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      • Thermoelastic bending analysis of laminated plates subjected to linear and nonlinear thermal loads

        Swami, Sandhya K.,Ghugal, Yuwaraj M. Techno-Press 2021 Advances in aircraft and spacecraft science Vol.8 No.3

        The paper presents the analytical solutions for thick orthotropic laminated plates using trignometric shear deformation theory. The effects transverse shear and transverse normal strains are included with linear and nonlinear thermal loads. The displacement field of the theory includes the trigonometric functions in thickness coordinate of plate to account for these effects. The displacement field enforces to give the realistic variation of shear stresses across the thickness of plate and thus obviates the need of shear correction factor. The main novelty of the present study is the inclusion of thickness stretching effect in the theory. Another novelty is the application of nonlinear thermal profile consistent with the displacement field of the theory. The principle of virtual work is used to obtain the governing equations and boundary conditions. Simply supported laminated square plates are considered for numerical study to evaluate thermoelastic response. The results obtained by present theory with thickness stretching effect are compared with other refined theories disregarding this effect. It is observed that the results of present theory deviate significantly from the results of other higher order shear deformation theories for antisymmetric crossply laminated plates. The results of symmetric cross-ply laminated plates subjected to linear sinusoidal thermal load are in close agreement with those of exact theory, which validates the accuracy of present shear and normal deformation theory.

      • KCI등재

        qMon: A Method to Monitor Queueing Delay in OpenFlow Networks

        Sandhya Rathee,Shubham Tiwari,K Haribabu,Ashutosh Bhatia 한국통신학회 2022 Journal of communications and networks Vol.24 No.4

        In software-defined networking (SDN), the decou- pled architecture provides opportunities for efficiently measuring critical quality of service (QoS) parameters, such as delay. Existing approaches, to dynamically obtain delay, are based around calculating the transit time of a probe packet that travels through the data links. These approaches are not efficient as the probe packet injected into the data plane incurs considerable overhead. Additionally, a separate probe packet is required to measure the delay of each queue if more than one queue is present on the egress port of a switch. Thus, these approaches are not scalable. In this paper, we propose an efficient passive delay estimation method, queueing delay monitoring (qMon), to monitor queueing delay in SDN networks. qMon leverages the OpenFlow protocol to obtain queue statistics from switches at regular intervals, which are further employed to estimate the mean queueing delay for each interval. Thus, the proposed approach differs from the existing approaches as no packet is injected into the data plane to measure delay. The results show that for Poisson traffic and for bursty traffic with large ON intervals, round trip time (RTT) values estimated using qMon and ping utility demonstrate high correlation when the measured RTT value is considered as time-series data.

      • Enhancing Gender Classification in Social Networks

        S. Nalini,K. Sandhya,P. Ganesh Kumar 한국산업정보학회 2014 한국산업정보학회 학술대회논문집 Vol.2014 No.1

        Posts in social networking sites are informal, personal writings that people post on their own blog or sites. Nowadays, blogging in Social Networks are an important online activity. With the rapid growth of blogs in Social Network, their value as an important source of information is increasing. A large amount of research work has been devoted to blogs in the Natural Language Processing (NLP) and other communities. There are also many commercial companies that exploit information in blogs to provide value-added services, e.g. search, topic tracking, and sentiment analysis of people’s opinions on products and services. The goal of our system is to identify author gender of posts in social networks coming from a wide variety of source. The dataset used is from the popular social network, Twitter. Using the parts of speech of the dataset the gender of the site user is found. Empirical evaluation using a real-life blog data set shows that these two techniques improve the classification accuracy of the current state-of the-art methods significantly.

      • KCI등재

        Effects of hafnium on the structural, optical and ferroelectric properties of sol–gel synthesized barium titanate ceramics

        Fernandez Jude,Bindhu B.,Prabu M.,Sandhya K. Y. 한국세라믹학회 2022 한국세라믹학회지 Vol.59 No.2

        For future electronic devices, barium titanate based multifunctional ceramics falling under the category of ABO 3 perovskite type rose to prominence among scientists and engineers around the world. Moreover, the remarkable properties can be tuned by a strategy known as doping. The synthesis of hafnium (Hf 4+ ) doped BaHf x Ti (1- x ) O 3 , x = 0.00, 0.05, 0.10, 0.15 ceramics based on a wet chemical technique known as sol–gel, where the total time and temperature required for complete phase for- mation is considerably less, is reported in this article. The formation of a well-defined crystal structure with tetragonal phase showing P4mm space group was confirmed for BaHf x Ti (1- x ) O 3 ceramics calcined at 1000 °C using Raman spectroscopy and X-ray diff raction (XRD). The calcined powders consisting of grains with polyhedral shapes possessed particle sizes ranging from 160 to 460 nm. A signifi cant peak corresponding to metal oxide formation was obtained at 565  cm −1 for all the composi- tions in Fourier transform infrared (FTIR) spectra, proving the existence of the required perovskite phase. A minor variation in band gap energy with increase in Hafnium (Hf 4+ ) was found out using Ultraviolet–Visible-near-IR (UV–Visible-NIR) spectroscopy. Photoluminescence (PL) spectrum analysis, put forward the possibility of slight disorders in the ceramics; nonetheless, the spectra were found to be composed of peaks corresponding to blue, red and green emissions. The remnant polarization ( P r ), saturation polarization ( P s ) and coercive electric field ( E c ) of BaHf x Ti (1- x ) O 3 , calculated from ferroelectric hysteresis loop were found to vary appreciably with corresponding rise in hafnium (Hf 4+ ) concentration.

      • Organization, Integration, and Assembly of Genetic and Epigenetic Regulatory Machinery in Nuclear Microenvironments : Implications for Biological Control in Cancer

        Stein, Gary S.,Zaidi, Sayyed K.,Stein, Janet L.,Lian, Jane B.,Van Wijnen, Andre J.,Montecino, Martin,Young, Daniel W.,Javed, Amjad,Pratap, Jitesh,Choi, Je-Yong,Ali, Syed A.,Pande, Sandhya,Hassan, Moha Wiley (Blackwell Publishing) 2009 Annals of the New York Academy of Sciences Vol.1155 No.1

        <P>There is growing awareness that the fidelity of gene expression necessitates coordination of transcription factor metabolism and organization of genes and regulatory proteins within the three-dimensional context of nuclear architecture. The regulatory machinery that governs genetic and epigenetic control of gene expression is compartmentalized in nuclear microenvironments. Temporal and spatial parameters of regulatory complex organization and assembly are functionally linked to biological control and are compromised with the onset and progression of tumorigenesis. High throughput imaging of cells, tissues, and tumors, including live cell analysis, is expanding research's capabilities toward translating components of nuclear organization into novel strategies for cancer diagnosis and therapy.</P>

      • SCISCIESCOPUS

        Transcription-factor-mediated epigenetic control of cell fate and lineage commitmentThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting - Epigenetics and Chromatin Dynamics, and has undergone

        Stein, Gary S.,Zaidi, Sayyed K.,Stein, Janet L.,Lian, Jane B.,van Wijnen, Andre J.,Montecino, Martin,Young, Daniel W.,Javed, Amjad,Pratap, Jitesh,Choi, Je-Yong,Ali, Syed A.,Pande, Sandhya,Hassan, Moha Canadian Science Publishing 2009 Biochemistry and cell biology Vol.87 No.1

        <P> Epigenetic control is required to maintain competency for the activation and suppression of genes during cell division. The association between regulatory proteins and target gene loci during mitosis is a parameter of the epigenetic control that sustains the transcriptional regulatory machinery that perpetuates gene-expression signatures in progeny cells. The mitotic retention of phenotypic regulatory factors with cell cycle, cell fate, and tissue-specific genes supports the coordinated control that governs the proliferation and differentiation of cell fate and lineage commitment. </P>

      • KCI등재

        Comparative transcriptome analysis of two contrasting genotypes provides new insights into the drought response mechanism in pigeon pea (Cajanus cajan L. Millsp.)

        Pahal Suman,Srivastava Harsha,Saxena Swati,Tribhuvan Kishor U.,Kaila Tanvi,Sharma Sandhya,Grewal Sapna,Singh Nagendra K.,Gaikwad Kishor 한국유전학회 2024 Genes & Genomics Vol.46 No.1

        Background Despite plant's ability to adapt and withstand challenging environments, drought poses a severe threat to their growth and development. Although pigeon pea is already quite resistant to drought, the prolonged dehydration induced by the aberrant climate poses a serious threat to their survival and productivity. Objective Comparative physiological and transcriptome analyses of drought-tolerant (CO5) and drought-sensitive (CO1) pigeon pea genotypes subjected to drought stress were carried out in order to understand the molecular basis of drought tolerance in pigeon pea. Methods The transcriptomic analysis allowed us to examine how drought affects the gene expression of C. cajan. Using bioinformatics tools, the unigenes were de novo assembled, annotated, and functionally evaluated. Additionally, a homology-based sequence search against the droughtDB database was performed to identify the orthologs of the DEGs. Results 1102 potential drought-responsive genes were found to be differentially expressed genes (DEGs) between drought-tolerant and drought-sensitive genotypes. These included Abscisic acid insensitive 5 (ABI5), Nuclear transcription factor Y subunit A-7 (NF-YA7), WD40 repeat-containing protein 55 (WDR55), Anthocyanidin reductase (ANR) and Zinc-finger homeodomain protein 6 (ZF-HD6) and were highly expressed in the tolerant genotype. Further, GO analysis revealed that the most enriched classes belonged to biosynthetic and metabolic processes in the biological process category, binding and catalytic activity in the molecular function category and nucleus and protein-containing complex in the cellular component category. Results of KEGG pathway analysis revealed that the DEGs were significantly abundant in signalling pathways such as plant hormone signal transduction and MAPK signalling pathways. Consequently, in our investigation, we have identified and validated by qPCR a group of genes involved in signal reception and propagation, stress-specific TFs, and basal regulatory genes associated with drought response. Conclusion In conclusion, our comprehensive transcriptome dataset enabled the discovery of candidate genes connected to pathways involved in pigeon pea drought response. Our research uncovered a number of unidentified genes and transcription factors that could be used to understand and improve susceptibility to drought. Background Despite plant's ability to adapt and withstand challenging environments, drought poses a severe threat to their growth and development. Although pigeon pea is already quite resistant to drought, the prolonged dehydration induced by the aberrant climate poses a serious threat to their survival and productivity. Objective Comparative physiological and transcriptome analyses of drought-tolerant (CO5) and drought-sensitive (CO1) pigeon pea genotypes subjected to drought stress were carried out in order to understand the molecular basis of drought tolerance in pigeon pea. Methods The transcriptomic analysis allowed us to examine how drought affects the gene expression of C. cajan. Using bioinformatics tools, the unigenes were de novo assembled, annotated, and functionally evaluated. Additionally, a homology-based sequence search against the droughtDB database was performed to identify the orthologs of the DEGs. Results 1102 potential drought-responsive genes were found to be differentially expressed genes (DEGs) between drought-tolerant and drought-sensitive genotypes. These included Abscisic acid insensitive 5 (ABI5), Nuclear transcription factor Y subunit A-7 (NF-YA7), WD40 repeat-containing protein 55 (WDR55), Anthocyanidin reductase (ANR) and Zinc-finger homeodomain protein 6 (ZF-HD6) and were highly expressed in the tolerant genotype. Further, GO analysis revealed that the most enriched classes belonged to biosynthetic and metabolic processes in the biological process category, binding and catalytic activity in the molecular function category and nucleus and protein-containing complex in the cellular component category. Results of KEGG pathway analysis revealed that the DEGs were significantly abundant in signalling pathways such as plant hormone signal transduction and MAPK signalling pathways. Consequently, in our investigation, we have identified and validated by qPCR a group of genes involved in signal reception and propagation, stress-specific TFs, and basal regulatory genes associated with drought response. Conclusion In conclusion, our comprehensive transcriptome dataset enabled the discovery of candidate genes connected to pathways involved in pigeon pea drought response. Our research uncovered a number of unidentified genes and transcription factors that could be used to understand and improve susceptibility to drought.

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