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Artymovich, K.,Kim, J.S.,Linz, J.E.,Hall, D.F.,Kelley, L.E.,Kalbach, H.L.,Kathariou, S.,Gaymer, J.,Paschke, B. Academic Press 2013 Food microbiology Vol.34 No.2
Campylobacter jejuni is an important foodborne pathogen of humans and its primary reservoir is the gastrointestinal (GI) tract of chickens. Our previous studies demonstrated that phase variation to specific ''successful alleles'' at C. jejuni contingency loci Cj0045 (successful alleles carry 9G or 10G homopolymeric tracts) and Cj0170 (successful allele carries a 10G homopolymeric tract) in C. jejuni populations is strongly associated with colonization and enteritis in C57BL/6 IL-10 deficient mice. In the current study, we strengthened the association between locus Cj0170, Cj0045, and mouse colonization. We generated 8 independent strains derived from C. jejuni 11168 strain KanR4 that carried a Cj0170 gene disruption and these were all non motile. Two randomly chosen strains with the Cj0170 gene disruption (DM0170-2 and DM0170-6) were gavaged into mice. DM0170-2 and DM0170-6 failed to colonize mice while the control strain that carried a ''successful''Cj0170 10G allele was motile and did colonize mice. In parallel studies, when we inoculated C. jejuni strain 33292 into mice, the ''unsuccessful''Cj0045 11G allele experienced phase variation to ''successful'' 9G and 10G alleles in 2 independent experiments prior to d4 post inoculation in mice while the ''successful'' 9G allele in the control strain remained stable through d21 post inoculation or shifted to other successful alleles. These data confirm that locus Cj0170 regulates motility in C. jejuni strain KanR4 and is a virulence factor in the mouse model. The data also support a possible role of locus Cj0045 as a virulence factor in strain 33292 in infection of mice.
Spiral density waves in a young protoplanetary disk
Pé,rez, Laura M.,Carpenter, John M.,Andrews, Sean M.,Ricci, Luca,Isella, Andrea,Linz, Hendrik,Sargent, Anneila I.,Wilner, David J.,Henning, Thomas,Deller, Adam T.,Chandler, Claire J.,Dullemond, American Association for the Advancement of Scienc 2016 Science Vol.353 No.6307
<P>Gravitational forces are expected to excite spiral density waves in protoplanetary disks, disks of gas and dust orbiting young stars. However, previous observations that showed spiral structure were not able to probe disk midplanes, where most of the mass is concentrated and where planet formation takes place. Using the Atacama Large Millimeter/submillimeter Array, we detected a pair of trailing symmetric spiral arms in the protoplanetary disk surrounding the young star Elias 2-27. The arms extend to the disk outer regions and can be traced down to the midplane. These millimeter-wave observations also reveal an emission gap closer to the star than the spiral arms. We argue that the observed spirals trace shocks of spiral density waves in the midplane of this young disk.</P>
Florian Tobias Alwin Kretz,Rahmin Khoramnia,Mary Safwat Attia,Michael Janusz Koss,Katharina Linz,Gerd Uwe Auffarth 대한안과학회 2016 Korean Journal of Ophthalmology Vol.30 No.5
Purpose: To evaluate postoperative outcomes and visual performance in intermediate distance afterimplantation of a +1.5 diopters (D) addition, aspheric, rotational asymmetric multifocal intraocularlens (MIOL). Methods: Patients underwent bilateral cataract surgery with implantation of an aspheric, asymmetricMIOL with +1.5 D near addition. A complete ophthalmological examination was performed preoperativelyand 3 months postoperatively. The main outcome measures were monocular and binocularuncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), uncorrectedintermediate visual acuity (UIVA), distance corrected intermediate visual acuity (DCIVA), uncorrectednear visual acuity (UNVA) and distance corrected keratometry, and manifest refraction. The SalzburgReading Desk was used to analyze unilateral and bilateral functional vision with uncorrected and correctedreading acuity, reading distance, reading speed, and the smallest log-scaled print size that could be read effectivelyat near and intermediate distances. Results: The study comprised 60 eyes of 30 patients (mean age, 68.30 ± 9.26 years; range, 34 to 80years). There was significant improvement in UDVA and CDVA. Mean UIVA was 0.01 ± 0.09 logarithmof the minimum angle of resolution (logMAR) and mean DCIVA was -0.02 ± 0.11 logMAR. In Salzburg ReadingDesk analysis for UIVA, the mean subjective intermediate distance was 67.58 ± 8.59 cm with meanUIVA of -0.02 ± 0.09 logMAR and mean word count of 96.38 ± 28.32 words/min. Conclusions: The new aspheric, asymmetric, +1.5 D near addition MIOL offers good results for distancevisual function in combination with good performance for intermediate distances and functionalresults for near distance.
Dust properties across the CO snowline in the HD 163296 disk from ALMA and VLA observations
Guidi, G.,Tazzari, M.,Testi, L.,de Gregorio-Monsalvo, I.,Chandler, C. J.,Pé,rez, L.,Isella, A.,Natta, A.,Ortolani, S.,Henning, Th.,Corder, S.,Linz, H.,Andrews, S.,Wilner, D.,Ricci, L.,Carpenter, Springer-Verlag 2016 Astronomy and astrophysics Vol.588 No.-
Rings and gaps in the disc around Elias 24 revealed by ALMA
Dipierro, G,Ricci, L,Pé,rez, L,Lodato, G,Alexander, R D,Laibe, G,Andrews, S,Carpenter, J M,Chandler, C J,Greaves, J A,Hall, C,Henning, T,Kwon, W,Linz, H,Mundy, L,Sargent, A,Tazzari, M,Testi, L,W Oxford University Press 2018 Monthly notices of the Royal Astronomical Society Vol.475 No.4