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Economic Paradiplomacy of Canadian provinces in North America
Jorge Virchez(Jorge Virchez ),Roberto Zepeda(Roberto Zepeda ) 한국캐나다학회 2017 Asia-Pacific Journal of Canadian Studies (APJCS) Vol.23 No.2
This article analyzes the international relations of the Canadian provinces in recent decades, especially observing exports and imports with the United States and Mexico, but also in the international arena. The analysis is conducted both from a national and subnational perspective, considering economic patterns and trends. In the same way, we observe the productive activities and the most relevant industries in the economy of the Canadian provinces and their connection with international markets. The aim of this article is to examine the economic relations and international activities of Canadian provinces. We concentrate on the cases of Ontario, Quebec, Alberta and British Columbia. Economic integration in North America has paved the way to other forms of cooperation between subnational governments on diverse topics, through diverse regional organizations and through international agreements.
Jorge A. Gonzalez-y-Merchand,Ruben Zaragoza-Contreras,Rosalina Guadarrama-Medina,Addy C. Helguera-Repetto,Sandra Rivera-Gutierrez,Jorge F. Cerna-Cortes,Leopoldo Santos-Argumedo,Robert A. Cox 한국미생물학회 2012 The journal of microbiology Vol.50 No.3
The study of the in vitro cell growth of mycobacteria still remains a fastidious, difficult, and time-consuming procedure. In addition, assessing mycobacterial growth in the laboratory is often complicated by cell aggregation and slow growth-rate. We now report that the use of a stainless steel spring in the culture led to an absence of large cell clumps, to a decrease of dead cells in the exponential phase and to growth of a more homogeneous population of large cells. We also report that flow cytometry is a rapid, simple and reliable approach to monitor mycobacterial cell growth and viability. Here, we monitored Mycobacterium smegmatis cellular growth by optical density, dry cell mass, and colony forming units; in addition, viability, cell size and granularity profiles were analyzed by flow cytometry, and cell morphology by electron microscopy. Cultures monitored by flow cytometry may lead to a better understanding of the physiology of mycobacteria. Moreover, this methodology may aid in characterizing the cell growth of other fastidious species of microorganisms.
( Jorge Frias ),( Duarte Toubarro ),( Alexandra Fraga ),( Claudia Botelho ),( Jose Teixeira ),( Jorge Pedrosa ),( Nelson Simoes ) 한국미생물생명공학회(구 한국산업미생물학회) 2021 Journal of microbiology and biotechnology Vol.31 No.2
Fibrinolytic enzymes with a direct mechanism of action and safer properties are currently requested for thrombolytic therapy. This paper reports on a new enzyme capable of degrading blood clots directly without impairing blood coagulation. This enzyme is also non-cytotoxic and constitutes an alternative to other thrombolytic enzymes known to cause undesired side effects. Twenty-four Bacillus isolates were screened for production of fibrinolytic enzymes using a fibrin agar plate. Based on produced activity, isolate S127e was selected and identified as B. subtilis using the 16S rDNA gene sequence. This strain is of biotechnological interest for producing high fibrinolytic yield and consequently has potential in the industrial field. The purified fibrinolytic enzyme has a molecular mass of 27.3 kDa, a predicted pI of 6.6, and a maximal affinity for Ala-Ala-Pro-Phe. This enzyme was almost completely inhibited by chymostatin with optimal activity at 48℃ and pH 7. Specific subtilisin features were found in the gene sequence, indicating that this enzyme belongs to the BPN group of the S8 subtilisin family and was assigned as AprE127. This subtilisin increased thromboplastin time by 3.7% (37.6 to 39 s) and prothrombin time by 3.2% (12.6 to 13 s), both within normal ranges. In a whole blood euglobulin assay, this enzyme did not impair coagulation but reduced lysis time significantly. Moreover, in an in vitro assay, AprE127 completely dissolved a thrombus of about 1 cc within 50 min and, in vivo, reduced a thrombus prompted in a rat tail by 11.4% in 24 h compared to non-treated animals.
Spinal Gunshot Wounds: Pattern and Associated Lesions in Civilians
Jorge Arturo Cabrera Escamilla,Jorge Álvaro González Ross,José Manuel Pérez Atanasio,Gustavo Casas Martínez,Arelhi González Cisneros,Jose Jimenez Avila 대한척추외과학회 2018 Asian Spine Journal Vol.12 No.4
Study Design: Retrospective, descriptive case series study. Purpose: To investigate the frequency, bone pattern, and associated lesions to the spine of gunshot wounds. Overview of Literature: Gunshot wounds are penetrating in nature and are caused by a bullet or projectile. These are becoming more common and are associated with significant sequelae, requiring long and costly multidisciplinary treatment. Associated spinal cord injuries (SCIs) in the civilian population represent 13%–17% of all spinal traumas. Spinal gunshot wounds are commonly thought to be stable; however, there is potential acute and chronic spinal instability if the bullet passes transversely, fracturing either both pedicles or both facet joints. Methods: We obtained data from the clinical files of patients with spinal gunshot wounds treated by spine surgeons. We performed a statistical analysis to obtain the pattern and frequency of the injuries. Results: We included 54 patients (48 men [89%] and six women [11%]). Eight patterns of spinal gunshot wounds were identified; 61% (33 patients) had complete SCI. The thoracic spine was most frequently affected, with 88% of patients having SCI; 75%, hemopneumothorax; 28%, pulmonary lesions; and 16%, hepatic lesions. The presence of pedicle fractures had an odds ratio of 3.64 for SCI. Conclusions: The two main bone patterns are the vertebral body and posterior arch with pedicle fractures as modifiers, given that they are at a high risk for SCI. The spinal pattern and associated lesions were related to the bullet’s path, with the vertebral body having the highest frequency of associated lesions. Vertebral body burst fracture was the main indication for instrumentation.
Maria Isabel Sá,nchez Jorge,Jorge Corté,s-Bretó,n Brinkmann,Aranzazu Gonzá,lez Corchó,n,Rosa Acevedo Ocañ,a 대한구강악안면외과학회 2021 대한구강악안면외과학회지 Vol.47 No.4
Hemangioma is a benign tumor characterized by the proliferation of blood vessels. Although it often appears in soft tissues, its occurrence in bone tissue, particularly the mandible, is extremely rare. A 32-year-old female sought attention at the dental clinic complaining of a painless swelling in the posterior region of the left side of the mandible. A panoramic radiograph and computed axial tomography scan were taken, showing honeycomb and sunburst images, respectively, in the affected area. The patient underwent a biopsy, which led to the diagnosis of intraosseous hemangioma. Having assessed the characteristics of the lesion, it was decided to perform complete excision including safety margins, followed by an iliac crest bone graft to reconstruct the mandible. Awareness of the possible clinical and radiographic presentations of intraosseous hemangioma is considered important, as non-diagnosis could have severe consequences given its possible relation to dental structures.
Decision Making in a Time of Crisis: Drucker’s Recommendations
Jorge Vasconcellos e Sά 피터드러커 소사이어티 2013 창조와 혁신 Vol.6 No.1
This paper focuses on Drucker’s approach to decision making in a time of crisis. A review of Drucker’s work over the last half century, identified Drucker’s four basic concerns in crisis decision making. Those four key areas are: 1) Planned abandonment (yesterday’s activities); 2) analyzing the client: who’s the client?;what is value for him; where is her?; and which of his needs are not satisfied?; 3) redefining the business mission; and 4) taking advantage that one’s company back-office is another’s front office. Crisis are testing times when decision making makes the difference between organizational decay and coming stronger out of the crisis.
Jorge Humberto Dias 강원대학교 인문과학연구소 2015 Journal of Humanities Therapy Vol.6 No.1
This text is the English translation of a resume we made to the doctoral thesis that we presented in February, 2013 at the New University of Lisbon in Portugal. We had also drawn up a structural adjustment, to make possible the publication of this text in the Journal. This is the first thesis developed in Portugal on the basis of a theory for philosophical counselling, based on the work of a Spanish philosopher, Julián Marías, and crossing a theme, happiness, regarded as the great purpose of life and of philosophical counselling. To read more information about the “PROJECT@” method (created by me) in more detail, we suggest the consultation of the bibliography and the footnotes. The innovative nature of our academic text and the fact that this is still only known in the Portuguese language, we consider very important the knowledge of the international community, so that we can open a wider debate as well as a enrichment of our research line.
Improvement of dynamic response in an impact absorber by frictional elements
Jorge Bedolla,Dariusz Szwedowicz,Juan Jiménez,Tadeusz Majewski,Claudia Cortés,Enrique S. Gutierrez-Wing 대한기계학회 2014 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.28 No.4
A novel device that uses friction between one or more pairs of elastic conical rings to dissipate the energy from an impacting body ispresented. The device consists of one moving and one stationary cylinders coupled to each other using two pairs of conical rings and aspring. The spring is used to restore the system to its original configuration after the impact. The dynamic response of the system to theimpact forces during impact events is analysed numerically and experimentally. The effects of several governing parameters, such as themass ratio between the cylinders, the duration of the transient response of the device, the magnitude of the rest zone of the moving elementand the peak impact force are investigated. The proposed system is applicable in sequential impact scenarios, in which remarkableimprovements were observed over traditional solid-rod impact absorbers. The present study may serve as a guide for the design of improveddamping devices for impact applications.