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Jingxian Yu,Hui Dang,Limin Wang 제어·로봇·시스템학회 2018 International Journal of Control, Automation, and Vol.16 No.5
For nonlinear batch processes with actuator faults and external disturbances, a fault-tolerant guaranteed cost controller is proposed based on fuzzy iterative learning control. The linear process model is treated by a sector nonlinear method into a T-S fuzzy faulty model, then the obtained model is transformed into the 2D Roesser equivalent model using the two-dimensional characteristics of batch processes. Based on the obtained model and the Lyapunov stability theory, the quadratic cost function is given and the fault-tolerant guaranteed cost controller guaranteeing that the closed-loop performance index is not more than an upper bound is designed to deal with the actuator fault. The fault-tolerant controller guarantees the stable operation of the faulty system and also has the best system performance with the controller gain and the maximum performance index being solved through constrained optimization. Finally, the simulation on a strong nonlinear reactor is carried out. It shows that the proposed method is more feasible and effective than other methods.
Weiyan Yu,Jiang Song,Jingxian Yu 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.11
A new design method of two-dimensional (2D) controller for multi-phase batch processes with time delay and disturbances is proposed to ensure the stability of the control system and realize efficient production in industry. The batch process is first converted to an equivalent but different dimensional 2D-FM switched system. Based on the 2D system framework, then sufficient conditions of a controller existence expressed by linear matrix inequalities (LMIs) that stabilizing system is given by means of the average dwell time method. Meanwhile, robust hybrid 2D controller design containing extended information is proposed and the minimum runtime lower bound of each sub-system is accurately calculated. The design advantages of the controller depend on the size of the time delay so it has a certain degree of robustness. At the same time, considering the exponential stability, the system can have a faster rate of convergence. In addition, the introduction of extended information has improved the control performance of the system to some extent. The acquisition of minimum time at different phases will promote certain production efficiency and thus reduce energy consumption. Finally, an injection process in industrial production process has been taken as an example to verify effectiveness of the proposed method.
Structural analysis and testing of a miniature flexible joint under pressure and vector loading
Junxue Ren,Xiaoguang Zhang,Jingxian Yang,Chao Wang,Yu Liu,Wei Yang 대한기계학회 2014 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.28 No.9
The structural characteristics of a miniature tactical motor flexible joint subjected to pressure and vector loading were investigated usingfinite element analysis and bench test. Three-dimensional non-linear finite element analysis was conducted using ANSYS Code Version11.0. The axial deflection, vectoring torque, and stress distributions in elastomeric and reinforcement rings were presented. Thepredicted values were consistent with the test data. Results indicate that the axial compressive stiffness increased gradually and nonlinearlywith pressure, while the angular stiffness remained nearly constant in the vectoring angle range from 0° to 6°. Under pressureloading, the elastomeric shear stress was negative, high at both sides, and low at the center of the cross-section, while the reinforcementhoop stress was compressive at the inner radius and tensile at the outer radius. The compressive stress was also high. The flexible jointexhibited higher stress level with altered stress distribution when subjected to additional vector loading. Existing empirical formulas forreinforcement hoop compressive stress were determined to be not applicable to the miniature flexible joint, which significantly overestimatedthe stress caused by pressure and underestimated the stress caused by vectoring.
Symptom Experience and Related Predictors in Liver Transplantation Recipients
Xiao Chen,Yuxia Zhang,Jingxian Yu 한국간호과학회 2021 Asian Nursing Research Vol.15 No.1
Purpose: Symptom experience after liver transplantation (LT) provides healthcare professionals with important information about the benefits and limitations of LT from patients’ perspective. This study aims to explore the multidimensional symptom experience and analyze related predictive factors in LT recipients. Methods: This cross-sectional study evaluated the occurrence, frequency, intensity, and level of distress of 40 symptoms in 265 LT recipients. Stepwise multiple regression analysis was performed to analyze the influencing factors of symptom experience. Results: The analysis of patient-reported data indicated that the ten most common symptoms were fatigue (42.3%), frequent sleep interruptions (38.9%), difficulty falling asleep (35.9%), decreased memory (34.0%), dreaminess (29.8%), itch (28.7%), muscular weakness (26.4%), shortness of breath (25.3%), anxiety (24.5%), and hand tremor (21.9%). Patients were classified into four groups according to survival time (1-month, 2e6-month, 7e12-month, and >1-year groups) after LT, and the most common symptom was fatigue in the one-month and 2e6-month groups, difficulty falling asleep in the 7e12-month group, and decreased memory in the >1-year group. Type of the primary caregiver, complications, concerns about the decreased ability to perform household and outdoor activities, and concerns about being a burden to the family were predictors of symptoms burden. Conclusion: LT recipients experienced complicated symptoms. In clinical practice, it is critical to integrate physicians, nurses, and social workers as a medical team to help LT recipients develop suitable coping strategies that can potentially address patients’ concerns, increase the sense of confidence, and improve symptom outcomes.
Nature engineered diatom biosilica as drug delivery systems
Uthappa, U.T.,Brahmkhatri, Varsha,Sriram, G.,Jung, Ho-Young,Yu, Jingxian,Kurkuri, Nikita,Aminabhavi, Tejraj M.,Altalhi, Tariq,Neelgund, Gururaj M.,Kurkuri, Mahaveer D. Elsevier 2018 Journal of controlled release Vol.281 No.-
<P><B>Abstract</B></P> <P>Diatoms, unicellular photosynthetic algae covered with siliceous cell wall, are also called frustule. These are the most potential naturally available materials for the development of cost-effective drug delivery systems because of their excellent biocompatibility, high surface area, low cost and ease of surface modification. Mesoporous silica materials such as MCM–41 and SBA–15 have been extensively used in drug delivery area. Their synthesis is challenging, time consuming, requires toxic chemicals and are energy intensive, making the entire process expensive and non-viable. Therefore, it is necessary to explore alternative materials. Surprisingly, nature has provided some exciting materials called diatoms; biosilica is one such a material that can be potentially used as a drug delivery vehicle. The present review focuses on different types of diatom species used in drug delivery with respect to their structural properties, morphology, purification process and surface functionalization. In this review, recent advances along with their limitations as well as the future scope to develop them as potential drug delivery vehicles are discussed.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>