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      • Business-Driven Process Fragment Selections in RESTful Business Processes

        Qinghua Lu,Xiwei Xu,Weishan Zhang,Liming Zhu,Shanshan Li 보안공학연구지원센터(IJUNESST) 2015 International Journal of u- and e- Service, Scienc Vol.8 No.1

        Past work showed that runtime adaptability of business processes can be improved by applying Representational State Transfer (REST) to design and implementation of business processes. However, the existing solutions for RESTful business processes (RESTfulBP) were focused on manual selection of process fragments to be composed at runtime. In this paper, we propose solutions that enable semi-automatic selection of process fragment at each decision-making point of RESTfulBP. The new built-in middleware MiniZnMASC can provide user based process fragment advice to knowledge workers in ways that achieve better overall business value while satisfying all existing constraints. In addition, we redesign the architecture of RESTfulBP in order to allow the business-driven decision-making solutions. The solutions are evaluated for feasibility, functional correctness, business benefits, and performance.

      • KCI등재

        Acupuncture-related therapies for protracted opioid abstinence syndrome: A systematic review and meta-analysis

        Ding Lu,Cui Li,Zhang Peiming,Chen Chen,Zhan Jie,Zeng Jinchun,Lu Liming 한국한의학연구원 2023 Integrative Medicine Research Vol.12 No.3

        Background: An increasing amount of clinical evidence of acupuncture's effect on protracted opioid abstinence syndrome (POAS) has emerged in recent years. The aim of this study was to evaluating the evidence of efficacy of acupuncture for POAS. clinical and scientific research work. Methods: Four English-language databases (PubMed, Medline, Embase, Cochrane Libraries) and three Chinese-language databases (CNKI, WanFang and VIP Libraries) were searched, with coverage from database inception to March 31, 2022. Randomized clinical trials (RCTs) evaluating the effects of acupuncture and acupuncture-related therapies for prophylaxis or treatment of POAS were included. Data were screened and extracted independently according to pre-set tabular formats. RCT quality was assessed using risk of bias tool in the Cochrane Collaboration. The primary outcome was opiate withdrawal scale. The secondary outcomes are depression, anxiety for assessing protracted symptoms. The scores on the above scales are proportional to the severity of the symptoms. Results: Twenty-eight trials met the inclusion criteria and provided data for the meta-analysis. A total of only 3 studies (11%) were judged to be low-risk overall due to various biases in them. Acupuncture-related therapy showed statistical differences in improving protracted withdrawal symptom scores compared with sham acupuncture (5 studies, Standard mean difference (SMD), -1.85, 95% CI [-3.21, -0.50], P = 0.007), western medicine(7 studies, SMD, -0.72, 95% CI [-1.22, -0.21], P = 0.005)and no treatment(3 studies, SMD,-2.26, 95% CI [-3.82, -0.69], P = 0.005)with high heterogeneity. Conclusions: Acupuncture maybe safe and effective in relieving POAS individuals’ protracted withdrawal symptoms. However, the results of our review should be interpreted with caution because of the high risk of bias of the included trials.

      • KCI등재

        Aircraft Recognition from Remote Sensing Images Based on Machine Vision

        Lu Chen,Liming Zhou,Jinming Liu 한국정보처리학회 2020 Journal of information processing systems Vol.16 No.4

        Due to the poor evaluation indexes such as detection accuracy and recall rate when Yolov3 network detects aircraft in remote sensing images, in this paper, we propose a remote sensing image aircraft detection method based on machine vision. In order to improve the target detection effect, the Inception module was introducedinto the Yolov3 network structure, and then the data set was cluster analyzed using the kmeans algorithm. In order to obtain the best aircraft detection model, on the basis of our proposed method, we adjusted the network parameters in the pretraining model and improved the resolution of the input image. Finally, our methodadopted multiscale training model. In this paper, we used remote sensing aircraft dataset of RSODDataset to do experiments, and finally proved that our method improved some evaluation indicators. The experiment of this paper proves that our method also has good detection and recognition ability in other ground objects.

      • KCI등재

        Depression and Structural Factors Are Associated With Symptoms in Patients of Irritable Bowel Syndrome With Diarrhea

        ( Jia Lu ),( Lili Shi ),( Dan Huang ),( Wenjuan Fan ),( Xiaoqing Li ),( Liming Zhu ),( Jing Wei ),( Xiucai Fang ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2020 Journal of Neurogastroenterology and Motility (JNM Vol.26 No.4

        Background/Aims A strong correlation between depression and irritable bowel syndrome with diarrhea (IBS-D) has been identified. The aim of this study is to identify the correlations among depression, structural factors, gastrointestinal (GI) and extra-GI symptoms, and efficacy of neuromodulators in patients with IBS-D. Methods Patients meeting the Rome III Diagnostic Criteria for IBS-D were enrolled. The intestinal symptoms and psychological states were evaluated using IBS-specific symptom questionnaires and Hamilton Depression Rating Scale. Results In total, 410 patients with IBS-D were enrolled, 28.8% (118/410) had comorbid depression. Patients with depression did not readily experience improvement in abdominal pain/discomfort after defecation, and had a higher prevalence of passing mucus, overlapping functional dyspepsia, and extra-GI symptoms. The structural factor “mental disorders” significantly correlated with main bowel symptom score and degree of pre-defecation abdominal pain/discomfort. No structural factor significantly correlated with bowel movements or stool form. Patients who had passing mucus, overlapping functional dyspepsia and extra-GI painful symptoms have higher score of “anxiety/somatization.” Patients with sexual dysfunction have higher score of “retardation symptoms.” In total, 28.3% of patients with IBS-D were prescribed neuromodulators. Baseline scores of “anxiety/somatization” and “retardation symptoms” positively correlated with improvement of diarrhea after paroxetine, and “sleep disturbances” positively correlated with improvement of abdominal pain/discomfort and diarrhea after mirtazapine. Conclusions Comorbid depression and higher scores of structural factors might aggravate GI and extra-GI symptoms other than bowel movements and stool form. Structural factors of Hamilton Depression Rating Scale correlated with efficacy of paroxetine and mirtazapine in patients with IBS-D. (J Neurogastroenterol Motil 2020;26:505-513)

      • Error Analysis of Multidimensional Evaluation of Pilot’s Workload Based on Objective Measures

        Chan Wei,Liming Wei,Zhengxiang Cai,Yanyu Lu,Qi Wu,Dan Huang,Shan Fu 제어로봇시스템학회 2015 제어로봇시스템학회 국제학술대회 논문집 Vol.2015 No.10

        Evaluation of pilot’s workload during flight is a significant consideration for the safety of civil aviation. However, some errors may be brought in the measurement and the recording of objective parameters. Based on a multidimensional workload evaluation, the time delay of cardiac activity and its impacts on workload are analyzed. The results suggest that within a certain limit of error around 10s, varying from individual to individual, workload can keep the main information compared to the original workload. As the error increases, the workload may become unreliable. As a consequence, the time-delay error of cardiac activity should be controlled in a limited scale to ensure the validity and reliability of workload.

      • KCI등재

        Effect of D-(+)-Glucose on the Stability of Polyvinyl Alcohol Fricke Hydrogel Three-Dimensional Dosimeter for Radiotherapy

        Yuejiao Yang,Jie Chen,Liming Yang,Bin Chen,Zhenmei Sheng,Wenyun Luo,Guoping Sui,Xun Lu,Jianxin Chen 한국원자력학회 2016 Nuclear Engineering and Technology Vol.48 No.3

        D-(+)-glucose (Glc) was added to the original Fricke polyvinyl alcoholeglutaraldehydeexylenol orange (FPGX) hydrogel dosimeter system to make a more stable FPGX hydrogelthree-dimensional dosimeter in this paper. Polyvinyl alcohol was used as a substrate,which was combined with Fricke solution. Various concentrations of Glc were tested withlinear relevant fitting for optimal hydrogel production conditions. The effects of variousformulations on the stability and sensitivity of dosimeters were evaluated. The resultsindicated that D-(+)-Glc, as a free radical scavenger, had a great effect on stabilizing thedose response related to absorbency and reducing the auto-oxidization of ferrous ions. Acareful doping with Glc could slow down the color change of the dosimeter before and afterradiation without any effect on the sensitivity of the dosimeter.

      • KCI등재

        Exothermic effects and related surface properties of the ex situ presulfurized catalysts in fabrication and activation

        Yulan Gao,Xiangchen Fang,Zhenmin Cheng,Liming Xu,Zhenhui Lu,Shanda Wang 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.26 No.-

        An ex-situ presulfurization technology for transforming the metal oxides of hydrotreating catalyst to the corresponding metal oxy-sulfides was developed, involving pre-dispersion of an organo-nitrogen substance onto catalyst and a subsequent multi-step heat treatment. The inherence of exothermic effect involved in the ex situ pre-sulfurized catalyst fabrication and activation, and particularly the relationship between the exothermic effect and the surface property of catalyst were investigated. The results indicated that both the preparation parameters and the operating conditions can have effects on the exothermic behavior and surface state of the catalyst. The information obtained in the current study is useful for optimizing the EPRES process, essential for hydrotreating catalyst and its application.

      • KCI등재

        Effect of abdominal acupuncture combined with routine rehabilitation training on shoulder-hand syndrome after stroke: A randomized controlled trial

        Zhan Jie,Ai Yirang,Zhan Lechang,Pan Ruihuan,Wang Yiqiao,Dong Cong,Wang Qiuchun,Chen Hongxia,Lu Liming,Li Mei 한국한의학연구원 2022 Integrative Medicine Research Vol.11 No.2

        Background: Post-stroke shoulder-hand syndrome (SHS) is a common complication after stroke. To date, there is still a lack of consistently effective and good patient compliance methods for SHS. Methods: Fifty patients with SHS were included in this study. Patients in the control group received rehabilitation training (RT) for 2 weeks; each session was 30 min, 1 time per day, and 5 times per week. Patients in the observation group were additionally given Bo’s abdominal acupuncture (BAA) with the same frequency and duration. The primary outcome was the change value in the VAS score from baseline to 2 weeks. The secondary outcomes measured were motor function of the upper limb, shoulder range of motion, ADL, and swelling volume. Results: Compared with baseline values, the mean VAS score at 2 weeks was reduced by 3.68 in the observation group and by 1.92 in the control group, with a difference between the two groups of 1.84 (P < 0.001); the mean MBI score at 2 weeks increased by 10.44 in the observation group and by 4.79 in the control group, with a difference between the two groups of 5.84 (P = 0.032); the mean swelling volume at 2 weeks decreased by 9.64 in the observation group and by 3.29 in the control group, with a difference between the two groups of 6.48 (P < 0.001). BAA-related adverse events were not found during the study. Conclusions: BAA combined with RT is superior to RT alone in improving shoulder pain, swelling, and ADL in post-stroke SHS patients. Trial Registration: ChiCTR2100045464 (www.chictr.org.cn).

      • KCI등재

        Identification of pathways and genes associated with cerebral palsy

        Qingwen Zhu,Yufei Ni,Jing Wang,Honggang Yin,Qin Zhang,Lingli Zhang,Wenjun Bian,Bo Liang,Lingyin Kong,Liming Xuan,Naru Lu 한국유전학회 2018 Genes & Genomics Vol.40 No.12

        Cerebral palsy (CP) is a non-progressive neurological disease, of which susceptibility is linked to genetic and environmental risk factors. More and more studies have shown that CP might be caused by multiple genetic factors, similar to other neurodevelopmental disorders. Due to the high genetic heterogeneity of CP, we focused on investigating related molecular pathways. Ten children with CP were collected for whole-exome sequencing by next-generation sequencing (NGS) technology. Customized processes were used to identify potential pathogenic pathways and variants. Three pathways (axon guidance, transmission across chemical synapses, protein–protein interactions at synapses) with twenty-three genes were identified to be highly correlated with CP. This study showed that the three pathways associated with CP might be the molecular mechanism of pathogenesis. These findings could provide useful clues for developing pathway-based pharmacotherapies. Further studies are required to confirm potential roles for these pathways in the pathogenesis of CP.

      • KCI등재

        Family History, Tobacco Smoking, and Risk of Ischemic Stroke

        Mengyu Fan,Jun Lv,Canqing Yu,Yu Guo,Zheng Bian,Songchun Yang,Ling Yang,Yiping Chen,Feifei Li,Yaoming Zhai,Ping Wang,Junshi Chen,Zhengming Chen,Lu Qi,Liming Li 대한뇌졸중학회 2019 Journal of stroke Vol.21 No.2

        Background and Purpose Both genetic factors and smoking are associated with ischemic stroke (IS) risk. However, little is known about the potential interaction of these factors. We aimed to assess whether smoking and a positive family history interact to increase the risk of IS. Methods The nationwide prospective study recruited 210,000 men and 300,000 women in 2004 to 2008 at ages 30 to 79 years. During 9.7 years of follow-up, we documented 16,923 and 20,656 incident IS cases in men and women without major chronic diseases at baseline, respectively. Multivariable Cox regression models were used to examine associations between family history and IS. Likelihood ratio tests were used to test the smoking-family history interactions on IS. Results About 67.8% (n=135,168) of men ever smoked regularly compared with 2.7% (n=7,775) of women. Among men, a significant interaction between family history and smoking on IS was observed (P for interaction=0.03), with more pronounced association between family history and IS among ever-regular smokers (hazard ratio [HR], 1.21; 95% confidence interval [CI], 1.16 to 1.27) than among never-smokers (HR, 1.11; 95% CI, 1.01 to 1.23). The association between family history and IS among ex-smokers after more than 10 years of cessation (HR, 1.01; 95% CI, 0.85 to 1.20) appeared similar to that among never-smokers. Among women, a similar but not significant interaction between family history and smoking on IS was observed. Ever-regular smokers who had a family history of stroke had the highest risk of IS. Conclusions Among Chinese men, the association of family history with IS was accentuated by smoking, and such accentuation tended to be lowered by cessation.

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