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      • Healthy Life of Korean Patients with Chronic Kidney Failure Undergoing Hemodialysis: A Situation-specific Nursing Theory

        Jinhyang Yang 한국간호과학회 2021 한국간호과학회 학술대회 Vol.2021 No.10

        Aim(s): Chronic kidney failure (CKF) patients have to reorganize their lives around their hemodialysis sessions for their survival. Nursing interventions based on specific theories may promote their health-related behaviors and outcomes. However, few theoretical frameworks or theories are available to guide hemodialysis patients on how to construct their lives under various constraints, while considering their experiences and sociocultural contexts. The purpose of this study was to present a situation-specific theory explaining the healthy life of Korean patients with chronic kidney failure undergoing hemodialysis. Method(s): This study developed a theory based on the integrated approach of Im (2005). The integrated approach includes five steps that could be cyclic: (a) Checking assumptions for theorization; (b) Initiating theorization through multiple sources; (c) Reasoning through critical analyses; (d) Documenting theorization; (e) Reporting and sharing theorization. Reasoning through critical analysis and theorizing was conducted to conceptualize the major concepts and to identify the relationships among concepts. Result(s): The major concepts in the proposed theory include sociocultural context, social networks, individual-level factors, illness experiences, health-related behaviors, and health outcomes. Each major concept includes several relevant subconcepts. A situation-specific theory explains the associations of multiple factors in the healthy lives of Korean CKF patients undergoing hemodialysis within the unique sociocultural context of Korea. Conclusion(s): Nurse and other healthcare professionals could integrate the proposed situation-specific theory into the development of nursing interventions based on this theory to promote health-related behaviors and outcomes of Korean CKF patients undergoing hemodialysis. For these patients, networks of individuals, families, communities, and professionals are essential to promote their healthy lives, not just to keep them alive.

      • KCI등재

        혈액투석 환자 대상 모바일 앱 기반 자가관리 프로그램의 효과

        양진향(Jinhyang Yang),박정준(Jeong-Joon Park) 한국산학기술학회 2023 한국산학기술학회논문지 Vol.24 No.9

        본 연구는 혈액투석 환자를 위한 모바일 앱 기반 자가관리 프로그램을 개발하여 혈액투석 관련 지식, 자기효능감 및 자가관리행위에 미치는 효과를 평가하고자 한다. 모바일 앱은 소프트웨어 원형개발 접근법과 수명주기법을 결합하여 4단계(요구사항 사정 및 분석, 개발, 평가, 적용)를 통해 개발되었다. 본 연구대상자는 2022년 7월부터 11월까지 B시 소재 종합병원 2곳의 혈액투석실을 주 2∼3회 정기적으로 외래 방문하는 환자 51명이다. 수집된 자료는 SPSS 27.0 통계 패키지를 이용하여 기술통계, χ²-test, 독립 t-test와 paired t-test로 분석하였다. 개발된 모바일 앱에 대한 평가가 이루어졌으며, 혈액투석 환자 28명의 사용자 만족도 평가는 4.23점(5점 만점), 의료인 26명의 전문가 평가는 4.22점(5점 만점)이었다. 본 연구의 모바일 앱 기반 자가관리 프로그램을 실험군에게 4주간 적용한 후 대조군과 차이를 비교해 본 결과, 실험군이 대조군보다 혈액투석 관련 지식(t=5.13, p= .000)과 자기효능감(t=2.68, p=.010), 자가관리행위 점수(t=2.82, p=.007)가 유의하게 향상되었다. 따라서 혈액투석 환자들이 접근성과 활용성이 높은 모바일 앱 기반 자가관리 프로그램을 사용한다면 적재적소에서 필요한 정보나 기술을 습득하여 건강관리를 효과적으로 도모할 수 있을 것이다. This study was undertaken to develop a mobile app-based self-management program for hemodialysis patients and evaluate its effectiveness. The mobile app was developed through four phases (needs assessment and analysis, development, evaluation, and application) by combining the software prototyping approach with the life cycle method. The participants were 51 patients who regularly visited the hemodialysis units of two general hospitals in B City, two to three times a week, from July to November 2022. Data were analyzed using descriptive statistics, χ²-test, and independent/paired t-test with the SPSS 27 program. The developed mobile app was evaluated by 28 hemodialysis patients with a user satisfaction rating of 4.23 (out of 5) and 26 healthcare professionals with a rating of 4.22 (out of 5). After applying the mobile app-based self-management program to the experimental group for 4 weeks and comparing the difference with the control group, the experimental group showed significantly improved hemodialysis-related knowledge (t=5.13, p= .000), self-efficacy (t=2.68, p=.010), and self-management behavior (t=2.82, p=.007). Our results indicate that if hemodialysis patients use a mobile app-based self-management program with high accessibility and utilization, they will be able to effectively promote health care by acquiring the necessary information or skills in the right place and right time.

      • Nanoparticulated docetaxel exerts enhanced anticancer efficacy and overcomes existing limitations of traditional drugs

        Choi, Jinhyang,Ko, Eunjung,Chung, Hye-Kyung,Lee, Jae Hee,Ju, Eun Jin,Lim, Hyun Kyung,Park, Intae,Kim, Kab-Sig,Lee, Joo-Hwan,Son, Woo-Chan,Lee, Jung Shin,Jung, Joohee,Jeong, Seong-Yun,Song, Si Yeol,Cho Dove Medical Press 2015 INTERNATIONAL JOURNAL OF NANOMEDICINE Vol.10 No.-

        <P>Nanoparticulation of insoluble drugs improves dissolution rate, resulting in increased bioavailability that leads to increased stability, better efficacy, and reduced toxicity of drugs. Docetaxel (DTX), under the trade name Taxotere™, is one of the representative anticancer chemotherapeutic agents of this era. However, this highly lipophilic and insoluble drug has many adverse effects. Our novel and widely applicable nanoparticulation using fat and supercritical fluid (NUFS™) technology enabled successful nanoscale particulation of DTX (Nufs-DTX). Nufs-DTX showed enhanced dissolution rate and increased aqueous stability in water. After confirming the preserved mechanism of action of DTX, which targets microtubules, we showed that Nufs-DTX exhibited similar effects in proliferation and clonogenic assays using A549 cells. Interestingly, we observed that Nufs-DTX had a greater in vivo tumor growth delay effect on an A549 xenograft model than Taxotere™, which was in agreement with the improved drug accumulation in tumors according to the biodistribution result, and was caused by the enhanced permeability and retention (EPR) effect. Although both Nufs-DTX and Taxotere™ showed negative results for our administration dose in the hematologic toxicity test, Nufs-DTX showed much less toxicity than Taxotere™ in edema, paralysis, and paw-withdrawal latency on a hot plate analysis that are regarded as indicators of fluid retention, peripheral neuropathy, and thermal threshold, respectively, for toxicological tests. In summary, compared with Taxotere™, Nufs-DTX, which was generated by our new platform technology using lipid, supercritical fluid, and carbon dioxide (CO<SUB>2</SUB>), maintained its biochemical properties as a cytotoxic agent and had better tumor targeting ability, better in vivo therapeutic effect, and less toxicity, thereby overcoming the current hurdles of traditional drugs.</P>

      • KCI등재

        직장어린이집 석식에 대한 교사와 부모의 경험과 인식

        유진향 ( Yu Jinhyang ),어성연 ( Auh Seongyeon ) 미래유아교육학회 2023 미래유아교육학회지 Vol.30 No.2

        본 연구는 직장어린이집 석식에 대한 교사와 부모의 경험과 인식, 영유아에 대한 시선, 석식의 방향성을 알아보고자 했다. 자발적 참여 의사를 밝힌 대상 중 직장어린이집 석식 운영을 경험한 교사 10인, 직장어린이집 석식 이용 경험이 있는 부모 3인의 연구참여자를 선정했다. 자료수집은 2021년 4월 한 달간 3그룹 각 2회의 포커스그룹 인터뷰를 진행했으며, 인터뷰 내용을 녹음, 전사, 분석했다. 연구 결과 첫째, 직장어린이집의 석식을 교사는 몸도 마음도 힘든 전쟁 같은 시간으로, 부모는 석식 덕분에 자녀와 보내는 시간적 여유를 얻는 것으로 경험하고 있었다. 이에 따라 교사는 직장어린이집의 석식을 식사의 의미가 퇴색된 시간으로, 부모는 맞벌이 가정 부모의 죄책감을 해소하는 기회로 인식하고 있었다. 둘째, 직장어린이집의 석식에 참여하는 영유아에 대해 교사는 석식 참여를 벌칙과 같이 여긴다고 보았으며, 발달에 부정적 영향이 될 것을 우려하고 있었으나 부모는 부정적인 시선이 없었다. 다만, 가족과 저녁 식사의 추억이 사라지는 것이 안타깝다는 시선은 교사와 부모가 동일하게 보였다. 셋째, 직장어린이집 석식의 방향성에 대해 교사는 석식 이용 자격에 대한 명확한 기준, 석식의 특성을 반영한 교육 제공으로 석식 환경이 개선되길 기대했다. 반면 부모는 직장 내 가족친화제도를 자유롭게 이용할 수 있는 조직문화의 조성, 맞벌이 가정을 위한 밀키트 지원 등 직장어린이집의 석식을 대안할 수 있는 방안을 제안했다. 본 연구결과를 통해 직장어린이집 석식에 대한 교사와 부모의 경험과 인식, 더불어 영유아의 경험도 간접적으로 드러났으며, 직장어린이집에서의 석식을 운영하며 논의되어야 할 부분이 무엇인지 시사한다. The purpose of this study was to explore the experience and awareness of teachers and parents on the dinner at the workplace childcare centers (WCC), children’s eyes on the dinner at WCC, and the right direction of the dinner at WCC. Ten teachers and three parents from WCC experiencing the dinner were recruited. Data were collected during April, 2021 through Focus Group Interviews which were conducted with three independent groups and each group was contacted twice. The results showed that first, the dinner at WCC was considered as strenuous as war by teachers while parents were able to spend a relaxed time with their children due to the dinner. Thus, teachers regarded the dinner as the time that faded the meaning of mealtime whereas parents considered as the opportunity to lessen their sense of guilt as working parents. Second, teachers noticed that children having the dinner at WCC counted the dinner as a penalty and were concerned about the negative aspects of the dinner on children’s development while parents were not. However, both parents and teachers agreed on the point that they were so sorry for the children who were missing their family dinner experiences. Third, teachers expected the improved dinner circumstances by providing the obvious criteria for eligibility of the dinner and the education applying the characteristics of the dinner at WCC. Parents, on the other hand, suggested creating an organizational culture that allows the freedom to freely use family-friendly policies in the workplace and supporting meal kits for working parents as alternative ways to the dinner at WCC. The results of this study suggest the experience and awareness of teachers and parents on the dinner at WCC and the points of the dinner to be discussed, and also, the results indirectly show the children’s experiences on the dinner.

      • KCI등재

        혈액투석 환자를 위한 온라인 자가관리 프로그램의 개발 및 평가

        양진향(Yang, Jinhyang) 기본간호학회 2022 기본간호학회지 Vol.29 No.4

        Purpose: This study was performed to develop and evaluate an online self-management program for enhancing hemodialysis-related knowledge, self-efficacy, ways of coping, self-management behavior, physical and mental health-related quality of life in patients with chronic kidney failure undergoing hemodialysis. Methods: The research used a quasi-experimental design with a non-equivalent control group pre-post test design with convenience sampling. The participants were 53 patients (27 in the experimental group and 26 in the control group). A pretest and posttest were conducted to measure the main variables. For the experimental group, the online self-management program, consisting of counseling-centered activities in small groups, was administered for 8 weeks. Data were analyzed using the x² test, t-test and independent/paired t-test with the SPSS 27 statistics program. Results: Statistically significant increases were found in hemodialysis-related knowledge, self-efficacy, active ways of coping, self-management behavior, physical and mental health-related quality of life but not in passive ways of coping in the experimental group compared to the control group. Conclusion: The results of this study indicate that the online self-management program was effective in increasing hemodialysis-related knowledge, self-efficacy, active ways of coping, self-management behavior, physical and mental health-related quality of life among patients with hemodialysis. Therefore, it can be safely utilized as a nursing intervention for patients with chronic kidney failure undergoing hemodialysis in pandemic situations with high risk of infection.

      • KCI등재

        정신장애인의 삶의 만족에 대한 대인관계의 영향 및 자기효능감의 조절효과

        이진향(Lee Jinhyang) 한국공공사회학회 2021 공공사회연구 Vol.11 No.1

        본 연구는 정신장애인의 대인관계와 자기효능감이 삶의 만족에 미치는 영향력을 살펴보고, 대인관계와 삶의 만족 간의 관계에서 자기효능감의 조절효과를 검증하는 것이 주요 목적이다. 이를 위해 2018년에 실시한 장애인고용패널조사(PSED) 2차 웨이브 3차 자료를 활용하여 조사를 완료한 정신장애인 154명을 대상으로 연구모형을 설정하였다. SPSS 25.0 통계프로그램을 이용하여 기술통계, 상관관계 분석, 위계적 회귀분석을 실시하였다. 분석결과는 다음과 같다. 첫째, 대인관계와 자기효능감은 삶의 만족에 직접적인 긍정적인 영향력을 보였다. 둘째, 대인관계와 정신장애인의 삶의 만족 간 관계에서 자기효능감의 조절효과가 검증되었다. 이는 정신장애인의 삶의 만족도를 높이기 위해 자기효능감 향상을 위한 실천적, 정책적 개입이 무엇보다도 중요함을 의미한다. 분석결과를 바탕으로 연구에 대한 시사점 및 한계점 등을 논의하였다. The main purpose of this study is to examine whether interpersonal relationships and self efficacy affect life satisfaction and to verify whether self-efficacy moderates the relationship between interpersonal relationships and life satisfactions among the mentally disabled. 154 people with mental disabilities were selected using the second wave and third wave of the 2018 PSED. For analysis, descriptive statistics, correlation analysis, and hierarchical regression analysis were performed using the SPSS 25.0 program. The study summarizes the following. First, interpersonal relationships and self-efficacy showed direct influence on life satisfaction. Second, the moderating effect of self-efficacy was verified in the relationship between interpersonal relationships and the life satisfaction of the mentally disabled. This means that practical and policy interventions for improving self-efficacy are of paramount importance in order to increase the level of satisfaction in life for the mentally disabled. Based on the research results, the implications and limitations of the research were discussed.

      • KCI등재

        만성 B형간염환자의 평생건강관리를 위한 모바일 앱 건강관리자용 상담매뉴얼 개발 및 평가

        양진향(Yang, Jinhyang),이혜옥(Lee, Haeok),유경희(Yoo, Kyung Hee) 한국간호교육학회 2014 한국간호교육학회지 Vol.20 No.1

        Purpose: The purpose of this study was to develop and validate health care providers counseling manual in mobile application for lifelong health care among patients with chronic hepatitis B. Methods: The mobile application was developed using a prototyping approach and system developing life cycle method, evaluated by users for their satisfaction with the counseling manual and experts for the quality of the manual. To evaluate application of the counseling manual, knowledge and counselor self-efficacy of the subjects were measured and compared before and after application of the counseling manual. Results: There were statistically significant increases in knowledge and counselor self-efficacy in the user group. A mobile application with high accessibility and applicability including information and counseling factors can promote counseling competence of the nurse as health care provider caring chronic hepatitis B patients. Conclusion: The results of this study indicate that the counseling manual in mobile application is effective in increasing knowledge and counselor self-efficacy among nurses to promote lifelong health care among patients with chronic hepatitis B. Therefore, it can be usefully utilized in the field of nursing for patients with chronic hepatitis B as a nursing intervention.

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