下関の客館であった阿弥陀寺において、長州藩の学者は通信使と積極的に学術交流を行って、藩内の学問興隆に貢献した。朝鮮通信使も下関の地理的･軍事的拠点性に着目しており、詳細な観察を行って使行録に記録している。 朝鮮通信使の往来によりもたらされた両国の平和的な外交関係は、朝鮮漂流民の救助と送還体制を確固たるものとした。近世下関には44回376人の朝鮮人が漂着しているが、全ての漂流民がこの地の人々に救助･保護されて、無事朝鮮国に送還されている。 Shimonoseki is placed in the westernmost of Japan Honshu, and it is the stronghold place of the amphibious trade. Therefore Shimonoseki is the representative marine city which has been interchanged many regions with inside and outside of Japan, such as Korea and China since the dawn of history. Especially Shimonoseki is separated from Korean peninsula by a narrow strip of water, the people and things and information of two regions exchanged frequently by the sea route. Shimonoseki accepted the culture of the Korean peninsula strongly, but it was changed to the base of invasion by Japan from modern-age. Here, I would give a conspectus of the relations of between marine city Shimonoseki and the Korean peninsula in order of the times, besides introduce about the Chosen Chusinsi receptions and the deportations of Korean drifters in Shimonoseki. Shimonoseki was the very important place for security of the Chosen Chusinsi mission. Therefore all Chosen Chusinsi mission expect 1811 year was visited at Shimonoseki by all means. The receptions of Shimonoseki was taken charged by Moori Lord of Chou Shu feud, Moori Lord went to meet Chosen Chusinsi mission on arrival with all his heart every times. Especially the Chosen Chusinsi mission of Shimonoseki in 1711 year was estimated as the best reception such as Nagato Shimonoseki Gochisou Ichiban. Besides many scholars of Chou Shu interchanged academic exchange with the Chosen Chusinsi mission actively in Amita Temple, and it made a great contributions to cultural development of Chou Shu region. The Chosen Chusinsi mission were concerned about of the geographical and militarily important position, watched and wrote in detail in their journals. The exchange of Chosen Chusinsi made the peaceful diplomatic relations between Japan and Korea, and the rescue and the deportations of Korean drifters from Japan to Korea were settled in pre-modern ages. 376 Korean persons were drifted to Shimonoseki ashore by 44 times in pre-modern ages. All drifting Korean persons were rescued and protected by the people of Shimonoseki, and they were sented to Korea safely.

Who Supports Nuclear Armament in Japan? Threat Perceptions and Japan's Nuclear Armament

Satoshi Machida 서울대학교행정대학원 2014 Asian Journal of Political Science Vol.22 No.2

The security environment in East Asia has been going through drastic changes. As China and North Korea pose a serious threat to Japan, the Japanese are now more concerned about the security issue in the region. Recognizing the highly volatile situation Japan is facing, the purpose of this study is to examine the issue of nuclear proliferation by focusing on people's attitudes in Japan. More specifically, it systematically analyzes the factors that can determine people's opinions of nuclear weapons by utilizing the survey data. The result of the statistical analysis suggests that threat perceptions significantly boost people's support for nuclear armament. Advancing our understanding of nuclear proliferation from a unique perspective, this study makes an important contribution to the literature, thus helping us predict Japan's security policy.

Studying Career Advancement of Women Coaches

Moe Machida,Deborah L. Feltz 한국코칭능력개발원 2013 International Journal of Coaching Science Vol.7 No.2

The representation of women coaches in athletics is still limited. Taking psychosocial perspectives, many researchers have studied “why” women are not gaining access to the higher coaching positions in athletics and have explored “how” to improve women’s status in coaching careers. Informed by social-cognitive theory, research literature, and leadership models, we present a model of women’s career advancement in coaching, which proposes leader self-efficacy as a focal career facilitating factor. We reviewed research on the effects of gender discrimination, extensive domestic responsibility, resiliency, and developmental experiences on women’s leader self-efficacy and career advancement. Methodological considerations for future research on this topic are also discussed.

Significance of histology and nodal status on the survival of women with early-stage cervical cancer: validation of the 2018 FIGO cervical cancer staging system

Hiroko Machida,Koji Matsuo,Yoichi Kobayashi,Mai Momomura,Fumiaki Takahashi,Tsutomu Tabata,Eiji Kondo,Wataru Yamagami,Yasuhiko Ebina,Masanori Kaneuchi,Satoru Nagase,Mikio Mikami 대한부인종양학회 2022 Journal of Gynecologic Oncology Vol.33 No.3

Objective: To assess the efficacy of the FIGO 2018 classification system for nodal-specific classifications for early-stage cervical cancer; specifically, to examine the impact of nodal metastasis on survival and the effect of postoperative treatments, according to histological subtypes. Methods: This society-based retrospective observational study in Japan examined 16,539 women with the 2009 FIGO stage IB1 cervical cancer who underwent primary surgical treatment from 2004 to 2015. Associations of cause-specific survival (CSS) with nodal metastasis and postoperative adjuvant therapy were examined according to histology type (squamous cell carcinoma [SCC], n=10,315; and non-SCC, n=6,224). Results: The nodal metastasis rate for SCC was higher than that for non-SCC (10.7% vs. 8.3%, p<0.001). In multivariable analysis, the impact of nodal metastasis on CSS was greater for non-SCC tumors (adjusted-hazard ratio [HR], 3.11; 95% confidence interval [CI], 2.40– 4.02) than for SCC tumors (adjusted-HR, 2.20; 95% CI, 1.70–2.84; p<0.001). Propensity score matching analysis showed significantly lower CSS rates for women with pelvic nodal metastasis from non-SCC tumors than from SCC tumors (5-year CSS rate, 75.4% vs. 90.3%, p<0.001).The CSS rates for women with nodal metastasis in SCC histology were similar between the postoperative concurrent chemoradiotherapy/radiotherapy and chemotherapy groups (89.2% vs. 86.1%, p=0.42), whereas those in non-SCC histology who received postoperative chemotherapy improved the CSS (74.1% vs. 67.7%, p=0.043). Conclusion: The node-specific staging system in the 2018 FIGO cervical cancer classification is applicable to both non-SCC tumors and SCC tumors; however, the prognostic significance of nodal metastases and efficacy of postoperative therapies vary according to histology.

Excipients in Development of Topical Drug Delivery Systems

(Yoshiharu Machida) 한국약제학회 1993 PROCEEDINGS OF THE FIP POST-SATELLITE SYMPOSIUM `9 Vol.- No.-

NMR Study of Orientational Order in the 7OCB Nematic Liquid Crystal

Mitsuo Machida,T Kakiuchi 한국물리학회 2007 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.51 No.2I

Orientational ordering of 7OCB (4-heptyloxyl-4'-cyanobipheny) in the nematic phase was studied by analyzing the chemical shift of the 13C NMR spectra. The spectra calculated for aromatic carbons reproduce well the observed ones. The obtained orientational order-parameters are 0.444 at 343 K and 0.595 at 315 K.g