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      • 벡터利得 雙行列게임과 多目的計劃法

        丁奎連 崇田大學校 1984 論文集 Vol.14 No.1

        In this paper vector-payoff bimatrix game is developed and quadratic programming which is one of the solution methods of bimatrix game is extended to vector-payoff bimatrix game. Considering the multiobjective of vector-payoff bimatrix game, the relationship between the multiobjective linear programming and this game is developed partially.

      • 다모수 계획법을 이용한 다목적 선형문제의 해법 연구

        정규련 崇實大學校 生産技術硏究所 1994 論文集 Vol.24 No.-

        This paper deals with a solution method of multi-objective linear programming (MOLP) problem using multi-parametric linear programming (MPLP). Transforming MOLP problem to an ε-constraint model that is a form of MPLP, this study shows that all efficient solutions of the problem can be found by solving the multi-parametric solutions. This algorithm provides the trade-off values between objectives explicitely and decides an efficient face on the parameter space directly. This method is relatively more efficient than other method when the number of decision variables is greater than the number of constraints.

      • KCI등재

        支配關係를 利用한 順位化法

        박상규,정규련 한국경영과학회 1992 韓國經營科學會誌 Vol.17 No.2

        In this paper fuzzy ranking method using dominance relation is suggested. This method is compared to the existing fuzzy number comparing methods. All ten methods with the suggested method are evaluated using six examples based on four criteria.

      • 퍼지종속관계를 이용한 다기준 평가문제의 가중치 책정방법

        정택수,정규련 한국경영과학회 1994 한국경영과학회 학술대회논문집 Vol.- No.1

        Scientific involvement in complex decision-making systems, characterized by multicriteria phenomena and fuzziness inherent in the structure of information, requires suitable methods. Especially, when powerful dependent criteria are introduced, the systems are become more complex. This paper presents a fuzzy dependence relation model for this kind of multicriteria decision-making. The model we propose is based on fuzzy relation in fuzzy systems theory. For the application of the model a numerical example is quoted.

      • KCI등재

        퍼지교차종속관계를 이용한 다기준평가문제의 가중치 책정방법

        정규련,정택수 한국경영과학회 1994 韓國經營科學會誌 Vol.19 No.3

        Complex decision-making problems are often characterized by multicriteria phenomena and fuzziness inherent in the structure of information and therefore require suitable scientific solution methods. Especially, when similar dependent criteria are introduced, the problems become more complex. This paper presents a fuzzy intersectional dependence relation model for this kind of multicriteria decision-making problems. The model we propose is based on the fuzzy relation from fuzzy systems theory. In the case of introducing similar dependent criteria, the rank reversal by distortion of weights is hard to occur by our proposed method. A numerical example is presented to illustrate the use of the model.

      • Fuzzy 計劃法에 의한 多目的線型計劃 問題의 部分解

        丁奎連 崇實大學校 1987 論文集 Vol.17 No.-

        The purpose of this paper is to find one efficient face of Multi-Objective Linear Programming (MOLP) problem containing a fuzzy solution using Fuzzy Linear Programming and the right-hand-side multi-parameter. This algorithm provides the trade-off values between objectives explicitly and decides an efficient face on the parameter space directly without the complicated combination procedure of efficient extreme points as another methods do.

      • KCI등재

        초등 국어 교과서에 나타난 아동 권리에 관한 연구

        정대련 ( Chung Dae-ryun ),최은규 ( Choi Eun-kyu ) 한국아동권리학회 2001 아동과 권리 Vol.5 No.2

        본 연구는 아동 권리 교육의 현주소를 살피기 위한 일환으로, 초등학교 국어 교과서에 수록된 동화들이 아동의 권리를 어떻게 표현하고 있는지를 살펴보는 데에 그 목적을 두고 있다. 연구 대상은 2001년 5월 현재 초등 국어 교과서 24권에 수록된 동화 112편이며, 54개조의 아동권리협약 중 4개 원칙에 따라, 즉 생존권·보호권·발달권·참여권 등의 측면에서 동화의 내용을 분석하였다. 112편의 동화 중 창작동화는 82편, 전래동화가 30편이며, 국내 및 외국동화는 각각 102편과 10편이다. 연구결과에 따르면, 초등 국어 교과서에 수록된 동화는 생존·보호·발달·참여 등 권리의 4개 원칙 각각을 긍정적으로 반영하고 있다. 또한 창작동화가 전래동화보다 아동의 생존권을 좀 더 적극적이고 긍정적으로 표현하고 있다. This study is to analyze the children's right sex pressed in the stories of elementary textbooks for Korean Language & Literature. UN Convention of Children's Rights are based upon the 4 principles, Rights of Survival, Rights of Protection, Rights of Development and Rights of Participation. 112 stories from 24 textbooks were chosen for this study. Of the 112 stories, 102 were domestic and 10 were foreign stories; which included the 82 creative stories and 30 folk tales. All four rights of survival, protection, development, and participation are expressed positively in most stories of the elementary textbooks for Korean Language & Literature. However the four rights are expressed more positively and affirmatively in the creative stories than in the folk tales. The results of this study are as follows. 1) 52 stories related positively to the articles 6, 24, 27 express the Rights of Survival. 28.85% of the stories imply negative meanings of children's rights. 2) The Rights of Protection in the stories are related to the articles 2 and 20. 40.26% of the stories reflect negatively against the children's rights. And the meanings of several articles about the protection for children are not expressed in the textbooks. 3) The Rights of Development of the articles 7 and 28 are expressed in most of the stories. Children's rights are expressed positively in 92.31% and negatively in 7.69% of the stories. 4) The rights of participation in the children's stories are focused up on the article 12. 90.79% of the stories imply positive view points of children's participation, but the rest 9.21% imply negative view points.

      • Distinct clinical features and outcomes in never‐smokers with nonsmall cell lung cancer who harbor <i>EGFR</i> or <i>KRAS</i> mutations or <i>ALK</i> rearrangement

        Kim, Hye Ryun,Shim, Hyo Sup,Chung, Jin‐,Haeng,Lee, Young Joo,Hong, Yun Kyoung,Rha, Sun Young,Kim, Se Hoon,Ha, Sang‐,Jun,Kim, Se Kyu,Chung, Kyung Young,Soo, Ross,Kim, Joo Hang,Cho, Byoung C Wiley Subscription Services, Inc., A Wiley Company 2012 Cancer Vol.118 No.3

        <P><B>Abstract</B></P><P><B>BACKGROUND:</B></P><P>The objectives of this study were to determine the proportions of major oncogenic alterations and to examine survival in genotype‐specific subsets of never‐smokers with nonsmall cell lung cancer (NSCLC).</P><P><B>METHODS:</B></P><P>The authors concurrently analyzed mutations in the epidermal growth factor receptor (<I>EGFR</I>) and v‐Ki‐<I>ras</I>2 Kirsten rat sarcoma viral oncogene homolog (<I>KRAS</I>) genes and investigated anaplastic lymphoma kinase (<I>ALK</I>) gene rearrangements in samples from 229 never‐smokers with NSCLC. <I>ALK</I> rearrangements were identified by fluorescent in situ hybridization and were confirmed by immunohistochemistry. Mutations in <I>EGFR</I> (exons 18 to 21) and <I>KRAS</I> (codons 12 and 13) were determined by direct sequencing.</P><P><B>RESULTS:</B></P><P>Of 229 tumors, the frequency of <I>EGFR</I> mutations, <I>ALK</I> rearrangements, <I>KRAS</I> mutations, and no mutations (wild type [WT]) in any of the 3 genes (<I>WT/WT/WT</I>) was 48%, 8.3%, 3.5%, and 40.2%, respectively. All genetic alterations were mutually exclusive. The median progression‐free survival after treatment with EGFR tyrosine kinase inhibitors (TKIs) was 12.8 months, 6.3 months, 2.1 months, and 1.6 months in patients with <I>EGFR</I> mutations, the <I>WT/WT/WT</I> genotype, <I>KRAS</I> mutations, and <I>ALK</I> rearrangements, respectively. In a Cox regression model, the adjusted hazard ratio for the risk of disease progression after treatment with EGFR TKIs was 0.59 (95% confidence interval [CI], 0.40‐0.87; <I>P</I> = .008) for patients with <I>EGFR</I> mutations, 4.58 (95% CI, 2.07‐10.15; <I>P</I> < .001) for patients with <I>ALK</I> rearrangements, and 4.23 (95% CI, 1.65‐10.8; <I>P</I> = .003) for patients with <I>KRAS</I> mutations. Overall survival also differed significantly among genotypes.</P><P><B>CONCLUSIONS:</B></P><P>To the authors' knowledge, this was the largest comprehensive and concurrent analysis to date of 3 major oncogenic alterations in a cohort of East Asian never‐smokers with NSCLC. Because survival outcomes differed among genotypes, and drugs that target specific alterations currently are available, genetic profiling to identify genotype‐specific subsets can lead to successful treatment with appropriate kinase inhibitors. Cancer 2012;. © 2011 American Cancer Society.</P>

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