지역 공간DB의 Web Service 방안

김동문,신은솔 남서울대학교 2009 남서울대학교 논문집 Vol.15 No.2

As an increasing interest in GIS, it has been used in many fields such as urban planning, environment, military. Due to the ubiquitous internet, the number of users are able to take advantage of GIS without the constraints of time and space. However, local government such as Cheonan city does not serve local spatial database properly to user. Therefore, this research proposed the methodologies that can be served effectively local spatial database by combining internet and GIS. To achieve the research purpose, open APIs of Google Earth and mashup techniques were used. Key Words : Geographic Information System, Spatial Database, Open API, Mashup

석면함유 슬레이트 지붕 물받이 퇴적물 중 석면 섬유 함유율

임지현,한솔민,김현석,신유민,박시은,허정윤,김민영,장봉기 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

This study attempted to determine the degree of asbestos release from the aging slate roof by comparing the asbestos content in the slate roof rain gutter with a colored steel plate (tin plate) over the slate roof. Four slate roof houses located in Haengmok-ri, Asan-si, Chungcheongnam-do, and one house constructed with a colored steel plate on the slate roof were selected to collect the sediment of the roof rain gutter. The asbestos fiber content was calculated by a point counting method using a polarization microscope after pretreatment with conversion treatment and hydrochloric acid treatment. The average asbestos content of the four slate roof rain gutter were 1.89%. However, asbestos was not detected in the Slate covering roof rain gutter, which were constructed on the slate roof. Asbestos fiber content was the highest at 2.89% in the slate roof rain gutter installed in 1976, followed by 2.44% in 1953. From the above results, it is necessary to minimize secondary damage as asbestos fibers released from slate roof houses to the surrounding atmosphere or leaked from slate roofs as rainwater may cause soil pollution and seriously affect residents' health. Although covering with colored steel plates (tin plates) has been shown to prevent the leakage of asbestos fibers to some extent, it is believed that a policy alternative to remove the slate roof as soon as possible is needed to solve the fundamental problem.

The Effects of Physical Fitness and Satisfaction on According to Different Exercise Method in College Students

( Bog Ja Jeoung ),( Yu Jin Jeong ),( Eun Bin Kim ),( Eun Sol Cho ) 한국체육학회 2015 국제스포츠과학 학술대회 Vol.2015 No.1

Purpose : In previous researches, we learned that exercising promotes physical fitness ,strength and positive change in the physical satisfaction level but reviewing previous researches, there was a limit in our finding as it was based on a singular physical activity or exercise and we could not exactly find out which exercise provided the most physical change and satisfaction level. Therefore, the purpose of this study was to find out effects of physical fitness and satisfaction according to participate in exercise method(circuit strength, weight bearing program and badminton). Method: Twelve college students participated exercise program(circuit strength program : n=4, weight bearing program : n=4 and badminton : n=4) who measured 20m PACER, push-up, grip strength, sit-up and sit-reach and body composition, and satisfaction which ``Sports Participants Satisfaction Questionnaire`` developed by Yoo et al(2010). The questionnaire covered improving physical function (3), improved exercise capacity (3), promote social and psychological benefits (3), two healthy living (2) which consisted of total of 14 questions with 5 multiple choices. With regard to the body satisfaction level survey, we have used the BSQ: Body Shape Questionnaire developed in 1987 by Cooper, Taylor and Fairvurn. Park, Eun-ah and Noh, Young-kyung was edited the BSQ questionnaire for this research. The body satisfaction level survey consisted of four sub-variables and a total of 27 questions. Result: First, there is a high level of increase overall in physical strength measurement results especially in sit-ups, flexibility, push-ups and cardiovascular endurance. However, there was little difference between the groups in terms stamina changes while we could not compare physical strength changes based on the type of exercise. Second, there was a slight decrease in weight, BMI, waist and hip circumference with regard to physical changes. However, the physical changes between groups were small while there was no physical change based on the type of exercise. In addition, the was no changes in the level of satisfaction based on after and before exercising while there was only slight difference exercise groups. Third, overall satisfaction level showed significant increase among the exercise groups while the health exercise showed the highest level of satisfaction followed by badminton and circuit training. In terms of exercise satisfaction level by category, physical function improvement and improved exercise capacity showed the highest level of increase and there was little difference in the exercise satisfaction level based on the exercise type. Fourth, if we look at the satisfaction level for physical strength change, satisfaction level was high for strength and agility category but showed no changes between exercise groups. Conclusion: This research is the study of the satisfaction level and changes in physical and physical strength based on three different exercises for different exercise groups. Based on the results of the study, exercising regularly helps increase the overall physical level in all exercise groups and the satisfaction level gradually increases. However, there was little difference between the exercise groups and this research was unable to verify the difference based on the exercise groups. Since the research was limited to 12 participants, a follow-up research should be conducted based on an extended level of participants.

Serum clusterin level in children with atopic dermatitis

Sol, In Suk,Kim, Yoon Hee,Lee, Kyung Eun,Hong, Jung Yeon,Kim, Mi Na,Kim, Yun Seon,Oh, Mi Seon,Kim, Min Jung,Yoon, Seo Hee,Park, Young A.,Kim, Kyung Won,Sohn, Myung Hyun,Kim, Kyu-Earn Oceanside Publications 2016 Allergy and asthma proceedings Vol.37 No.4

Fabrication and Challenges of Cu-to-Cu Wafer Bonding

Kang, Sung-Geun,Lee, Ji-Eun,Kim, Eun-Sol,Lim, Na-Eun,Kim, Soo-Hyung,Kim, Sung-Dong,Kim, Sarah Eun-Kyung The Korean Microelectronics and Packaging Society 2012 마이크로전자 및 패키징학회지 Vol.19 No.2

The demand for 3D wafer level integration has been increasing significantly. Although many technical challenges of wafer stacking are still remaining, wafer stacking is a key technology for 3D integration due to a high volume manufacturing, smaller package size, low cost, and no need for known good die. Among several new process techniques Cu-to-Cu wafer bonding is the key process to be optimized for the high density and high performance IC manufacturing. In this study two main challenges for Cu-to-Cu wafer bonding were evaluated: misalignment and bond quality of bonded wafers. It is demonstrated that the misalignment in a bonded wafer was mainly due to a physical movement of spacer removal step and the bond quality was significantly dependent on Cu bump dishing and oxide erosion by Cu CMP.

Paclitaxel-loaded Gelatin Nanoparticles Prepared by Sinlgle Process O/W/O emulsion

Eun Ju LEE,Han Sol KWon,Su Hyeon KIM,You Jin PARK,Jeong Eun KIM,Kwang-Hee LIM 한국생물공학회 2017 한국생물공학회 학술대회 Vol.2017 No.4

Anti-inflammatory Effect of Glucagon Like Peptide-1 Receptor Agonist, Exendin-4, through Modulation of IB1/JIP1 Expression and JNK Signaling in Stroke

Kim, Soojin,Jeong, Jaewon,Jung, Hye-Seon,Kim, Bokyung,Kim, Ye-Eun,Lim, Da-Sol,Kim, So-Dam,Song, Yun Seon The Korean Society for Brain and Neural Science 2017 Experimental Neurobiology Vol.26 No.4

<P>Glucagon like peptide-1 (GLP-1) stimulates glucose-dependent insulin secretion. Dipeptidyl peptidase-4 (DPP-4) inhibitors, which block inactivation of GLP-1, are currently in clinical use for type 2 diabetes mellitus. Recently, GLP-1 has also been reported to have neuroprotective effects in cases of cerebral ischemia. We therefore investigated the neuroprotective effects of GLP-1 receptor (GLP-1R) agonist, exendin-4 (ex-4), after cerebral ischemia-reperfusion injury. Transient middle cerebral artery occlusion (tMCAO) was induced in rats by intracerebroventricular (i.c.v.) administration of ex-4 or ex9-39. Oxygen-glucose deprivation was also induced in primary neurons, bEnd.3 cells, and BV-2. Ischemia-reperfusion injury reduced expression of GLP-1R. Additionally, higher oxidative stress in SOD2 KO mice decreased expression of GLP-1R. Downregulation of GLP-1R by ischemic injury was 70% restored by GLP-1R agonist, ex-4, which resulted in significant reduction of infarct volume. Levels of intracellular cyclic AMP, a second messenger of GLP-1R, were also increased by 2.7-fold as a result of high GLP-1R expression. Moreover, our results showed that ex-4 attenuated pro-inflammatory cyclooxygenase-2 (COX-2) and prostaglandin E<SUB>2</SUB> after MCAO. C-Jun NH<SUB>2</SUB> terminal kinase (JNK) signaling, which stimulates activation of COX-2, was 36% inhibited by i.c.v. injection of ex-4 at 24 h. Islet-brain 1 (IB1), a scaffold regulator of JNK, was 1.7-fold increased by ex-4. GLP-1R activation by ex-4 resulted in reduction of COX-2 through increasing IB1 expression, resulting in anti-inflammatory neuroprotection during stroke. Our study suggests that the anti-inflammatory action of GLP-1 could be used as a new strategy for the treatment of neuroinflammation after stroke accompanied by hyperglycemia.</P>

Assessing the Impact of Aging on Burden of Disease

KIM, Eun-Jung,JUNG, Sung-Won,KIM, Young-Eun,GO, Dun-Sol,YOON, Seok-Jun Tehran University of Medical Sciences 2018 Iranian journal of public health Vol.47 No.1

<P><B>Background:</B></P><P>In this study, we presented a theoretical model to measure aging rate in OECD countries, quantitatively measuring the effect of aging rate on disease patterns in each country and explaining how these effects were obtained. The purpose of this study was to investigate how disease burden varies according to the level of medical infrastructure and changes in aging index using OECD aging data and WHO disease burden data.</P><P><B>Methods:</B></P><P>This study used OECD Health data and global burden of disease data from the WHO in 2000 and 2012. We applied a difference-in-differences (DID) model was used to analyze effects of aging.</P><P><B>Results:</B></P><P>Disease burdens increased over time, especially in the aging population of middle-aged. In the case of loss of life due to premature death, the number of middle-aged and older population was increased significantly. When we examined the econometric model after controlling related factors, there was a significant increase in loss of life due to illness and premature death. On the other hand, the group of piles at the aging level had a significant positive effect on Years of Life Lost (YLL). Although the interaction effect as an important variable showing double difference effect of aging did not affect Disability adjusted Life Year (DALY), it showed a significant positive effect on YLL.</P><P><B>Conclusion:</B></P><P>Loss of life due to death of the elderly was relatively higher than that of the elderly. Therefore, the impact of population aging on medical resources and medical expenditures in the future should consider population structure changes, disease burden by age group, and interactions of these two incremental factors.</P>

Scale-up Study of the Non-structural Protein Removal Method Using Chloroform for Foot-and-mouth Disease Vaccine Production

Eun-Sol KIM,Sun Young PARK,Ah-Young KIM,Sang Hyun PARK,Jong-Hyeon PARK,Young-Joon KO 한국생물공학회 2021 한국생물공학회 학술대회 Vol.2021 No.10

Foot-and-mouth disease (FMD) is an economically important and highly infectious viral disease in most parts of the world and is predominantly controlled by immunization strategy. The removal of nonstructural proteins (NSPs) is an important process of FMD vaccine because vaccinated and naturally infected animals can be distinguished by the presence of NSP antibodies in FMD serological surveillance. Polyethylene glycol method is conventionally used to eliminate the NSPs from the FMD vaccine antigens. However, since this method leaves residual NSPs, we established a method to remove NSPs by chloroform treatment. The NSPs were not detected in treatment with more than 2% chloroform in the FMD virus (FMDV) culture supernatant. It was verified that the chloroform treated FMD vaccine eliminated NSPs by animal immunization. For industrial application, the mixing volume of the FMDV culture supernatant and chloroform was scaled-up. In a 2 liter bioreactor, 2% of chloroform and 2,000rpm of impeller speed were established as an optimal mixing condition. Using an electronic mixer, 2% of chloroform and 350rpm of agitator speed were established in a volume of 20 liters.In conclusion, a method for removing NSPs with minimum concentration of chloroform was developed. Furthermore, by scaling up this, it is expected that FMD vaccine manufacturers could be able to easily produce high-purity FMD vaccines.

Prescription Patterns and Burden of Pediatric Asthma in Korea

Sol, In Suk,Kim, Yoon Hee,Kim, Soo Yeon,Choi, Sun Ha,Kim, Jong Deok,Kim, Bo Ok,Moon, Ji Eun,Kim, Kyung Won,Sohn, Myung Hyun The Korean Academy of Asthma, Allergy and Clinical 2019 Allergy, Asthma & Immunology Research Vol.11 No.2

<P><B>Purpose</B></P><P>This study aimed to estimate the prevalence, prescription pattern and burden of pediatric asthma in Korea by analyzing the National Health Insurance (NHI) claims data.</P><P><B>Methods</B></P><P>We retrospectively analyzed the insurance claim records from the Korean NHI claims database from January 2010 to December 2014. Asthmatic patients were defined as children younger than 18 years, with appropriate 10th Revision of the International Classification of Diseases codes (J45 or J46) and a prescription for 1 or more asthma maintenance medications at the same date. Hospitalization and emergency department visits for asthma were defined as use of short-acting beta<SUB>2</SUB>-agonists during hospital visits among asthmatic patients.</P><P><B>Results</B></P><P>There were 1,172,807 asthmatic children in 2010, which increased steadily to 1,590,228 in 2014 in Korea. The prevalence showed an increasing trend annually for all ages. The mean prevalence by age in those older than 2 years decreased during the study period (from 39.4% in the 2–3 year age group to 2.6% in the 15–18 year age group). In an outpatient prescription, leukotriene receptor antagonists were the most commonly prescribed medication for all ages. Patients older than 6 years for whom inhaled corticosteroids were prescribed comprised less than 15% of asthmatic patients. The total direct medical cost for asthma between 2010 and 2014 ranged from $376 to $483 million. Asthma-related medical cost per person reached its peak in $366 in 2011 and decreased to $275 in 2014.</P><P><B>Conclusions</B></P><P>The prevalence of pediatric asthma increased annually and decreased with age. Individual cost of asthma showed a decreasing trend in Korean children.</P>